Remission in depressed geriatric primary care patients: A report from the PROSPECT study

American Journal of Psychiatry

Volumn 162, Issue 4, 2005, Pages 718-724

  Alexopoulos, George S ^a   Katz, Ira R ^b   Bruce, Martha L ^b   Heo, Moonseong ^b   Ten Have, Thomas ^b   Raue, Patrick ^b   Bogner, Hillary R ^b   Schulberg, Herbert C ^b   Mulsant, Benoit H ^b   Reynolds III, Charles F ^b  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALGORITHM; ANXIETY; ARTICLE; CAREGIVER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DISEASE SEVERITY; EMOTION; FEMALE; GERIATRIC CARE; HAMILTON SCALE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH CARE; PATIENT ATTITUDE; PREDICTION; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REMISSION; RISK ASSESSMENT; RISK FACTOR; SUICIDAL BEHAVIOR;

AGED; ALGORITHMS; DEPRESSIVE DISORDER, MAJOR; FEMALE; HEALTH SERVICES FOR THE AGED; HUMANS; MALE; PATIENT CARE MANAGEMENT; PATIENT CARE PLANNING; PATIENT COMPLIANCE; PHYSICIAN'S PRACTICE PATTERNS; PRACTICE GUIDELINES; PRIMARY HEALTH CARE; PROBABILITY; PSYCHIATRIC STATUS RATING SCALES; REFERRAL AND CONSULTATION; RESEARCH DESIGN; RISK FACTORS; TREATMENT OUTCOME; UNITED STATES; UNITED STATES AGENCY FOR HEALTHCARE RESEARCH AND QUALITY;

EID: 20144387158     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.162.4.718     Document Type: Article

References (39)

1. Paykel ES, Ramana R, Cooper Z, Hayhurst H, Kerr J, Barocka A: Residual symptoms after partial remission: an important outcome in depression. Psychol Med 1995; 25:1171-1180
2. Judd LL, Akiskal HS, Maser JD, Zeller PJ, Endicott J, Coryell W, Paulus MP, Kunovac JL, Leon AC, Mueller TI, Rice JA, Keller MB: Major depressive disorder: a prospective study of residual sub-threshold depressive symptoms as predictor of rapid relapse. J Affect Disord 1996; 50:97-108
3. Thase ME, Entsuah AR, Rudolph RL: Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry 2001; 178:234-241
4. Whyte EM, Dew MA, Gildngers A, Lenze EJ, Bharucha A, Mulsant BH, Reynolds CF III: Time course of response to antidepressants in late-life major depression: therapeutic implications. Drugs Aging 2004; 21:531-554
5. Fortney J, Rost K, Zhang M: A joint choice model of the decision to seek depression treatment and choice of provider sector. Med Care 1998; 36:307-320
6. Brody DS, Khaliq AA, Thompson TL: Patients' perspectives on the management of emotional distress in primary care. J Gen Intern Med 1997; 12:403-406
7. Leaf PJ, Bruce ML, Tischler GL, Holzer CE: The relationship between demographic factors and attitudes toward mental health services. J Community Psychol 1987; 15:275-284
8. Luber MP, Alexopoulos GS, Hollenberg J, Charlson M, Callahan M: Recognition, treatment, comorbidity, and resource utilization of depressed patients in a general medical practice (abstract). J Gen Intern Med 1996; 11(May suppl):134
9. Harman JS, Mulsant BH, Kelleher KJ, Schulberg HC, Kupfer DJ, Reynolds CF III: Narrowing the gap in the treatment of depression. Int J Geriatr Psychiatry 2001; 31:239-253
10. Unützer J, Katon W, Callahan CM, Williams JW Jr, Hunkeler E, Harpole L, Hoffing M, Della Penna RD, Noel PH, Lin EH, Tang L, Oishi S: Depression treatment in a sample of 1,801 depressed older adults in primary care. J Am Geriatr Soc 2003; 51:505-514
11. Cramer JA, Rosenheck R: Compliance with medication regimens for mental and physical disorders. Psychiatr Serv 1998; 49:196-201
12. Gilbody S, Whitty P, Grimshaw J, Thomas R: Educational and organizational interventions to improve the management of depression in primary care: a systematic review. JAMA 2003; 289: 3145-3151
13. Rollman BL, Hanusa BH, Lowe HJ, Gilbert T, Kapoor WN, Schulberg HC: A randomized trial using computerized decision support to improve treatment of major depression in primary care. J Gen Intern Med 2002; 17:493-503
14. Wells KB, Sherbourne C, Schoenbaum M, Duan N, Meredith L, Unutzer J, Miranda J, Carney MF, Rubenstein LV: Impact of disseminating quality improvement programs for depression in managed primary care: a randomized controlled trial. JAMA 2000; 283:212-220; correction, 283:3204
15. Unutzer J, Katon W, Callahan CM, Williams JW Jr, Hunkeler E, Harpole L, Hoffing M, Della Penna RD, Noel PH, Lin EH, Arean PA, Hegel MT, Tang L, Belin TR, Oishi S, Langston C (IMPACT [Improving Mood-Promoting Access to Collaborative Treatment] Investigators): Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA 2002; 288:2836-2845
16. Katon W, Von Korff M, Lin E, Simon G, Walker E, Unutzer J, Bush T, Russo J, Ludman E: Stepped collaborative care for primary care patients with persistent symptoms of depression. Arch Gen Psychiatry 1999; 56:1109-1115
17. Bruce ML, Ten Have TR, Reynolds CF III, Katz IR, Schulberg HC, Mulsant BH, Brown GK, McAvay GJ, Pearson JL, Alexopoulos GS: Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: a randomized controlled trial. JAMA 2004; 291:1081-1091
18. Depression Guideline Panel: Clinical Practice Guideline Number 2: Treatment of Major Depression, 5: Depression in Primary Care: AHCPR Publication 93-0551. Rockville, Md, US Department of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, 1993
19. Hamilton M: A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62
20. Radloff LS: The CES-D Scale: a self-report depression scale for research in the general population. J Applied Psychol Measurement 1977; 1:385-401
21. Raue PJ, Alexopoulos GS, Bruce ML, Klimstra S, Mulsant BH, Gallo JJ (PROSPECT Study Group): The systematic assessment of depressed elderly primary care patients. Int J Geriatr Psychiatry 2001; 16:560-569
22. Mulsant BH, Alexopoulos GS, Reynolds CF, Katz IR, Abrams RC, Oslin D, Schulberg HC (PROSPECT Study Group): Pharmacological treatment of depression in older primary care patients: the PROSPECT algorithm. Int J Geriatr Psychiatry 2001; 16:585-592
23. Brown GK, Bruce ML, Pearson JL: High-risk management guidelines for elderly suicidal patients in primary care settings. Int J Geriatr Psychiatry 2001; 16:593-601
24. First M, Spitzer R, Williams J, Gibbon M: Structured Clinical Interview for DSM-IV-Non-Patient Edition (SCID-NP, Version 1.0). Washington, DC, American Psychiatric Press, 1995
25. Beck AT, Kovacs M, Weissman A: Assessment of suicidal intention: the Scale for Suicide Ideation. J Consult Clin Psychol 1979; 47:343-352
26. Snaith RP, Baugh SJ, Clayden AD, Husain A, Sipple MA: The Clinical Anxiety Scale: an instrument derived from the Hamilton Anxiety Scale. Br J Psychiatry 1982; 141:518-523
27. Beck AT, Steer RA, Beck JS, Newman CF: Hopelessness, depression, suicidal ideation, and clinical diagnosis of depression. Suicide Life Threat Behav 1993; 23:139-145
28. Folstein MF, Folstein SE, McHugh PR: "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12:189-198
29. Ware J Jr, Kosinski M, Keller SD: A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care 1996; 34:220-233
30. Alexopoulos GS, Meyers BS, Young RC, Kakuma T, Feder M, Einhorn A, Rosendahl E: Recovery in geriatric depression. Arch Gen Psychiatry 1996; 53:305-312
31. Ten Have TR, Uttal DH: Subject-specific and population-averaged continuous ratio logit models for multiple discrete time survival profiles. Appl Stat 1994; 43:371-384
32. Ten Have TR, Localio AR: Empirical Bayes estimation of random effects parameters in mixed effects logistic regression models. Biometrics 1999; 55:1022-1029
33. Littell RC, Milliken GA, Stroup WW, Wolfinger RD: SAS System for Mixed Models. Cary, NC, SAS Institute, 1996, pp 445-447
34. Kleinbaum DG, Klein M: Logistic Regression: A Self-Learning Text, 2nd ed. New York, Springer, 2002
35. Heiligenstein JH, Ware JE, Beusterien KM, Roback PJ, Beusterian KM, Roback PJ, Andrejasich C, Tollefson GD: Acute effects of fluoxetine versus placebo on functional health and well being in late-life depression. Int Psychogeriatr 1997; 7(suppl): 125-137
36. Weishaar ME, Beck AT: Hopelessness and suicide. Int Rev Psychiatry 1992; 4:177-184
37. Dyer JAT, Kreitman N: Hopelessness; depression, and suicidal intent in parasuicide. Br J Psychiatry 1984; 144:127-133
38. Uncarper H, Gallagher-Thompson D, Osgood NJ, Bongar B: Hopelessness and suicidal ideation in older adults. Gerontologist 1998; 38:62-70
39. Gorman JM: Comorbid depression and anxiety spectrum disorders. Depress Anxiety 1996; 4:160-168