Cardiopulmonary responses of Wistar Kyoto, spontaneously hypertensive, and stroke-prone spontaneously hypertensive rats to particulate matter (PM) exposure

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 70, Issue 22, 2007, Pages 1912-1922

  Wallenborn, J Grace ^a   Schladweiler, Mette C ^b   Nyska, Abraham ^c,d   Johnson, Jo Anne ^e   Thomas, Ronald ^b   Jaskot, Richard H ^b   Richards, Judy H ^b   Ledbetter, Allen D ^b   Kodavanti, Urmila P ^b  

^a IL   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

^d Toxicologic Pathology ^*  (Israel)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLGLUCOSAMINIDASE; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; ISOCITRATE DEHYDROGENASE; LACTATE DEHYDROGENASE; PROTEIN; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOPULMONARY HEMODYNAMICS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; ENZYME ACTIVITY; GENETICS; LUNG INJURY; LUNG LAVAGE; MALE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER; PNEUMONIA; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ACETYLGLUCOSAMINIDASE; AIR POLLUTANTS; ALBUMINS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; FERRITINS; GAMMA-GLUTAMYLTRANSFERASE; GLUTAMATE DEHYDROGENASE; INFLAMMATION; ISOCITRATE DEHYDROGENASE; L-LACTATE DEHYDROGENASE; LUNG; MALE; MITOCHONDRIA; MYOCARDIUM; OXIDATIVE STRESS; PARTICULATE MATTER; POWER PLANTS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; STROKE; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 35648982469     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390701551233     Document Type: Article

References (59)

1. Abrescia, P., and Golino, P. 2005. Free radicals and antioxidants in cardiovascular diseases. Expert Rev. Cardiovasc. Ther. 3:159-171.
2. Adamson, I. Y., Prieditis, H., Hedgecock, C., and Vincent, R. 2000. Zinc is the toxic factor in the lung response to an atmospheric particulate sample. Toxicol. Appl. Pharmacol. 166:111-119.
3. American Heart Association. 2004. Heart disease and stroke statistics - 2005 Update. Dallas, TX: American Heart Association.
4. Armengou, A., and Davalos, A. 2002. A review of the state of research into the role of iron in stroke. J. Nutr. Health Aging 6:207-208.
5. Benard, G., Faustin, B., Passerieux, E., Galinier, A., Rocher, C., Bellance, N., Delage, J. P., Casteilla, L., Letellier, T., and Rossignol, R. 2006. Physiological diversity of mitochondrial oxidative phosphorylation. Am. J. Physiol. Cell Physiol. 291:C1172-1182.
6. Benderdour, M., Charron, G., Comte, B., Ayoub, R., Beaudry, D., Foisy, S., Deblois, D., and des Rosiers, C. 2004. Decreased cardiac mitochondrial NADP+-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development. Am. J. Physiol. Heart Circ. Physiol. 287:H2122-H2131.
7. Carll, A. P., Rowan, W. H., Wallenborn, J., Winsett, D. W., Schladweiler, M., Wichers, L. B., Costa, D. L., Kodavanti, U. P., and Watkinson, W. P. 2006. Differences in cardiovascular response to pm exposure between spontaneously hypertensive stroke-prone (SHSP) and Wistar Kyoto (WKY) rats. Toxicologist 90:445.
8. Costa, D. L., Lehmann, J. R., Harold, W. M., and Drew, R. T. 1986. Transoral tracheal intubation of rodents using a fiberoptic laryngoscope. Lab. Anim. Sci. 36:256-261.
9. Costa, D. L., Lehmann, J. R., Winsett, D., Richards, J., Ledbetter, A. D., and Dreher, K. L. 2006. Comparative pulmonary toxicological assessment of oil combustion particles following inhalation or instillation exposure. Toxicol. Sci. 91:237-246.
10. de Champlain, J., Wu, R., Girouard, H., Karas, M., El Midaoui, A., Laplante, M. A., and Wu, L. 2004. Oxidative stress in hypertension. Clin. Exp. Hypertens. 26:593-601.
11. Dhanasekaran, A., Kotamraju, S., Kalivendi, S. V., Matsunaga, T., Shang, T., Keszler, A., Joseph, J., and Kalyanaraman, B. 2004. Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. J. Biol. Chem. 279:37575-37587.
12. Donaldson, K., Stone, V., Borm, P. J., Jimenez, L. A., Gilmour, P. S., Schins, R. P., Knaapen, A. M., Rahman, I., Faux, S. P., Brown, D. M., and MacNee W. 2003. Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radical Biol. Med. 34:1369-1382.
13. Dudley, R. W., Khairallah, M., Mohammed, S., Lands, L., Des Rosiers, C., and Petrof, B. J. 2006. Dynamic responses of the glutathione system to acute oxidative stress in dystrophic mouse (mdx) muscles. Am. J. Physiol. Regul. Integr. Comp. Physiol. 291:R704-710.
14. Friedman, J., Peleg, E., Kagan, T., Shnizer, S., and Rosenthal, T. 2003. Oxidative stress in hypertensive, diabetic, and diabetic hypertensive rats. Am. J. Hypertens. 16:1049-1052.
15. Ghio, A. J., Churg, A., Roggli, and V. L. 2004. Ferruginous bodies: Implications in the mechanism of fiber and particle toxicity. Toxicol. Pathol. 32:643-649.
16. Ghio, A. J., and Cohen, M. D. 2005. Disruption of iron homeostasis as a mechanism of biologic effect by ambient air pollution particles. Inhal. Toxicol. 17:709-716.
17. Gilmour, P. S., Nyska, A., Schladweiler, M. C., McGee, J. K., Wallenborn, J. G., Richards, J. H., and Kodavanti, U. P. 2006. Cardiovascular and blood coagulative effects of pulmonary zinc exposure. Toxicol. Appl. Pharmacol. 211:41-52.
18. Gilmour P. S., Schladweiler M. C., Richards J. H., Ledbetter A. D., and Kodavanti U. P. 2004. Hypertensive rats are susceptible to TLR4-mediated signaling following exposure to combustion source particulate matter. Inhal. Toxicol. 16(Suppl.):5-18.
19. Gurgueira, S. A., Lawrence, J., Coull, B., Murthy, G. G., and Gonzalez-Flecha, B. 2002. Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation. Environ. Health Perspect. 110:749-755.
20. Jaskot, R. H., Charlet, E. G., Grose, E. C., Grady, M. A., and Roycroft, J. H. 1983. An automated analysis of glutathione peroxidase, S-transferase, and reductase activity in animal tissue. J. Anal. Toxicol. 7:86-88.
21. Jeffs, B., Clark, J. S., Anderson, N. H., Gratton, J., Brosnan, M. J., Gauguier, D., Reid, J. L., Macrae, I. M., and Dominiczak, A. F. 1997. Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nat. Genet. 16:364-367.
22. Jousilahti, P., Rastenyte, D., Tuomilehto, J., Sarti, C., and Vartiainen, E. 1997. Parental history of cardiovascular disease and risk of stroke. A prospective follow-up of 14371 middle-aged men and women in Finland. Stroke 28:1361-1366.
23. Kato, N., Nabika, T., Liang, Y. Q., Mashimo, T., Inomata, H., Watanabe, T., Yanai, K., Yamori, Y., Yazaki, Y., and Sasazuki, T. 2003. Isolation of a chromosome 1 region affecting blood pressure and vascular disease traits in the stroke-prone rat model. Hypertension 42:1191-1197.
24. Kil, I. S., Huh, T. L., Lee, Y. S., Lee, Y. M., and Park, J. W. 2006a. Regulation of replicative senescence by NADP+-dependent isocitrate dehydrogenase. Free Radical Biol. Med. 40:110-119.
25. Kil, I. S., Shin, S. W., Yeo, H. S., Lee, Y. S., and Park, J. W. 2006b. Mitochondrial NADP+-dependent isocitrate dehydrogenase protects cadmium-induced apoptosis. Mol. Pharmacol. 70:1053-1061.
26. Kochanek, K. D., Murphy, S. L., Anderson, R. N., and Scott, C. 2004. Deaths: Final data for 2002. Natl. Vital Stat. Rep. 53:1-115.
27. Kodavanti, U. P., Costa, D. L., and Bromberg, P. A. 1998a. Rodent models of cardiopulmonary disease: Their potential applicability in studies of air pollutant susceptibility. Environ. Health Perspect. 106(Suppl.):111-130.
28. Kodavanti, U. P., Hauser, R., Christiani, D. C., Meng, Z. H., McGee, J., Ledbetter, A., Richards, J., and Costa, D. L. 1998b. Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals. Toxicol. Sci. 43:204-212.
29. Kodavanti, U. P., Jaskot, R. H., Costa, D. L., and Dreher, K. D. 1997. Pulmonary proinflammatory gene induction following acute exposure to residual oil fly ash: Roles of particle-associated metals. Inhal. Toxicol. 9:679-701.
30. Kodavanti, U. P., Schladweiler, M. C., Ledbetter, A. D., Hauser, R., Christiani, D. C., McGee, J., Richards, J. R., and Costa, D. L. 2002. Temporal association between pulmonary and systemic effects of particulate matter in healthy and cardiovascular compromised rats. J. Toxicol. Environ. Health A 65:1545-1569.
31. Kodavanti, U. P., Schladweiler, M. C., Ledbetter, A. D., Watkinson, W. P., Campen, M. J., Winsett, D. W., Richards, J. R., Crissman, K. M., Hatch, G. E., and Costa, D. L. 2000. The spontaneously hypertensive rat as a model of human cardiovascular disease: Evidence of exacerbated cardiopulmonary injury and oxidative stress from inhaled emission particulate matter. Toxicol. Appl. Pharmacol. 164:250-263.
32. Kowaltowski, A. J., and Vercesi, A. E. 1999. Mitochondrial damage induced by conditions of oxidative stress. Free Radical Biol. Med. 26:463-471.
33. Lacy, F., O'Connor, D. T., and Schmid-Schonbein, G. W. 1998. Plasma hydrogen peroxide production in hypertensive and normotensive subjects at genetic risk of hypertension. J. Hypertens. 16:291-303.
34. Maianski, N. A., Geissler, J., Srinivasula, S. M., Alnemri, E. S., Roos, D., and Kuijpers, T. W., 2004. Functional characterization of mitochondria in neutrophils: A role restricted to apoptosis. Cell Death Differ. 11:143-153.
35. Matchar, D. B., and Duncan, P. W. 1994. Cost of stroke. Stroke Clin. Updates 5:9-12.
36. McBride, M. W., Brosnan, M. J., Mathers, J., McLellan, L. I., Miller, W. H., Graham, D., Hanlon, N., Hamilton, C. A., Polke, J. M., Lee, W. K., and Dominiczak, A. F. 2005. Reduction of Gstm1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress. Hypertension 45:786-792.
37. Morris, R. D., Naumova, E. N., and Munasinghe, R. L. 1995. Ambient air pollution and hospitalization for congestive heart failure among elderly people in seven large US cities. Am. J. Public Health 85:1361-1365.
38. Nabika, T., Cui, Z., and Masuda, J. 2004. The stroke-prone spontaneously hypertensive rat: How good is it as a model for cerebrovascular diseases? Cell Mol. Neurobiol. 24:639-646.
39. Napier, I., Ponka, P., and Richardson, D. R. 2005. Iron trafficking in the mitochondrion: Novel pathways revealed by disease. Blood 105:1867-1874.
40. Negishi, H., Ikeda, K., Sagara, M., Sawamura, M., and Yamori, Y. 1999. Increased oxidative DNA damage in stroke-prone spontaneously hypertensive rats. Clin. Exp. Pharmacol. Physiol. 26:482-484.
41. Nel, A. 2005. Atmosphere. Air pollution-related illness: Effects of particles. Science 308:804-806.
42. O'Neill, M. S., Veves, A., Zanobetti, A., Sarnat, J. A., Gold, D. R., Economides, P. A., Horton, E. S., and Schwartz, J. 2005. Diabetes enhances vulnerability to particulate air pollution-associated impairment in vascular reactivity and endothelial function. Circulation 111:2913-2920.
43. Oury, T. D., Schaefer, L. M., Fattman, C. L., Choi, A., Weck, K. E., and Watkins, S. C. 2002. Depletion of pulmonary EC-SOD after exposure to hyperoxia. Am. J. Physiol. Lung Cell Mol. Physiol. 283:L777-L784.
44. Pope, C. A., Burnett, R. T., Thurston, G. D., Thun, M. J., Calle, E. E., Krewski, D., and Godleski, J. J. 2004. Cardiovascular mortality and long-term exposure to particulate air pollution: Epidemiological evidence of general pathophysiological pathways of disease. Circulation 109:71-77.
45. Roberts, E. S., Richards, J. H., Jaskot, R., and Dreher, K. L. 2003. Oxidative stress mediates air pollution particle-induced acute lung injury and molecular pathology. Inhal. Toxicol. 15:1327-1346.
46. Russo, C., Olivieri, O., Girelli, D., Faccini, G., Zenari, M. L., Lombardi, S., and Corrocher, R. 1998. Anti-oxidant status and lipid peroxidation in patients with essential hypertension. J. Hypertens. 16:1267-1271.
47. Scandalios, J. G. 2005. Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses. Braz. J. Med. Biol. Res. 38:995-1014.
48. Sun, Q., Wang, A., Jin, X., Natanzon, A., Duquaine, D., Brook, R. D., Aquinaldo, J. G., Fayad, Z. A., Fuster, V., Lippmann, M., Chen, L. C., and Rajagopalan, S. 2005. Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal model. J. Am. Med. Assoc. 294:3003-3010.
49. Sunyer, J., Schwartz, J., Tobias, A., Macfarlane, D., Garcia, J., and Anto, J. M. 2000. Patients with chronic obstructive pulmonary disease are at increased risk of death associated with urban particle air pollution: A case-crossover analysis. Am. J. Epidemiol. 151:50-56.
50. Tokoro, T., Ito, H., and Suzuki, T. 1996. Alterations in mitochondrial DNA and enzyme activities in hypertrophied myocardium of stroke-prone SHRs. Clin. Exp. Hypertens. 18:595-606.
51. Touyz, R. M. 2000. Oxidative stress and vascular damage in hypertension. Curr. Hypertens. Rep. 2:98-105.
52. Tretter, L., and Adam-Vizi, V. 2005. Alpha-ketoglutarate dehydrogenase: A target and generator of oxidative stress. Philos. Trans. R. Soc. Lond. Biol. Sci. 360:2335-2345.
53. Wang, X., Wu, Y., Stonehuerner, J. G., Dailey, L. A., Richards, J. D., Jaspers, I., Piantadosi, C. A., and Ghio, A. J. 2006. Oxidant generation promotes iron sequestration in BEAS-2B cells exposed to asbestos. Am. J. Respir. Cell Mol. Biol. 34:286-292.
54. Wellenius, G. A., Saldiva, P. H., Batalha, J. R., Krishna Murthy, G. G., Coull, B. A., Verrier, R. L., and Godleski, J. J. 2002. Electrocardiographic changes during exposure to residual oil fly ash (ROFA) particles in a rat model of myocardial infarction. Toxicol. Sci. 66:327-335.
55. Wellenius, G. A., Schwartz, J., and Mittleman, M. A. 2005. Air pollution and hospital admissions for ischemic and hemorrhagic stroke among medicare beneficiaries. Stroke36:2549-2553.
56. Wichers, L. B., Ledbetter, A. D., McGee, J. K., Kellogg, R. B., Rowan, W. H., Nolan, J. P., Costa, D. L., and Watkinson, W. P. 2006. A method for exposing rodents to resuspended particles using whole-body plethysmography. Part. Fibre Toxicol. 3:12.
57. Wichers, L. B., Nolan, J. P., Winsett, D. W., Ledbetter, A. D., Kodavanti, U. P., Schladweiler, M. C., Costa, D. L., and Watkinson, W. P. 2004a. Effects of instilled combustion-derived particles in spontaneously hypertensive rats. Part I: Cardiovascular responses. Inhal. Toxicol. 16:391-405.
58. Wichers, L. B., Nolan, J. P., Winsett, D. W., Ledbetter, A. D., Kodavanti, U. P., Schladweiler, M. C., Costa, D. L., and Watkinson, W. P. 2004b. Effects of instilled combustion-derived particles in spontaneously hypertensive rats. Part II: Pulmonary responses. Inhal. Toxicol. 16:407-419.
59. Yoshioka, A., and Kishino, Y. 1989. Vascular changes involved in pulmonary hemorrhage of stroke-prone spontaneously hypertensive rats. Tokushima J. Exp. Med. 36:1-10.