-
1
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
Coussens L, Yang-Feng TL, Liao YC, et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985;230:1132-9.
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
-
2
-
-
0034766736
-
Biology of HER2 and its importance in breast cancer
-
Yarden Y. Biology of HER2 and its importance in breast cancer. Oncology 2001;61 Suppl 2:1-13.
-
(2001)
Oncology
, vol.61
, Issue.SUPPL. 2
, pp. 1-13
-
-
Yarden, Y.1
-
3
-
-
0035115441
-
Overexpression of HER2/neu in solid tumours: An immunohistochemical survey
-
Koeppen HK, Wright BD, Burt AD, et al. Overexpression of HER2/neu in solid tumours: an immunohistochemical survey. Histopathology 2001;38:96-104.
-
(2001)
Histopathology
, vol.38
, pp. 96-104
-
-
Koeppen, H.K.1
Wright, B.D.2
Burt, A.D.3
-
4
-
-
0034255737
-
HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes
-
Seliger B, Rongcun Y, Atkins D, et al. HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes. Int J Cancer 2000;87:349-59.
-
(2000)
Int J Cancer
, vol.87
, pp. 349-359
-
-
Seliger, B.1
Rongcun, Y.2
Atkins, D.3
-
5
-
-
0034473197
-
HER-2/neu as a therapeutic target in non - small cell lung cancer, prostate cancer, and ovarian cancer
-
discussion 92-100
-
Agus DB, Bunn PA, Jr., Franklin W, Garcia M, Ozols RF. HER-2/neu as a therapeutic target in non - small cell lung cancer, prostate cancer, and ovarian cancer. Semin Oncol 2000;27:53-63; discussion 92-100.
-
(2000)
Semin Oncol
, vol.27
, pp. 53-63
-
-
Agus, D.B.1
Bunn Jr., P.A.2
Franklin, W.3
Garcia, M.4
Ozols, R.F.5
-
6
-
-
0032549036
-
The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: From orphanhood to multiple stromal ligands
-
Tzahar E, Yarden Y. The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: from orphanhood to multiple stromal ligands. Biochim Biophys Acta 1998;1377:M25-37.
-
(1998)
Biochim Biophys Acta
, vol.1377
-
-
Tzahar, E.1
Yarden, Y.2
-
7
-
-
0023663896
-
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
-
Di Fiore PP, Pierce JH, Fleming TP, et al. Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell 1987;51:1063-70.
-
(1987)
Cell
, vol.51
, pp. 1063-1070
-
-
Di Fiore, P.P.1
Pierce, J.H.2
Fleming, T.P.3
-
8
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/ neu oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/ neu oncogene. Science 1987;235:177-82.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
9
-
-
0038456096
-
Immunity to melanoma: Unraveling the relation of tumor immunity and autoimmunity
-
Ramirez-Montagut T, Turk MJ, Wolchok JD, Guevara-Patino JA, Houghton AN. Immunity to melanoma: unraveling the relation of tumor immunity and autoimmunity. Oncogene 2003;22:3180-7.
-
(2003)
Oncogene
, vol.22
, pp. 3180-3187
-
-
Ramirez-Montagut, T.1
Turk, M.J.2
Wolchok, J.D.3
Guevara-Patino, J.A.4
Houghton, A.N.5
-
12
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006;354:567-78.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
13
-
-
0035257549
-
Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials
-
Slamon D, Pegram M. Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials. Semin Oncol 2001;28:13-9.
-
(2001)
Semin Oncol
, vol.28
, pp. 13-19
-
-
Slamon, D.1
Pegram, M.2
-
14
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel CL, Cobleigh MA, Tripathy D, et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:719-26.
-
(2002)
J Clin Oncol
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
-
15
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-92.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
16
-
-
0033754789
-
Pre-existent immunity to the HER-2/neu oncogenic protein in patients with HER-2/neu overexpressing breast and ovarian cancer
-
Disis ML, Knutson KL, Schiffman K, Rinn K, McNeel DG. Pre-existent immunity to the HER-2/neu oncogenic protein in patients with HER-2/neu overexpressing breast and ovarian cancer. Breast Cancer Res Treat 2000;62:245-52.
-
(2000)
Breast Cancer Res Treat
, vol.62
, pp. 245-252
-
-
Disis, M.L.1
Knutson, K.L.2
Schiffman, K.3
Rinn, K.4
McNeel, D.G.5
-
17
-
-
0142062884
-
DNA vaccines: An active immunization strategy for prostate cancer
-
Wolchok JD, Gregor PD, Nordquist LT, Slovin SF, Scher HI. DNA vaccines: an active immunization strategy for prostate cancer. Semin Oncol 2003;30:659-66.
-
(2003)
Semin Oncol
, vol.30
, pp. 659-666
-
-
Wolchok, J.D.1
Gregor, P.D.2
Nordquist, L.T.3
Slovin, S.F.4
Scher, H.I.5
-
18
-
-
0036351282
-
Xenogeneic DNA immunization in melanoma models for minimal residual disease
-
Hawkins WG, Gold JS, Blachere NE, et al. Xenogeneic DNA immunization in melanoma models for minimal residual disease. J Surg Res 2002;102:137-43.
-
(2002)
J Surg Res
, vol.102
, pp. 137-143
-
-
Hawkins, W.G.1
Gold, J.S.2
Blachere, N.E.3
-
19
-
-
0029912726
-
Immune response to a differentiation antigen induced by altered antigen: A study of tumor rejection and autoimmunity
-
Naftzger C, Takechi Y, Kohda H, Hara I, Vijayasaradhi S, Houghton AN. Immune response to a differentiation antigen induced by altered antigen: a study of tumor rejection and autoimmunity. Proc Natl Acad Sci U S A 1996;93:14809-14.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14809-14814
-
-
Naftzger, C.1
Takechi, Y.2
Kohda, H.3
Hara, I.4
Vijayasaradhi, S.5
Houghton, A.N.6
-
20
-
-
0030299805
-
Autoantibody to p185erbB2/neu oncoprotein by vaccination with xenogenic DNA
-
Concetti A, Amici A, Petrelli C, Tibaldi A, Provinciali M, Venanzi FM. Autoantibody to p185erbB2/neu oncoprotein by vaccination with xenogenic DNA. Cancer Immunol Immunother 1996;43:307-15.
-
(1996)
Cancer Immunol Immunother
, vol.43
, pp. 307-315
-
-
Concetti, A.1
Amici, A.2
Petrelli, C.3
Tibaldi, A.4
Provinciali, M.5
Venanzi, F.M.6
-
21
-
-
0033432773
-
Coupling and uncoupling of tumor immunity and autoimmunity
-
Bowne WB, Srinivasan R, Wolchok JD, et al. Coupling and uncoupling of tumor immunity and autoimmunity. J Exp Med 1999;190:1717-22.
-
(1999)
J Exp Med
, vol.190
, pp. 1717-1722
-
-
Bowne, W.B.1
Srinivasan, R.2
Wolchok, J.D.3
-
22
-
-
0032531161
-
Tumor immunity and autoimmunity induced by immunization with homologous DNA
-
Weber LW, Bowne WB, Wolchok JD, et al. Tumor immunity and autoimmunity induced by immunization with homologous DNA. J Clin Invest 1998;102:1258-64.
-
(1998)
J Clin Invest
, vol.102
, pp. 1258-1264
-
-
Weber, L.W.1
Bowne, W.B.2
Wolchok, J.D.3
-
23
-
-
0033866842
-
Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity
-
Hawkins WG, Gold JS, Dyall R, et al. Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity. Surgery 2000;128:273-80.
-
(2000)
Surgery
, vol.128
, pp. 273-280
-
-
Hawkins, W.G.1
Gold, J.S.2
Dyall, R.3
-
24
-
-
33745829801
-
Vaccination with human tyrosinase DNA induces antibody responses in dogs with advanced melanoma
-
Liao JC, Gregor P, Wolchok JD, et al. Vaccination with human tyrosinase DNA induces antibody responses in dogs with advanced melanoma. Cancer Immun 2006;6:8.
-
(2006)
Cancer Immun
, vol.6
, pp. 8
-
-
Liao, J.C.1
Gregor, P.2
Wolchok, J.D.3
-
25
-
-
33747147093
-
Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center
-
Bergman PJ, Camps-Palau MA, McKnight JA, et al. Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center. Vaccine 2006;24:4582-5.
-
(2006)
Vaccine
, vol.24
, pp. 4582-4585
-
-
Bergman, P.J.1
Camps-Palau, M.A.2
McKnight, J.A.3
-
26
-
-
0034254472
-
In vivo generation of human dendritic cell subsets by Flt3 ligand
-
Maraskovsky E, Daro E, Roux E, et al. In vivo generation of human dendritic cell subsets by Flt3 ligand. Blood 2000;96:878-84.
-
(2000)
Blood
, vol.96
, pp. 878-884
-
-
Maraskovsky, E.1
Daro, E.2
Roux, E.3
-
27
-
-
0029661945
-
Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand - treated mice: Multiple dendritic cell subpopulations identified
-
Maraskovsky E, Brasel K, Teepe M, et al. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand - treated mice: multiple dendritic cell subpopulations identified. J Exp Med 1996;184:1953-62.
-
(1996)
J Exp Med
, vol.184
, pp. 1953-1962
-
-
Maraskovsky, E.1
Brasel, K.2
Teepe, M.3
-
28
-
-
0028318788
-
Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs
-
Hannum C, Culpepper J, Campbell D, et al. Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs. Nature 1994;368:643-8.
-
(1994)
Nature
, vol.368
, pp. 643-648
-
-
Hannum, C.1
Culpepper, J.2
Campbell, D.3
-
29
-
-
0042662868
-
Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo
-
Karsunky H, Merad M, Cozzio A, Weissman IL, Manz MG. Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J Exp Med 2003;198:305-13.
-
(2003)
J Exp Med
, vol.198
, pp. 305-313
-
-
Karsunky, H.1
Merad, M.2
Cozzio, A.3
Weissman, I.L.4
Manz, M.G.5
-
30
-
-
0035110962
-
Enhancement of DNA vaccine potency by linkage of antigen gene to a gene encoding the extracellular domain of Fms-like tyrosine kinase 3-ligand
-
Hung CF, Hsu KF, Cheng WF, et al. Enhancement of DNA vaccine potency by linkage of antigen gene to a gene encoding the extracellular domain of Fms-like tyrosine kinase 3-ligand. Cancer Res 2001;61:1080-8.
-
(2001)
Cancer Res
, vol.61
, pp. 1080-1088
-
-
Hung, C.F.1
Hsu, K.F.2
Cheng, W.F.3
-
31
-
-
0034662072
-
p185(neu) protein is required for tumor and anchorage-independent growth, not for cell proliferation of transgenic mammary carcinoma
-
Nanni P, Pupa SM, Nicoletti G, et al. p185(neu) protein is required for tumor and anchorage-independent growth, not for cell proliferation of transgenic mammary carcinoma. Int J Cancer 2000;87:186-94.
-
(2000)
Int J Cancer
, vol.87
, pp. 186-194
-
-
Nanni, P.1
Pupa, S.M.2
Nicoletti, G.3
-
32
-
-
0026472124
-
-
Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD, Muller WJ. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci U S A 1992;89:10578- 82.
-
Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD, Muller WJ. Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci U S A 1992;89:10578- 82.
-
-
-
-
33
-
-
0023713558
-
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
-
Muller WJ, Sinn E, Pattengale PK, Wallace R, Leder P. Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 1988;54:105-15.
-
(1988)
Cell
, vol.54
, pp. 105-115
-
-
Muller, W.J.1
Sinn, E.2
Pattengale, P.K.3
Wallace, R.4
Leder, P.5
-
34
-
-
0029997433
-
-
Guy CT, Cardiff RD, Muller WJ. Activated neu induces rapid tumor progression. J Biol Chem 1996;271:7673-8.
-
Guy CT, Cardiff RD, Muller WJ. Activated neu induces rapid tumor progression. J Biol Chem 1996;271:7673-8.
-
-
-
-
35
-
-
0037446542
-
Identification and characterization of the immunodominant rat HER-2/neu MHC class I epitope presented by spontaneous mammary tumors from HER-2/neu-transgenic mice
-
Ercolini AM, Machiels JP, Chen YC, et al. Identification and characterization of the immunodominant rat HER-2/neu MHC class I epitope presented by spontaneous mammary tumors from HER-2/neu-transgenic mice. J Immunol 2003;170:4273-80.
-
(2003)
J Immunol
, vol.170
, pp. 4273-4280
-
-
Ercolini, A.M.1
Machiels, J.P.2
Chen, Y.C.3
-
36
-
-
0031418442
-
Priming for T-cell - mediated rejection of established tumors by cutaneous DNA immunization
-
Ross HM, Weber LW, Wang S, et al. Priming for T-cell - mediated rejection of established tumors by cutaneous DNA immunization. Clin Cancer Res 1997;3:2191-6.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2191-2196
-
-
Ross, H.M.1
Weber, L.W.2
Wang, S.3
-
37
-
-
0032446987
-
Genetic immunization against neu/erbB2 transgenic breast cancer
-
Amici A, Venanzi FM, Concetti A. Genetic immunization against neu/erbB2 transgenic breast cancer. Cancer Immunol Immunother 1998;47:183-90.
-
(1998)
Cancer Immunol Immunother
, vol.47
, pp. 183-190
-
-
Amici, A.1
Venanzi, F.M.2
Concetti, A.3
-
38
-
-
33646396792
-
Optimization of a self antigen for presentation of multiple epitopes in cancer immunity
-
Guevara-Patino JA, Engelhorn ME, Turk MJ, et al. Optimization of a self antigen for presentation of multiple epitopes in cancer immunity. J Clin Invest 2006;116:1382-90.
-
(2006)
J Clin Invest
, vol.116
, pp. 1382-1390
-
-
Guevara-Patino, J.A.1
Engelhorn, M.E.2
Turk, M.J.3
-
39
-
-
0025726653
-
Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide
-
Schulz M, Aichele P, Schneider R, Hansen TH, Zinkernagel RM, Hengartner H. Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide. Eur J Immunol 1991;21:1181-5.
-
(1991)
Eur J Immunol
, vol.21
, pp. 1181-1185
-
-
Schulz, M.1
Aichele, P.2
Schneider, R.3
Hansen, T.H.4
Zinkernagel, R.M.5
Hengartner, H.6
-
40
-
-
0032504155
-
Structure-function analysis of FLT3 ligand-FLT3 receptor interactions using a rapid functional screen
-
Graddis TJ, Brasel K, Friend D, et al. Structure-function analysis of FLT3 ligand-FLT3 receptor interactions using a rapid functional screen. J Biol Chem 1998;273:17626-33.
-
(1998)
J Biol Chem
, vol.273
, pp. 17626-17633
-
-
Graddis, T.J.1
Brasel, K.2
Friend, D.3
-
41
-
-
0344234343
-
DNA immunisation: Altering the cellular localisation of expressed protein and the immunisation route allows manipulation of the immune response
-
Morel PA, Falkner D, Plowey J, Larregina AT, Falo LD. DNA immunisation: altering the cellular localisation of expressed protein and the immunisation route allows manipulation of the immune response. Vaccine 2004;22:447-56.
-
(2004)
Vaccine
, vol.22
, pp. 447-456
-
-
Morel, P.A.1
Falkner, D.2
Plowey, J.3
Larregina, A.T.4
Falo, L.D.5
-
42
-
-
0035116901
-
The collaboration of both humoral and cellular HER-2/neu-targeted immuneresponses is required for the complete eradication of HER-2/neu-expressing tumors
-
Reilly RT, Machiels JP, Emens LA, et al. The collaboration of both humoral and cellular HER-2/neu-targeted immuneresponses is required for the complete eradication of HER-2/neu-expressing tumors. Cancer Res 2001;61:880-3.
-
(2001)
Cancer Res
, vol.61
, pp. 880-883
-
-
Reilly, R.T.1
Machiels, J.P.2
Emens, L.A.3
-
44
-
-
0031468120
-
Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: Cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA immunization
-
Boyle JS, Koniaras C, Lew AM. Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA immunization. Int Immunol 1997;9:1897-906.
-
(1997)
Int Immunol
, vol.9
, pp. 1897-1906
-
-
Boyle, J.S.1
Koniaras, C.2
Lew, A.M.3
-
45
-
-
0043136619
-
+ T cell effector function and tumor-free survival in Her-2/neu-transgenic mice
-
+ T cell effector function and tumor-free survival in Her-2/neu-transgenic mice. J Immunol 2003;171:2161-9.
-
(2003)
J Immunol
, vol.171
, pp. 2161-2169
-
-
Wolpoe, M.E.1
Lutz, E.R.2
Ercolini, A.M.3
-
46
-
-
0037089544
-
Antihuman epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab enhances cytolytic activity of class I - restricted HER2-specific T lymphocytes against HER2-overexpressing tumor cells
-
zum Buschenfelde CM, Hermann C, Schmidt B, Peschel C, Bernhard H. Antihuman epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab enhances cytolytic activity of class I - restricted HER2-specific T lymphocytes against HER2-overexpressing tumor cells. Cancer Res 2002;62:2244-7.
-
(2002)
Cancer Res
, vol.62
, pp. 2244-2247
-
-
zum Buschenfelde, C.M.1
Hermann, C.2
Schmidt, B.3
Peschel, C.4
Bernhard, H.5
-
47
-
-
0032895775
-
Cellular requirements for the monoclonal antibody-mediated eradication of an established solid tumor
-
Dyall R, Vasovic LV, Clynes RA, Nikolic-Zugic J. Cellular requirements for the monoclonal antibody-mediated eradication of an established solid tumor. Eur J Immunol 1999;29:30-7.
-
(1999)
Eur J Immunol
, vol.29
, pp. 30-37
-
-
Dyall, R.1
Vasovic, L.V.2
Clynes, R.A.3
Nikolic-Zugic, J.4
-
48
-
-
0034234854
-
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2
-
Klapper LN, Waterman H, Sela M, Yarden Y. Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2. Cancer Res 2000;60:3384-8.
-
(2000)
Cancer Res
, vol.60
, pp. 3384-3388
-
-
Klapper, L.N.1
Waterman, H.2
Sela, M.3
Yarden, Y.4
-
49
-
-
1842426004
-
Trastuzumab (Herceptin) enhances class I-restricted antigen presentation recognized by HER-2/neu-specific T cytotoxic lymphocytes
-
Kono K, Sato E, Naganuma H, et al. Trastuzumab (Herceptin) enhances class I-restricted antigen presentation recognized by HER-2/neu-specific T cytotoxic lymphocytes. Clin Cancer Res 2004;10:2538-44.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2538-2544
-
-
Kono, K.1
Sato, E.2
Naganuma, H.3
|