Bifunctional amine-tethered ruthenium(II) arene complexes form monofunctional adducts on DNA

Inorganic Chemistry

Volumn 46, Issue 21, 2007, Pages 8950-8962

  Melchart, Michael ^a   Habtemariam, Abraha ^b   Novakova, Olga ^c   Moggach, Stephen A ^a   Fabbiani, Francesca P A ^a   Parsons, Simon ^a   Brabec, Viktor ^c   Sadler, Peter J ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

^c INSTITUTE OF BIOPHYSICS   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DNA; DNA DIRECTED RNA POLYMERASE; RUTHENIUM DERIVATIVE;

ANIMAL; ARTICLE; CATTLE; CHEMICAL MODEL; CHEMISTRY; CONFORMATION; DNA ADDUCT; DNA SUPERCOILING; FEMALE; HUMAN; IC 50; METABOLISM; METHODOLOGY; OVARY TUMOR; PH; THYMUS;

ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CHEMISTRY; CISPLATIN; DNA; DNA ADDUCTS; DNA, SUPERHELICAL; DNA-DIRECTED RNA POLYMERASES; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR CONFORMATION; OVARIAN NEOPLASMS; RUTHENIUM COMPOUNDS; THYMUS GLAND;

EID: 35648996964     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic700799w     Document Type: Article

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