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Volumn 72, Issue 5, 2007, Pages 1100-1102

Parawixin1: A spider toxin opening new avenues for glutamate transporter pharmacology

Author keywords

[No Author keywords available]

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; PARAWIXIN1; SPIDER VENOM; UNCLASSIFIED DRUG;

EID: 35548961504     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.041020     Document Type: Short Survey
Times cited : (7)

References (33)
  • 2
    • 0344999542 scopus 로고
    • Concentrative uptake of amino acids by the Ehrlich mouse ascites carcinoma cell
    • Christensen HN and Riggs TR (1952) Concentrative uptake of amino acids by the Ehrlich mouse ascites carcinoma cell. J Biol Chem 194:57-68.
    • (1952) J Biol Chem , vol.194 , pp. 57-68
    • Christensen, H.N.1    Riggs, T.R.2
  • 3
    • 0017439356 scopus 로고
    • The gradient hypothesis and other models of carrier-mediated active transport
    • Crane RK (1977) The gradient hypothesis and other models of carrier-mediated active transport. Rev Physiol Biochem Pharmacol 78:99-159.
    • (1977) Rev Physiol Biochem Pharmacol , vol.78 , pp. 99-159
    • Crane, R.K.1
  • 4
    • 0026539793 scopus 로고
    • +] coupled L-glutamate transporter purified from rat brain is located in glial cell processes
    • +] coupled L-glutamate transporter purified from rat brain is located in glial cell processes. Neuroscience 51:295-310.
    • (1992) Neuroscience , vol.51 , pp. 295-310
    • Danbolt, N.C.1    Storm-Mathisen, J.2    Kanner, B.I.3
  • 5
    • 33846918727 scopus 로고    scopus 로고
    • Spider venoms: A rich source of acylpolyamines and peptides as new leads for CNS drugs
    • Estrada G, Villegas E, and Corzo G (2007) Spider venoms: a rich source of acylpolyamines and peptides as new leads for CNS drugs. Nat Prod Rep 24:145-161.
    • (2007) Nat Prod Rep , vol.24 , pp. 145-161
    • Estrada, G.1    Villegas, E.2    Corzo, G.3
  • 6
    • 0029076899 scopus 로고
    • An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
    • Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, and Amara SG (1995) An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375:599-603.
    • (1995) Nature , vol.375 , pp. 599-603
    • Fairman, W.A.1    Vandenberg, R.J.2    Arriza, J.L.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 10
    • 24344507684 scopus 로고    scopus 로고
    • Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other
    • Grewer C, Balani P, Weidenfeller C, Bartusel T, Tao Z, and Rauen T (2005) Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other. Biochemistry 44:11913-11923.
    • (2005) Biochemistry , vol.44 , pp. 11913-11923
    • Grewer, C.1    Balani, P.2    Weidenfeller, C.3    Bartusel, T.4    Tao, Z.5    Rauen, T.6
  • 13
    • 0028535115 scopus 로고
    • Sodium-coupled neurotransmitter transport: Structure, function and regulation
    • Kanner BI (1994) Sodium-coupled neurotransmitter transport: structure, function and regulation. J Exp Biol 196:237-249.
    • (1994) J Exp Biol , vol.196 , pp. 237-249
    • Kanner, B.I.1
  • 14
    • 33947318986 scopus 로고    scopus 로고
    • The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits
    • Koch HP, Brown RL, and Larsson HP (2007a) The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits. J Neurosci 27:2943-2947.
    • (2007) J Neurosci , vol.27 , pp. 2943-2947
    • Koch, H.P.1    Brown, R.L.2    Larsson, H.P.3
  • 15
    • 34548300005 scopus 로고    scopus 로고
    • Voltage-independent sodium-binding events reported by the 4B-4C loop in the human glutamate transporter excitatory amino acid transporter 3
    • Koch HP, Hubbard JM, and Larsson HP (2007b) Voltage-independent sodium-binding events reported by the 4B-4C loop in the human glutamate transporter excitatory amino acid transporter 3. J Biol Chem 282:24547-24553.
    • (2007) J Biol Chem , vol.282 , pp. 24547-24553
    • Koch, H.P.1    Hubbard, J.M.2    Larsson, H.P.3
  • 16
    • 0347091932 scopus 로고    scopus 로고
    • Glutamate, dopamine, and schizophrenia: From pathophysiology to treatment
    • Laruelle M, Kegeles LS, and bi-Dargham A (2003) Glutamate, dopamine, and schizophrenia: from pathophysiology to treatment. Ann N Y Acad Sci 1003:138-158.
    • (2003) Ann N Y Acad Sci , vol.1003 , pp. 138-158
    • Laruelle, M.1    Kegeles, L.S.2    bi-Dargham, A.3
  • 18
    • 33645847822 scopus 로고    scopus 로고
    • Regulation of astrocytic glutamate transporter expression by Akt: Evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype
    • Li LB, Toan SV, Zelenaia O, Watson DJ, Wolfe JH, Rothstein JD, and Robinson MB (2006) Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype. J Neurochem 97:759-771.
    • (2006) J Neurochem , vol.97 , pp. 759-771
    • Li, L.B.1    Toan, S.V.2    Zelenaia, O.3    Watson, D.J.4    Wolfe, J.H.5    Rothstein, J.D.6    Robinson, M.B.7
  • 19
    • 30044432200 scopus 로고    scopus 로고
    • A dynamic switch between inhibitory and excitatory currents in a neuronal glutamate transporter
    • Melzer N, Torres-Salazar D, and Fahlke C (2005) A dynamic switch between inhibitory and excitatory currents in a neuronal glutamate transporter. Proc Natl Acad Sci U S A 102:19214-19218.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 19214-19218
    • Melzer, N.1    Torres-Salazar, D.2    Fahlke, C.3
  • 20
    • 0033958462 scopus 로고    scopus 로고
    • Glutamate excitotoxicity in a model of multiple sclerosis
    • Pitt D, Werner P, and Raine CS (2000) Glutamate excitotoxicity in a model of multiple sclerosis. Nat Med 6:67-70.
    • (2000) Nat Med , vol.6 , pp. 67-70
    • Pitt, D.1    Werner, P.2    Raine, C.S.3
  • 21
    • 0034688312 scopus 로고    scopus 로고
    • Glutamate release in severe brain ischaemia is mainly by reversed uptake
    • Rossi DJ, Oshima T, and Attwell D (2000) Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403:316-321.
    • (2000) Nature , vol.403 , pp. 316-321
    • Rossi, D.J.1    Oshima, T.2    Attwell, D.3
  • 23
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • Rothstein JD, Martin LJ, and Kuncl RW (1992) Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 326:1464-1468.
    • (1992) N Engl J Med , vol.326 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 25
    • 0036479889 scopus 로고    scopus 로고
    • Aberrant expression of the glutamate transporter excitatory amino acid transporter 1 (EAAT1) in Alzheimer's disease
    • Scott HL, Pow DV, Tannenberg AEG, and Dodd PR (2002) Aberrant expression of the glutamate transporter excitatory amino acid transporter 1 (EAAT1) in Alzheimer's disease. J Neurosci 22:RC206
    • (2002) J Neurosci , vol.22
    • Scott, H.L.1    Pow, D.V.2    Tannenberg, A.E.G.3    Dodd, P.R.4
  • 26
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • Smith T, Groom A, Zhu B, and Turski L (2000) Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat Med 6:62-66.
    • (2000) Nat Med , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Turski, L.4
  • 29
    • 34249935610 scopus 로고    scopus 로고
    • Glutamate and monoamine transporters: New visions of form and function
    • Torres GE and Amara SG (2007) Glutamate and monoamine transporters: new visions of form and function. Curr Opin Neurobiol 17:304-312.
    • (2007) Curr Opin Neurobiol , vol.17 , pp. 304-312
    • Torres, G.E.1    Amara, S.G.2
  • 30
    • 33746064534 scopus 로고    scopus 로고
    • Intersubunit interactions in EAAT4 glutamate transporters
    • Torres-Salazar D, and Fahlke C (2006) Intersubunit interactions in EAAT4 glutamate transporters. J Neurosci 26:7513-7522.
    • (2006) J Neurosci , vol.26 , pp. 7513-7522
    • Torres-Salazar, D.1    Fahlke, C.2
  • 31
    • 0029142729 scopus 로고
    • Ion fluxes associated with excitatory amino acid transport
    • Wadiche JI, Amara SG, and Kavanaugh MP (1995) Ion fluxes associated with excitatory amino acid transport. Neuron 15:721-728.
    • (1995) Neuron , vol.15 , pp. 721-728
    • Wadiche, J.I.1    Amara, S.G.2    Kavanaugh, M.P.3
  • 32
    • 0034967684 scopus 로고    scopus 로고
    • Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1
    • Watzke N, Bamberg E, and Grewer C (2001) Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1. J Gen Physiol 117:547-562.
    • (2001) J Gen Physiol , vol.117 , pp. 547-562
    • Watzke, N.1    Bamberg, E.2    Grewer, C.3
  • 33
    • 0029860263 scopus 로고    scopus 로고
    • Flux coupling in a neuronal glutamate transporter
    • Zerangue N and Kavanaugh MP (1996) Flux coupling in a neuronal glutamate transporter. Nature 383:634-637.
    • (1996) Nature , vol.383 , pp. 634-637
    • Zerangue, N.1    Kavanaugh, M.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.