Polymorphisms in IGF-binding protein 1 are associated with impaired renal function in type 2 diabetes

Diabetes

Volumn 54, Issue 12, 2005, Pages 3547-3553

  Stephens, Richard H ^a,b   McElduff, Patrick ^b   Heald, Adrian H ^a   New, John P ^a   Worthington, Jane ^c   Ollier, William E ^b   Gibson, J Martin ^a  

^a HOPE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; INTEGRIN; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN C;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; EXON; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; KIDNEY DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MICROANGIOPATHY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN POLYMORPHISM; REGISTER; RENAL PROTECTION; SINGLE NUCLEOTIDE POLYMORPHISM;

BASE SEQUENCE; CHROMOSOME MAPPING; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DIABETIC NEPHROPATHIES; DNA PRIMERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 33644680756     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/diabetes.54.12.3547     Document Type: Article

References (38)

1. Gibson JM, Westwood M, Crosby SR, Gordon C, Holly JM, Fraser W, Anderson C, White A, Young RJ: Choice of treatment affects plasma levels of insulin-like growth factor-binding protein-1 in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 80:1369-1375, 1995
2. Gibson JM, Westwood M, Young RJ, White A: Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM). J Clin Endocrinol Metab 81:860-863, 1996
3. Fervenza F, Green A, Lafayette RA: Acute renal failure due to postinfectious glomerulonephritis during pregnancy. Am J Kidney Dis 29:273-276, 1997
4. Park IS, Kiyomoto H, Alvarez F, Xu YC, Abboud HE, Abboud SL: Preferential expression of insulin-like growth factor binding proteins-1, -3, and -5 during early diabetic renal hypertrophy in rats. Am J Kidney Dis 32:1000-1010, 1998
5. Heald AH, Cruickshank JK, Riste LK, Cade JE, Anderson S, Greenhalgh A, Sampayo J, Taylor W, Fraser W, White A, Gibson JM: Close relation of fasting insulin-like growth factor binding protein-1 (IGFBP-1) with glucose tolerance and cardiovascular risk in two populations. Diabetologia 44:333-339, 2001
6. Cruickshank JK, Heald AH, Anderson S, Cade JE, Sampayo J, Riste LK, Greenhalgh A, Taylor W, Fraser W, White A, Gibson JM: Epidemiology of the insulin-like growth factor system in three ethnic groups. Am J Epidemiol 154:504-513, 2001
7. Vaessen N, Heutink P, Janssen JA, Witteman JC, Testers L, Hofman A, Lamberts SW, Oostra BA, Pols HA, van Duijn CM: A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction. Diabetes 50:637-642, 2001
8. Heald AH, Siddals KW, Fraser W, Taylor W, Kaushal K, Morris J, Young RJ, White A, Gibson JM: Low circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) are closely associated with the presence of macrovascular disease and hypertension in type 2 diabetes. Diabetes 51:2629-2636, 2002
9. Sandhu MS, Heald AH, Gibson JM, Cruickshank JK, Dunger DB, Wareham NJ: Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study. Lancet 359:1740-1745, 2002
10. Heald AH, Anderson SG, Ivison F, Laing I, Gibson JM, Cruickshank K: C-reactive protein and the insulin-like growth factor (IGF) system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis 170:79-86, 2003
11. Juul A: Serum levels of insulin-like growth factor I and its binding proteins in health and disease. Growth Horm IGF Res 13:113-170, 2003
12. Sandhu MS, Gibson JM, Heald AH, Dunger DB, Wareham NJ: Low circulating IGF-II concentrations predict weight gain and obesity in humans. Diabetes 52:1403-1408, 2003
13. Poulaki V, Joussen AM, Mitsiades N, Mitsiades CS, Iliaki EF, Adamis AP: Insulin-like growth factor-I plays a pathogenetic role in diabetic retinopathy. Am J Pathol 165:457-469, 2004
14. Jones JI, Clemmons DR: Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3-34, 1995
15. Baxter RC: Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivity. Am J Physiol 278:E967-E976, 2000
16. Lee PD, Giudice LC, Conover CA, Powell DR: Insulin-like growth factor binding protein-1: recent findings and new directions. Proc Soc Exp Biol Med 216:319-357, 1997
17. Goswami R, Lacson R, Yang E, Sam R, Unterman T: Functional analysis of glucocorticoid and insulin response sequences in rat insulin-like growth factor-binding protein-1 promoter. Endocrinology 134:736-743, 1994
18. Suwanichkul A, Allander SV, Morris SL, Powell DR: Glucocorticoids and insulin regulate expression of the human gene for insulin-like growth factor-binding protein-1 through proximal promoter elements. J Biol Chem 269:30835-30841, 1994
19. Tazuke SI, Mazure NM, Sugawara J, Carland G, Faessen GH, Suen L-F, Irwin JC, Powell DR, Giaccia AJ, Giudice LC: Hypoxia stimulates insulin-like growth factor binding protein 1 (IGFBP-1) gene expression in HepG2 cells: a possible model for IGFBP-1 expression in fetal hypoxia. Proc Natl Acad Sci U S A 95:10188-10193, 1998
20. Sugawara J, Tazuke SI, Suen LF, Powell DR, Kaper F, Giaccia AJ, Giudice LC: Regulation of insulin-like growth factor-binding protein 1 by hypoxia and 3′,5′-cyclic adenosine monophosphate is additive in HepG2 cells. J Clin Endocrinol Metab 85:3821-3827, 2000
21. Krones A, Jungermann K, Kietzmann T: Cross-talk between the signals hypoxia and glucose at the glucose response element of the L-type pyruvate kinase gene. Endocrinology 142:2707-2718, 2001
22. Nakae J, Kitamura T, Silver DL, Accili D: The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest 108:1359-1367, 2001
23. Kaufman CR, Catanese VM: Pre- and post-translational regulation of renal insulin-like growth factor binding protein-1 in insulin-deficient diabetes. J Investig Med 43:178-186, 1995
24. Segev Y, Landau D, Marbach M, Shehadeh N, Flyvbjerg A, Phillip M: Renal hypertrophy in hyperglycemic non-obese diabetic mice is associated with persistent renal accumulation of insulin-like growth factor I. J Am Soc Nephrol 8:436-444, 1997
25. Miyatake N, Shikata K, Wada J, Sugimoto H, Takahashi S, Makino H: Differential distribution of insulin-like growth factor-1 and insulin-like growth factor binding proteins in experimental diabetic rat kidney. Nephron 81:317-323, 1999
26. van Kleffens M, Lindenbergh-Kortleve DJ, Koster JG, van Neck JW, Flyvbjerg A, Rasch R, Drop SL, van Buul-Offers SC: The role of the IGF axis in IGFBP-1 and IGF-I induced renal enlargement in Snell dwarf mice. J Endocrinol 170:333-346, 2001
27. Feldmann B, Jehle PM, Mohan S, Lang GE, Lang GK, Brueckel J, Boehm BO: Diabetic retinopathy is associated with decreased serum levels of free IGF-I and changes of IGF-binding proteins. Growth Horm IGF Res 10:53-60, 2000
28. Tregouet DA, Tiret L: Cox proportional hazards survival regression in haplotype-based association analysis using the Stochastic-EM algorithm. Eur J Hum Genet 12:971-974, 2004
29. Levey AS, Greene T, Beck GJ, Caggiula AW, Kusek JW, Hunsicker LG, Klahr S: Dietary protein restriction and the progression of chronic renal disease; what have all of the results of the MDRD study shown? Modification of Diet in Renal Disease Study group. J Am Soc Nephrol 10:2426-2439, 1999
30. Feld S, Hirschberg R: Growth hormone, the insulin-like growth factor system, and the kidney. Endocr Rev 17:423-480, 1996
31. Landau D, Israel E, Rivkis I, Kachko L, Schrijvers BF, Flyvbjerg A, Phillip M, Segev Y: The effect of growth hormone on the development of diabetic kidney disease in the rat. Nephrol Dial Transplant 18:694-702, 2003
32. Raz I, Rubinger D, Popovtzer M, Grønbank H, Weiss O, Flyvbejerg A: Octreotide prevents the early increase in renal insulin-like growth factor binding protein 1 in steptozotocin diabetic rats. Diabetes 47:924-930, 1998
33. Flyvbjerg A, Frystyk J, Østerby R, Ørskov H: Kidney IGF-I and renal hypertrophy in GH-deficient dwarf rats. Am J Physiol 262:E956-E962, 1992
34. O'Brien RM, Streeper RS, Ayala JE, Stadelmaier BT, Hornbuckle LA: Insulin-regulated gene expression. Biochem Soc Trans 29:552-558, 2001
35. Hall RK, Yamasaki T, Kucera T, Waltner-Law M, O'Brien R, Granner DK: Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. J Biol Chem 275: 30169-30175, 2000
36. Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, Bunn HF, Livingston DM: An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci U S A 93:12969-12973, 1996
37. Vallet VS, Casado M, Henrion AA, Bucchin D, Raymondjean M, Kahn A, Vaulont S: Differential roles of upstream stimulatory factors 1 and 2 in the transcriptional response of liver genes to glucose. J Bio. Chem 273:20175-20179, 1998
38. Fowlkes JL, Serra DM, Bunn RC, Thrailkill KM, Enghild JJ, Nagase H: Regulation of insulin-like growth factor (IGF)-I action by matrix metalloproteinase-3 involves selective disruption of IGF-I/IGF-binding protein-3 complexes. Endocrinology 145:620-626, 2004