Optimized use of a biodegradable polymer as a carrier material for the local delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2)

Biomaterials

Volumn 27, Issue 9, 2006, Pages 2035-2041

  Kato, Minori ^a   Toyoda, Hiromitsu ^a   Namikawa, Takashi ^a   Hoshino, Masatoshi ^a   Terai, Hidetomi ^a   Miyamoto, Shimpei ^a   Takaoka, Kunio ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Biodegradation; BMP (bone morphogenetic proteins); Bone; Drug delivery

Indexed keywords

BIODEGRADATION; BONE; DATA ACQUISITION; DRUG DOSAGE; POLYETHYLENE GLYCOLS; PROTEINS;

BONE MORPHOGENETIC PROTEINS (BMP); L-LACTIC ACID; OSTEOINDUCTIVE PROTEIN; P-DIOXANONE;

BLOCK COPOLYMERS;

COPOLYMER; DRUG CARRIER; POLY(LACTIC ACID CO 4 DIOXANONE CO ETHYLENE GLYCOL); POLYGLACTIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY OSSICLE; BIODEGRADATION; BONE MINERAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DELIVERY SYSTEM; IMPLANT; MALE; MOUSE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL;

ANIMALS; BIODEGRADATION, ENVIRONMENTAL; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG IMPLANTS; HUMANS; LACTATES; MALE; MICE; MICE, INBRED ICR; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 28744441817     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2005.10.007     Document Type: Article

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