A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation

Neuroscience Letters

Volumn 428, Issue 2-3, 2007, Pages 103-108

  Tanahashi, Hiroshi ^a   Tabira, Takeshi ^b  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Alternative splicing; Alzheimer's disease; BACE; mRNA surveillance; Nonsense mediated mRNA decay; Proteasome dependent degradation

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE; IODINE;

AGED; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

AGED; AGED, 80 AND OVER; ALTERNATIVE SPLICING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BINDING SITES; BRAIN; CELL LINE; CELL LINE, TUMOR; CODON, NONSENSE; CONSERVED SEQUENCE; ENZYME ACTIVATION; FEMALE; HUMANS; ISOENZYMES; MALE; MIDDLE AGED; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; RNA STABILITY; RNA, MESSENGER; STRESS;

EID: 35748972942     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.09.033     Document Type: Article

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