Bone healing process in critical-sized defects by rhBMP-2 using poloxamer gel and collagen sponge as carriers

Micron

Volumn 39, Issue 1, 2008, Pages 17-24

  Issa, João Paulo Mardegan ^a   Nascimento, Cássio do ^a   Iyomasa, Mamie Mizusaki ^a   Siéssere, Selma ^a   Regalo, Simone Cecílio Hallak ^a   Defino, Helton Luiz Aparecido ^a   Sebald, Walter ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Bone; Bone morphogenetic protein; Collagen; Histology; Poloxamer

Indexed keywords

BONE; COLLAGEN; GELS; HISTOLOGY; SOLUTIONS; STATISTICAL METHODS;

BONE MORPHOGENETIC PROTEINS; MORPHOGENETIC PROTEINS; POLOXAMERS;

DEFECTS;

ANIMALIA; RATTUS NORVEGICUS;

EID: 35748963548     PISSN: 09684328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micron.2007.08.008     Document Type: Article

References (52)

1. Arosarena O.A., and Collins W.L. Bone regeneration in the rat mandible with bone morphogenetic protein-2: a comparison of two carriers. Otolaryngol. Head Neck Surg. 132 (2005) 592-597
2. Becerra J., Andrades J.A., Santamaria J.A., Cifuentes M., and Guerado E. Bone regeneration, cell therapy and tissue engineering. Med. Clin. 116 (2001) 23-34
3. Bohorquez M., Kock C., Tryastad T., and Pandit N. A study of the temperature-dependent micellization of Pluronic F-127. J. Colloid Interf. Sci. 216 (1999) 34-40
4. Bolander M.E., and Balian G. The use of demineralized bone matrix in the repair of segmental defects. Augmentation with extracted matrix proteins and a comparison with autologous grafts. J. Bone Joint Surg. Am. 68 (1986) 1264-1274
5. Burg K.J.L., Porter S., and Kellam J.F. Biomaterial developments for bone tissue engineering. Biomaterials 21 (2000) 2347-2359
6. Cheng H., Jiang W., Phillips F.M., Haydon R.C., Peng Y., Zhou L., Lu H.H., An N., Breyer B., Vanichakarn P., Szatkowski J.P., Park J.Y., and He T.C. Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J. Bone Joint Surg. Am. 85 (2003) 1544-1552
7. Clokie C.M., and Urist M.R. Bone morphogenetic protein excipients: comparative observations on poloxamer. Plast. Reconstr. Surg. 105 (2000) 628-637
8. Desilets C.P., Marden L.J., Patterson A.L., and Hollinger J.O. Development of synthetic bone-repair materials for craniofacial reconstruction. J. Craniofac. Surg. 1 (1990) 150-153
9. Ducheyne P., el-Ghannam A., and Shapiro I. Effect of bioactive glass templates on osteoblast proliferation and in vitro synthesis of bone-like tissue. J. Cell. Biochem. 56 (1994) 162-167
10. Ducy P., and Karsenty G. The family of bone morphogenetic proteins. Kidney Int. 57 (2000) 2207-2214
11. Friess W., Uludag H., Foskett S., Biron R., and Sargeant C. Characterization of absorbable collagen sponges as rhBMP-2 carriers. Int. J. Pharm. 187 (1999) 91-99
12. Geiger M., Li R.H., and Friess W. Collagen sponges for bone regeneration with rhBMP-2. Adv. Drug Deliv. Rev. 55 (2003) 1613-1629
13. Giannobile W.V., Ryan S., Shih M.S., Su D.L., Kaplan P.L., and Chan T.C.K. Recombinant human osteogenic protein-1 (OP-1) stimulates periodontal wound healing in Class III furcation defects. J. Periodontol. 69 (1998) 129-137
14. Hollinger J.O., and Leong K. Poly(a-hydroxy acids): carriers for bone morphogenetic proteins. Biomaterials 17 (1996) 187-194
15. Hollinger J., Schmitt J.M., Buck D.C., Shannon R., Joh S.P., Zegzula H.D., and Wozney J. Recombinant human bone morphogenetic protein-2 and collagen for bone regeneration. J. Biomed. Mater. Res. 43 (1998) 356-364
16. Inoda H., Yamamoto G., and Hattori T. Histological investigation of osteoinductive properties of rhBMP-2 in a rat calvarial bone defect model. J. Craniomaxillofac. Surg. 32 (2004) 365-369
17. Kato M., Toyoda H., Namikawa T., Hoshino M., Terai H., Miyamoto S., and Takaoka K. Optimized use of a biodegradable polymer as a carrier material for the local delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2). Biomaterials 27 (2006) 2035-2041
18. Kirker-Head C.A. Potential applications and delivery strategies for bone morphogenetic proteins. Adv. Drug Deliv. Rev. 43 (2000) 65-92
19. Kugimiya F., Ohba S., Nakamura K., Kawaguchi H., and Chung U.I. Physiological role of bone morphogenetic proteins in osteogenesis. J. Bone Miner. Metab. 24 (2006) 95-99
20. Lee S.C., Shea M., Battle M.A., et al. Healing of large segmental defects in rat femurs is aided by rhBMP-2 in PLGA matrix. J. Biomed. Mater. Res. 28 (1994) 1149-1156
21. Lee M.B. Bone morphogenetic proteins: background and implications for oral reconstruction. A review. J. Clin. Periodontol. 24 (1997) 355-365
22. Li R.H., and Wozney J.M. Delivering on the promise of bone morphogenetic proteins. Trends Biotechnol. 19 (2001) 255-265
23. Li R.H., Bouxsein M.L., Blake C.A., D'Augusta D., Kim H., Li X.J., Wozney J.M., and Seeherman H.J. rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model. J. Orthopaed. Res. 21 (2003) 997-1004
24. Li W.J., Tuli R., Okafor C., Derfoul A., Danielson K.G., Hall D.J., and Tuan R.S. A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells. Biomaterials 26 (2005) 599-609
25. Lucas P.A., Laurencin C., Syftestad G.T., Domb A., Goldberg V.M., Caplan A.I., and Langer R. Ectopic induction of cartilage and bone by water-soluble proteins from bovine bone using a polyanhydride delivery vehicle. J. Biomed. Mater. Res. 24 (1990) 901-911
26. Miller E.J., and Rhodes R.K. Preparation and characterization of the different types of collagen. Methods Enzymol. 82 Pt A (1982) 33-64
27. Moore T., Croy S., Mallapragada S., and Pandit N. Experimental investigation and mathematical modeling of Pluronic F-127 gel dissolution: drug release in stirred system. J. Control. Release 67 (2000) 191-202
28. Ohgushi H., Dohi Y., Tamai S., and Tabata S. Osteogenic differentiation of marrow stromal stem cells in porous hydroxyapatite ceramics. J. Biomed. Mater. Res. 27 (1993) 1401-1407
29. Paavola A., Kilpelaine I., Yliruusi J., and Rosenberg P. Controlled release injectable liposomal gel of ibuprofen for epidural analgesia. Int. J. Pharm. 199 (2000) 85-93
30. Park H., and Park K. Biocompatibility issues of implantable drug delivery. Pharm. Res. 13 (1996) 1770-1776
31. Pluhar G., Manley P.A., Heiner J.P.R.V., Seeherman Jr. H.J., and Markel M.D. The effect of recombinant human bone morphogenetic protein-2 on femoral reconstruction with an intercalary allograft in a dog model. J. Orthopaed. Res. 19 (1999) 308-317
32. Poynton A.R., and Lane J.M. Safety profile for the clinical use of bone morphogenetic proteins in the spine. Spine 27 16 Suppl. 1 (2002) 40-48
33. Reddi A.H. BMPs: from bone morphogenetic proteins to body morphogenetic proteins. Cytokine Growth Factor Rev. 16 (2005) 249-250
34. Renier M.L., and Kohn D.H. Development and characterization of a biodegradable polyphosphate. J. Biomed. Mater. Res. 34 (1997) 95-104
35. Ripamonti U., and Reddi A.H. Growth and morphogenetic factors in bone induction: role of osteogenin and related bone morphogenetic proteins in craniofacial and periodontal bone repair. Crit. Rev. Oral. Biol. Med. 3 (1992) 1-14
36. Schenk R.K., Buser D., Hardwock W.R., and Dahlin C. Healing pattern of bone regeneration in membrane-protected defects: a histological study in the canine mandible. Int. J. Oral. Maxillofac. Implants 9 (1994) 13-29
37. Schilephake H. Bone growth factors in maxillofacial skeletal reconstruction. Int. J. Oral. Maxillofac. Surg. 31 (2002) 469-484
38. Seeherman H.J., Bouxsein M., Kim H., Li R., Li X.J., Aiolova M., and Wozney J.M. Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model. J. Bone Joint Surg. Am. 86 (2004) 1961-1972
39. Seeherman H., and Wozney J.M. Delivery of bone morphogenetic proteins for orthopedic tissue regeneration. Cytokine Growth Factor Rev. 16 (2005) 329-345
40. Simon Z., Deporter D.A., Pilliar R.M., and Clokie C.M. Heterotopic bone formation around sintered porous-surfaced Ti-6Al-4V implants coated with native bone morphogenetic proteins. Implant Dent. 15 (2006) 265-274
41. Svensson A., Nicklasson E., Harrah T., Panilaitis B., Kaplan D.L., Brittberg M., and Gatenholm P. Bacterial cellulose as a potential scaffold for tissue engineering of cartilage. Biomaterials 26 (2005) 419-431
42. Toriumi D.M., Kotler H.S., Luxenberg D.P., Holtrop M.E., and Wang E.A. Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation. Arch. Otolaryngol. Head Neck Surg. 117 (1991) 1101-1112
43. Ueno T., Mizukawa N., and Sugahara T. Experimental study of bone formation from autogenous periosteal graft following insulin-like growth factor I administration. J. Craniomaxillofac. Surg. 27 (1999) 308-313
44. Urist M. Bone: formation by autoinduction. Science 150 (1965) 893-899
45. Veyries M.L., Couarraze G., Geiger S., Agnely F., Massias L., Kunzli B., Faurisson F., and Rouveix B. Controlled release of vancomycin from Poloxamer 407 gels. Int. J. Pharm. 192 (1999) 183-193
46. Wang E.A., Rosen V., D'Alessandro J.S., Bauduy M., Cordes P., Harada T., Israel D.I., Hewick R.M., Kerns K.M., LaPan P., Luxenberg D.P., Mc Quaid D., Moutsatsos I.K., Nove J., and Wozney J.M. Recombinant human bone morphogenetic protein induces bone formation. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 2220-2224
47. Weibel E.R., Kistler G.S., and Scherle W.F. Practical stereological methods for morphometric cytology. J. Cell Biol. 30 (1966) 23-38
48. Wikesjo U.M., Guglielmoni P., Promsudthi A., Cho K.S., Trombelli L., Selvig K.A., Jin L., and Wozney J.M. Periodontal repair in dogs: effect of rhBMP-2 concentration on regeneration of alveolar bone and periodontal attachment. J. Clin. Periodontol. 26 (1999) 392-400
49. Winn S.R., Uludag H., and Hollinger J.O. Carrier systems for bone morphogenetic proteins. Clin. Orthop. Relat. Res. 367 Suppl. (1999) 95-106
50. Wozney J.M., Rosen V., Celeste A.J., Mitsock L.M., Whitters M.J., Kriz R.W., Hewick R.M., and Wang E.A. Novel regulators of bone formation: molecular clones and activities. Science 242 (1988) 1528-1534
51. Zabka A., Pluhar G.E., Edwards R.B., Manley P.A., Hayashi K., Heiner J.P., Kalscheur V.L., and Seeherman H.J. Histomorphometric description of allograft bone remodeling and union in a canine segmental femoral defect model: a comparison of rhBMP-2, cancellous bone graft, and absorbable collagen sponge. J. Orthopaed. Res. 19 (2001) 318-327
52. Zhang J.X., Li X.J., Qiu L.Y., Li X.H., Yan M.Q., Yi Jin., and Zhu K.J. Indomethacin-loaded polymeric nanocarriers based on amphiphilic polyphosphazenes with poly (N-isopropylacrylamide) and ethyl tryptophan as side groups: preparation, in vitro and in vivo evaluation. J. Control. Release 116 (2006) 322-329