Variegin, a novel fast and tight binding thrombin inhibitor from the tropical bont tick

Journal of Biological Chemistry

Volumn 282, Issue 40, 2007, Pages 29101-29113

  Cho, Yeow Koh ^a   Kazimirova, Maria ^b   Trimnell, Adama ^c   Takac, Peter ^b   Labuda, Milan ^b   Nuttall, Patricia A ^d   Kini, R Manjunatha ^a,e  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

^c SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d CENTRE FOR ECOLOGY AND HYDROLOGY   (United Kingdom)

^e VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMBLYOMMA VARIEGATUM; ANTIHEMOSTATIC MOLECULES; BINDING KINETICS; SALIVARY GLAND;

BINDING SITES; BLOOD; SYNTHESIS (CHEMICAL);

LIVING SYSTEMS STUDIES;

ALANYLPROLYLPROLYLPHENYLALANYLASPARTYLPHENYLALANYLGLUTAMYLALANYL ISOLEUCYLPROLYLGLUTAMYLGLUTAMYLTYROSYLLEUCYLASPARTYLASPARTYLGLUTAMYLSERINE; GLUTAMYLPROLYLLYSYLMETHIONYLHISTIDYLLYSYLTHREONYLALANYLPROLYLPROLYL PHENYLALANYLASPARTYLPHENYLALANYLGLUTAMYLALANYLISOLEUCYLPROLYLGLUTAMYL GLUTAMYLTYROSYLLEUCYLASPARTYLASPARTYLGLUTAMYLSERINE; SERYLASPARTYLGLUTAMINYLGLYCYLASPARTYLVALYLALANYLGLUTAMYLPROLYLLYSYL METHIONYLHISTIDYLLYSYLTHREONYLALANYLPROLYLPROLYLPHENYLALANYLASPARTYLPHENYL ALANYLGLUTAMYLALANYLISOLEUCYLPROLYLGLUTAMYLGLUTAMYLTYROSYLLEUCYLASPARTYL ASPARTYLGLUTAMYLSERINE; THROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG; VARIEGIN;

AMBLYOMMA; AMBLYOMMA VARIEGATUM; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONTROLLED STUDY; DRUG BINDING SITE; DRUG ISOLATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; SALIVARY GLAND; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CIRCULAR DICHROISM; FEMALE; HUMANS; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; SALIVARY GLANDS; SALIVARY PROTEINS; SERINE; THROMBIN; TICKS;

AMBLYOMMA HEBRAEUM; AMBLYOMMA VARIEGATUM; IXODIDA;

EID: 35748980268     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705600200     Document Type: Article

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