-
1
-
-
33745307617
-
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 2006;441:424-30.
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 2006;441:424-30.
-
-
-
-
2
-
-
28844448182
-
Oncogenic PI3K deregulates transcription and translation
-
Bader AG, Kang S, Zhao L, Vogt PK. Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer 2005;5:921-9.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 921-929
-
-
Bader, A.G.1
Kang, S.2
Zhao, L.3
Vogt, P.K.4
-
3
-
-
25444482837
-
Mutated PI 3-kinases: Cancer targets on a silver platter
-
Kang S, Bader AG, Zhao L, Vogt PK. Mutated PI 3-kinases: cancer targets on a silver platter. Cell Cycle 2005;4:578-81.
-
(2005)
Cell Cycle
, vol.4
, pp. 578-581
-
-
Kang, S.1
Bader, A.G.2
Zhao, L.3
Vogt, P.K.4
-
4
-
-
33646706052
-
Oncogenic PI3K and its role in cancer
-
Samuels Y, Ericson K. Oncogenic PI3K and its role in cancer. Curr Opin Oncol 2006;18:77-82.
-
(2006)
Curr Opin Oncol
, vol.18
, pp. 77-82
-
-
Samuels, Y.1
Ericson, K.2
-
5
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell IG, Russell SE, Choong DY, et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004;64:7678-81.
-
(2004)
Cancer Res
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.3
-
6
-
-
20444374445
-
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
-
Samuels Y, Diaz LA, Jr., Schmidt-Kittler O, et al. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell 2005;7:561-73.
-
(2005)
Cancer Cell
, vol.7
, pp. 561-573
-
-
Samuels, Y.1
Diaz Jr., L.A.2
Schmidt-Kittler, O.3
-
7
-
-
28244479028
-
Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells
-
Isakoff SJ, Engelman JA, Irie HY, et al. Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells. Cancer Res 2005;65:10992-1000.
-
(2005)
Cancer Res
, vol.65
, pp. 10992-11000
-
-
Isakoff, S.J.1
Engelman, J.A.2
Irie, H.Y.3
-
8
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004;304:554.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
-
9
-
-
32244445352
-
PIK3CA mutation and histological type in breast carcinoma: High frequency of mutations in lobular carcinoma
-
Buttitta F, Felicioni L, Barassi F, et al. PIK3CA mutation and histological type in breast carcinoma: high frequency of mutations in lobular carcinoma. J Pathol 2006;208:350-5.
-
(2006)
J Pathol
, vol.208
, pp. 350-355
-
-
Buttitta, F.1
Felicioni, L.2
Barassi, F.3
-
11
-
-
0017148259
-
A general method for isolation of high molecular weight DNA from eukaryotes
-
Blin N, Stafford DW. A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res 1976;3:2303-8.
-
(1976)
Nucleic Acids Res
, vol.3
, pp. 2303-2308
-
-
Blin, N.1
Stafford, D.W.2
-
12
-
-
20044364933
-
EGFR mutations in non-small-cell lung cancer: Analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
-
Marchetti A, Martella C, Felicioni L, et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 2005;23:857-65.
-
(2005)
J Clin Oncol
, vol.23
, pp. 857-865
-
-
Marchetti, A.1
Martella, C.2
Felicioni, L.3
-
13
-
-
17144382038
-
Frequent mutation of the PIK3CA gene in ovarian and breast cancers
-
Levine DA, Bogomolniy F, Yee CJ, et al. Frequent mutation of the PIK3CA gene in ovarian and breast cancers. Clin Cancer Res 2005;11:2875-8.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2875-2878
-
-
Levine, D.A.1
Bogomolniy, F.2
Yee, C.J.3
-
14
-
-
20144387695
-
PIK3C A mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
-
Saal LH, Holm K, Maurer M, et al. PIK3C A mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. Cancer Res 2005;65:2554-9.
-
(2005)
Cancer Res
, vol.65
, pp. 2554-2559
-
-
Saal, L.H.1
Holm, K.2
Maurer, M.3
-
15
-
-
33846854921
-
Clinicopathologic analysis of breast cancers with PIK3CA mutations in Japanese women
-
Maruyama N, Miyoshi Y, Taguchi T, Tamaki Y, Monden M, Noguchi S. Clinicopathologic analysis of breast cancers with PIK3CA mutations in Japanese women. Clin Cancer Res 2007;15:408-14.
-
(2007)
Clin Cancer Res
, vol.15
, pp. 408-414
-
-
Maruyama, N.1
Miyoshi, Y.2
Taguchi, T.3
Tamaki, Y.4
Monden, M.5
Noguchi, S.6
-
16
-
-
0037021259
-
Infiltrating ductal and lobular breast carcinomas are characterised by different interrelationships among markers related to angiogenesis and hormone dependence
-
Coradini D, Pellizzaro C, Veneroni S, Ventura L, Daidone MG. Infiltrating ductal and lobular breast carcinomas are characterised by different interrelationships among markers related to angiogenesis and hormone dependence. Br J Cancer 2002;87:1105-11.
-
(2002)
Br J Cancer
, vol.87
, pp. 1105-1111
-
-
Coradini, D.1
Pellizzaro, C.2
Veneroni, S.3
Ventura, L.4
Daidone, M.G.5
-
17
-
-
0027423039
-
p53 mutations and histological type of invasive breast carcinoma
-
Marchetti A, Buttitta F, Pellegrini S, et al. p53 mutations and histological type of invasive breast carcinoma. Cancer Res 1993;53:4665-9.
-
(1993)
Cancer Res
, vol.53
, pp. 4665-4669
-
-
Marchetti, A.1
Buttitta, F.2
Pellegrini, S.3
-
18
-
-
0027716808
-
p53 mutations and histologic type of invasive breast carcinoma. A polymerase chain reaction-single-strand conformation polymorphism and immunohistochemical analysis p53 mutations and histological type of invasive breast carcinoma
-
Marchetti A, Buttitta F, Pellegrini S, et al. p53 mutations and histologic type of invasive breast carcinoma. A polymerase chain reaction-single-strand conformation polymorphism and immunohistochemical analysis p53 mutations and histological type of invasive breast carcinoma. Ann N Y Acad Sci 1993;698:114-9.
-
(1993)
Ann N Y Acad Sci
, vol.698
, pp. 114-119
-
-
Marchetti, A.1
Buttitta, F.2
Pellegrini, S.3
-
19
-
-
23044467557
-
Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit
-
Shekar SC, Wu H, Fu Z, et al. Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit. J Biol Chem 2005;280:27850-5.
-
(2005)
J Biol Chem
, vol.280
, pp. 27850-27855
-
-
Shekar, S.C.1
Wu, H.2
Fu, Z.3
-
20
-
-
21144457217
-
Functional analysis of PIK3CA gene mutations in human colorectal cancer
-
Ikenoue T, Kanai F, Hikiba Y, et al. Functional analysis of PIK3CA gene mutations in human colorectal cancer. Cancer Res 2005;65:4562-7.
-
(2005)
Cancer Res
, vol.65
, pp. 4562-4567
-
-
Ikenoue, T.1
Kanai, F.2
Hikiba, Y.3
-
21
-
-
33748063941
-
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
-
McCubrey JA, Steelman LS, Abrams SL, et al. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Adv Enzyme Regul 2006;46:249-79.
-
(2006)
Adv Enzyme Regul
, vol.46
, pp. 249-279
-
-
McCubrey, J.A.1
Steelman, L.S.2
Abrams, S.L.3
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