메뉴 건너뛰기




Volumn 604, Issue 1-2, 2006, Pages 60-70

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces genetic changes in murine intestinal tumours and cells with ApcMin mutation

Author keywords

A J; AKR J; Allelic ratio; Apc; Chromosome; Intestine; Microsatellites; Min; PhIP; Tumour

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; APC PROTEIN;

EID: 33646475539     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.01.004     Document Type: Article
Times cited : (11)

References (47)
  • 4
    • 0033393815 scopus 로고    scopus 로고
    • A new approach to risk estimation of food-borne carcinogens - heterocyclic amines - based on molecular information
    • Nagao M. A new approach to risk estimation of food-borne carcinogens - heterocyclic amines - based on molecular information. Mutat. Res. 431 (1999) 3-12
    • (1999) Mutat. Res. , vol.431 , pp. 3-12
    • Nagao, M.1
  • 5
    • 0025768966 scopus 로고
    • A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
    • Ito N., Hasegawa R., Sano M., Tamano S., Esumi H., Takayama S., and Sugimura T. A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis 12 (1991) 1503-1506
    • (1991) Carcinogenesis , vol.12 , pp. 1503-1506
    • Ito, N.1    Hasegawa, R.2    Sano, M.3    Tamano, S.4    Esumi, H.5    Takayama, S.6    Sugimura, T.7
  • 7
    • 0024854930 scopus 로고
    • Induction of lymphoma in CDF1 mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
    • Esumi H., Ohgaki H., Kohzen E., Takayama S., and Sugimura T. Induction of lymphoma in CDF1 mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Jpn. J. Cancer Res. 80 (1989) 1176-1178
    • (1989) Jpn. J. Cancer Res. , vol.80 , pp. 1176-1178
    • Esumi, H.1    Ohgaki, H.2    Kohzen, E.3    Takayama, S.4    Sugimura, T.5
  • 8
    • 0029682493 scopus 로고    scopus 로고
    • Inhibition of 2-Amino-1-methyl-6-phenylimidazo[4,5]pyridine-induced lymphoma formation by oltipraz
    • Rao C.V., Rivenson A., Zang E., Steele V., Kelloff G., and Reddy B.S. Inhibition of 2-Amino-1-methyl-6-phenylimidazo[4,5]pyridine-induced lymphoma formation by oltipraz. Cancer Res. 56 (1996) 3395-3398
    • (1996) Cancer Res. , vol.56 , pp. 3395-3398
    • Rao, C.V.1    Rivenson, A.2    Zang, E.3    Steele, V.4    Kelloff, G.5    Reddy, B.S.6
  • 9
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler K.W., and Vogelstein B. Lessons from hereditary colorectal cancer. Cell 87 (1996) 159-170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 10
    • 0036270763 scopus 로고    scopus 로고
    • The subcellular destinations of APC proteins
    • Bienz M. The subcellular destinations of APC proteins. Nat. Rev. Mol. Cell Biol. 3 (2002) 328-338
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 328-338
    • Bienz, M.1
  • 11
    • 0037341566 scopus 로고    scopus 로고
    • Asef are involved in the migration of colorectal tumour cells
    • Kawasaki Y., Sato R., Akiyama T., and Mutated A.P.C. Asef are involved in the migration of colorectal tumour cells. Nat. Cell Biol. 5 (2003) 211-215
    • (2003) Nat. Cell Biol. , vol.5 , pp. 211-215
    • Kawasaki, Y.1    Sato, R.2    Akiyama, T.3    Mutated, A.P.C.4
  • 13
    • 0029047954 scopus 로고
    • Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
    • Oshima M., Oshima H., Kitagawa K., Kobayashi M., Itakura C., and Taketo M. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc. Natl. Acad. Sci. U.S.A 92 (1995) 4482-4486
    • (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 4482-4486
    • Oshima, M.1    Oshima, H.2    Kitagawa, K.3    Kobayashi, M.4    Itakura, C.5    Taketo, M.6
  • 18
    • 0037173075 scopus 로고    scopus 로고
    • Intestinal adenomas can develop with a stable karyotype and stable microsatellites
    • Haigis K.M., Caya J.G., Reichelderfer M., and Dove W.F. Intestinal adenomas can develop with a stable karyotype and stable microsatellites. Proc. Natl. Acad. Sci. U.S.A 99 (2002) 8927-8931
    • (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 8927-8931
    • Haigis, K.M.1    Caya, J.G.2    Reichelderfer, M.3    Dove, W.F.4
  • 19
    • 0031417627 scopus 로고    scopus 로고
    • 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine increases the numbers of tumors, cystic crypts and aberrant crypt foci in multiple intestinal neoplasia mice
    • Steffensen I.-L., Paulsen J.E., Eide T.J., and Alexander J. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine increases the numbers of tumors, cystic crypts and aberrant crypt foci in multiple intestinal neoplasia mice. Carcinogenesis 18 (1997) 1049-1054
    • (1997) Carcinogenesis , vol.18 , pp. 1049-1054
    • Steffensen, I.-L.1    Paulsen, J.E.2    Eide, T.J.3    Alexander, J.4
  • 20
    • 0032814733 scopus 로고    scopus 로고
    • Neonatal exposure to the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine via breast milk or directly induces intestinal tumors in multiple intestinal neoplasia mice
    • Paulsen J.E., Steffensen I.-L., Andreassen A., Vikse R., and Alexander J. Neonatal exposure to the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine via breast milk or directly induces intestinal tumors in multiple intestinal neoplasia mice. Carcinogenesis 20 (1999) 1277-1282
    • (1999) Carcinogenesis , vol.20 , pp. 1277-1282
    • Paulsen, J.E.1    Steffensen, I.-L.2    Andreassen, A.3    Vikse, R.4    Alexander, J.5
  • 22
    • 0347683364 scopus 로고    scopus 로고
    • Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice
    • Møllersen L., Vikse R., Andreassen A., Steffensen I.-L., Mikalsen A., Paulsen J.E., and Alexander J. Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice. Mutat. Res. 557 (2004) 29-40
    • (2004) Mutat. Res. , vol.557 , pp. 29-40
    • Møllersen, L.1    Vikse, R.2    Andreassen, A.3    Steffensen, I.-L.4    Mikalsen, A.5    Paulsen, J.E.6    Alexander, J.7
  • 24
    • 0025773878 scopus 로고
    • Metabolic activation and cytogenetic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in Chinese hamster ovary cells expressing murine cytochrome P450 IA2
    • Buonarati M.H., Tucker J.D., Minkler J.L., Wu R.W., Thompson L.H., and Felton J.S. Metabolic activation and cytogenetic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) in Chinese hamster ovary cells expressing murine cytochrome P450 IA2. Mutagenesis 6 (1991) 253-259
    • (1991) Mutagenesis , vol.6 , pp. 253-259
    • Buonarati, M.H.1    Tucker, J.D.2    Minkler, J.L.3    Wu, R.W.4    Thompson, L.H.5    Felton, J.S.6
  • 25
    • 0028601263 scopus 로고
    • Derivation of conditionally immortalized cell lines containing the Min mutation from the normal colonic mucosa and other tissues of an "Immortomouse"/Min hybrid
    • Whitehead R.H., and Joseph J.L. Derivation of conditionally immortalized cell lines containing the Min mutation from the normal colonic mucosa and other tissues of an "Immortomouse"/Min hybrid. Epithelial Cell Biol. 3 (1994) 119-125
    • (1994) Epithelial Cell Biol. , vol.3 , pp. 119-125
    • Whitehead, R.H.1    Joseph, J.L.2
  • 26
    • 0018144586 scopus 로고
    • The courtenay clonogenic assay
    • Courtenay D. The courtenay clonogenic assay. Br. J. Cancer 38 (1978) 77-81
    • (1978) Br. J. Cancer , vol.38 , pp. 77-81
    • Courtenay, D.1
  • 27
    • 0034122380 scopus 로고    scopus 로고
    • Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane
    • Takahashi M., Nakatsugi S., Sugimura T., and Wakabayashi K. Frequent mutations of the beta-catenin gene in mouse colon tumors induced by azoxymethane. Carcinogenesis 21 (2000) 1117-1120
    • (2000) Carcinogenesis , vol.21 , pp. 1117-1120
    • Takahashi, M.1    Nakatsugi, S.2    Sugimura, T.3    Wakabayashi, K.4
  • 28
    • 0024450988 scopus 로고
    • Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen
    • Loeber G., Tevethia M.J., Schwedes J.F., and Tegtmeyer P. Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen. J. Virol. 63 (1989) 4426-4430
    • (1989) J. Virol. , vol.63 , pp. 4426-4430
    • Loeber, G.1    Tevethia, M.J.2    Schwedes, J.F.3    Tegtmeyer, P.4
  • 29
    • 0023480636 scopus 로고
    • A new fixation procedure for quality G-bands in routine cytogenetic work
    • Islam M.Q., and Levan G. A new fixation procedure for quality G-bands in routine cytogenetic work. Hereditas 107 (1987) 127-130
    • (1987) Hereditas , vol.107 , pp. 127-130
    • Islam, M.Q.1    Levan, G.2
  • 30
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser A.R., Pitot H.C., and Dove W.F. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247 (1990) 322-324
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 31
    • 0035893757 scopus 로고    scopus 로고
    • Intestinal tumorigenesis in multiple intestinal neoplasia mice induced by the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine: perinatal susceptibility, regional variation, and correlation with DNA adducts
    • Steffensen I.-L., Schut H.A.J., Paulsen J.E., Andreassen A., and Alexander J. Intestinal tumorigenesis in multiple intestinal neoplasia mice induced by the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine: perinatal susceptibility, regional variation, and correlation with DNA adducts. Cancer Res. 61 (2001) 8689-8696
    • (2001) Cancer Res. , vol.61 , pp. 8689-8696
    • Steffensen, I.-L.1    Schut, H.A.J.2    Paulsen, J.E.3    Andreassen, A.4    Alexander, J.5
  • 33
    • 0343238142 scopus 로고    scopus 로고
    • Genomewide assessment of genetic alterations in DMBA-induced rat sarcomas: cytogenetic, CGH, and allelotype analyses reveal recurrent DNA copy number changes in rat chromosomes 1, 2, 4, and 7
    • Walentinsson A., Sjoling A., Helou K., Klinga-Levan K., and Levan G. Genomewide assessment of genetic alterations in DMBA-induced rat sarcomas: cytogenetic, CGH, and allelotype analyses reveal recurrent DNA copy number changes in rat chromosomes 1, 2, 4, and 7. Genes Chromosomes Cancer 28 (2000) 184-195
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 184-195
    • Walentinsson, A.1    Sjoling, A.2    Helou, K.3    Klinga-Levan, K.4    Levan, G.5
  • 34
    • 33646477490 scopus 로고    scopus 로고
    • I.-L. Steffensen, J. Alexander. Impact of genetic background on spontaneous or 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumourigenesis in Min/+ mice. Cancer Lett. 2005 Dec 9 [Epub ahead of print].
  • 36
    • 0035496104 scopus 로고    scopus 로고
    • APC, signal transduction and genetic instability in colorectal cancer
    • Fodde R., Smits R., and Clevers H. APC, signal transduction and genetic instability in colorectal cancer. Nat. Rev. Cancer 1 (2001) 55-67
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 55-67
    • Fodde, R.1    Smits, R.2    Clevers, H.3
  • 38
    • 0029982877 scopus 로고    scopus 로고
    • The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration
    • Näthke I.S., Adams C.L., Polakis P., Sellin J.H., and Nelson W.J. The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. J. Cell Biol. 134 (1996) 165-179
    • (1996) J. Cell Biol. , vol.134 , pp. 165-179
    • Näthke, I.S.1    Adams, C.L.2    Polakis, P.3    Sellin, J.H.4    Nelson, W.J.5
  • 39
    • 0034614936 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells
    • Mimori-Kiyosue Y., Shiina N., and Tsukita S. Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells. J. Cell Biol. 148 (2000) 505-518
    • (2000) J. Cell Biol. , vol.148 , pp. 505-518
    • Mimori-Kiyosue, Y.1    Shiina, N.2    Tsukita, S.3
  • 41
    • 0033865758 scopus 로고    scopus 로고
    • Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesis
    • Papanikolaou A., Wang Q.S., Papanikolaou D., Whiteley H.E., and Rosenberg D.W. Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesis. Carcinogenesis 21 (2000) 1567-1572
    • (2000) Carcinogenesis , vol.21 , pp. 1567-1572
    • Papanikolaou, A.1    Wang, Q.S.2    Papanikolaou, D.3    Whiteley, H.E.4    Rosenberg, D.W.5
  • 43
    • 0037229064 scopus 로고    scopus 로고
    • A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity
    • Haigis K.M., and Dove W.F. A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity. Nat. Genet. 33 (2003) 33-39
    • (2003) Nat. Genet. , vol.33 , pp. 33-39
    • Haigis, K.M.1    Dove, W.F.2
  • 44
    • 0030569345 scopus 로고    scopus 로고
    • The possible role of acetyltransferase in the induction of cytogenetic effects by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in cultured Chinese hamster cells
    • Otsuka C., Miura K.F., and Ishidate Jr. M. The possible role of acetyltransferase in the induction of cytogenetic effects by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in cultured Chinese hamster cells. Mutat. Res. 371 (1996) 23-28
    • (1996) Mutat. Res. , vol.371 , pp. 23-28
    • Otsuka, C.1    Miura, K.F.2    Ishidate Jr., M.3
  • 45
    • 12744277582 scopus 로고    scopus 로고
    • Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes
    • Husøy T., Abramsson-Zetterberg L., Ølstorn H.B., Paulsen J.E., and Alexander J. Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes. Mutat. Res. 580 (2005) 111-118
    • (2005) Mutat. Res. , vol.580 , pp. 111-118
    • Husøy, T.1    Abramsson-Zetterberg, L.2    Ølstorn, H.B.3    Paulsen, J.E.4    Alexander, J.5
  • 46
    • 0037228054 scopus 로고    scopus 로고
    • Somatic recombination redux
    • Tischfield J.A., and Shao C. Somatic recombination redux. Nat. Genet. 33 (2003) 5-6
    • (2003) Nat. Genet. , vol.33 , pp. 5-6
    • Tischfield, J.A.1    Shao, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.