Adrenodoxin (Adx) and CYP11A1 (P450scc) induce apoptosis by the generation of reactive oxygen species in mitochondria

Biological Chemistry

Volumn 386, Issue 5, 2005, Pages 453-461

  Derouet Hümbert, Evi ^a   Roemer, Klaus ^b   Bureik, Matthias ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Adrenodoxin; Apoptosis CYP11A1; Cytochrome P450; Electron transfer chain; Mitochondria; Reactive oxygen species; Steroid hydroxylation

Indexed keywords

ADRENODOXIN; CASPASE; CYTOCHROME C; CYTOCHROME P450; CYTOCHROME P450 11A1; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL STRAIN HCT116; CELL VIABILITY; ELECTRON TRANSPORT; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; STEROID HYDROXYLATION; TUMOR SUPPRESSOR GENE;

ADRENODOXIN; ANIMALS; APOPTOSIS; CASPASES; CATTLE; CELL LINE; CELL SURVIVAL; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYTOCHROMES C; ENZYME ACTIVATION; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

BOVINAE; MAMMALIA;

EID: 26844443129     PISSN: 14316730     EISSN: 14316730     Source Type: Journal    
DOI: 10.1515/BC.2005.054     Document Type: Article

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