Gastric secretion

Current Opinion in Gastroenterology

Volumn 21, Issue 6, 2005, Pages 636-643

  Schubert, Mitchell L ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acid secretion; Enteric nervous system; Gastrin; Histamine; Neuropeptide; Parietal cell; Somatostatin

Indexed keywords

BENZODIAZEPINE; BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; CHOLECYSTOKININ; DC 3287; DIAZEPAM; DICLOFENAC; EPIDERMAL GROWTH FACTOR; GALANIN; GASTRIN; GHRELIN; GONADORELIN; HISTAMINE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; OREXIN; PARTIAL AGONIST; PIROXICAM; PROTEINASE; PROTON PUMP; PROTON PUMP INHIBITOR; RO 54864; SOMATOSTATIN; STOMACH SECRETION INHIBITOR; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

AUTOCRINE EFFECT; BACTERIAL OVERGROWTH; CALCIUM ABSORPTION; CALCIUM CELL LEVEL; CYTOPLASM; DEFENSE MECHANISM; GASTRITIS; HELICOBACTER PYLORI; HISTAMINE METABOLISM; HISTAMINE RELEASE; HORMONE RELEASE; HUMAN; INTESTINE INFECTION; IRON ABSORPTION; NONHUMAN; PARACRINE SIGNALING; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN CONFORMATION; PROTEIN TRANSPORT; REVIEW; STOMACH ACID SECRETION; STOMACH CANCER; STOMACH EROSION; STOMACH MUCOSA; STOMACH PARIETAL CELL; STOMACH ULCER;

GASTRIC ACID; GASTRINS; HISTAMINE; HUMANS; PARIETAL CELLS, GASTRIC; PEPTIDE HORMONES; SOMATOSTATIN;

EID: 27644453081     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mog.0000181713.89281.14     Document Type: Review

References (57)

1. - secretion: the role of brain-gut axis. Eur J Pharmacol 2004; 499:15-27. This is a comprehensive review of the neuroendocrine regulation of acid secretion, mainly from a historical viewpoint.
2. Gyires K. Neuropeptides and gastric mucosal homeostasis. Curr Top Med Chem 2004; 4:63-73.
3. Mazda T, Yamamoto H, Fujimura M, Fujimiya M. Gastric distension-induced release of 5-HT stimulates c-fos expression in specific brain nuclei via 5-HT3 receptors in conscious rats. Am J Physiol Gastrointest Liver Physiol 2004; 287:G228-G235. Gastric distension releases serotonin from enterochromaffin cells that activate 5-hydroxytryptamine 3 (5-HT3) receptors on vagal afferents, leading to neuron activation in the central nervous sytem.
4. Yamada H, Takahashi N, Tanno S, et al. A selective orexin-1 receptor antagonist, SB334867, blocks 2-DG-induced gastric acid secretion in rats. Neurosci Lett 2005; 376:137-142. Orexin receptor-1 antagonist was used to demonstrate that orexin-A contributes to the cephalic phase of acid secretion.
5. Aly A, Shulkes A, Baldwin GS. Gastrins, cholecystokinins and gastrointestinal cancer. Biochim Biophys Acta 2004; 1704:1-10. This is a nice review of the proliferative effects of gastrin
6. Rehfeld JF, Bundgaard JR, Goetze JP, et al. Naming progastrin-derived peptides. Regul Pept 2004; 120:177-183. This paper discusses the structure, processing, and naming of progastrin-derived peptides.
7. Dockray G, Dimaline R, Varro A. Gastrin: old hormone, new functions. Pflugers Arch 2005; 449:344-355. This is an excellent review of the processing, release, binding, and actions of gastrin.
8. 2 production. Br J Pharmacol 2005; 144:338-348.
9. Beales ILP. Gastrin and interleukin-1 β stimulate growth factor secretion from cultured rabbit gastric parietal cells. Life Sci 2004; 75:2983-2995.
10. Paterson AC, Lockhart SM, Baker J, et al. Identity and regulation of stored and secreted progastrin-derived peptides in sheep. Endocrinology 2004; 145: 5129-5140.
11. He H, Shehan BP, Barnham KJ, et al. Biological activity and ferric ion binding of fragments of glycine-extended gastrin. Biochemistry 2004; 43: 11853-11861.
12. Pannequin J, Kovac S, Tantiongco JP, et al. A novel effect of bismuth ions: selective inhibition of the biological activity of glycine-extended gastrin. J Biol Chem 2004; 279:2453-2460.
13. Reeve JR Jr, Liddle RA, McVey DC, et al. Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties. Am J Physiol Gastrointest Liver Physiol 2005; 287:G326-G333.
14. 1 receptor in the regulation of gastrin release. J Pharmacol Exp Ther 2004; 310:477-487.
15. Vuyyuru L, Schubert ML, Harrington L, et al. Dual inhibitory pathways link antral somatostatin and histamine secretion in human, dog, and rat stomach. Gastroenterology 1995; 109:1566-1574.
16. 3 receptors, inhibits somatostatin and stimulates acid secretion in isolated mouse stomach. Gastroenterology 1997; 113:1545-1552.
17. 3 receptor: evidence for multiple isoforms. J Neurochem 2004; 90:1331-1338.
18. Nakamura E, Kataoka T, Furutani K, et al. Lack of histamine alters gastric mucosal morphology: comparison of histidine decarboxylase-deficient and mast cell-deficient mice. Am J Physiol Gastrointest Liver Physiol 2004; 287:G1053-G1061. Histidine decarboxylase-deficient mice exhibit no gastric mucosal histamine synthesis and display hypoacidity with resultant hypergastrinemia. Hypergastrinemia leads to hyperplasia of the oxyntic mucosa with increased numbers of parietal and ECL cells
19. Miyaoka Y, Kadowaki Y, Ishihara S, et al. Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages. Oncogene 2004; 23:3572-3579.
20. Brzozowski T, Konturek PC, Konturek SJ, et al. Exogenous and endogenous ghrelin in gastroprotection against stress-induced gastric damage. Regul Pept 2004; 120:39-51.
21. Lin E, Gletsu N, Fugate K, et al. The effects of gastric surgery on systemic ghrelin levels in the morbidly obese. Arch Surg 2004; 139:780-784.
22. Wei W, Wang GY, Qi X, et al. Characterization and regulation of the rat and human ghrelin promoters. Endocrinology 2005; 146:1611-1625.
23. Broglio F, Gottero C, Van Koetsveld P, et al. Acetylcholine regulates ghrelin secretion in humans. J Clin Endocrinol Metab 2004; 89:2429-2433.
24. Lippl F, Kircher F, Erdmann J, et al. Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach. Regul Pept 2004; 119:93-98.
25. Cummings DE. Helicobacter pylori and ghrelin: interrelated players in body-weight regulation? Am J Med 2004; 117:436-439.
26. Isomoto H, Nakazato M, Ueno H, et al. Low plasma ghrelin levels in patients with Helicobacter pylori associated gastritis. Am J Med 2004; 117:429-432. Infection with H. pylori is associated with decreased plasma ghrelin concentrations. Furthermore, ghrelin levels correlated inversely with severity of gastritis and were the lowest in patients with corpus gastritis.
27. Osawa H, Nakazato M, Date Y, et al. Impaired production of gastric ghrelin in chronic gastritis associated with Helicobacter pylori. J Clin Endocrinol Metab 2005; 90:10-16. See [26].
28. Nwokolo CU, Freshwater DA, O'Hare P, Randeva HS. Plasma ghrelin following cure of Helicobacter pylori. Gut 2003; 52:637-640.
29. Tatsuguchi A, Miyake K, Gudis K, et al. Effect of Helicobacter pylori infection on ghrelin expression in human gastric mucosa. Am J Gastroenterol 2004; 99:2121-2127.
30. Piqueras L, Martinez V. Role of somatostatin receptors on gastric acid secretion in wild-type and somatostatin receptor type 2 knockout mice. Naunyn Schmiedebergs Arch Pharmacol 2004; 370:510-520.
31. 2)-mediated effects of endogenous somatostatin on exocrine and endocrine secretion of the rat stomach. Br J Pharmacol 2005; 144:416-421.
32. Zavros Y, Kao JY, Merchant JL. Inflammation and cancer: III. Somatostatin and the innate immune system. Am J Physiol Gastrointest Liver Physiol 2004; 286:G698-G701.
33. Zavros Y, Merchant JL. Modulating the cytokine response to treat Helicobacter gastritis. Biochem Pharmacol 2005; 69:365-371.
34. 2A receptor in the regulation of gastric somatostatin release. J Pharmacol Exp Ther 2004; 309:804-815.
35. 2A receptor gene expression and function. J Pharmacol Exp Ther 2004; 311:180-189.
36. Dalm VA, Van Hagen PM, De Krijger RR, et al. Distribution pattern of somatostatin and cortistatin mRNA in human central and peripheral tissues. Clin Endocrinol (Oxf) 2004; 60:625-629.
37. Blaser MJ, Atherton JC. Helicobacter pylori persistence: biology and disease. J Clin Invest 2004; 113:321-333. This is a nice review of H. pylori virulence factors and host responses, and their interaction.
38. Iijima K, Ohara S, Koike T, et al. Gastric acid secretion of normal Japanese subjects in relation to Helicobacter pylori infection, aging, and gender. Scand J Gastroenterol 2004; 39:709-716.
39. Joseph IM, Kirschner D. A model for the study of Helicobacter pylori interaction with human gastric acid secretion. J Theor Biol 2004; 228:55-80.
40. Newton JL, James OFW, Williams GV, Allen A. The diurnal profile of gastric pepsin activity is reduced with Helicobacter pylori infection. Dig Dis Sci 2004; 49:1103-1108.
41. Brzozowski T, Konturek PC, Moran AP, et al. Involvement of capsaicin-sensitive afferent nerves and cholecystokinin 2/gastrin receptors in gastroprotection and adaptation of gastric mucosa to Helicobacter pylori-lipopolysaccharide. J Pharmacol Exp Ther 2004; 310:116-125.
42. Gillen D, Wirz A, McColl KEL. Helicobacter pylori eradication releases prolonged increased acid secretion following omeprazole treatment. Gastroenterology 2004; 126:980-988. Rebound acid secretion following withdrawal of omeprazole occurs in H. pylori-negative, but not -positive, individuals.
43. Güliter S, Kandilci U. The effect of Helicobacter pylori eradication on gastroesophageal reflux disease. J Clin Gastroenterol 2004; 38:750-755.
44. Inoue H, Imoto I, Taguchi Y, et al. Reflux esophagitis after eradication of Helicobacter pylori is associated with the degree of hiatal hernia. Scand J Gastroenterol 2004; 39:1061-1065.
45. Piqueras L, Taché Y, Martinez V. Peripheral PACAP inhibits gastric acid secretion through somatostatin release in mice. Br J Pharmacol 2004; 142:67-78.
46. Stepan V, Pailisawasdi N, Ramamoorthy S, Todisco A. The Akt and MAPK signal transduction pathways regulate growth factor actions in isolated gastric parietal cells. Gastroenterology 2004; 127:1150-1161.
47. Vongthavaravat V, Saymeh LA, Mesiya SA, et al. Functional interaction between transforming growth factor α and capsaicin-sensitive sensory neurons in the rat stomach. Regul Pept 2004; 119:163-167. A feedback pathway exists whereby TGF-α released from parietal cells activates afferent CGRP neurons that inhibit TGF-α secretion, perhaps by stimulation of somatostatin secretion.
48. Piqueras L, Taché Y, Martinez V. Galanin inhibits gastric acid secretion through a somatostatin-independent mechanism in mice. Peptides 2004; 25:1287-1295.
49. Berg A, Redeen S, Ericson AC, Sjöstrand SE. Nitric oxide: an endogenous inhibitor of gastric acid secretion in isolated human gastric glands. BMC Gastroenterol 2005; 4:16. Nitric oxide synthase inhibitors were used to demonstrate that endogenous nitric oxide inhibits gastric acid secretion in isolated human oxyntic glands.
50. Chen L, Sun XD, Zhao J, et al. Distribution, cloning and sequencing of GnRH, its receptor, and effects of gastric acid secretion of GnRH analogue in gastric parietal cells of rats. Life Sci 2005; 76:1351-1365.
51. Salvatella MA, Rossi I, Del Valle JC, et al. Inhibition of acid secretion by the nonsteroidal anti-inflammatory drugs diclofenac and piroxicam in isolated gastric glands: analysis of a multifocal mechanism. Am J Physiol Gastrointest Liver Physiol 2004; 286:G711-G721.
52. Kato Y, Fukamachi H, Takano-Maruyama M, et al. Reduction of SNAP25 in acid secretion defect of Foxl1-|- gastric parietal cells. Biochem Biophys Res Commun 2004; 320:766-772.
53. Crothers JM Jr, Asano S, Kimura T, et al. Contribution of oligosaccharides to protection of H,K-ATPase β-subunit against trypsinolysis. Electrophoresis 2004; 25:2586-2592.
54. + ATPase endocytosis. Gastroenterology 2004; 127:145-154.
55. +-ATPase in vivo. Biochem Pharmacol 2004; 68:2117-2127. Restoration of acid secretion after treatment with covalently bound proton pump inhibitors depends on protein turnover and on reversal of inhibition by reducing agents such as glutathione.
56. Shin JM, Sachs G. Restoration of acid secretion following treatment with proton pump inhibitors. Gastroenterology 2002; 123:1588-1597.
57. Ostuni MA, Marazova K, Peranzi G, et al. Functional characterization and expression of PBR in rat gastric mucosa: stimulation of chloride secretion by PBR ligands. Am J Physiol Gastrointest Liver Physiol 2004; 286: G1069-G1080.