ROS production by adrenodoxin does not cause apoptosis in fission yeast

Apoptosis

Volumn 12, Issue 12, 2007, Pages 2135-2142

  Derouet Hümbert, Evi ^a   Drǎgan, Cǎlin Aurel ^a   Hakki, Tarek ^a   Bureik, Matthias ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Adrenodoxin; Apoptosis; Cytochrome P450 system; Fission yeast; Mitochondria; Reactive oxygen species

Indexed keywords

ADRENODOXIN; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; FLOW CYTOMETRY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; SCHIZOSACCHAROMYCES POMBE; WILD TYPE; YEAST;

ADRENODOXIN; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CATTLE; CORTODOXONE; HUMANS; HYDROCORTISONE; HYDROGEN PEROXIDE; MICROBIAL VIABILITY; MUTANT PROTEINS; REACTIVE OXYGEN SPECIES; SCHIZOSACCHAROMYCES; STEROID 11-BETA-HYDROXYLASE; TIME FACTORS;

MAMMALIA; SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

EID: 35948985473     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-007-0133-1     Document Type: Article

References (35)

1. Fadeel B, Orrenius S (2005) Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease. J Intern Med 258:479-517
2. Frohlich KU, Fussi H, Ruckenstuhl C (2007) Yeast apoptosis - from genes to pathways. Semin Cancer Biol 17:112-121
3. Cairns J (2002) A DNA damage checkpoint in Escherichia coli. DNA Repair (Amst) 1:699-701
4. Ink B, Zornig M, Baum B et al (1997) Human Bak induces cell death in Schizosaccharomyces pombe with morphological changes similar to those with apoptosis in mammalian cells. Mol Cell Biol 17:2468-2474
5. Burhans WC, Weinberger M, Marchetti MA et al (2003) Apoptosis-like yeast cell death in response to DNA damage and replication defects. Mutat Res 532:227-243
6. Marchetti MA, Weinberger M, Murakami Y, Burhans WC, Huberman JA (2006) Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeast. J Cell Sci 119:124-131
7. Poon B, Jowett JB, Stewart SA et al (1997) Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard. J Virol 71:3961-3971
8. Somasundaran M, Sharkey M, Brichacek B et al (2002) Evidence for a cytopathogenicity determinant in HIV-1 Vpr. Proc Natl Acad Sci USA 99:9503-9508
9. Le Rouzic E, Benichou S (2005) The Vpr protein from HIV-1: distinct roles along the viral life cycle. Retrovirology 2:11
10. Zhao Y, Cao J, O'Gorman MR, Yu M, Yogev R (1996) Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe. J Virol 70:5821-5826
11. Zhao Y, Yu M, Chen M et al (1998) Pleiotropic effects of HIV-1 protein R (Vpr) on morphogenesis and cell survival in fission yeast and antagonism by pentoxifylline. Virology 246:266-276
12. Benko Z, Liang D, Agbottah E et al (2004) Anti-Vpr activity of a yeast chaperone protein. J Virol 78:11016-11029
13. Benko Z, Liang D, Agbottah E et al (2007) Antagonistic interaction of HIV-1 Vpr with Hsf-mediated cellular heat shock response and Hsp16 in fission yeast (Schizosaccharomyces pombe). Retrovirology 4:16
14. Zelivianski S, Liang D, Chen M, Mirkin BL, Zhao RY (2006) Suppressive effect of elongation factor 2 on apoptosis induced by HIV-1 viral protein R. Apoptosis 11:377-388
15. Rodriguez-Menocal L, D'Urso G (2004) Programmed cell death in fission yeast. FEMS Yeast Res 5:111-117
16. Gould KL, Nurse P (1989) Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature 342:39-45
17. Castedo M, Perfettini JL, Roumier T, Kroemer G (2002) Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe. Cell Death Differ 9:1287-1293
18. Castedo M, Perfettini JL, Roumier T et al (2004) Cell death by mitotic catastrophe: a molecular definition. Oncogene 23:2825-2837
19. Fisher A. (1988) Intracellular production of oxygen-derived free radicals. In: Halliwell B (ed) Oxygen radicals, tissue injury. FASEB Publishing, Bethesda, MD, pp 34-39
20. Derouet-Hümbert E, Römer K, Bureik M (2005) Adrenodoxin (Adx) and CYP11A1 (P450scc) induce apoptosis by the generation of reactive oxygen species in mitochondria. Biol Chem 386:453-461
21. Eisenberg T, Buttner S, Kroemer G, Madeo F (2007) The mitochondrial pathway in yeast apoptosis. Apoptosis 12:1011-1023
22. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Press, Cold Spring Harbor, NY
23. Alfa C, Fantes P, Hyams J, McLeod M, Warbrick E (1993) Experiments with fission yeast. A laboratory course manual. Cold Spring Harbor Press, Cold Spring Harbor, NY
24. Moreno S, Klar A, Nurse P (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Meth Enzymol 194:795-823
25. Bureik M, Schiffler B, Hiraoka Y, Vogel F, Bernhardt R (2002) Functional expression of human mitochondrial CYP11B2 in fission yeast and identification of a new internal electron transfer protein, etp1. Biochemistry 41:2311-2321
26. Maundrell K (1990) nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine. J Biol Chem 265:10857-10864
27. Dragan C-A, Zearo S, Hannemann F, Bernhardt R, Bureik M (2005) Efficient conversion of 11-deoxycortisol to cortisol (hydrocortisone) by recombinant fission yeast Schizosaccharomyces pombe. FEMS Yeast Res 5:621-625
28. Hakki T, Zearo S, Dragan CA, Bureik M, Bernhardt R (in press) Coexpression of redox partners increases the hydrocortisone (cortisol) production efficiency in CYP11B1 expressing fission yeast Schizosaccharomyces pombe. J Biotechnol
29. Hannemann F, Bichet A, Ewen KM, Bernhardt R (2006) Cytochrome P450 systems-biological variations of electron transport chains. Biochim Biophys Acta 1770:330-344
30. Uhlmann H, Iametti S, Vecchio G, Bonomi F, Bernhardt R (1997) Pro108 is important for folding and stabilization of adrenal ferredoxin, but does not influence the functional properties of the protein. Eur J Biochem 248:897-902
31. Schiffler B, Kiefer M, Wilken A et al (2001) The interaction of bovine adrenodoxin with CYP11A1 (cytochrome P450scc) and CYP11B1 (cytochrome P45011β). Acceleration of reduction and substrate conversion by site-directed mutagenesis of adrenodoxin. J Biol Chem 276:36225-36232
32. Bichet A, Hannemann F, Rekowski M, Bernhardt R (2007) A new application of the yeast two-hybrid system in protein engineering. Protein Eng Des Sel 20:117-123
33. Dragan CA, Blank LM, Bureik M (2006) Increased TCA cycle activity and reduced oxygen consumption during cytochrome P450-dependent biotransformation in fission yeast. Yeast 23:779-794
34. Ehmer PB, Bureik M, Bernhardt R, Müller U, Hartmann RW (2002) Development of a test system for inhibitors of human aldosterone synthase (CYP11B2): screening in fission yeast and evaluation of selectivity in V79 cells. J Steroid Biochem Mol Biol 81:173-179
35. Bureik M, Hübel K, Dragan C-A et al (2004) Development of test systems for the discovery of selective human aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) inhibitors. Discovery of a new lead compound for the therapy of congestive heart failure, myocardial fibrosis and hypertension. Mol Cell Endocrinol 217:249-254