Dopamine acutely decreases type 3 Na+/H+ exchanger activity in renal OK cells through the activation of protein kinases A and C signalling cascades

European Journal of Pharmacology

Volumn 488, Issue 1-3, 2004, Pages 51-59

  Gomes, Pedro ^a   Soares Da Silva, Patrício ^a  

^a Institute of Pharmacology and Therapeutics   (Portugal)

Author keywords

Dopamine D1 like receptor; Na+ H+ exchanger; OK cell; Protein kinase

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 BROMO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL; ADENYLATE CYCLASE; ANTIBODY; BUCLADESINE; CHELERYTHRINE; CHOLERA TOXIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHORBOL DIBUTYRATE; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; QUINELORANE; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN 3;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; KIDNEY CELL; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE; ADENYLATE CYCLASE; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE; DOPAMINE AGONISTS; HYDROGEN-ION CONCENTRATION; KIDNEY; KINETICS; NA(+)-K(+)-EXCHANGING ATPASE; OPOSSUMS; PHOSPHOLIPASE C; PROTEIN KINASE C; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER;

EID: 1642267292     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.02.011     Document Type: Article

References (50)

1. Albrecht F.E., Xu J., Moe O.W., Hopfer U., Simonds W.F., Orlowski J., Jose P.A. Regulation of NHE3 activity by G protein subunits in renal brush-border membranes. Am. J. Physiol., Regul. Integr. Comp. Physiol. 278:2000;R1064-R1073.
2. +-Pi cotransport in a subclone of opossum kidney cells (OK-7A) by a genomic mechanism. Am. J. Physiol. 264:1993;F404-F410.
3. +-ATPase activity in rat proximal convoluted tubule segments. Am. J. Physiol. 252:1987;F39-F45.
4. + exchanger NHE-3 isoform in renal cells (OK) via a dual signaling cascade involving protein kinase A and C. J. Biol. Chem. 270:1995;20004-20010.
5. 2 receptors. Am. J. Physiol. 259:1990;F924-F928.
6. Blaxall H.S., Cerutis D.R., Hass N.A., Iversen L.J., Bylund D.B. Cloning and expression of the alpha 2C-adrenergic receptor from the OK cell line. Mol. Pharmacol. 45:1994;176-181.
7. Bleasdale J.E., Thakur N.R., Gremban R.S., Bundy G.L., Fitzpatrick F.A., Smith R.J., Bunting S. Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. J. Pharmacol. Exp. Ther. 255:1990;756-768.
8. Brunskill N.J., Morrissey J.J., Klahr S. G-protein stimulation inhibits amiloride-sensitive Na/H exchange independently of cyclic AMP. Kidney Int. 42:1992;11-17.
9. + exchange via a cAMP-dependent mechanism. Am. J. Physiol. 259:1990;F977-F985.
10. Cole J.A., Forte L.R., Krause W.J., Thorne P.K. Clonal sublines that are morphologically and functionally distinct from parental OK cells. Am. J. Physiol. 256:1989;F672-F679.
11. + exchanger 3 in opossum kidney cells. J. Am. Soc. Nephrol. 14:2003;1720-1730.
12. Donowitz M., Janecki A., Akhter S., Cavet M.E., Sanchez F., Lamprecht G., Zizak M., Kwon W.L., Khurana S., Yun C.H., Tse C.M. Short-term regulation of NHE3 by EGF and protein kinase C but not protein kinase A involves vesicle trafficking in epithelial cells and fibroblasts. Ann. N. Y. Acad. Sci. 915:2000;30-42.
13. i protein. Cell Signal. 3:1991;547-557.
14. + exchanger activity in renal BBMV by stimulation of adenylate cyclase. Am. J. Physiol. 259:1990;F297-F303.
15. 1 dopamine agonists. Am. J. Physiol. 264:1993;F1032-F1037.
16. Force T., Bonventre J.V., Flannery M.R., Gorn A.H., Yamin M., Goldring S.R. A cloned porcine renal calcitonin receptor couples to adenylyl cyclase and phospholipase C. Am. J. Physiol., Renal Fluid Electrolyte Physiol. 262:1992;F1110-F1115.
17. Francesconi A., Duvoisin R.M. Role of the second and third intracellular loops of metabotropic glutamate receptors in mediating dual signal transduction activation. J. Biol. Chem. 273:1998;5615-5624.
18. + exchanger. Am. J. Physiol. 258:1990;F514-F521.
19. +-ATPase activity. Am. J. Physiol., Renal Physiol. 282:2002;F1084-F1096.
20. + exchanger. Am. J. Physiol., Regul. Integr. Comp. Physiol. 281:2001;R10-R18.
21. Gomes P., Xu J., Serrao P., Doria S., Jose P.A., Soares-da-Silva P. Expression and function of sodium transporters in two opossum kidney cell clonal sublines. Am. J. Physiol., Renal Physiol. 283:2002;F73-F85.
22. + exchanger isoform NHE8. Am. J. Physiol., Renal Physiol. 84:2003;F467-F473.
23. + exchangers. Ann. N. Y. Acad. Sci. 976:2002;248-258.
24. Hegde S.S., Jadhav A.L., Lokhandwala M.F. Role of kidney dopamine in the natriuretic response to volume expansion in rats. Hypertension. 13:1989;828-834.
25. Hussain T., Lokhandwala M.F. Renal dopamine receptor function in hypertension. Hypertension. 32:1998;187-197.
26. Jose P.A., Raymond J.R., Bates M.D., Aperia A., Felder R.A., Carey R.M. The renal dopamine receptors. J. Am. Soc. Nephrol. 2:1992;1265-1278.
27. Jose P.A., Eisner G.M., Felder R.A. Renal dopamine receptors in health and hypertension. Pharmacol. Ther. 80:1998;149-182.
28. Jose P.A., Eisner G.M., Felder R.A. Renal dopamine and sodium homeostasis. Curr. Hypertens. Rep. 2:2000;174-183.
29. + exchanger in luminal membrane vesicles isolated from cortical tubules. Am. J. Physiol. 277:1999;F773-F778.
30. Koyama H., Goodpasture C., Miller M.M., Teplitz R.L., Riggs A.D. Establishment and characterization of a cell line from the American opossum (Didelphys virginiana). In Vitro. 14:1978;239-246.
31. Kuhn B., Schmid A., Harteneck C., Gudermann T., Schultz G. G proteins of the Gq family couple the H2 histamine receptor to phospholipase C. Mol. Endocrinol. 10:1996;1697-1707.
32. + exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms. J. Biol. Chem. 272:1997;28672-28679.
33. 2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes. Am. J. Physiol., Cell Physiol. 285:2003;C1527-C1536.
34. 1-Adrenergic receptors activate NHE1 and NHE3 through distinct signaling pathways in epithelial cells. Am. J. Physiol., Renal Physiol. 280:2001;F415-F425.
35. 1 receptor: selective potentiation by protein kinase A. Mol. Endocrinol. 6:1992;1815-1824.
36. Moe O.W. Acute regulation of proximal tubule apical membrane Na/H exchanger NHE-3: role of phosphorylation, protein trafficking, and regulatory factors. J. Am. Soc. Nephrol. 10:1999;2412-2425.
37. + exchanger isoforms. Am. J. Physiol. 268:1995;C283-C296.
38. + exchanger isoforms (NHE1 and NHE3) in polarized epithelial cell lines. J. Cell Sci. 109:1996;929-939.
39. Pelayo J.C., Fildes R.D., Eisner G.M., Jose P.A. Effects of dopamine blockade on renal sodium excretion. Am. J. Physiol. 245:1983;F247-F253.
40. Pfister M.F., Forgo J., Ziegler U., Biber J., Murer H. cAMP-dependent and -independent downregulation of type II Na-Pi cotransporters by PTH. Am. J. Physiol., Renal Physiol. 276:1999;F720-F725.
41. Siragy H.M., Felder R.A., Howell N.L., Chevalier R.L., Peach M.J., Carey R.M. Evidence that intrarenal dopamine acts as a paracrine substance at the renal tubule. Am. J. Physiol. 257:1989;F469-F477.
42. + exchanger (NHE3): resistance to amiloride and inhibition by protein kinase C. Proc. Natl. Acad. Sci. U. S. A. 90:1993;9110-9114.
43. Tsuganezawa H., Sato S., Yamaji Y., Preisig P.A., Moe O.W., Alpern R.J. Role of c-SRC and ERK in acid-induced activation of NHE3. Kidney Int. 62:2002;41-50.
44. van Veldhuisen D.J., Girbes A.R., de Graeff P.A., Lie K.I. Effects of dopaminergic agents on cardiac and renal function in normal man and in patients with congestive heart failure. Int. J. Cardiol. 37:1992;293-300.
45. 1-like dopamine receptor activation and natriuresis by nitrocatechol COMT inhibitors. Kidney Int. 59:2001;1683-1694.
46. West R.E. Jr., Moss J., Vaughan M., Liu T., Liu T.Y. Pertussis toxin-catalyzed ADP-ribosylation of transducin. Cysteine 347 is the ADP-ribose acceptor site. J. Biol. Chem. 260:1985;14428-14430.
47. Wiederkehr M.R., Zhao H., Moe O.W. Acute regulation of Na/H exchanger NHE3 activity by protein kinase C: role of NHE3 phosphorylation. Am. J. Physiol. 276:1999;C1205-C1217.
48. Wiederkehr M.R., Di Sole F., Collazo R., Quinones H., Fan L., Murer H., Helmle-Kolb C., Moe O.W. Characterization of acute inhibition of Na/H exchanger NHE-3 by dopamine in opossum kidney cells. Kidney Int. 59:2001;197-209.
49. 1A receptor regulation of phospholipase C isoform. J. Biol. Chem. 271:1996;19503-19508.
50. Zhao H., Wiederkehr M.R., Fan L., Collazo R.L., Crowder L.A., Moe O.W. Acute inhibition of Na/H exchanger NHE-3 by cAMP. Role of protein kinase a and NHE-3 phosphoserines 552 and 605. J. Biol. Chem. 274:1999;3978-3987.