Oral administration of diphenylarsinic acid, a degradation product of chemical warfare agents, induces oxidative and nitrosative stress in cerebellar Purkinje cells

Life Sciences

Volumn 81, Issue 21-22, 2007, Pages 1518-1525

  Kato, Koichi ^a   Mizoi, Mutsumi ^a   An, Yan ^b   Nakano, Masayuki ^c   Wanibuchi, Hideki ^d   Endo, Ginji ^d   Endo, Yoko ^e   Hoshino, Mikio ^f   Okada, Shoji ^g   Yamanaka, Kenzo ^a  

^a NIHON UNIVERSITY   (Japan)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c NATIONAL HOSPITAL ORGANIZATION CHIBA MEDICAL CENTER   (Japan)

^d OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e TOKYO ROSAI HOSPITAL   (Japan)

^f INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^g UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

3 Nitrotyrosine; Cerebellar symptom; Diphenylarsinic acid; Nitrosative stress; Oxidative stress; Purkinje cells

Indexed keywords

3 NITROTYROSINE; ARSENIC; ARSENOSOBENZENE; CHEMICAL WARFARE AGENT; DIPHENYLARSINIC ACID; MALONALDEHYDE; PEROXYNITRITE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CEREBELLUM DISEASE; CONTROLLED STUDY; FEMALE; MALE; MOUSE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PURKINJE CELL;

ANIMALS; ARSENICALS; BLOTTING, WESTERN; CEREBELLAR DISEASES; CEREBELLUM; CHEMICAL WARFARE AGENTS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GLUTATHIONE PEROXIDASE; IMMUNOHISTOCHEMISTRY; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED ICR; NADP; NEUROTOXICITY SYNDROMES; NITROGEN; OXIDATIVE STRESS; PURKINJE CELLS; REACTIVE OXYGEN SPECIES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

MUS;

EID: 35848929498     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.09.030     Document Type: Article

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