X radiation up-regulates the occurrence and the multiplicity of invasive carcinomas in the intestinal tract of Apcmin/+ mice

Radiation Research

Volumn 168, Issue 4, 2007, Pages 433-439

  Nakayama, Toshiyuki ^a   Yamazumi, Kazuyuki ^a   Uemura, Takashi ^a   Yoshizaki, Ayumi ^a   Yakata, Yuichi ^a   Matsuu Matsuyama, Mutsumi ^a   Shichijo, Kazuko ^a   Sekine, Ichiro ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN;

ADENOMATOUS POLYP; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST TUMOR; CONTROLLED STUDY; FEMALE; GENE MUTATION; INTESTINE CARCINOMA; INVASIVE CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION CARCINOGENESIS; STATISTICAL SIGNIFICANCE; UPREGULATION; WILD TYPE; X IRRADIATION; X RAY; ANIMAL; C57BL MOUSE; CANCER INVASION; INTESTINE TUMOR; RADIATION INJURY; TUMOR SUPPRESSOR GENE;

ANIMALIA; MUS;

ANIMALS; FEMALE; GENES, APC; INTESTINAL NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; NEOPLASMS, RADIATION-INDUCED; X-RAYS;

EID: 35548964591     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR0869.1     Document Type: Article

References (50)

1. A. R. Moser, H. C. Pitot and W. F. Dove, A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322-324 (1990).
2. A. R. Moser, C. Luongo, K. A. Gould, M. K. McNeley, A. R. Shoemaker and W. F. Dove, ApcMin: a mouse model for intestinal and mammary tumorigenesis. Eur. J. Cancer 31, 1061-1064 (1995).
3. A. R. Shoemaker, K. A. Gould, C. Luongo, A. R. Moser and W. F. Dove, Studies of neoplasia in the Min mouse. Biochim. Biophys. Acta 1332, F25-F48 (1997).
4. L. K. Su, K. W. Kinzler, B. Vogelstein, A. C. Preisinger, A. R. Moser, C. Luongo, K. A. Gould and W. F. Dove, Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 256, 668-670 (1992).
5. K. A. Silverman, R. Koratkar, L. D. Siracusa and A. M. Buchberg, Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia. Genome Res. 12, 88-97 (2002).
6. W. F. Dietrich, E. S. Lander, J. S. Smith, A. R. Moser, K. A. Gould, C. Luongo, N. Borenstein and W. Dove, Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 75, 631-639 (1993).
7. M. MacPhee, K. P. Chepenik, R. A. Liddell, K. K. Nelson, L. D. Siracusa and A. M. Buchberg, The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia. Cell 81, 957-966 (1995).
8. R. T. Cormier, K. H. Hong, R. B. Halberg, T. L. Hawkins, P. Richardson, R. Mulherkar, W. F. Dove and E. S. Lander, Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis. Nat. Genet. 17, 88-91 (1997).
9. Min/+ Mom1S mice. Proc. Natl. Acad. Sci. USA 102, 2868-2873 (2005).
10. S. M. Powell, N. Zilz, Y. Beazer-Barclay, T. M. Bryan, S. R. Hamilton, S. N. Thibodeau, B. Vogelstein and K. W. Kinzle, APC mutations occur early during colorectal tumorigenesis. Nature 359, 235-237 (1992).
11. J. Groden, A. Thliveris, W. Samowitz, M. Carlson, L. Gelbert, H. Albertsen, G. Joslyn, J. Stevens, L. Spirio and R. White, Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66, 589-600 (1991).
12. I. Nishisho, Y. Nakamura, Y. Miyoshi, Y. Miki, H. Ando, A. Horii, K. Koyama, J. Utsunomiya, S. Baba and P. Hedge, Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253, 665-669 (1991).
13. A. D. Spigelman and R. K. S. Phillips, The upper gastrointestinal tract. In Familial Adenomatous Polyposis and Other Polyposis Syndromes (R. K. S. Phillips, A. D. Spigelman and J. P. S. Thompson, Eds.), pp. 128-142. Edward Arnold, London, 1994.
14. M. C. A. Brett, M. J. Hershmann and G. Glazer, Other manifestations of familial adenomatous polyposis. In Familial Adenomatous Polyposis and Other Polyposis Syndromes (R. K. S. Phillips, A. D. Spigelman and J. P. S. Thompson, Eds.), pp. 128-142. Edward Arnold, London, 1994.
15. K. C. R. Farmer, P. R. Hawle and R. K. S. Phillips, Desmoid Disease. In Familial Adenomatous Polyposis and Other Polyposis Syndromes (R. K. S. Phillips, A. D. Spigelman and J. P. S. Thompson, Eds.), pp. 128-142. Edward Arnold, London, 1994.
16. T. Anthony, M. A. Rodriguez-Bigas, T. K. Weber and N. J. Petrelli, Desmoid tumors. J. Am. Coll. Surg. 182, 369-377 (1996).
17. K. J. Smith, D. B. Levy, P. Maupin, T. D. Pollard, B. Vogelstein and K. W. Kinzler, Wild-type but not mutant APC associates with the microtubule cytoskeleton. Cancer Res. 54, 3672-3675 (1994).
18. S. Munemitsu, B. Souza, O. Muller, I. Albert, B. Rubinfeld and P. Polakis, The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res. 54, 3676-3681 (1994).
19. A. Matsumine, A. Ogai, T. Senda, N. Okumura, K. Satoh, G. H. Baeg, T. Kawahara, S. Kobayashi, M. Okada and T. Akiyama, Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein. Science 272, 1020-1023 (1996).
20. B. Rubinfeld, I. Albert, E. Porfiri, C. Fiol, S. Munemitsu and P. Polakis, Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 272, 1023-1026 (1996).
21. B. Rubinfeld, B. Souza, I. Albert, O. Muller, S. H. Chamberlain, F. R. Masiarz, S. Munemitsu and P. Polakis, Association of the APC gene product with beta-catenin. Science 262, 1731-1734 (1993).
22. L. K. Su, B. Vogelstein and K. W. Kinzler, Association of the APC tumor suppressor protein with catenins. Science 262, 1734-1737 (1993).
23. M. Peifer, Regulating cell proliferation: as easy as APC. Science 272, 974-975 (1996).
24. P. J. Morin, A. B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein and K. W. Kinzler, Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 275, 1787-1790 (1997).
25. -/- colon carcinoma. Science 275, 1784-1787 (1997).
26. X. Huang and B. Guo, Adenomatous polyposis coli determines sensitivity to histone deacetylase inhibitor-induced apoptosis in colon cancer cells. Cancer Res. 66, 9245-9251 (2006).
27. P. J. Morin, B. Vogelstein and K. W. Kinzler, Apoptosis and APC in colorectal tumorigenesis. Proc. Natl. Acad. Sci. USA 93, 7950-7954 (1996).
28. 1 to S phase. EMBO J. 14, 5618-5625 (1995).
29. D. E. Thompson, K. Mabuchi, E. Ron, M. Soda, M. Tokunaga, S. Ochikubo, S. Sugimoto, T. Ikeda, M. Terasaki and D. L. Preston, Cancer incidence in atomic bomb survivors. Part II: Solid tumors, 1958-1987. Radiat. Res. 137 (Suppl.), S17-S67 (1994).
30. A. C. Upton, Ed., Radiation Carcinogenesis. Elsevier Science, Amsterdam, 1986.
31. J. D. Boice, Radiation carcinogenesis in the gut. In Radiation and Gut (C. S. Potten and J. H. Henry, Eds.), pp. 291-305. Elsevier Science, Amsterdam, 1995.
32. C. W. van der Houven van Oordt, R. Smits, S. L. Williamson, A. Luz, P. M. Khan, R. Fodde, A. J. van der Eb and M. L. Breuer, Intestinal and extra-intestinal tumor multiplicities in the Apc1638N mouse model after exposure to X-rays. Carcinogenesis 18, 2197-2203 (1997).
33. C. W. van der Houven van Oordt, R. Smits, T. G. Schouten, J. J. Houwing-Duistermaat, S. L. Williamson, A. Luz, P. M. Khan, A. J. van der Eb, M. L. Breuer and R. Fodde, The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc1638N mouse model. Genes Chromosomes Cancer 24, 191-198 (1999).
34. Min/+ mice. Radiat. Res. 163, 552-556 (2005).
35. Min/+ mice to radiation-induced intestinal neoplasia. Int. J. Radiat. Biol. 82, 141-151 (2006).
36. M. Okamoto and H. Yonekawa, Intestinal tumorigenesis in Min mice is enhanced by X-irradiation in an age-dependent manner. J. Radiat. Res. (Tokyo) 46, 83-91 (2005).
37. H. Oshima, M. Oshima, M. Kobayashi, M. Tsutsumi and M. M. Taketo, Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice. Cancer Res. 57, 1644-1649 (1997).
38. A. R. Shoemaker, C. Luongo, A. R. Moser, L. J. Marton and W. F. Dove, Somatic mutational mechanisms involved in intestinal tumor formation in Min mice. Cancer Res. 57, 1999-2006 (1997).
39. A. Andreassen, R. Vikse, A. Mikalsen, T. Adamovic, I. L. Steffensen, H. Hjertholm, G. Levan and J. Alexander, 2-Amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) induces genetic changes in murine intestinal tumours and cells with ApcMin mutation. Mutat. Res. 604, 60-70 (2006).
40. C. Flynn, D. C. Montrose, D. L. Swank, M. Nakanishi, J. N. Ilsley and D. W. Rosenberg, Deoxycholic acid promotes the growth of colonic aberrant crypt foci. Mol. Carcinog. 46, 60-70 (2007).
41. M. Nakashima, S. Meirmanov, R. Matsufuji, M. Hayashida, E. Fukuda, S. Naito, M. Matsuu, K. Shichijo, H. Kondo and I. Sekine, Altered expression of beta-catenin during radiation-induced colonic carcinogenesis. Pathol. Res. Pract. 198, 717-724 (2002).
42. O. Tamai, E. Nozato, H. Miyazato, T. Isa, S. Hiroyasu, M. Shiraishi, T. Kusano, Y. Muto and M. Higashi, Radiation-associated rectal cancer: report of four cases. Dig. Surg. 16, 238-243 (1999).
43. United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR), Sources and Effects of Ionizing Radiation. United Nations, New York, 1998.
44. C. E. Land, M. Tokunaga, K. Koyama, M. Soda, D. L. Preston, I. Nishimori and S. Tokuoka, Incidence of female breast cancer among atomic bomb survivors, Hiroshima and Nagasaki, 1950-1990. Radiat. Res. 160, 707-717 (2003).
45. E. D. Williams, A. Abrosimov, T. Bogdanova, E. P. Demidchik, M. Ito, V. LiVolsi, E. Lushnikov, J. Rosai, Y. Sidorov and G. A. Thomas, Thyroid carcinoma after Chernobyl latent period, morphology and aggressiveness. Br. J. Cancer 90, 2219-2224 (2004).
46. M. Nakanishi, K. Tanaka, T. Takahashi, T. Kyo, H. Dohy, M. Fujiwara and N. Kamada, Microsatellite instability in acute myelocytic leukaemia developed from A-bomb survivors. Int. J. Radiat. Biol. 77, 687-694 (2001).
47. Y. E. Nikiforov, A. Koshoffer, M. Nikiforova, J. Stringer and J. A. Fagin, Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas. Oncogene 18, 6330-6334 (1999).
48. S. Sasaki and N. Fukuda, Temporal variation of excess mortality rate from solid tumors in mice irradiated at various ages with gamma rays. J. Radiat. Res. (Tokyo) 46, 1-19 (2005).
49. B. Vogelstein, E. R. Fearon, S. R. Hamilton, S. E. Kern, A. C. Preisinger, M. Leppert, Y. Nakamura, R. White, A. M. Smits and J. L. Bos, Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 319, 525-532 (1988).
50. Min/+mice is enhanced by X irradiation with a characteristic age dependence. Radiat. Res. 165, 165-173 (2006).