Retention of intravenously infused [13C]bicarbonate is transiently increased during recovery from hard exercise

Journal of Applied Physiology

Volumn 103, Issue 5, 2007, Pages 1604-1612

  Henderson, Gregory C ^a   Fattor, Jill A ^a   Horning, Michael A ^a   Faghihnia, Nastaran ^a   Luke Zeitoun, Mona ^a   Brooks, George A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Correction factor; Exertion; Fatty acid oxidation; Glucose oxidation; Leucine oxidation; NaHCO3; Physical activity; Postexercise; Prior exercise

Indexed keywords

BICARBONATE C 13; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BREATH ANALYSIS; CARBON DIOXIDE EXCRETION; CONTROLLED STUDY; ENERGY METABOLISM; EXERCISE INTENSITY; FEMALE; FLUID RETENTION; HUMAN; HUMAN EXPERIMENT; HYPERCAPNIA; LUNG GAS EXCHANGE; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SEX DIFFERENCE; SPIROMETRY;

ADULT; CARBON DIOXIDE; CARBON ISOTOPES; ENERGY METABOLISM; EXERCISE; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MODELS, BIOLOGICAL; MUSCLE, SKELETAL; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PHYSICAL ENDURANCE; PULMONARY VENTILATION; RECOVERY OF FUNCTION; SODIUM BICARBONATE; TIME FACTORS;

EID: 35648934486     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00309.2007     Document Type: Article

References (49)

1. 13C]bicarbonate washout kinetics. Am J Physiol Regul Integr Comp Physiol 259: R163-R171, 1990.
2. Beaufrere B, Horber FF, Schwenk WF, Marsh HM, Matthew D, Gerich JE, Haymond MW. Glucocorticosteroids increase leucine oxidation and impair leucine balance in humans. Am J Physiol Endocrinol Metab 257: E712-E721, 1989.
3. Broeder CE, Brenner M, Hofman Z, Paijmans IJM, Thomas EL, Wilmore JH. The metabolic consequences of low and moderate intensity exercise with or without feeding in lean and borderline obese males. Int J Obes 15: 95-104, 1991.
4. Brooks GA, Brauner KE, Cassens RG. Glycogen synthesis and metabolism of lactic acid after exercise. Am J Physiol 224: 1162-1166, 1973.
5. Brooks GA, Donovan CM. Effects of endurance training on glucose kinetics during exercise. Am J Physiol Endocrinol Metab 244: E505-E512, 1983.
6. Brooks GA, Gaesser GA. End points of lactate and glucose metabolism after exhausting exercise. J Appl Physiol Respir Environ Exercise Physiol 49: 1057-1069, 1980.
7. 2 production during exercise before and after endurance training. J Appl Physiol 75: 70-75, 1993.
8. Devlin JT, Brodsky I, Scrimgeour A, Fuller S, Bier DM. Amino acid metabolism after intense exercise. Am J Physiol Endocrinol Metab 258: E249-E255, 1990.
9. 13C-labelled pasta meals following rest or exercise in man. Br J Nutr 85: 671-680, 2001.
10. Friedlander AL, Braun B, Pollack M, Macdonald JR, Fulco CS, Muza SR, Rock PB, Henderson GC, Horning MA, Brooks GA, Hoffman AR, Cymerman A. Three weeks of caloric restriction alters protein metabolism in normal-weight, young men. Am J Physiol Endocrinol Metab 289: E446-E455, 2005.
11. Garlick PJ, McNurlan MA, McHardy KC, Calder AG, Milne E, Fearns LM, Broom J. Rates of nutrient utilization in man measured by combined respiratory gas analysis and stable isotopic labeling: effect of food intake. Hum Nutr Clin Nutr 41C: 177-191, 1987.
12. 14C]Bicarbonate fixation into glucose and other metabolites in the liver of the starved rat under halothane anaesthesia. Biochem J 227: 851-867, 1985.
13. 3 infused by gut and vein: effect of feeding. Am J Physiol Endocrinol Metab 257: E426-E438, 1989.
14. IOM. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. Washington, DC: National Academies, 2002.
15. Issekutz B Jr, Paul P, Miller HI. Oxidation of plasma FFA in lean and obese humans. Metabolism 17: 62-73, 1968.
16. Jackson AS, Pollock ML. Generalized equations for prediction body density of men. Br J Nutr 40: 497-504, 1978.
17. Jackson AS, Pollock ML, Ward A. Generalized equations for prediction body density of women. Med Sci Sports Exerc 12: 175-181, 1980.
18. Jacobs KA, Casazza GA, Suh SH, Horning MA, Brooks GA. Fatty acid reesterification but not oxidation is increased by oral contraceptive use in women. J Appl Physiol 98: 1720-1732, 2005.
19. 31P NMR. Proc Natl Acad Sci USA 97: 6880-6884, 2000.
20. 14C-labelled bicarbonate in the cat. Biochem J 51: 351-357, 1952.
21. Kuo CC, Fattor JA, Henderson GC, Brooks GA. Lipid oxidation in fit young adults during postexercise recovery. J Appl Physiol 99: 349-356, 2005.
22. Lamont LS, McCullough AJ, Kalhan SC. Comparison of leucine kinetics in endurance-trained and sedentary humans. J Appl Physiol 86: 320-325, 1999.
23. Lamont LS, McCullough AJ, Kalhan SC. Gender differences in leucine, but not lysine, kinetics. J Appl Physiol 91: 357-362, 2001.
24. 13C bicarbonate: the effects of exercise and acid base balance. Eur J Clin Invest 24: 818-823, 1994.
25. Lusk G. Animal calorimetry: analysis of the oxidation of mixtures of carbohydrate and fat. J Biol Chem 59: 41-42, 1924.
26. Melanson EL, Sharp TA, Seagle HM, Horton TJ, Donahoo WT, Grunwald GK, Hamilton JT, Hill JO. Effect of exercise intensity on 24-h energy expenditure and nutrient oxidation. J Appl Physiol 92: 1045-1052, 2002.
27. Miller BF, Fattor JA, Jacobs KA, Horning MA, Navazio F, Lindinger MI, Brooks GA. Lactate and glucose interactions during rest and exercise in men: effect of exogenous lactate infusion. J Physiol 544: 963-975, 2002.
28. Mittendorfer B, Sidossis LS, Walser E, Chinkes DL, Wolfe RR. Regional acetate kinetics and oxidation in human volunteers. Am J Physiol Endocrinol Metab 274: E978-E983, 1998.
29. Moehn S, Bertolo RFP, Pencharz PB, Ball RO. Pattern of carbon dioxide production and retention is similar in adult pigs when fed hourly, but not when fed a single meal. BMC Physiol 4: 11, 2004.
30. 3 in unanaesthetized rats. J Physiol 163: 713-728, 1963.
31. 13C] acetate. Metabolism 47: 549-554, 1998.
32. Sahlin K, Alvestrand A, Brandt R, Hultman AE. Intracellular pH and bicarbonate concentration in human muscle during recovery from exercise. J Appl Physiol 45: 474-480, 1978.
33. Saris WHM, Schrauwen P. Substrate oxidation differences between high- and low-intensity exercise are compensated over 24 hours in obese men. Int J Obes 28: 759-765, 2004.
34. 13C]substrate oxidation. Clin Sci (Lond) 98: 587-592, 2000.
35. 14 studies in carbohydrate metabolism. IV. Characteristics of bicarbonate pool system in the rat. Am J Physiol 197: 41-46, 1959.
36. Sidossis LS, Coggan AR, Gastaldelli A, Wolfe RR. A new correction factor for use in tracer estimations of plasma fatty acid oxidation. Am J Physiol Endocrinol Metab 269: E649-E656, 1995.
37. Stringer W, Casaburi R, Wasserman K. Acid-base regulation during exercise and recovery in humans. J Appl Physiol 72: 954-961, 1992.
38. Tarnopolsky MA, Atkinson SA, MacDougall JD, Senor BB, Lemon PWR, Schwarcz H. Whole body leucine metabolism during and after resistance exercise in fed humans. Med Sci Sports Exerc 23: 326-333, 1991.
39. 2 in the perfused rat liver. Biochem J 208: 231-234, 1982.
40. Trimmer JK, Casazza GA, Horning MA, Brooks GA. Autoregulation of glucose production in men with a glycerol load during rest and exercise. Am J Physiol Endocrinol Metab 280: E657-E668, 2001.
41. 3 infusions. Am J Physiol Endocrinol Metab 281: E683-E692, 2001.
42. Van Hall G, Bülow J, Sacchetti M, Mulla NA, Lyngsø D, Simonsen L. Regional fat metabolism in human splanchnic and adipose tissues; the effect of exercise. J Physiol 543: 1033-1046, 2002.
43. Van Hall G, Sacchetti M, Rådegran G, Saltin B. Human skeletal muscle fatty acid and glycerol metabolism during rest, exercise and recovery. J Physiol 543: 1047-1058, 2002.
44. 13C]acetate recovery factor in metabolic research. Eur J Appl Physiol 89: 377-383, 2003.
45. Votruba SB, Atkinson RL, Hirvonen MD, Schoeller DA. Prior exercise increases subsequent utilization of dietary fat. Med Sci Sports Exerc 34: 1757-1765, 2002.
46. Votruba SB, Atkinson RL, Schoeller DA. Prior exercise increases dietary oleate, but not palmitate oxidation. Obes Res 11: 1509-1518, 2003.
47. Votruba SB, Atkinson RL, Schoeller DA. Sustained increase in dietary oleic acid oxidation following morning exercise. Int J Obes 29: 100-107, 2005.
48. Wolfe RR, Wolfe MH, Nadel ER, Shaw JHF. Isotopic determination of amino acid-urea interactions in exercise in humans. J Appl Physiol Respir Environ Exercise Physiol 56: 221-229, 1984.
49. Zuntz N, Schumburg D. Studien zu einer physiologie des marches. Berlin: Verlag von August Hirschwald, 1901.