Late-life depression: A review

Clinical Geriatrics

Volumn 15, Issue 10, 2007, Pages 35-44

  Das, Bidhan ^a   Greenspan, Michael ^b   Muralee, Sunanda ^b   Choe, Christine J ^c   Tampi, Rajesh R ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c RUSH MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AMFEBUTAMONE; ASPARAGINASE; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CIMETIDINE; CLONIDINE; CORTICOSTEROID; DULOXETINE; ESCITALOPRAM; ESTROGEN; FLUOXETINE; HYDRALAZINE; INTERLEUKIN 2; LEVODOPA; METHYLDOPA; MIRTAZAPINE; NORTRIPTYLINE; PAROXETINE; PROCARBAZINE; PROGESTERONE; RESERPINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TAMOXIFEN; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VENLAFAXINE; VINBLASTINE; VINCRISTINE;

ANTICHOLINERGIC EFFECT; APPETITE; BEREAVEMENT; BLOOD PRESSURE; BONE ATROPHY; BRAIN ATROPHY; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; CLINICAL FEATURE; COGNITIVE THERAPY; DAILY LIFE ACTIVITY; DEMENTIA; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIARRHEA; DISABILITY; DISEASE CLASSIFICATION; DISEASE EXACERBATION; ELECTROCONVULSIVE THERAPY; GASTROINTESTINAL SYMPTOM; GERONTOPSYCHIATRY; HEART INFARCTION; HUMAN; INFLAMMATION; INSOMNIA; INTERPERSONAL THERAPY; MAJOR DEPRESSION; NAUSEA; NEUROBIOLOGY; PARKINSON DISEASE; PROGNOSIS; PSEUDODEMENTIA; PSYCHIATRIC DIAGNOSIS; PSYCHOPHARMACOTHERAPY; PSYCHOTHERAPY; REVIEW; RISK FACTOR; SEDATION; SIDE EFFECT; SOCIAL ISOLATION; SOCIAL PSYCHOLOGY; SUICIDAL IDEATION; SUICIDE; WEIGHT GAIN; WEIGHT REDUCTION;

EID: 35549004091     PISSN: 10951598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (62)

1. Mulsant BH, Ganguli M. Epidemiology and diagnosis of depression in late life. J Clin Psychiatry 1999;60 Suppl 20:9-15.
2. Unutzer J, Katon W, Russo J, et al. Patterns of care for depressed older adults in a large-staff model HMO. Am J Geriatr Psychiatry 1999;7(3):235-43.
3. Fountoulakis KN, O'Hara R, Iacovides A, et al. Unipolar late-onset depression: A comprehensive review. Ann Gen Hosp Psychiatry 2003;2(1):11.
4. Harman JS, Schulberg HC, Mulsant BH, Reynolds CF. The effect of patient and visit characteristics on diagnosis of depression in primary care. J Fam Pract 2001;50(12):1068.
5. Taylor WD, Doraiswamy PM. A systematic review of antidepressant placebo-controlled trials for geriatric depression: Limitations of current data and directions for the future. Neuropsychopharmacology 2004;29(12):2285-2299.
6. Alexopoulos GS. Depression in the elderly. Lancet 2005; 365(9475):1961-1970.
7. Alexopoulos GS. New concepts for prevention and treatment of late-life depression. Am J Psychiatry 2001;158(6):835-838.
8. Dunner DL. Treatment considerations for depression in the elderly. CNS Spectr 2003;8(12 Suppl 3):14-19.
9. Thorpe L. The treatment of psychotic disorders in late life. Can J Psychiatry 1997;42 Suppl 1:19S-27S.
10. Myers JK, Weissman MM, Tischler GL, et al. Six-month prevalence of psychiatric disorders in three communities 1980 to 1982. Arch Gen Psychiatry 1984;41(10):959-967.
11. Gournellis R, Lykouras L, Fortos A, et al. Psychotic (delusional) major depression in late life: A clinical study. Int J Geriatr Psychiatry 2001;16(11):1085-1091. [Erratum in: Int J Geriatr Psychiatry 2002;17(3):296.]
12. Raskind MA. The clinical interface of depression and dementia. J Clin Psychiatry 1998;59 Suppl 10:9-12.
13. Reynolds CF 3rd, Smith GS, Dew MA, et al. Accelerating symptom-reduction in late-life depression: A double-blind, randomized, placebo-controlled trial of sleep deprivation. Am J Geriatr Psychiatry 2005;13(5):353-358.
14. Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatr Res 1982-1983;17(1):37-49.
15. Alexopoulos GS, Katz IR, Reynolds CF, et al. Pharmacotherapy of depression in older patients: A summary of the expert consensus guidelines. J Psychiatr Pract 2001;7(6):361-376.
16. Frasure-Smith N, Lesperance F, Talajic M. Depression following myocardial infarction. Impact on 6-month survival. JAMA 1993;270(15):1819-1825. [Erratum in: JAMA 1994;271(14):1082.]
17. Carney RM, Freedland KE. Depression, mortality, and medical morbidity in patients with coronary heart disease. Biol Psychiatry 2003;54(3):241-247.
18. Yaffe K, Blackwell T, Gore R, et al. Depressive symptoms and cognitive decline in nondemented elderly women: A prospective study. Arch Gen Psychiatry 1999;56(5):425-430.
19. Comijs HC, Jonker C, Beckman AT, Deeg DJ. The association between depressive symptoms and cognitive decline in community-dwelling elderly persons. Int J Geriatr Psychiatry 2001;16(4):361-367.
20. Wilson RS, Barnes LL, Mendes de Leon CF, et al. Depressive symptoms, cognitive decline, and risk of AD in older persons. Neurology 2002;59(3):364-370.
21. Lockwood KA, Alexopoulos GS, van Gorp WG. Executive dysfunction in geriatric depression. Am J Psychiatry 2002;159(7):1119-1126.
22. Butters MA, Whyte EM, Nebes RD, et al. The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry 2004;61(6):587-595.
23. Ko DT, Hebert PR, Coffey CS, et al. Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction. JAMA 2002;288(3):351-357.
24. Bruce ML. Psychosocial risk factors for depressive disorders in late life. Biol Psychiatry 2002;52(3):175-184.
25. Clyburn LD, Stones MJ, Hadjistavropoulos T, Tuokko H, et al. Predicting caregiver burden and depression in Alzheimer's disease. J Gerontol B Psychol Sci Soc Sci 2000;55(1):S2-S13.
26. Katon W, Lin E, von Korff M, et al. The predictors of persistence of depression in primary care. J Affect Disord 1994;31(2):81-90.
27. Lynch TR, Johnson CS, Mendelson T, et al. New onset and remission of suicidal ideation among a depressed adult sample. J Affect Disord 1999;56(1):49-54.
28. Duberstein PR. Openness to experience and completed suicide across the second half of life. Int Psychogeriatr 1995;7(2):183-198.
29. Goff VV. Depression: A decade of progress, more to do. NHPF Issue Brief 2002;(786):1-14.
30. Michelson D, Stratakis C, Hill L, et al. Bone mineral density in women with depression. N Engl J Med 1996;335(16):1176-1181.
31. Ferketich AK, Schwartzbaum JA, Frid DJ, Moeschberger ML. Depression as an antecedent to heart disease among women and men in the NHANES I study. National Health and Nutrition Examination Survey. Arch Intern Med 2000;160(9):1261-1268.
32. Greenberg PE, Kessler RC, Birnbaum HG, et al. The economic burden of depression in the United States: How did it change between 1990 and 2000? J Clin Psychiatry 2003;64(12): 1465-1475.
33. Johnson J, Weissman MM, Klerman GL. Service utilization and social morbidity associated with depressive symptoms in the community. JAMA 1992;267(11):1478-1483.
34. Croghan TW, Obenchain RL, Crown WE. What does treatment of depression really cost? Health Aff (Millwood) 1998;17(4): 198-208.
35. Turvey CL, Conwell Y, Jones MP, et al. Risk factors for late-life suicide: A prospective, community-based study. Am J Geriatr Psychiatry 2002;10(4):398-406.
36. American Psychiatric Association Practice Guidelines for the Treatment of Psychiatric Disorders 2004. Available at: www.psychiatryonline.com/content. aspx?aID=56008. Accessed August 11, 2007.
37. Sjosten N, Kivela SL. The effects of physical exercise on depressive symptoms among the aged: A systematic review. Int J Geriatr Psychiatry 2006;21(5):410-418.
38. Arean PA, Cook BL. Psychotherapy and combined psychotherapy/ pharmacotherapy for late life depression. Biol Psychiatry 2002;52(3):293-303.
39. Lenze EJ, Dew MA, Mazumdar S, et al. Combined pharmacotherapy and psychotherapy as maintenance treatment for late-life depression: Effects on social adjustment. Am J Psychiatry 2002;159(3):466-468.
40. Tollefson GD, Bosomworth JC, Heiligenstein JH, et al. A double-blind, placebo-controlled clinical trial of fluoxetine in geriatric patients with major depression. The Fluoxetine Collaborative Study Group. Int Psychogeriatr 1995;7(1):89-104.
41. Allard P, Gram L, Timdahl K, et al. Efficacy and tolerability of venlafaxine in geriatric outpatients with major depression: A double-blind, randomised 6-month comparative trial with citalopram. Int J Geriatr Psychiatry 2004;19(12):1123-1130.
42. Nelson JC, Wohlreich MM, Mallinckrodt CH, et al. Duloxetine for the treatment of major depressive disorder in older patients. Am J Geriatr Psychiatry 2005;13(3):227-235.
43. Schatzberg AF, Kremer C, Rodrigues HE, et al. Double-blind, randomized comparison of mirtazapine and paroxetine in elderly depressed patients. Am J Geriatr Psychiatry 2002;10(5):541-550.
44. Posternak MA, Zimmerman M. Switching versus augmentation: A prospective, naturalistic comparison in depressed, treatment-resistant patients. J Clin Psychiatry 2001;62(2):135-142.
45. Kamholz BA, Mellow AM. Management of treatment resistance in the depressed geriatric patient. Psychiatr Clin North Am 1996;19(2):269-286.
46. Whyte EM, Basinski J, Farhi P, et al. Geriatric depression treatment in nonresponders to selective serotonin reuptake inhibitors. J Clin Psychiatry 2004;65(12):1634-1641.
47. van der Wurff FB, Stek ML, Hoogendijk WJ, Beekman AT. The efficacy and safety of ECT in depressed older adults: A literature review. Int J Geriatr Psychiatry 2003;18(10):894-904.
48. Reynolds CF, Drew MA, Pollock BG, et al. Maintenance treatment of major depression in old age. N Engl J Med 2006;354(11):1130-1138.
49. Buffum MD, Buffum JC. Treating depression in the elderly: An update on antidepressants. Geriatr Nurs 2005;26(3):138-142.
50. Bartels SJ, Coakley EH, Zubritsky C, et al. Improving access to geriatric mental health services: A randomized trial comparing treatment engagement with integrated versus enhanced referral care for depression, anxiety, and at-risk alcohol use. Am J Psychiatry 2004;161(8):1455-1462.
51. Hunkeler EM, Meresman JF, Hargreaves WA, et al. Efficacy of nurse telehealth care and peer support in augmenting treatment of depression in primary care. Arch Fam Med 2000;9(8):700-708.
52. Sherbourne CD, Wells KB, Duan N, et al. Long-term effectiveness of disseminating quality improvement for depression in primary care. Arch Gen Psychiatry 2001;58(7):696-703.
53. Hunkeler EM, Katon W, Tang L, et al. Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care. BMJ 2006;332(7536):259-263. Epub 2006 Jan 20.
54. Mulsant BH, Alexopoulos GS, Reynolds, CF, et al; PROSPECT Study Group. Pharmacological treatment of depression in older primary care patients: The PROSPECT algorithm. Int J Geriatr Psychiatry 2001;16(6):585-592.
55. Bruce ML, Ten Have TR, Reynolds CF, et al. Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: A randomized controlled trial. JAMA 2004;291(9):1081-1091.
56. Alexopoulos GS, Katz IR, Bruce ML, et al; PROSPECT Group. Remission in depressed geriatric primary care patients: A report from the PROSPECT study. Am J Psychiatry 2005; 162(4):718-712.
57. Mitchell AJ, Subramaniam H. Prognosis of depression in old age compared to middle age: A systematic review of comparative studies. Am J Psychiatry 2005;162(9):1588-1601.
58. Salzman C, Wong E, Wright BC. Drug and ECT treatment of depression in the elderly, 1996-2001: A literature review. Biol Psychiatry 2002;52(3):265-284.
59. Reynolds CF 3rd, Frank E, Perel JM, et al. Nortriptyline and interpersonal psychotherapy as maintenance therapies for recurrent major depression: A randomized controlled trial in patients older than 59 years. JAMA 1999;281(1):39-45.
60. Blazer DG. Self-efficacy and depression in late life: A primary prevention proposal. Aging Ment Health 2002;6(4):315-324.
61. Rybarczyk B, DeMarco G, DeLaCruz M, Lapidos S. Comparing mind-body wellness interventions for older adults with chronic illness: Classroom versus home instruction. Behav Med 1999;24(4):181-190.
62. van't Veer-Tazelaar PJ, van Marwijk H, van Oppen P, et al. Prevention of anxiety and depression in the age group of 75 years and over: A randomised controlled trial testing the feasibility and effectiveness of a generic stepped care programme among elderly community residents at high risk of developing anxiety and depression versus usual care [ISRCTN26474556]. BMC Public Health 2006;6(1):186.