Unipolar late-onset depression: A comprehensive review

Annals of General Hospital Psychiatry

Volumn 2, Issue , 2003, Pages

  Fountoulakis, Konstantinos N ^a   O'Hara, Ruth ^b   Iacovides, Apostolos ^a   Camilleri, Christopher P ^b   Kaprinis, Stergios ^a   Kaprinis, George ^a   Yesavage, Jerome ^b  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Depression; Late life; Psychogeriatrics; Psychotherapy; SSRI's; TCA's

Indexed keywords

ANTIDEPRESSANT AGENT; DEXAMPHETAMINE; LITHIUM; METHYLPHENIDATE; MIANSERIN; MIRTAZAPINE; MOCLOBEMIDE; NEFAZODONE; PSYCHOSTIMULANT AGENT; SEROTONIN UPTAKE INHIBITOR; THYROID HORMONE; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

ANXIETY DISORDER; CARDIOVASCULAR DISEASE; CEREBROVASCULAR DISEASE; CLINICAL FEATURE; COGNITIVE DEFECT; CULTURAL FACTOR; DIARRHEA; DISEASE SEVERITY; DIZZINESS; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG TOLERABILITY; DRUG TOXICITY; FALLING; GASTROINTESTINAL SYMPTOM; GROUPS BY AGE; HUMAN; INSOMNIA; MAJOR DEPRESSION; MEDICAL LITERATURE; MEDICAL RESEARCH; MENTAL PERFORMANCE; NAUSEA; ONSET AGE; ORTHOSTATIC HYPOTENSION; PHYSICAL DISEASE; PREVALENCE; PROGNOSIS; PSYCHOLOGIC ASSESSMENT; PSYCHOTHERAPY; RESTLESSNESS; REVIEW; SEDATION; SEXUAL DYSFUNCTION; SIDE EFFECT; SOCIOECONOMICS; VALIDATION PROCESS; VOMITING;

EID: 3042609762     PISSN: 14752832     EISSN: None     Source Type: Journal    
DOI: 10.1186/1475-2832-2-11     Document Type: Review

References (161)

1. Shah A, De T: Documented Evidence of Depression in Medical and Nursing Case-Notes and its Implications in Acutely III Geriatric Inpatients. International Psychogeriatrics 1998, 10:163-172.
2. Parmelee PA, Kalz IR, Lawton MP: Depression and Mortality Among Institutionalized Aged. Journal of Gerontology and Psychological Sciences 1992, 47:P3-P10.
3. Murphy E: The Course and Outcome of Depression in Late Life. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz BD and Friedhoff A. Washington DC, American Psychiatric Press; 1994:81-98.
4. Vaillant GE, Orav J, Meyer SE, McCullough Vaillant L, Roston D: Late-Life Consequences of Affective Spectrum Disorder. International Psychogeriatrics 1996, 8:13-32.
5. Blazer D, Burchetti B, Service C, et al: The Association of Age in Depression Among the Elederly: An Epidemiologic Exploration. Journal of Gerontology 1991, 46:M210-M215.
6. Reynolds CF: Treatment of Depression in Special Populations. Journal of Clinical Psychiatry 1992, 53 (suppl 9):45-53.
7. Branconnierm RJ, Cole JO, Ghazvinian D, Spera KF, Oxenkrug GF, Bass JL: Clinical Pharmacology of Bupropion and Imipramine in Elderly Depressives. Journal of Clinical Psychiatry 1983, 44:130-133.
8. Rapp SR, Parisi SA, Walsh DA: Psychological Dysfunction and Physical Health Among Elderly Medical Inpatients. Journal of Consulting and Clinical Psychology 1988, 56:851-855.
9. Katz IR, Lesher E, Kleban M, Jethanandani V, Parmelee PA: Clinical Features of Depression in the Nursing Home. International Psychogeriatrics 1989, 1:5-15.
10. Foster JR, Cataldo JK, Boksay IJE: Incidence of Depression in a Medical Long-Term Facility: Findings From a Restricted Sample of New Admissions. International Journal of Geriatric Psychiatry 1991, 6:13-20.
11. Parmelee PA, Kleban MH, Lawton MP, Katz IR: Depression and Cognitive Change Among Institutionalized Aged. Psychology and Aging 1991, 6:504-511.
12. NIH: Consensus Development Panel on Depression in Late Life: Diagnosis and Treatment of Depression in Late Life. JAMA 1992, 268:1018-1024.
13. Katz IR, Parmelee PA: Depression in Elderly Patients Residential Care Settings. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz BD and Fiedhoff A. Washington DC, American Psychiatric Press; 1994:437-442.
14. Weyerer S, Hafner H, Mann A, Ames D, Graham N: Prevalence and Course of Depression Among Elderly Residential Home Admissions in Mannheim and Camden, London. International Psychogeriatrics 1995, 7:479-493.
15. Caine ED, Lyness JM, King DA: Reconsidering Depression in the Elderly. American Journal of Geriatric Psychiatry 1993, 1:4-20.
16. Hopkinson G: A Genetic Study of Affective Illness in Patients over 50. British Journal of Psychiatry 1964, 110:244-254.
17. Mendlewicz J: The Age Factor in Depressive Illness: Some Genetic Consideration. Journal of Gerontology 1976, 31:300-303.
18. Jacoby RJ, Levy R: Computed Tomography in the Elderly-3: Affective Disorder. British Journal of Psychiatry 1980, 136:270-275.
19. Burvill PW, Hall WD, Stampfer HG, Emmerson JP: A Comparison of Early Onset and Late Onset Depressive Illness in the Elderly. British Journal of Psychiatry 1989, 155:673-679.
20. Rabins RV, Pearlson GD, Aylward E, Kumar AJ, Dowell K: Cortical Magnetic Resonance Imaging Changes in Elderly Impatients with Major Depression. American Journal of Psychiatry 1991, 148:617-620.
21. Monfort JC: The Difficult Elderly Patient: Curable Hostile Depression or Personality Disorder? International Psychogeriatrics 1995, 7:95-111.
22. Lader M: Differential Diagnosis of Anxiety in the Elderly. Journal of Clinical Psychiatry 1982, 43:4-7.
23. Nelson JC, Conwell Y, Kim K, Mazure C: Age at Onset in Late Life Delusional Depression. American Journal of Psychiatry 1989, 146:785-786.
24. Musetti L, Perugi G, Soriani A, Rossi VM, Cassano GB: Depression Before and After Age 65: A Re-examination. British Journal of Psychiatry 1989, 155:330-336.
25. Brown RP, Sweeney J, Loutsch E, Kocsis J, Frances A: Involutional Melancholia Revisited. American Journal of Psychiatry 1984, 141:24-28.
26. Lyness JM, Conwell Y, Nelson JC: Suicide Attempts in Elderly Psychiatric Inpatients. Journal of the American Geriatrics Society 1992, 40:320-324.
27. Fruedhoff A: Consensus Panel Report. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz BD and Friedhoff A. Washington DC, American Psychiatric Press; 1994:493-511.
28. Wiener P, Alexopoulos GS, Kakuma T, Meyers BS, Rosenthal E, Chester J: The limits of history-taking in geriatric depression. American Journal of Geriatric Psychiatry 1997, 5:116-125.
29. APA: Diagnostic and Statistical Manual of Mental Disorders. 4thth edition. Washington DC, American Psychiatric Press; 1994:465.
30. Glasser M, Gravdal JA: Assessment and treatment of geriatric depression in primary care settings. Archives of Family Medicine 1997, 6:433-438.
31. Modai I, Bleich A, Gygielman G: Masked Depression: An Ambiguous Entity. Psychotherapy and Psychosomatics 1982, 37:235-240.
32. Kishi Y, Robinson RG, Kosier JT: Suicidal Plans in Patients with Stroke: Comparison Between Acute-Onset and Delayed-Onset Suicidal Plans. International Psychogeriatrics 1996, 8:623-634.
33. Flint AJ: Epidemiology and Comorbidity of Anxiety Disorders in the Elderly. American Journal of Psychiatry 1994, 151:640-649.
34. Gurian BS, Miner JH: Clinical Presentation of Anxiety in the Elderly. Anxiety in the Elderly: Treatment and Research Edited by: Salzman C and Lebowitz BD. New York, Springer Publishing Company; 1991:31-44.
35. Shamoian CA: What is Anxiety in the Elderly? Anxiety in the Elderly: Treatment and Research Edited by: Salzman C and Lebowitz BD. New York, Springer Publishing Company; 1991:3-12.
36. Alexopoulos GS: Anxiety and Depression in the Elderly. Anxiety in the Elderly: Treatment and Research Edited by: Salzman C and Lebowitz B. New York, Springer Publishing Company; 1991:63-74.
37. Collins E, Katona C, Orrell M: Diagnosis and Management of Depression in Old Age. Focus on Depression 1994, 2:1-5.
38. Rutz W: Prevention of Suiside. Lancet 1992, 340:1233-1234.
39. Conwell Y, Brent D: Suicide and Aging I: Patterns of Psychiatric Diagnosis. International Psychogeriatrics 1995, 7:149-164.
40. Heikkinen ME, Lonnqvist JK: Recent Life Events in Elderly Suicide: A Nationwide Study in Finland. International Psychogeriatrics 1995, 7:287-300.
41. Association American Psychiatric: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). Washington D.C., American Psychiatric Press; 1994:p. 465.
42. Murphy E: The Prognosis of Depression in Old Age. British Journal of Psychiatry 1983, 142:111-119.
43. Baldwin RC: Delusional and Non-Delusional Depression in late Life: Evidence for Distinct Subtypes. British Journal of Psychiatry 1988, 152:39-44.
44. Kiloh LG: Pseudodementia. Acta Psychiatrica Scandinavica 1961, 37:336-351.
45. Plotkin DA, Mints J, Jarvik LF: Subjective Memory Complaints in Geriatric Depression. American Journal of Psychiatry 1985, 142:1103-1105.
46. Goodman CR, Zarit SH: Ecological Measures of Cognitive Functioning: A Validation Study. International Psychogeriatrics 1995, 7:39-50.
47. McAllister TW: Cognitive Functioning in the Affective Disorders. Comprehensive Psychiatry 1981, 22:572-586.
48. Shraberg D: The Myth of Pseudodementia: Depression and the Aging Brain. American Journal of Psychiatry 1978, 135:601-603.
49. Poon LW: Toward an Understanding of Cognitive Functioning in Geriatric Depression. International Psychogeriatrics 1992, 4:241-266.
50. Yaffe K, Blackwell T, Gore R, Sands L, Reus V, Browner WS: Depressive symptoms and cognitive decline in nondemented elderly women: a prospective study. Arch Gen Psychiatry 1999, 56:425-430.
51. Comijs HC, Jonker C, Beekman AT, Deeg DJ: The association between depressive symptoms and cognitive decline in community-dwelling elderly persons. Int J Geriatr Psychiatry 2001, 16:361-367.
52. Wilson RS, Barnes LL, Mendes de Leon CF, Aggarwal NT, Schneider JS, Bach J, Pilat J, Beckett LA, Arnold SE, Evans DA, Bennett DA: Depressive symptoms, cognitive decline, and risk of AD in older persons. Neurology 2002, 59:364-370.
53. Nebes RD, Butters MA, Houck PR, Zmuda MD, Aizenstein H, Pollock BG, Mulsant BH, Reynolds CF: Dual-task performance in depressed geriatric patients. Psychiatry Res 2001, 102:139-151.
54. Nebes RD, Butters MA, Mulsant BH, Pollock BG, Zmuda MD, Houck PR, Reynolds CF: Decreased working memory and processing speed mediate cognitive impairment in geriatric depression. Psychol Med 2000, 30:679-691.
55. Alexopoulos GS, Meyers B, Young RC, Kalayam B, Kakuma T, Gabrielle M, Sirey JA, Hull J: Executive dysfunction and long-term outcomes of geriatric depression. Arch Gen Psychiatry 2000, 57:285-290.
56. Kalayam B, Alexopoulos GS: Prefrontal dysfunction and treatment response in geriatric depression. Arch Gen Psychiatry 1999, 56:713-718.
57. Mehta KM, Yaffe K, Langa KM, Sands L, Whooley MA, Covinsky KE: Additive Effects of Cognitive Function and Depressive Symptoms on Mortality in Elderly Community-Living Adults. Journal of Gerontology 2003, 58A:461-467.
58. Simpson SW, Baldwin RC, Burns A, Jackson A: Regional cerebral volume measurements in late-life depression: relationship to clinical correlates, neuropsychological impairment and response to treatment. Int J Geriatr Psychiatry 2001, 16:469-476.
59. Bajulaiye R, Alexopoulos G: Pseydodementia in Geriatric Depression. Functional Psychiatric Disorders of the Elderly Edited by: Chiu E and Ames D. Cambridge University Press; 1994:126-141.
60. Cohen-Mansfield J, Billig N: Agitated Behaviors in the Elderly. A Conceptual Review. Journal of the American Geriatrics Society 1986, 34:711-721.
61. Cohen-Mansfield J, Marxs MS, Rosenthal AS: A Description of Agitation in a Nursing Home. Journal of Gerontology 1989, 44:M77-M84.
62. Cohen-Mansfield J, Marxs MS, Werner P: Agitation in Elderly Persons: An Integrative Report of Findings in a Nursing Home. International Psychogeriatrics 1992, 4:221-240.
63. Friedman R, Gryfe CI, Tal DT,, Freedman M: The Noisy Elderly Patient: Prevalence, Assessment and Response to the Antidepressant Doxepin. Journal of Geriatric Psychiatry and Neurology 1992, 5:187-191.
64. Singer K: Depressive Disorders form a Transcultural Perspective. Social Science and Medicine 1975, 9:289-306.
65. Kleinman A: Depression, Somatization and the New Cross-Cultural Psychiatry. Social Science and Medicine 1977, 11:3-10.
66. Comstock G, Helsing K: Symptoms of Depression in Two Communities. Psychological Medicine 1976, 6:551-563.
67. Hasegawa K: The Epidemiology of Depression in Later Life. Journal of Affective Disorders 1985, suppl 1:3-6.
68. Cheng T: Symptomatology of Minor Psychiatric Morbidiy: A Cross-Cultural Comparison. Psychological Medicine 1989, 19:697-708.
69. Markides K, Jackson J, Liang J: Race, Ethnicity and Aging: Conceptual and Methodological Issues. Handbook of Aging and the Social Sciences Edited by: Binstock R and George L. San Diego, Academic Press; 1990.
70. Marsella A: The Measurement of Depressive Experience and Disorder Across Cultures. The Measurement of Depression Edited by: Marsella A, Hirschfeld R and Katz M. New York, Guilford Press.
71. Lin T: Culture and Psychiatry: A Chinese Perspective. Australia and New Zeland Journal of Psychiatry 1982, 16:235-245.
72. Krause N, Liang J: Cross-Cultural Variations in Depressive Symptoms in Later Life. International Psychogeriatrics 1992, 4:185-202.
73. Moscicki EK: Epidemiology of Suicide-North American Perspectives. International Psychogeriatrics 1995, 7:137-148.
74. Silveira ER, Ebrahim S: Social Determinants of Psychiatric Morbidity and Well-Being in Immigrant Elders and Whites in East London. International Journal of Geriatric Psychiatry 1998, 11:801-812.
75. Koenig HG, Cohen HJ, Blazer DG, al. et: Religious Coping and Depression Among Elderly Hospitalized Medically III Men. American Journal of Psychiatry 1992, 149:1693-1700.
76. Koenig HG, Cohen HJ, Blazer DG,, al. et: Religious Coping and Cognitive Symptoms of Depression Among Elderly Medical Patients. Psychosomatics 1995, 36:369-375.
77. Jakoby RJ, Lewy R, Bird JM: Computed Tomography in the Elderly: Affective Disorders. British Journal of Psychiatry 1980, 136:270-275.
78. Greenwald BS, Kramer-Ginsberg E, Krishnan RR, Ashtari M, Aupperle PM, Patel M: MRI Signal Hyperintensities in Geriatric Depression. American Journal of Psychiatry 1996, 153:1212-1215.
79. Jakoby RJ, Lewy R, Bird JM: Computed Tomography and the Outcome of Affective Disorders: A Follow-up Study of Elderly Patients. British Journal of Psychiatry 1981, 139:288-292.
80. Uradhyaya AK, Abou-Saleh MT, Wilson K, Grime SJ, Critchley M: A Study of Depression in Old Age Using SPECT. British Journal of Psychiatry 1990, 157:76-81.
81. Sackheim HA, Prohonik I, Moeller JR, al. et: Regional Cerebral Blood Flow in Mood Disorders II. Comparison of Major Depression and Alzheimer's Disease. Journal of Nuclear Medicine 1993, 34:1090-1101.
82. Steffens DC, Krishnan RR: Structural Neuroimaging and Mood Disorders: Recent Findings, Implications for Classification and Future Directions. Biological Psychiatry 1998, 43:705-712.
83. Drevets WC: Geriatric Depression: Brain Imaging Correlates and Pharmacologic Considerations. Journal of Clinical Psychiatry 1994, 55:71-81.
84. Salloway S, Malloy P, Kohn R, Gillard E, Duffy J, Rogg J, Tung G, Richardson E, Thomas C, Westlake R: MRI and Neuropsychological Differences in Early- and Late-life-Onset Geriatric Depression. Neurology 1996, 46:1567-1574.
85. Ballard C, Bannister C, Solis M, Oyebode F, Wilcock G: The Prevalence, Associations and Symptoms of Depression Amongst Dementia Sufferers. Journal of Affective Disorders 1996, 36:135-144.
86. Meyers BS, Alpert S, Gebriele M, Kakuma T, Kalayam B, Alexopoulos GS: State Specificity of DST Abnormalities in Geriatric Depression. Biological Psychiatry 1993, 34:108-114.
87. Nemeroff C, Knight DL, Krishnan RR, Slotkin TA, Bissette G, Melville ML, Blazer DG: Marked Reduction in the Number of Platelet-Titriated Imipramine Binding Sites in Geriatric Depression. Archives of General Psychiatry 1988, 45:919-923.
88. Doyle MC, George AJ, Ravindran AV, Philppott R: Platelet alpha 2-adrenoreceptor binding in elderly depressed patients. American Journal of Psychiatry 1985, 142:1489-1490.
89. Teicher MH, Lawrence JM, Barber NI, Finklestein SP, Lieberman HR, Baldessarini RJ: Increased Activity and Phase Delay in Circadian Motility Rhythms in Geriatric Depression. Archives of General Psychiatry 1988, 45:913-917.
90. Reynolds CF, Kupfer DJ, Houck PR, Hoch CC, Stack JA, Berman SR, Zimmer B: Reliable Discrimination of Elderly Depressed and Demented Patients by EEG Sleep Data. Archives of General Psychiatry 1988, 45:258-264.
91. Leake A, Charlton BG, Lowry PJ, Jackson S, Fairbairn A, Ferrier IN: Plasma N-POMC, ACTH and Cortisol Concentrations in a Psychogeriatric Population. British Journal of Psychiatry 1990, 156:676-679.
92. Lerer B, Gillon D, al. et: Interelationship of Age, Depression and Central Serotonergic Function: Evidence from Fenfluramine Challenge Studies. International Psychogeriatrics 1996, 8:83-102.
93. Husain MM, Knight DL, al. et: Platelet [3H]-Imipramine Binding and Leukoencephalopathy in Geriatric Depression. Biological Psychiatry 1991, 29:665-670.
94. Holmes C: Apolipoprotein E and Functional Illness in the Elderly. International Psychogeriatrics 1998, 10:3-6.
95. Mauricio M, O'Hara R, Yesavage JA, Friedman LF, Kraemer HC, Van Deer Water M, Murphy GM: A Longitudinal Study of Apolipoprotein-e Genotype and Depressive Symptoms in Community-Dwelling Older Adults. American Journal of Geriatric Psychiatry 2000, 8:1-4.
96. Burns A, Jacoby R, Levy R: Psychiatric Phenomena in Alzheimer's Disease-III: Disorders of Mood. British Journal of Psychiatry 1990, 157:81-86.
97. Merriam A, Aronson N, Gaston P, al. et: The Psychiatric Symptoms of Alzheimer's Disease. Journal of the American Geriatrics Society 1988, 36:7-12.
98. Zubenko GS, Moossy J, Kop U: Neurochemical Correlates of Major Depression in Primary Dementia. Archives of Neurology 1990, 47:209-214.
99. Lopez OL, Boller F, Becker JT, Miller M, Reynolds CF: Alzheimers Disease and Depression: Neuropsychological Impairment and Progression of the Illness. American Journal of Psychiatry 1990, 147:855-860.
100. Huber SJ, Paulson GW: The Concept of Subcortical Dementia. American Journal of Psychiatry 1985, 142:1312-1316.
101. Jenicke MA: Assessment and Treatment of Affective Illness in the Elderly. Journal of Geriatric Psychiatry and Neurology 1988, 1:89-107.
102. Caine ED, Lyness JM, King DA: Reconsidering Depression in the Elderly. American Journal of Geriatric Psychiatry 1993, 1:4-20.
103. Prince MJ, Harwood RH, Thomas A, Mann AH: A Prospective Population-Based Cohort Study of the Effects of Disablement and Social Milieu on the Onset and Maintenance of Late-Life Depression. The Gospel Oak Project VII. Psychological Medicine 1998, 2:337-350.
104. Kok RM, Heeren TJ, Hooijer C, al. et: The Prevalence of Depression in Elderly Medical Inpatients. Journal of Affective Disorders 1995, 33:77-82.
105. Kitchell MA, Barnes RF, Veith RC, al. et: Screening for Depression in Hospitalized Geriatric Medical Patients. Journal of the American Geriatrics Society 1982, 30:174-177.
106. Williamson GM, Schulz R: Pain, Activity Restriction and Symptoms of Depression Among Community-Residing Elderly Adults. Journal of Gerontology 1992, 47:367-372.
107. Koenig HG: Differences in Psychosocial and Health Correlates of Major and Minor Depression in Medically Ill Older Adults. Journal of the American Geriatrics Society 1997, 45:1487-1495.
108. Lipsey JR, Robinson RG, Pearlson GD, Rao K, Price TR: Nortriptyline Treatment of Post Stroke Depression: A Double-Blind Study. Lancet 1984, 1:297-300.
109. Koenig HG, George LK: Depression and Physical Disability Outcomes in Depressed Medically Ill Hospitalized Older Adults. American Journal of Geriatric Psychiatry 1998, 6:230-247.
110. Steffens DC, Hays JC, Krishnan KR: Disability in Geriatric Depression. American Journal of Geriatric Psychiatry 1999, 7:34-40.
111. Dhondt ADF, Hooijer C: Iatrogenic Origins of Depression in the Elderly. International Journal of Geriatric Psychiatry 1995, 10:1-8.
112. Alexopoulos G: Biological Markers in Geriatric Depression. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz B and Fiedhoff A. Washington DC, American Psychiatric Press; 1994:99-116.
113. Caine ED, Lyness JM, King DA, Connors L: Clinical and Etiological Heterogeneity of Mood Disorders in the Elderly. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz B and Fiedhoff A. Washington DC, American Psychiatric Press; 1994:23-53.
114. Millard PH: Depression in Old Age. British Medical Journal 1983, 287:375-376.
115. Alexopoulos GS, Chester JG: Outcomes of Geriatric Depression. Clinical Geriatric Medicine 1992, 8:363-376.
116. Burvill P: The Outcome of Depressive Illness in Old Age. Functional Psychiatric Disorders of the Elderly Edited by: Chiu E and Ames D. Cambridge, University Press; 1994:111-125.
117. Georgotas A, McCue R, Cooper TB, Nagachandran N, Chang I: How Effective and Safe is Continuation Therapy in Elderly Depressed Patients. Archives of General Psychiatry 1988, 45:929-933.
118. Henrichsen GA: Recovery and Relapse from Major Depressive Disorder in the Elderly. American Journal of Psychiatry 1992, 149:1575-1579.
119. Scott J: Chronic Depression. British Journal of Psychiatry 1988, 153:287-297.
120. Persson G: Five-Year Mortality in a 70-year Old Urban Population in Relation to Psychiatric Diagnosis, Personality, Sexuality and Early Parental Death. Acta Psychiatrica Scandinavica 1981, 64:244-253.
121. Tennant C: Parental Loss in Childhood: Its Effects in Adult Life. Archives of General Psychiatry 1988, 45:1045-1050.
122. Kendler KS, Kessler RC, Neale MC, Health AC, Eaves LJ: The Prediction of Major Depression in Women: Toward an Integrated Etiological Model. American Journal of Psychiatry 1993, 150:1139-1148.
123. Kivela SL, Luukinen H, Koski K, Viramo P, Pahkala K: Early Loss of Mother or Father Predicts Depression in Old Age. International Journal of Geriatric Psychiatry 1998, 13:527-530.
124. Cole MG: The Prognosis of Depression in the Elderly. Canadian Medical Association Journal 1990, 143:633-640.
125. Gershon SC, Plotkin DA, Jarvik LF: Antidepressant Drug Studies, 1964 to 1986: Empiracal Evidence for Aging Patients. Journal of Clinical Psychopharmacology 1988, 8:311-322.
126. Schneider LS: Meta-Analysis from a Clinician's Perspective. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz B and Fiedhoff A. Washington DC, American Psychiatric Press; 1994:361-374.
127. Klawansky S: Meta-Analysis on the Treatment of Depression in Late Life. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz B and Fiedhoff A. Washington DCq, American Psychiatric Press; 1994:331-352.
128. Stoudemire A, Hill CD, Marquardt M, Dalton S, Lewison BJ: Recovery and Relapse in Geriatric Depression after Treatment with Antidepressants and ECT in a Medical-Psychiatric Population. General Hospital Psychiatry 1998, 20:170-174.
129. Montgomery SA, James D, Montgomery DB: Pharmacological Specificity is not the Same as Clinical Selectivity. Clinical Pharmacology in Psychiatry Edited by: Dahl, Gram, Paul and Potter. Berlin, Springer; 1987:179-183.
130. Von Moltke L, Greenblatt DJ, Shader RI: Clinical Pharmacokinetics of Antidepressants in the Elderly. Clinical Pharmacokinetics 1993, 24:141-160.
131. Furlanut M, Benetello P: The Pharmacokinetics of Tricyclic Antidepressant Drugs in the Elderly. Pharmacological Research 1990, 22:15-25.
132. Katona CLE: The Epidemiology of Depression in Old Age. Treatment and Care in Old Age Psychiatry Edited by: Levy R, Howard R and Burns A. Petersfield, Wrightson Biomedical Publishing; 1993:157-167.
133. Barlett HL, Puhl SM, Hodgson JL, Buskirk ER: Fat-Free Mass in Relation to Stature: Ratios of Fat-Free Mass to Height in Children, Adults and Elderly Subjects. American Journal of Clinical Nutrition 1991, 53:1112-1116.
134. Frank E: Long Term Prevention of Recurrences in Elderly Patients. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz BD and Fiedhoff A. Washington DC, American Psychiatric Press; 1994:317-329.
135. Group Old Age Depression Interest: How Long Should the Elderly Take Antidepressants? A Double Blind Placebo-Controlled Study of Continuation/Prophylaxis Therapy with Dothiepin. British Journal of Psychiatry 1993, 162:175-182.
136. Reynolds CF, Frank E, Perel JM, Mazumdar S, Kupfer D: Maintenance Therapies for Late-Life Recurrent Major Depression: Research and Review Circa. International Psychogeriatrics 1995, 7(suppl):27-39.
137. Woodhouse K: The Pharmacology of Major Tranquillisers in the Elderly. Delusions and Hallucinations in Old Age Edited by: Katona C and Levy R. London, Gaskell; 1992.
138. Glassman AH, Roose SP: Risks of Antidepressants in the Elderly: Tricyclic Antidepressants and Arrhythmia-Revising Risks. Gerontology 1994, 40:15-20.
139. Orrell MW, Baldwin B, Callin E, Katona C: A UK National Survey of the Management of Depression by Geriatricians and Old Age Psychiatrists. International Journal of Geriatric Psychiatry 1995, 10:457-167.
140. Preskorn SH: Recent Pharmacologic Advances in Antidepressant Therapy for the Elderly. American Journal of Medicine 1993, 94:2S-12S.
141. Jenicke MA: Treatment of Affective Illness in the Elderly with Drugs and Electroconvulsive Therapy. Journal of Geriatric Psychiatry 1989, 22:77-112.
142. Salzman C: Pharmacological Treatment of Depression in the Elderly. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds CF, Lebowitz BD and Fiedhoff A. Washington DC, American Psychiatric Press; 1994:181-244.
143. Dunn RL, Donoghue JM, Ozminkowski RJ, Stephenson D, Hylan TR: Longitudinal Patterns of Antidepressant Prescribing in Primary Care in the UK: Comparison with Treatment Guidelines. Journal of Psychopharmacology 1999, 13:136-143.
144. Preskorn SH, Beber JH, Faul JC, Hirschfeld RM: Serious Adverse Effects of Combining Fluoxetine and Tricyclic Antidepressants. American Journal of Psychiatry 1990, 147:532-540.
145. Leonard BE: Comparative Pharmacology of New Antidepressants. Journal of Clinical Psychiatry 1993, 54:3-15.
146. Noveske FG, Hahn KR, Flynn RJ: Possible Toxicity of Combined Fluoxetine and Lithium. American Journal of Psychiatry 1989, 146:1515-1521.
147. Satel SL, Nelson JC: Stimulants in the Treatment of Depression: A Critical Review. Journal of Clinical Psychiatry 1989, 50:241-249.
148. Picket P, Masand P, Murray GB: Psychostimulant Treatment of Geriatric Depressive Disorders Secondary to Medicla Illness. Journal of Geriatric Psychiatry and Neurology 1990, 3:146-151.
149. Drimmer EJ, Gitlin MJ, Guortsman HE: Desipramine and Methylphenidate Combination Treatment for Depression. American Journal of Psychiatry 1983, 140:241-250.
150. Goodwin FK, Prange AJ, Post RM, Muscettola G, Lipton MA: Potentiation of Antidepressant Effects by L-Triiodothyronine in Tricyclic Nonresponders. American Journal of Psychiatry 1982, 139:34-38.
151. Cowe D, Collins JP, Rosse RB: Thyroid Hormone Supplementation of Fluoxetine Treatment. Journal of Clinical Psychopharmacology 1990, 10:150-151.
152. Finch E, Katona C: Lithium Augmentation in the Treatment of Refractory Depression in Old Age. International Journal of Geriatic Psychiatry 1989, 4:41-46.
153. Sackheim HA: Use of Electroconculsive Therapy in Late-Life Depression. Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference Edited by: Schneider LS, Reynolds C, Lebowitz B and Fiedhoff A. Washington DC, American Psychiatric Press; 1994:259-277.
154. Benbow MS: Electroconculsive Therapy in Later Life. Functional Psychiatric Disorders of the Elderly Edited by: Chiu E and Ames D. Cambridge, Cambridge University Press; 1994:440-460.
155. Lazarus LW, Groves L, Newton N, Gutman D, Ripeckyl A: Brief Psychotherapy With the Elderly: A Review and Preliminary Study and Outcome. Psychotherapy with the Elderly Edited by: Lazarus L. Washington D.C., American Psychiatric Press; 1984:15-35.
156. Alexopoulos GS, Vrontou C, Kakuma T, Meyers BS, Young RC, Klausner E, Clarkin J: Disability in Geriatric Depression. American Journal of Psychiatry 1996, 153:877-885.
157. Sadavoy J: Integrated Psychotherapy of the Elderly. Functional Psychiatric Disorders of the Elderly Edited by: Chiu E and Ames D. Cambridge University Press; 1994:499-517.
158. Rabins P, Folstein M: The Classification of Functional Psychiatric Disorders in the Elderly in DSM-III-R and DSM-IV. Functional Psychiatric Disorders of the Elderly Edited by: Chiu E and Ames D. Cambridge University press; 1994:17-28.
159. Van Praag HM, Kahn RS, Asnis GM, al. et: Denosologization of Biological Psychiatry or the Specificity of 5-HT Disturbances in Psychiatric Disorders. J Affect Dis 1987, 13:1-8.
160. Kay SR: Diagnostic Edition of the PANSS (SID-PANSS). Positive and Negative Syndromes in Schizophrenia-Assessment and Research Edited by: Kay SR. New York, Brunner-Mazel Publishers; 1991:105-127.
161. Unutzer J, Katon W, Callahan C, Williams JW, Hunkeler E,, Harpole L, Hoffing M, Della Penna RD, Noel PH, Lin EHB, Arean P, Hegel M, L Tang, Belin TR, Oishi S, Langston C: Collaborative care management of late-life depression in the primary care setting. JAMA 2002, 288:2836-2845.