Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome

Clinical Microbiology Reviews

Volumn 20, Issue 4, 2007, Pages 622-659

  Riordan, Terry ^a,b  

^a ROYAL DEVON AND EXETER NHS FOUNDATION TRUST   (United Kingdom)

^b Microbiology Department   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; CEFOTAXIME; CEFTAZIDIME; CLINDAMYCIN; ERYTHROMYCIN; GENTAMICIN; HEPARIN; METRONIDAZOLE; PENICILLIN G; STEROID; SULTAMICILLIN; TIMENTIN; VIRULENCE FACTOR;

ANTIBIOTIC THERAPY; BACTERIAL VIRULENCE; BRAIN ABSCESS; CEREBRAL SINUS THROMBOSIS; DIAGNOSTIC APPROACH ROUTE; DIFFERENTIAL DIAGNOSIS; DISEASE PREDISPOSITION; DISEASE TRANSMISSION; FUSOBACTERIUM NECROPHORUM; HUMAN; INCIDENCE; INFECTIOUS MONONUCLEOSIS; LEMIERRE SYNDROME; MENINGITIS; NONHUMAN; OXYGEN THERAPY; PATHOGENESIS; RADIOLOGY; REVIEW; RISK FACTOR; SEPTICEMIA; SEX RATIO; SYMPTOMATOLOGY; THROMBOPHILIA; THROMBOPHLEBITIS; TONSILLITIS;

ADOLESCENT; ADULT; ANIMALS; ANTI-BACTERIAL AGENTS; FEMALE; FUSOBACTERIUM INFECTIONS; FUSOBACTERIUM NECROPHORUM; HUMANS; MALE; SYNDROME;

ANIMALIA; FUSOBACTERIUM NECROPHORUM;

EID: 35448988592     PISSN: 08938512     EISSN: None     Source Type: Journal    
DOI: 10.1128/CMR.00011-07     Document Type: Review

References (403)

1. Aas, J. A., B. J. Paster, L. N. Stokes, I. Olsen, and F. E. Dewhirst. 2005. Defining the normal bacterial flora of the oral cavity. J. Clin. Microbiol. 43:5721-5732.
2. Abele-Horn, M., P. Emmerling, and J. F. E. Mann. 2001. Lemierre's syndrome with spondylitis and pulmonary and gluteal abscesses associated with Mycoplasma pneumoniae pneumonia. Eur. J. Clin. Microbiol. Infect. Dis. 20:263-266.
3. Abt, I. A. 1932. Postanginal sepsis. J. Pediatr. 1:8-15.
4. Adams, J., T. Capistrant, K. Crossley, R. Johanssen, and S. Liston. 1983. Fusobacterium necrophorum septicaemia. JAMA 250:35. (Letter.)
5. Agarwal, R., P. S. Arunachalam, and D. A. Bosman. 2000. Lemierre's syndrome: a complication of acute oropharyngitis. J. Laryngol. Otol. 114:545-547.
6. Ahkee, S., L. Srinatha, A. Huang, M. J. Raff, and J. A. Ramirez. 1994. Lemierre's syndrome: postanginal sepsis due to anaerobic oropharyngeal infection. Ann. Otol. Rhinol. Laryngol. 103:208-210.
7. Albertyn, L. E., and M. K. Alcock. 1987. Diagnosis of internal jugular vein thrombosis. Radiology 162:505-508.
8. Ali, M. T., P. Jain, and G. Narayanswami. 2003. Lemierre's syndrome: sepsis complicating a dental procedure. Chest 124:300.
9. Aliyu, S. H., P. F. K. Yong, M. J. Newport, H. Zhang, R. K. Marriott, M. D. Curran, and H. Ludlam. 2005. Molecular diagnosis of Fusobacterium necrophorum infection (Lemierre's syndrome). Eur. J. Clin. Microbiol. Infect. Dis. 24:226-229.
10. Aliyu, S. H., R. K. Marriott, M. D. Curran, S. Parmar, N. Bentley, N. M. Brown, J. S. Brazier, and H. Ludlam. 2004. Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice. J. Med. Microbiol. 53:1029-1035.
11. Alston, J. M. 1955. Necrobacillosis in Great Britain. Br. Med. J. 1955:1524-1528.
12. Alvarez, A., and J. R. Schreiber. 1995. Lemierre's syndrome in adolescent children - anaerobic sepsis with internal jugular vein thrombophlebitis following pharyngitis. Pediatrics 96:354-359.
13. Amoako, K. K., Y. Goto, and T. Shinjo. 1993. Comparison of extracellular enzymes of Fusobacterium necrophorum subsp. necrophorum and Fusobacterium necrophorum subsp. funduliforme. J. Clin. Microbiol. 31:2244-2247.
14. Andrianakis, I. A., A. N. Kotanidou, M. T. Pitaridis, G. J. Saroglou. D. N. Exarhos, C. S. Roussos, and I. P. Bellenis. 2002. Life-threatening bilateral empyema and mediastinitis complicating infectious mononucleosis. Intens. Care Med. 28:663-664.
15. Aoki, M., R. C. Noble, E. J. Scott, and G. V. Osetinsky. 1993. Lemierre's syndrome caused by Fusobacterium necrophorum: a case report. J. Ky. State Med. Assoc. 91:141-142.
16. Applebaum, P. C., S. K. Spangler, and M. R. Jacobs. 1990. β-Lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers. Antimicrob. Agents Chemother. 34:1546-1550.
17. Armstrong, A. W., K. Spooner, and J. W. Sanders. 2000. Lemierre's syndrome. Curr. Infect. Dis. Report. 2:168-173.
18. Auber, A. E., and P. A. Mancuso. 2000. Lemierre syndrome: magnetic resonance imaging and computed tomographic appearance. Mil. Med. 165:638-640.
19. Bach, M. C., J. H. Roediger, and H. M. Rinder. 1988. Septic anaerobic jugular phlebitis with pulmonary embolism: problems in management. Rev. Infect. Dis. 10:424-427.
20. Bader-Meunier, B., G. Pinto, M. Tardieu, D. Pariente, S. Bobin, and J.-P. Dommergues. 1994. Mastoiditis, meningitis and venous sinus thrombosis caused by Fusobacterium necrophorum. Eur. J. Pediatr. 153:339-341.
21. Baker, A. S., and W. W. Montgomery. 1987. Oropharyngeal space infections, p. 227-265. In J. S. Remington and M. N. Sevartz (ed.), Current clinical topics in infectious diseases, vol. 8. McGraw-Hill, New York, NY.
22. Bang, B. 1890. Om Aarsagen til local Nekrose. Maanedsskrift Dyrlæger 2:235-259.
23. Bang, B. L. F. 1897. Die aetiologie des seuchenhaften (infectiosen) verwerfens. Z. Thiermedizin 1:241-278.
24. Baquero, F., and M. Reig. 1992. Resistance of anaerobic bacteria to antimicrobial agents in Spain. Eur. J. Clin. Microbiol. Infect. Dis. 11:1016-1020.
25. Bartell, J. M. 2001. Lemierre's syndrome. Wisc. Med. J. Proceedings of the 2001 Annual Meeting of the American College of Physicians. http://www.acponline.org/chapters/wi/associates/2001/vignette18.htm.
26. Bartlett, J. G., A. B. Onderdonk, E. Drude, C. Goldstein, M. Anderka, S. Alpert, and W. M. McCormack. 1977. Quantitative bacteriology of the vaginal flora. J. Infect. Dis. 136:271-277.
27. Bartlett, J. G., and S. L. Gorbach. 1976. Anaerobic infections of the head and neck. Otolaryng. Clin. N. Am. 9:655-678.
28. Bartlett, J. G., and S. M. Finegold. 1974. Anaerobic infections of the lung and pleural space. Am. Rev. Respir. Dis. 110:56-77.
29. Batty, A., and M. W. D. Wren. 2005. Prevalence of Fusobacterium necrophorum and other upper respiratory tract pathogens isolated from throat swabs. Br. J. Biomed. Sci. 62:66-70.
30. Batty, A., M. W. D. Wren, and M. Gal. 2005. Fusobacterium necrophorum as the cause of recurrent sore throat: comparison of isolates from persistent sore throat syndrome and Lemierre's disease. J. Infect. 51:299-306.
31. Beerens, H. 1954. Procédé de différenciation entre Spherophorus necrophorus (Schmorl 1891) et Spherophorus funduliformis (Hallé 1898). Ann. Inst. Pasteur Paris 86:384-386.
32. Beldman, T. F. J., H. A. Teunisse, and T. J. Schouten. 1997. Septic arthritis of the hip by Fusobacterium necrophorum after tonsillectomy: a form of Lemierre syndrome? Eur. J. Pediatr. 156:856-857.
33. Bennett, K. W., and A. Eley. 1993. Fusobacteria: new taxonomy and related diseases. J. Med. Microbiol. 39:246-254.
34. Bentham, J. R., A. J. Pollard, C. A. Milford, P. Anslow, and M. G. Pike. 2004. Cerebral infarct and meningitis secondary to Lemierre's syndrome. Pediatr. Neurol. 30:281-283.
35. Bergeron, M. G., J. Robert, and D. Beauchamp. 1993. Pharmacodynamics of antibiotics in fibrin clots. J. Antimicrob. Chemother. 31(Suppl. D):113-136.
36. Bhattacharya, S., S. A. Livsey, M. Wiselka, and S. S. Bukhari. 2005. Fusobacteriosis presenting as community acquired pneumonia. J. Infect. 50:236-239.
37. Bilfinger, T. V., C. K. Hayden, K. T. Oldham, and T. E. Lobe. 1986. Pyogenic liver abscesses in nonimmunocompromised children. South Med. J. 79:37-40.
38. Bisno, A. L., M. A. Gerber, J. M. Gwaltney, Jr., E. L. Kaplan, and R. H. Schwartz. 2002. Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Clin. Infect. Dis. 35:113-125.
39. Bliss, S. J., S. A. Flanders, and S. Saint. 2004. A pain in the neck. N. Engl. J. Med. 350:1037-1042.
40. Blomquist, I. K., and A. S. Bayer. 1988. Life-threatening deep fascial space infections of the head and neck. Infect. Dis. Clin. N. Am. 2:237-264.
41. Boharas, S. 1943. Postanginal sepsis. Arch. Intern. Med. 71:844-853.
42. Bourbeau, P. P. 2003. Role of the microbiology laboratory in diagnosis and management of pharyngitis. J. Clin. Microbiol. 41:3467-3472.
43. Bourgault, A.-M., F. Lamothe, P. Dolcé, L. Saint-Jean, and P. Saint-Antoine. 1997. Fusobacterium bacteremia: clinical experience with 40 cases. Clin. Infect. Dis. 25(Suppl. 2):S181-S183.
44. Bouvier, D. P., R. D. Armstrong, D. M. Bradshaw, and R. E. Hoenzsch. 1995. Fusobacterium necrophorum septicaemia without a primary focus. South. Med. J. 78:1521-1522.
45. Boyanova, L., V. Djambazov, G. Gergova, D. Iotov, D. Petrov, D. Osmanliev, Z. Minchev, and I. Mitov. 2004. Anaerobic microbiology in 198 cases of pleural empyema: a Bulgarian study. Anaerobe 10:261-267.
46. Boz, G. A., S. Iskender, R. Caylan, K. Aydin, and I. Koksal. 2005. A case of Lemierre's syndrome following Epstein-Barr virus infection. Anaerobe 11:185-187.
47. Braun, I. F., J. C. Hoffman, Jr., J. A. Malko, R. I. Pettigrew, W. Daniels, and P. C. Davis. 1985. Jugular venous thrombosis: MR imaging. Radiology 157:357-360.
48. Brazier, J. S. 1986. Yellow fluorescence of fusobacteria. Lett. Appl. Microbiol. 2:125-126.
49. Brazier, J. S. 2002. Fusobacterium necrophorum infections in man. Rev. Med. Microbiol. 13:141-149.
50. Brazier, J. S. 2006. Human infections with Fusobacterium necrophorum. Anaerobe. 12:165-172.
51. Brazier, J. S., D. M. Citron, and E. J. C. Goldstein. 1991. A selective medium for Fusobacterium spp. J. Appl. Bacteriol. 71:343-346.
52. Brazier, J. S., V. Hall, E. Yusuf, and B. I. Duerden. 2002. Fusobacterium necrophorum infections in England and Wales 1990-2000. J. Med. Microbiol. 51:269-272.
53. Broberg, T., A. Murr, and N. Fischbein. 1999. Devastating complications of acute pediatric bacterial sinusitis. Otolaryng. Head Neck Surg. 120:575-579.
54. Brocard, H., and C. Guibé. 1957. Les septicémies a Bacillus funduliformis. Rev. Praticien. 7:1285-1300.
55. Brook, I. 1981. Aerobic and anaerobic bacteriology of chronic mastoiditis in children. Am. J. Dis. Child. 135:478-479.
56. Brook, I. 1992. Aerobic and anaerobic bacteriology of intracranial abscesses. Pediatr. Neurol. 8:210-214.
57. Brook, I. 1993. Infections caused by beta-lactamase-producing Fusobacterium spp. in children. Pediatr. Infect. Dis. J. 12:532-533.
58. Brook, I. 2003. Microbiology and management of deep facial infections and Lemierre syndrome. J. Otorhinolaryngol. Relat. Spec. 65:117-120.
59. Brook, I. 2003. Microbiology and management of periodontal infections. Gen. Dent. 51:424-428.
60. Brook, I. 2005. The association of anaerobic bacteria with infectious mononucleosis. Anaerobe 11:308-311.
61. Brook, I. 2005. The role of anaerobic bacteria in acute and chronic mastoiditis. Anaerobe 11:252-257.
62. Brook, I., and E. H. Frazier. 1996. Microbiology of mediastinitis. Arch. Intern. Med. 156:333-336.
63. Brook, I., and P. A. Foote, Jr. 1990. Microbiology of "normal tonsils." Ann. Oto. Rhinol. Laryngol. 99:980-983.
64. Brook, I., and P. Burke. 1992. The management of acute, serous and chronic otitis media: the role of anaerobic bacteria. J. Hosp. Infect. 22(Suppl. A):75-87.
65. Brook, I., and S. M. Finegold. 1979. Bacteriology of chronic otitis media. JAMA 241:487-488.
66. Brook, I., P. Yocum, and E. M. Friedman. 1981. Aerobic and anaerobic bacteria in tonsils of children with recurrent tonsillitis. Ann. Otol. Rhinol. Laryngol. 90:261-263.
67. Brook, I., and K. Shah. 2001. Bacteriology of adenoids and tonsils in children with recurrent adenotonsillitis. Ann. Otol. Rhinol. Laryngol. 110:844-848.
68. Brook, I., P. Yocum, and K. Shah. 1980. Surface vs core-tonsillar aerobic and anaerobic flora in recurrent tonsillitis. JAMA 244:1696-1698.
69. Brook, I., S. F. Anthony, and S. M. Finegold. 1978. Aerobic and anaerobic bacteriology of acute otitis media in children. J. Pediatr. 92:13-15.
70. Brown, R., H. G. Lough, and I. R. Poxton. 1997. Phenotypic characteristics and lipopolysaccharides of human and animal isolates of Fusobacterium necrophorum. J. Med. Microbiol. 46:873-878.
71. Bullen, J. J., H. J. Rogers, P. B. Spalding, and C. G. Ward. 2005. Iron and infection: the heart of the matter. FEMS Immunol. Med. Microbiol. 43:325-330.
72. Busch, D. F., L. A. Kureshi, V. L. Sutter, and S. M. Finegold. 1976. Susceptibility of respiratory tract anaerobes to orally administered penicillins and cephalosporins. Antimicrob. Agents Chemother. 10:713-720.
73. Carpenter, J. P., G. A. Holland, R. A. Baum, R. S. Owen, J. T. Carpenter, and C. Cope. 1993. Magnetic resonance venography for the detection of deep venous thrombosis: comparison with contrast venography and duplex Doppler ultrasonography. J. Vasc. Surg. 18:734-741.
74. Carrie, S., and P. A. Fenton. 1994. Necrobacillosis - an unusual case of pharyngotonsillitis. J. Laryngol. Otol. 108:1097-1098.
75. Cartwright, K. A., D. M. Jones, A. J. Smith, J. M. Stuart, E. B. Kaczmarski, and S. R. Palmer. 1991. Influenza A and meningococcal disease. Lancet 338:554-557.
76. Cartwright, K. A. V. 1995. Meningococcal carriage and disease, p. 115-146. In K. A. V. Cartwright (ed.), Meningococcal disease, vol. 5. John Wiley & Sons, New York, NY.
77. Celig, D. M., and P. C. Schreckenberger. 1991. Clinical evaluation of the RapID-ANA II panel for identification of anaerobic bacteria. J. Clin. Microbiol. 29:457-462.
78. Celikel, T. H., and P. P. Muthuswamy. 1984. Septic pulmonary emboli secondary to internal jugular vein phlebitis (postanginal sepsis) caused by Eikenella corrodens. Am. Rev. Respir. Dis. 130:510-513.
79. Chalstrey, S. E., H. O. L. Williams, and G. Reilly. 1992. Necrobacillosis - an unusual cause of cervical abscess. J. Laryngol. Otol. 106:374-375.
80. Chan, E. D., M. H. Hermanoff, and E. Connick. 1999. Lemierre's syndrome: review of the English literature over the past 25 years. Clin. Pulm. Med. 6:333-338.
81. Chand, D. H., R. C. Brady, and J. J. Bissler. 2001. Hemolytic uremic syndrome in an adolescent with Fusobacterium necrophorum bacteremia. Am. J. Kidney Dis. 37:1-4.
82. Chang, P. S., J. P. Harris, N. Bhumbra, M. Puczynski, N. Kherrallah, T. J. Lewis, N. Shilen, and S. Rana. 2006. Index of suspicion. Pediatr. Rev. 27:73-78.
83. Charles, K., W. R. Flinn, and D. G. Neschis. 2005. Lemierre's syndrome: a potentially fatal complication that may require vascular surgical intervention. J. Vasc. Surg. 42:1023-1025.
84. Chemlal, K., I. Caby, N. Memain, D. Aubert, and F. Bruneel. 2000. Syndrome de Lemierre dû à Streptococcus intermedius: une association inhabituelle. Presse Méd. 29:1601-1602.
85. Chirinos, J. A., D. M. Lichtstein, J. Garcia, and L. J. Tamariz. 2002. The evolution of Lemierre syndrome. Report of 2 cases and review of the literature. Medicine 81:458-465.
86. Cho, Y. P., S.-J. Choi, B. H. Jung, J.-W. Hwang, M. S. Han, Y. H. Kim, T.-W. Kwon, and S. G. Lee. 2006. Lemierre's syndrome in a patient with antiphospholipid syndrome. Ann. Vasc. Surg. 20:274-277.
87. Chow, A. W. 1992. Life-threatening infections of the head and neck. Clin. Infect. Dis. 14:991-1004.
88. Chow, A. W., S. M. Roser, and F. A. Brady. 1978. Orofacial odontogenic infections. Ann. Intern. Med. 88:392-402.
89. Ciccone, A., P. Canhao, F. Falcao, J. M. Ferro, and R. Sterzi. 2004. Thrombolysis for cerebral vein and dural sinus thrombosis. Cochrane Database Syst. Rev. 1:D003693.
90. Citron, D. M. 2002. Update on the taxonomy and clinical aspects of the genus Fusobacterium. Clin. Infect. Dis. 35(Suppl. 1):S22-S27.
91. Civen, R., H. Jousimies-Somer, M. Marina, L. Borenstein, H. Shah, and S. M. Finegold. 1995. A retrospective review of cases of anaerobic empyema and update of bacteriology. Clin. Infect. Dis. 20(Suppl. 2):S224-S229.
92. Clarke, M. G., N. J. Kennedy, and K. Kennedy. 2003. Serious consequences of a sore throat. Ann. R. Coll. Surg. Engl. 85:242-244.
93. Claus, H. C. 1931. Über 100 Fälle von Septico-Pyämie nach Angina. Med. Klin. Wochenschr. Praktische Árzte 35:1269-1271.
94. Conrads, G., M. C. Claros, D. M. Citron, C. V. Merriam, Y. Warren, and E. J. Goldstein. 2002. 16S-23S rDNA internal transcribed spacer sequences for analysis of the phylogenetic relationships among species of the genus Fusobacterium. Int. J. Syst. Evol. Microbiol. 52:493-499.
95. Constantin, J.-M., J.-P. Mira, R. Guerin, S. Cayot-Constantin, O. Lesens, F. Gourdon, J.-P. Romaszko, P. Linval, H. Laurichesse, and J.-E. Bazin. 2006. Lemierre's syndrome and genetic polymorphisms: a case report. BMC Infect. Dis. 17:115.
96. Cook, R. J., R. W. Ashton, G. L. Aughenbaugh, and J. H. Ryu. 2005. Septic pulmonary embolism. Presenting features and clinical course of 14 patients. Chest 128:162-166.
97. Cosgrove, E. F., S. M. Colodny, and R. R. Pesce. 1993. Adult respiratory distress syndrome as a complication of postanginal sepsis. Chest 103:1628-1629.
98. Courmont, P., and A. Cade. 1900. Sur une septico-pyohémie de l'homme simulant la peste et causée par un strepto-bacille anaérobic. Arch. de Méd. Exp. 12:393-418.
99. Coyle-Dennis, J. E., and L. H. Lauerman. 1979. Correlations between leukocidin production and virulence of two isolates of Fusobacterium necrophorum. Am. J. Vet. Res. 40:274-276.
100. Cron, R. Q., and K. H. Webb. 1995. Necrobacillosis: an unusual cause of purulent otitis media and sepsis. Pediatr. Emerg. Care 11:379-380.
101. Croucher, S. C., A. P. Houston, C. E. Bayliss, and R. J. Turner. 1983. Bacterial populations associated with different regions of the human colon wall. Appl. Environ. Microbiol. 45:1025-1033.
102. Cunningham, J. S. 1930. Human infection with Actinomyces necrophorus. Arch. Pathol. 9:843-868.
103. Dack, G. M. 1940. Non-sporeforming anaerobic bacteria of medical importance. Bacteriol. Rev. 4:227-259.
104. Dagan, R., and K. R. Powell. 1987. Postanginal sepsis following infectious mononucleosis. Arch. Intern. Med. 147:1581-1583.
105. Dalamaga, M., K. Karmaniolas, C. Chavelas, S. Liatis, H. Matekovits, and I. Migdalis. 2003. Fusobacterium necrophorum septicaemia following Epstein Barr Virus infectious mononucleosis. Anaerobe 9:285-287.
106. de Lima, J. E., Jr., and M. Levin. 2003. Lemierre's syndrome: post-anginal septicaemia. Pediatr. Radiol. 33:281-283.
107. Dellamonica, P., and E. Bernard. 1999. 'Deep throat' cellulitis. J. Infect. 38:134. (Letter.)
108. Del Mar, C. B., P. P. Glasziou, and A. B. Spinks. 2004. Antibiotics for sore throat. Cochrane Database Syst. Rev. 2:CD000023.
109. de Rautlin de la Roy, Y., V. Toma, B. Grignon, G. Grollier, and M-C. Paute. 1978. Abcès cérébral à Fusobacterium necrophorum. Importance des conditions de prélèvement et d'analyse bactériologique. Nouv. Presse Med. 7:3454-3455.
110. De Sena, S., D. L. Rosenfield, S. Santos, and I. Keller. 1996. Jugular thrombophlebitis complicating bacterial pharyngitis (Lemierre's syndrome). Pediatr. Radiol. 26:141-144.
111. de Veber, G., A. Chan, P. Monagle, V. Marzinotto, D. Armstrong, P. Massicotte, M. Leaker, and M. Andrew. 1998. Anticoagulation therapy in pediatric patients with sinovenous thrombosis. Arch. Neurol. 55:1533-1537.
112. de Veber, G., M. Andrew, C. Adams, B. Bjornson, F. Booth, D. J. Buckley, C. S. Camfield, M. David, P. Humphreys, P. Langevin, E. A. MacDonald, and J. Gillett. 2001. Cerebral sinovenous thrombosis in children. N. Engl. J. Med. 345:417-423.
113. de Veber, G., P. Monagle, A. Chan, D. MacGregor, R. Curtis, S. Lee, P. Vegh, M. Adams, V. Marzinotto, M. Leaker, P. Massicotte, D. Lillicrap, and M. Andrew. 1998. Prothrombotic disorders in infants and children with cerebral thromboembolism. Arch. Neurol. 55:1539-1543.
114. De Vos, A. I., R. N. van Rossem, E. P. M. van Elzakker, J. M. A. Nijhuis-Heddes, and E. Maartense. 2000. Lemierre's syndrome sepsis complicating an anaerobic oropharyngeal infection. Neth. J. Med. 59:181-183.
115. Dhawan, B., R. Chaudhry, A. Pandey, N. Nisar, and M. Singh. 1998. Anaerobic septicaemia by Fusobacterium necrophorum: Lemierre's syndrome. Indian J. Pediatr. 65:469-472.
116. Dixon, O. J., and F. C. Helwig. 1930. Thrombophlebitis of the internal jugular vein as a complication of tonsillitis. Ann. Otol. Rhinol. Laryn. 39:1137-1149.
117. Dodd, J. D., C. A. Souza, and N. L. Muller. 2006. High-resolution MDCT of pulmonary septic embolism: evaluation of the feeding vessel sign. Am. J. Roentgenol. 187:623-629.
118. Dorsey, S. T. 2002. A critically ill young man with septic emboli to the lungs. J. Emerg. Med. 22:415-417.
119. Doyle, K. J., and R. K. Jackler. 1991. Otogenic cavernous sinus thrombosis. Otolaryng. Head Neck. 104:873-877.
120. Drasar, B. S., and B. I. Duerden. 1991. Anaerobes in the normal flora of man, p. 162-179. In B. I. Duerden and B. S. Drasar (ed.), Anaerobes in human disease, Edward Arnold, London, United Kingdom.
121. Duboc, H. 1994. Lemierre and Sohier's mission (3-13 January 1942). Hist. Sci. Med. 28:33-39.
122. Ducroz, V., C. le Pajolec, E. Harbourn, and S. Bobin. 1993. Mastoïdites aiguës a germes anaérobies revue de la literature à propos d'un cas. Ann. Otolaryng. 110:55-59.
123. Dykhuizen, R. S., E. S. Olson, S. Clive, and J. G. Douglas. 1994. Necrobacillosis (Lemierre's syndrome): a rare cause of necrotizing pneumonia. Eur. Respir. J. 7:2246-2248.
124. Ellis, G. R., D. I. Gozzard, D. N. Looker, and G. J. Green. 1998. Postanginal septicaemia (Lemierre's disease) complicated by haemophagocytosis. J. Infect. 36:340-341.
125. Embree, J. E., T. Williams, and B. J. Law. 1988. Hepatic abscesses in a child caused by Fusobacterium necrophorum. Pediatr. Infect. Dis. J. 7:359-360.
126. Emery, D. L., J. A. Vaughan, B. L. Clark, J. H. Dufty, and D. J. Stewart. 1985. Cultural characteristics and virulence of strains of Fusobacterium necrophorum isolated from the feet of cattle and sheep. Aust. Vet. J. 62:43-46.
127. Engelke, C., E. J. Rummeny, and K. Marten. 2004. A patient with prolonged fever after pharyngotonsillitis. Br. J. Radiol. 77:627-628.
128. Enwonwu, C. O. 1995. Noma: a neglected scourge of children in sub-Saharan Africa. Bull. W. H. O. 73:541-545.
129. Enwonwu, C. O., W. A. Falker, Jr., and E. O. Idigbe. 2000. Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms. Crit. Rev. Oral Biol. Med. 11:159-171.
130. Epaulard, O., J.-P. Brion, J.-P. Stahl, B. Colombe, and M. Maurin. 2006. The changing pattern of fusobacterium infections in humans: recent experience with fusobacterium bacteraemia. Clin. Microbiol. Infect. 12:178-181.
131. Epstein, M., A. D. J. Pearson, S. J. Hudson, R. Bray, M. Taylor, and J. Beesley. 1992. Necrobacillosis with pancytopenia. Arch. Dis. Child. 67:958-959.
132. Escardó, J. A., A. Feyi-Waboso, C. M. Lane, and J. E. Morgan. 2000. Orbital cellulitis caused by Fusobacterium necrophorum. Am. J. Ophthal. 131:280-281.
133. Esposito, N. 2004. Final diagnosis - Fusobacterium necrophorum bacteraemia. http://path.upmc.edu/cases/case385/dx.html.
134. Estrera, A. S., M. J. Landay, J. M. Grisham, D. P. Sinn, and M. R. Platt. 1983. Descending necrotizing mediastinitis. Surg. Gynecol. Obstet. 157:545-552.
135. Eykyn, S. J. 1983. The therapeutic use of metronidazole in anaerobic infection: six years' experience in a London hospital. Surgery 93:209-214.
136. Eykyn, S. J. 1989. Necrobacillosis. Scand. J. Infect. Dis. 62:41-46.
137. Falkler, W. A., Jr., C. O. Enwonwu, and E. O. Idigbe. 1999. Isolation of Fusobacterium necrophorum from cancrum oris (noma). Am. J. Trop. Med. Hyg. 60:150-156.
138. Falkler, W. A., C. O. Enwonwu, A. J. Ewell, and E. O. Idigbe. 2000. Isolation of fusobacteria from the oral cavities of malnourished Nigerian children living in agricultural and herding villages. Oral Dis. 6:103-105.
139. Faussat, J. M., A. Coste, G. Roger, B. Page, H. Marrek, and P. Roulleau. 1993. Les thrombophlébites septiques de la veine jugulaire interne à porte d'entrée oro-pharyngée. Ann. Otolaryng. 110:445-449.
140. Fiesseler, F. W., P. B. Richman, and R. L. Riggs. 2001. Pharyngitis followed by hypoxia and sepsis: Lemierre syndrome. Am. J. Emerg. Med. 19:320-322. (Letter.)
141. Fiévez, L. 1963. Etude comparée des souches de Sphaerophorus nécrophorus isolées chez l'homme et l'animal. Presses Académiques Européennes, Brussels, Belgium.
142. Figueras, G., O. Garcia, O. Vall, X. Massaguer, and M. Salvadó. 1995. Otogenic Fusobacterium necrophorum meningitis in children. Pediatr. Infect. Dis. J. 14:627-628.
143. Finegold, S. M. 1977. Anaerobic bacteria in human disease, p. 13-14. Academic Press, New York, NY.
144. Finegold, S. M. 1991. Role of anaerobic bacteria in infections of the tonsils and adenoids. Ann. Otol. Rhinol. Laryng. 154(Suppl.):30-33.
145. Finegold, S. M. 1992. Anaerobic gram negative rods: Bacteroides and Fusobacterium, p. 1571-1580. In S. L. Gorbach, J. G. Bartlett, and N. R. Blacklow (ed.), Infectious diseases. W. B. Saunders, Philadelphia, PA.
146. Flügge, C. 1886. Zweiter Abschnitt. II. Bacillen. B. Für Thiere pathogene Bacillen Bacillus necrophorus (Löffler), p. 273. In Die mikroorganismen. Mit besonder berücksichtigung der aetiologie der infectionskrankheiten. FCW Vogel, Leipzig, Germany.
147. Forrester, L. J., B. J. Campbell, J. N. Berg, and J. T. Barrett. 1985. Aggregation of platelets by Fusobacterium necrophorum. J. Clin. Microbiol. 22:245-249.
148. Foulkes, G. D., C. E. Johnson, and H. P. Katner. 1990. Fusobacterium osteomyelitis associated with intraosseous gas. Clin. Orthop. Relat. Res. 251:246-248.
149. Fränkel, E. 1925. [Title unavailable.] Virch. Arch. 254:639.
150. Freeman, C. D., N. E. Klutman, and K. C. Lamp. 1997. Metronidazole a therapeutic review and update. Drugs 54:679-708.
151. Garcia, G. G., K. K. Amoako, D. L. Xu, T. Inoue, Y. Goto, and T. Shinjo. 1999. Chemical composition of endotoxins produced by Fusobacterium necrophorum subsp. necrophorum and F. necrophorum subsp. funduliforme. Microbios 100:175-179.
152. Garcia, M. M., K. M. Charlton, and K. A. McKay. 1975. Characterization of endotoxin from Fusobacterium necrophorum. Infect. Immun. 11:371-379.
153. Garcia Del Castillo, E., J. M. Morales, J. Crespo, M. Ruiz, J. Carballo, and C. Gomez. 1995. Thrombophlebitis of the cavernous sinus secondary to polysinusitis. Report of a new case. Acta Otorrhinolaringol. Esp. 46:60-62.
154. Garimella, S., A. Inaparthy, and T. Herchline. 2004. Meningitis due to Fusobacterium necrophorum in an adult. BMC Infect. Dis. http://www.biomedcentral.com/1471-2334/4/24.
155. Garnham, F., and P. Longstaff. 2005. "My back is killing me." Emerg. Med. J. 22:824-825.
156. Gerst, C., and J. M. Primrose. 1997. Septic arthritis of the ankle from Fusobacterium necrophorum. Acad. Emerg. Med. 4:1172-1173. (Letter.)
157. Ghaffar, F. A., M. Wördemann, and G. H. McCracken, Jr. 2001. Acute mastoiditis in children: a seventeen-year experience in Dallas, Texas. Pediatr. Infect. Dis. J. 20:376-380.
158. Go, C., J. M. Bernstein, A. L. de Jong, M. Sulek, and E. M. Friedman. 2000. Intracranial complications of acute mastoiditis. Int. J. Pediatr. Otorhinolaryngol. 52:143-148.
159. Gold, W. L., M. K. Kapral, M. R. Witme, W. A. Mahon, M. Ostrowski, and H. Villend. 1995. Postanginal septicaemia as a life-threatening complication of infectious mononucleosis. Clin. Infect. Dis. 20:1439-1440. (Letter.)
160. Goldenberg, N. A., R. Knapp-Clevenger, T. Hays, and M. J. Manco-Johnson. 2005. Lemierre's and Lemierre's-like syndromes in children: survival and thromboembolic outcomes. Pediatrics 116:543-548.
161. Goldhagen, J., B. A. Alford, L. H. Prewitt, L. Thompson, and M. K. Hostetter. 1988. Suppurative thrombophlebitis of the internal jugular vein: report of three cases and review of the pediatric literature. Pediatr. Infect. Dis. J. 7:410-414.
162. Golledge, C. L., M. H. Beaman, T. Weeramanthri, and T. V. Riley. 1990. Necrobacillosis-primary anaerobic septicaemia due to Fusobacterium necrophorum. Aust. N.Z. J. Med. 20:702-705.
163. Golpe, R., B. Marin, and M. Alonso. 1999. Lemierre's syndrome (necrobacillosis). Postgrad. Med. J. 75:141-144.
164. Gong, J., and J. Garcia. 1999. Lemierre's syndrome. Eur. Radiol. 9:672-674.
165. Gorbach, S. L., and J. G. Bartlett. 1974. Anaerobic infections (second of three parts). N. Engl. J. Med. 290:1237-1245.
166. Gowan, R. T., R. J. Mehran, P. Cardinal, and G. Jones. 2000. Thoracic complications of Lemierre syndrome. Can. Respir. J. 7:481-485.
167. Goyal, M., R. Sharma, Y. Jain, and M. Berry. 1995. Unusual radiological manifestations of Lemierre's syndrome: a case report. Ped. Radiol. 25:S105-S106.
168. Gudinchet, F., P. Maeder, P. Neveceral, and P. Schnyder. 1997. Lemierre's syndrome in children. Chest 112:271-273.
169. Guidet, B., G. Offenstadt, P. Pinta, D. Lesage, and A. Tembely. 1981. Une infection oubliée: le syndrome angine-infarctus pulmonaire à Fusobacterium necrophorum. Un cas avec insuffisance respiratoire aiguë. Méd. Maladies Infect. 11:462-464.
170. Guillemot, L., J. Hallé, and E. Rist. 1899. Recherches bactériologiques et expérimentales sur les pleurisies putrides. Arch. Méd. Exp. Anat. Pathol. 5:1904.
171. Gunn, A. A. 1956. Bacteroides septicaemia. J. R. Coll. Surg. 2:41.
172. Gupta, M., F. V. Castello, and H. H. Kesarwala. 1995. Respiratory failure caused by Lemierre's syndrome. Clin. Pediatr. 34:275-277.
173. Gurley, M. B., T. S. King, and F. Y. Tsai. 1996. Sigmoid sinus thrombosis associated with internal jugular venous occlusion: direct thrombolytic treatment. J. Endovasc. Surg. 3:306-314.
174. Haasper, C., F. W. Tecklenburg, J. B. Cochran, D. M. Habib, and C. D. Smith. 2004. A pain in the neck can lead to pain in the belly: Lemierre's syndrome. Int. Pediatr. 19:185-187.
175. Hadlock, F. P., R. J. Wallace, Jr., and M. Rivera. 1979. Pulmonary septic emboli secondary to parapharyngeal abscess: postanginal sepsis. Radiology 130:29-33.
176. Hagelskjaer, L., and G. Pedersen. 1993. Fusobacterium necrophorum septicemia complicated by liver abscess. APMIS 101:904-906.
177. Hagelskjaer, L. H., J. Prag, J. Malczynski, and J. H. Kristensen. 1998. Incidence and clinical epidemiology of necrobacillosis, including Lemierre's syndrome, in Denmark 1990-1995. Eur. J. Clin. Microbiol. Infect. Dis. 17:561-565.
178. Hagelskjaer Kristensen, L., and J. Prag. 2000. Human necrobacillosis, with emphasis on Lemierre's syndrome. Clin. Infect. Dis. 31:524-532.
179. Halasa, N. B., M. R. Griffin, Y. Zhu, and K. M. Edwards. 2002. Decreased number of antibiotic prescriptions in office based settings from 1993 to 1999 in children less than five years of age. Pediatr. Infect. Dis. J. 21:1023-1028.
180. Hall, C. 1939. Sepsis following pharyngeal infections. Ann. Otol. Rhinol. Laryngol. 48:905-925.
181. Hall, V., B. I. Duerden, J. T. Magee, H. C. Ryley, and J. S. Brazier. 1997. A comparative study of Fusobacterium necrophorum strains from human and animal sources by phenotypic reactions, pyrolysis mass spectrometry and SDS-PAGE. J. Med. Microbiol. 46:865-871.
182. Hallé, J. 1898. Recherches sur la bactériologie du canal génital de la femme. Faculté de Médicine de Paris, Paris, France.
183. Han, X. Y., J. S. Weinberg, S. S. Prabhu, S. J. Hassenbusch, G. N. Fuller, J. J. Tarrand, and D. P. Kontoyiannis. 2003. Fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis. J. Neurosurg. 99:693-700.
184. Handler, S. D., and W. S. Warren. 1979. Peritonsillar abscess: A complication of corticosteroid treatment in infectious mononucleosis. Int. J. Pediatr. Otorhi. 1:265-268.
185. Harar, R. P. S., A. MacDonald, D. Pullen, S. Ganesan, and A. J. Prior. 1996. Lemierre's syndrome: are we underdiagnosing this life-threatening infection? J. Otorhinolaryngol. Relat. Spec. 58:178-181.
186. Hardie, J. 1983. Microbial flora of the oral cavity, p. 162-196. In G. S. Shuster (ed.), Oral microbiology and infectious disease. Williams and Wilkins, Baltimore, MD.
187. Hardingham, M. 1987. Peritonsillar infections. Otolaryng. Clin. N. Am. 20:273-278.
188. Harrington, E., and M. A. Bleicher. 1980. Cryptogenic hepatic abscess in two uncompromised children. J. Pediatr. Surg. 15:660-662.
189. Hentges, D. J. 1993. The anaerobic microflora of the human body. Clin. Infect. Dis. 16(Suppl. 4):S175-S180.
190. Hirschel, B., A.-F. Allaz, and C.-A. Siegrist. 1983. Septicémie à anaérobes après infections oropharyngées (septicémie post-angine de Lemierre): un syndrome oublié. Schweiz Med. Wschr. 113:2008-2011.
191. 2) in the treatment of Lemierre syndrome. Undersea Hyperb. Med. 30:87-91.
192. Hoehn, K. S. 2005. Lemierre's syndrome: the controversy of anticoagulation. Pediatrics. 115:1415-1416.
193. Hoehn, S., and T. E. Dominguez. 2002. Lemierre's syndrome: an unusual cause of sepsis and abdominal pain. Crit. Care. Med. 30:1644-1647.
194. Hofstad, T., and I. Olsen. 2006. Fusobacterium and Leptotrichia, p. 1945-1956. In S. P. Boriello, P. R. Murray, G. Funke, (ed.), Topley & Wilson bacteriology, 10th ed., vol. 2. Oxford University Press, New York, NY.
195. Holland, B. W., W. F. McGuirt, Jr., and N. C. Winston-Salem. 2000. Imaging quiz case 2. Arch. Otol. Head Neck Surg. 126:1500-1504.
196. Hong, P., J. MacCormick, A. Lamothe, and M. Corsten. 2005. Lemierre syndrome: presentation of three cases. J. Otolaryngol. 34:352-358.
197. Hope, A., N. Bleach, and S. Ghiacy. 2002. Lemierre's syndrome as a consequence of acute supraglottis. J. Laryngol. Otol. 116:216-218.
198. Hughes, C. E., R. K. Spear, C. E. Shinabarger, and I. C. Tuna. 1994. Septic pulmonary emboli complicating mastoiditis: Lemierre's syndrome revisited. Clin. Infect. Dis. 18:633-635.
199. Hwang, J.-J., Y.-J. Lau, B.-S. Hu, Z.-Y. Shi, and Y.-H. Lin. 2002. Haemophilus parainfluenzae and Fusobacterium necrophorum liver abscess: a case report. J. Microbiol. Immunol. Infect. 35:65-67.
200. Ieven, M., K. Vael, M. De Mayer, A. De Schepper, and S. Pattyn. 1993. Three cases of Fusobacterium necrophorum septicaemia. Eur. J. Clin. Microbiol. 12:705-706.
201. Inoue, T., M. Kanoe, N. Goto, K. Matsumura, and K. Nakano. 1985. Chemical and biological properties of lipopolysaccharides from Fusobacterium necrophorum biovar A and biovar B strains. Nippon Juigaku Zasshi 47:639-645.
202. Irigoyen, M. M., M. Katz, and J. G. Larsen. 1983. Postanginal sepsis in adolescence. Pediatr. Infect. Dis. 2:248-250.
203. Islam, A. K. M. S., and J. M. Shneerson. 1980. Primary meningitis caused by Bacteroides fragilis and Fusobacterium necrophorum. Postgrad. Med. J. 56:351-353.
204. Jacobs, J. A., J. J. E. Hendriks, P. D. M. M. Verschure, A. M. van der Wurff, G. Freling, G. D. Vos, and E. E. Stobberingh. 1993. Meningitis due to Fusobacterium necrophorum subspecies necrophorum. Case report and review of the literature. Infection 21:57-60.
205. Jaffe, R. B., and E. B. Koschmann. 1970. Septic pulmonary emboli. Radiology 96:527-532.
206. Jaremko, J. L., A. Kirton, and J. L. Brenner. 2003. A 12-year-old girl with pharyngitis, meningitis and sinovenous thrombosis. Can. Med. Assoc. J. 169:811-812.
207. Jensen, A., L. H. Kristensen, and J. Prag. 2007. Fusobacterium necrophorum in young patients with tonsillitis and healthy controls examined by real-time PCR. Clin. Microbiol. Infect. 13:695-701.
208. Jensen, J. S., B Bruun, and B. Gahrn-Hansen. 1999. Unexpected cross-reaction with Fusobacterium necrophorum in a PCR for detection of mycoplasmas. J. Clin. Microbiol. 37:828-829.
209. Jokipii, A. M., P. Karma, K. Ojala, and L. Jokipii. 1977. Anaerobic bacteria in chronic otitis media. Arch. Otolaryngol. 103:278-280.
210. Jones, J. W., T. Riordan, and M. S. Morgan. 2001. Investigation of post-anginal sepsis and Lemierre's syndrome in the South West Peninsula. Commun. Dis. Public Health 4:278-282.
211. Jones, T. H., V. Bergvall, and J. P. P. Bradshaw. 1990. Carotid artery stenosis and thrombosis secondary to cavernous sinus thromboses in Fusobacterium necrophorum meningitis. Postgrad. Med. J. 66:747-750.
212. Jousimies-Somer, H., S. Savolainen, A. Mäkitie, and J. Ylikoski. 1993. Bacteriologic findings in peritonsillar abscesses in young adults. Clin. Infect. Dis. 16(Suppl. 4):S292-S298.
213. Jousimies-Somers, H. R., P. H. Summanen, H. Wexler, S. M. Finegold, S. E. Gharbia, and H. N. Shah. 2006. Bacteroides, Porphyromonas, Prevotella, Fusobacterium and other anaerobic gram negative bacilli, p. 880-901. In P. R. Murray, E. J. Baron, J. H. Jorgensen, M. A. Pfaller, and R. H. Yolken (ed.), Manual of clinical microbiology, 8th ed. ASM Press, Washington, DC.
214. Justin-Besançon, L. 1956. L'enseignement de la clinique au chevet du malade. L'exemple d'un grand clinician: Le Professeur André Lemierre. Sem. Hôp. Paris 74:387-392.
215. Kanoe, M. 1990. Fusobacterium necrophorum hemolysin in bovine hepatic abscess. Zentbl. Vet. B 37:770-773.
216. Kanoe, M., M. Yamanaka, and M. Inoue. 1989. Effects of Fusobacterium necrophorum on the mesenteric microcirculation of guinea pigs. Med. Microbiol. Immunol. 178:99-104.
217. Kanoe, M., Y. Koyanagi, C. Kondo, K. Mamba, T. Makita, and K. Kai. 1998. Location of haemagglutinin in bacterial cells of Fusobacterium necrophorum subsp. necrophorum. Microbios 96:33-38.
218. Kara, E., A. Sakarya, C. Keleçs, H. Borand, G. Pekindil, and C. Goktan. 2004. Case of Lemierre's syndrome presenting with thyroid abscess. Eur. J. Clin. Microbiol. Infect. Dis. 23:570-572.
219. Karanas, Y. L., K. K. Yim, B. A. Shuster, and W. C. Lineaweaver. 1995. Lemierre's syndrome: a case of postanginal septicaemia and bilateral flank abscesses. Ann. Plast. Surg. 35:525-528.
220. Karkos, P. D., A. Karkanevatos, S. Panagea, A. Dingle, and J. E. Davies. 2004. Lemierre's syndrome: how a sore throat can end in disaster. Eur. J. Emerg. Med. 11:228-230.
221. Katz, A., E. Leibovitz, D. Greenberg, S. Raiz, M. Greenwald-Maimon, A. Leiberman, and R. Dagan. 2003. Acute mastoiditis in southern Israel: a twelve year retrospective study (1990 through 2001). Pediatr. Infect. Dis. J. 22:878-882.
222. Kern, W., M. Dolderer, D. Krieger, M. Buchler, and P. Kern. 1992. Lemierre's syndrome with splenic abscesses. Dtsch. Med. Wochenschr. 117:1513-1517.
223. Kissling, K. K. 1929. Ueber postanginöse Sepsis. Munchener Med. Wochenschr. 28:1163-1168.
224. Kitch, T. T., and P. C. Appelbaum. 1989. Accuracy and reproducibility of the 4-hour ATB 32A method for anaerobe identification. J. Clin. Microbiol. 27:2509-2513.
225. Klinge, L., U. Vester, J. Schaper, and P. F. Hoyer. 2002. Severe Fusobacteria infections (Lemierre syndrome) in two boys. Eur. J. Pediatr. 161:616-618.
226. Knorr, M. 1923. Ueber die fusospirilläre symbiose, die Gattung Fusobacterium (K. B. Lehmann) und Spirillum sputigenum. II Mitteilung. Die Gattung Fusobacterium. Zentbl. Bakteriol. Parasitenkd. Infekt. Hyg. Abt. 1 Orig. 89:4-22.
227. Koay, C. B., T. Heyworth, and P. Burden. 1995. Lemierre syndrome - a forgotten complication of acute tonsillitis. J. Laryngol. Otol. 109:657-661.
228. Könönen, E., A. Kanervo, A. Takala, S. Asikainen, and H. Jousimies-Somer. 1999. Establishment of oral anaerobes during the first year of life. J. Dent. Res. 78:1634-1639.
229. Kowalsky, S. F., R. M. Echols, and E. M. McCormick. 1990. Comparative serum bactericidal activity of ceftizoxime/metronidazole, ceftizoxime, clindamycin, and imipenem against obligate anaerobic bacteria. J. Antimicrob. Chemo. 25:767-775.
230. Kuduvalli, P. M., C. M. Jukka, M. Stallwood, C. Battersby, T. Neal, G. Masterson, and G. Marx. 2005. Fusobacterium necrophorum-induced sepsis: an unusual case of Lemierre's syndrome. Acta Anaesth. Scand. 49:572-575.
231. Kuhlman, J. E., E. K. Fishman, and C. Teigen. 1990. Pulmonary septic emboli: diagnosis with CT. Radiology 174:211-213.
232. Langworth, B. F. 1977. Fusobacterium necrophorum: its characteristics and role as an animal pathogen. Bacteriol. Rev. 41:373-390.
233. Larsen, P. D., S. A. Chartrand, and E. D. Adickes. 1997. Fusobacterium necrophorum meningitis associated with cerebral vessel thrombosis. Pediatr. Infect. Dis. J. 16:330-331.
234. Lau, E. S., and R. Shuckett. 1993. Fusobacterium septic arthritis of the sternoclavicular joint. J. Rheumatol. 20:1979-1981.
235. Lechner, A., M. Bender, and H. Mittermayer. 2000. Lemierre's syndrome: two cases of septicemia due to Fusobacterium necrophorum. Anaerobe 6:139-141.
236. Lee, B. K., F. Lopez, M. Genovese, and J. S. Loutit. 1997. Lemierre's syndrome. South. Med. J. 90:640-643.
237. Lee, S. J., S. I. Cha, C. H. Kim, J. Y. Park, T. H. Jung, K. N. Jeon, and G. W. Kim. 2006. Septic pulmonary embolism in Korea: microbiology clinicoradiologic features, and treatment outcome. J. Infect. 54:230-234.
238. Lee, Y., L. H. Straffon, K. B. Welch, and W. J. Loesche. 2005. The transmission of anaerobic periodontopathic organisms. J. Dent. Res. 85:182-186.
239. Lemierre, A. 1936. On certain septicaemias due to anaerobic organisms. Lancet ii:701-703.
240. Lemierre, A. 1936. Sur un cas de septico-pyohémie à Bacillus funduliformis. Bull. Mém. Soc. Méd. Hôp. 19:366-385.
241. Lemierre, A., A. Guy, and M. Rudolf. 1929. Septicémies à Bacillus fragilis. Presse Méd. 37:1669.
242. Lemierre, A., A. Laporte, et Bloch-Michel. 1936. Phlegmon gazeux cervical á ≪Bacillus funduliformis≫. Bull. Mém. Soc. Méd. Hôp. 19:1558-1562.
243. Lemierre, A., R. Grégoire, A. Laporte, et R. Couvelaire. 1938. Les aspects chirurgicaux des infections à Bacilllus funduliformis. Acad. Méd. 119:352-359.
244. Le Moal, G., C. Landron, G. Grollier, B. Bataille, F. Roblot, P. Nassans, and B. Becq-Giraudon. 2003. Characteristics of brain abscess with isolation of anaerobic bacteria. Scand. J. Infect. Dis. 35:318-321.
245. Leugers, C. M., and R. Clover. 1995. Lemierre syndrome: postanginal sepsis. J. Am. Board Fam. Pract. 8:384-391.
246. Reference deleted.
247. Liu, A. C. Y., and J. D. Argent. 2002. Necrobacillosis - a resurgence? Clin. Radiol. 57:332-338.
248. Loeffler, F. 1884. Die Diphtherie beim Kalbe. Mitteilungen Kaiserlichen Gesundheitsamte 2:489-499.
249. Loesche, W. J. 1972. Dental infections. Proceedings of the international conference on anaerobic bacteria. Atlanta, GA.
250. Long, J. W. 1912. Excision of internal jugular vein for streptococcic thrombi vein and cavernous sinus causing paralysis of orbital muscles. Surg. Gynaecol. Obst.14:86.
251. Lorber, B. 2006. Bacteroides, Prevotella, Porphyromonas and Fusobacterium species (and other medically important anaerobic gram-negative bacilli), p. 2838-2846. In G. L. Mandell, J. E. Bennett, and R Dolin (ed.), Principles and practice of infectious diseases, 6th ed. Elsevier Churchill Livingstone, Philadelphia, PA.
252. Loupa, C., D. Voyatzoglou, H. Papadaki, G. Kouppari, and G. Saroglou. 2000. A 32-year-old woman with fever, sore throat, jaundice and pulmonary infiltrates. Clin. Microbiol. Infect. 6:325-326.
253. Lustig, L. R., B. C. Cusick, S. W. Cheung, and K. C. Lee. 1995. Lemierre's syndrome: two cases of postanginal sepsis. Otolaryngol. Head Neck Surg. 112:767-772.
254. Ma, M., E. C. Jauch, and M. Cousins Johnson. 2003. A case of Lemierre's syndrome. Eur. J. Emerg. Med. 10:139-142.
255. MacDonald, A. A., R. P. S. Harar, and A. J. Prior. 1995. Necrobacillosis: are we missing the early stages of this life-threatening infection? Lancet 346:1705. (Letter.)
256. MacDonald, K. L., M. T. Osterholm, C. W. Hedberg, C. G. Schrock, G. F. Peterson, J. M. Jentzen, S. A. Leonard, and P. M. Schlievert. 1987. Toxic shock syndrome. A newly recognized complication of influenza and influenzalike illness. JAMA 257:1053-1058.
257. Mancao, M., E. Manci, M. Figarola, and B. Estrada. 2005. Fusobacterium necrophorum mediastinal abscess presenting as an anterior chest wall mass in a child: a case report. Clin. Pediatr. 44:73-75.
258. Man̄é, S., M. Torres, J. Bugés, A. Rivas, C. Bruno, E. Rodriguez, J. A. Martinez, and A. Nubiola. 1992. Scintigraphic demonstration of jugular obstruction in a case of Lemierre syndrome. Clin. Nucl. Med. 17:233-235.
259. Maniglia, R. J., T. Roth, and E. A. Blumberg. 1997. Polymicrobial brain abscess in a patient infected with human immunodeficiency virus. Clin. Infect. Dis. 24:449-451.
260. Mann, K. A. 1994. Lemierre's syndrome following infectious mononucleosis. Clin. Microbiol. Newsl. 16:158-159.
261. Marangos, M. N., D. A. Fuchs-Ertman, H. P. Kourea, K. J. Meurer, P. A. Lerwick, S. H. Zimmerman, and A. J. Valenti. 2000. Cerebral infarct and adult respiratory distress syndrome in a patient with postanginal sepsis. Eur. Soc. Clin. Microbiol. Infect. Dis. 6:337-339.
262. Marklund, G., B. Carlsson, and C. Lundberg. 1984. Low secretory IgA concentrations in oral secretions during the acute phase of infectious mononucleosis. Scand. J. Infect. Dis. 16:241-246.
263. Marsh, P. D., and M. V. Martin. 1984. Oral microbiology, 2nd ed., p. 11-25. Van Norstrad Reinhold (UK) Co., Ltd., London, United Kingdom.
264. Martin, M. J., and E. D. Wright. 1995. A case of Fusobacterium necrophorum sepsis. J. Infect. 31:151-152.
265. Matten, E. C., and L. Grecu. 2006. Unilateral empyema as a complication of infectious mononucleosis: a pathogenic variant of Lemierre's syndrome. J. Clin. Microbiol. 44:659-661.
266. McLean, A. S., and K. Tyler. 1998. Cardiac tamponade in a postpartum woman with Lemierre's syndrome. Anaesth. Intens. Care 26:582-583.
267. Medical Research Council. 1938. Epidemics in schools. X. Tonsillectomy. Spect. Rept. Ser. 1938:118-125.
268. Mehta, N., and G. Aisenberg. 2006. Necrobacillosis without Lemierre's syndrome. Lancet 367:1702.
269. Meis, J. F. G. M., T. W. Polder, P. van de Kar, and J. A. A. Hoogkamp-Korstanje. 1993. Multiple brain abscesses and bacteremia in a child due to Fusobacterium necrophorum. Infection 21:174-176.
270. Migirov, L., S. Duvdevani, and J. Kronenberg. 2005. Otogenic intracranial complications: a review of 28 cases. Acta Otolaryngol. 125:819-822.
271. Mitchelmore, I. J., A. J. Prior, P. Q. Montgomery, and S. Tabaqchali. 1995. Microbiological features and pathogenesis of peritonsillar abscesses. Eur. J. Clin. Microbiol. Infect. Dis. 14:870-877.
272. Mitre, R. J., and E. B. Rotheram, Jr. 1974. Anaerobic septicaemia from thrombophlebitis of the internal jugular vein. JAMA 230:1168-1169.
273. Miyazato, S., T. Shinjo, H. Yago, and N. Nakamura. 1978. Fimbriae (pili) detected in Fusobacterium necrophorum. Nippon Juigaku Zasshi 40:619-621.
274. Møller, K., and B. Dreijer. 1997. Post-anginal sepsis (Lemierre's disease): a persistent challenge. Presentation of 4 cases. Scand. J. Infect. Dis. 29:191-194.
275. Moore, B. A., C. Dekle, and J. Werkhaven. 2002. Bilateral Lemierre's syndrome: a case report and literature review. Ear Nose Throat J. 81:234-252.
276. Moore, W. E. C., L. V. Holdeman, R. M. Smibert, I. J. Good, J. A. Burmeister, K. G. Palcanis, and R. R. Ranney. 1982. Bacteriology of experimental gingivitis in young adult humans. Infect. Immun. 38:651-667.
277. Moore-Gillon, J., T. H. Lee, S. J. Eykyn, and I. Phillips. 1984. Necrobacillosis: a forgotten disease. Br. Med. J. 288:1526-1527.
278. Moreno, S., J. G. Altozano, B. Pinilla, J. C. López. B. de Quirós, A. Ortega, and E. Bouza. 1989. Lemierre's disease: postanginal bacteremia and pulmonary involvement caused by Fusobacterium necrophorum. Rev. Infect. Dis. 11:319-324.
279. Morizono, S., M. Enjoji, N. Sonoda, M. Fukushima, M. Kuniyoshi, K. Kotoh, M. Nakamuta, and H. Nawata. 2005. Lemierre's syndrome: Porphyromonas asaccharolytica as a putative pathogen. Intern. Med. 44:350-353.
280. Mukau, L. 1985. Dissecting retropharyngeal abscess due to Fusobacterium necrophorum in an adult. South. Med. J. 78:476-478.
281. Nakamura, S., S. Sadoshima, Y. Doi, M. Yoshioka, S. Yamashita, H. Gotoh, and K. Onoyama. 2000. Internal jugular vein thrombosis, Lemierre's syndrome; oropharyngeal infection with antibiotic and anticoagulation therapy. J. Vasc. Dis. 51:173-177.
282. Narayanan, S., G. C. Stewart, M. M. Chengappa, L. Willard, W. Shuman, M. Wilkerson, and T. G. Nagaraja. 2002. Fusobacterium necrophorum leukotoxin induces activation and apoptosis of bovine leukocytes. Infect. Immun. 70:4609-4620.
283. Narayanan, S. K., M. M. Chengappa, G. C. Stewart, and T. G. Nagaraja. 2003. Immunogenicity and protective effects of truncated recombinant leukotoxin proteins of Fusobacterium necrophorum in mice. Vet. Microbiol. 93:335-347.
284. Narayanan, S. K., T. G. Nagaraja, M. M. Chengpappa, and G. C. Stewart. 2001. Cloning, sequencing, and expression of the leukotoxin gene from Fusobacterium necrophorum. Infect. Immun. 69:5447-5455.
285. Narongwanichgarn, W., N. Misawa, J. H. Jin, K. K. Amoako, E. Kawaguchi, T. Shinjo, T. Haga, and Y. Goto. 2003. Specific detection and differentiation of two subspecies of Fusobacterium necrophorum by PCR. Vet. Microbiol. 93:183-195.
286. Narsinghani, U., M. B. Schmidt, R. F. Jacobs, and K. S. Anand. 2001. Radiological case of the month. Arch. Pediatr. Adolesc. Med. 155:965-966.
287. Nastro, L. J., and S. M. Finegold. 1973. Endocarditis due to anaerobic gram-negative bacilli. Am. J. Med. 54:482-496.
288. Nguyen-Dinh, K. V., K. Marsot-Dupuch, F. Portier, and B. Lamblin. 2002. Lemierre syndrome: usefulness of CT in detection of extensive occult thrombophlebitis. J. Neuroradiol. 29:132-135.
289. Nicholson, L. A., C. J. Morrow, L. A. Corner, and A. L. Hodgson. 1994. Phylogenetic relationship of Fusobacterium necrophorum A, AB, and B biotypes based upon 16S rRNA gene sequence analysis. Int. J. Syst. Bacteriol. 44:315-319.
290. Nord, C. E. 1995. The role of anaerobic bacteria in recurrent episodes of sinusitis and tonsillitis. Clin. Infect. Dis. 20:1512-1524.
291. Nord, C. E., A. Heimdahl, and K. Tunér. 1988. Beta-lactamase producing anaerobic bacteria in the oropharynx and their clinical relevance. Scand. J. Infect. Dis. Suppl. 57:50-54.
292. Nuermberger, E. 4 August 2000. A previously healthy 23 year-old woman with sepsis. Case rounds case 17. http://hopkins-id.edu/education/ id_caserounds/caserounds17.html.
293. Oestreicher-Kedem, Y., E. Raveh, L. Kornreich, I. Yaniv, and H. Tamary. 2004. Prothrombotic factors in children with otitis media and sinus thrombosis. Laryngoscope 114:90-95.
294. Oh, T.-J., R. Eber, and H.-L. Wang. 2002. Periodontal diseases in the child and adolescent. J. Clin. Periodontol. 29:400-410.
295. Okada, Y., M. Kanoe, Y. Yaguchi, T. Watanabe, H. Ohmi, and K. Okamoto. 1999. Adherence of Fusobacterium necrophorum subspecies necrophorum to different animal cells. Microbios 99:95-104.
296. Olson, J. L., and N. Mandava. 2006. Bilateral intraocular involvement in Lemierre's syndrome. Br. J. Ophthalmol. 90:249-250 (Letter.)
297. Oteo, J., B. Aracil, C. Barros, J. I. Alós, and J. L. Gómez-Garcés. 1999. Bacteremic pharyngotonsillitis by Fusobacterium necrophorum: a prelude to Lemierre's syndrome. Clin. Microbiol. Newsl. 21:126-128.
298. Paaske, P. B., B. M. Rasmussen., and P. Illum. 1994. Fusobacterium pneumonia and death following uvulo-palato-pharyngoplasty. Head Neck 16:450-452.
299. Page, Y., C. Comtet, B. Tardy, F. Zeni, D. Thevent, F. Lucht, and J.-C. Bertrand. 1990. Disseminated intravascular coagulation in Fusobacterium necrophorum septicaemia. Scand. J. Infect. Dis. 22:743-747.
300. Palmer, A. L., J. D. Strain, D. B. Henry, F. M. Karrer, and E. A. F. Simoes. 1995. Postanginal sepsis after oropharyngeal trauma. Pediatr. Infect. Dis. J. 14:249-251.
301. Park, D., K. Rezajooi, and I. Sabin. 2006. Lemierre's syndrome an unusual manifestation of spinal infection. J. Bone Joint Surg. 88B:261-262.
302. Parulekar, S. S., D. F. Paonessa, A. Rapoport, and J. Kouyoumgian. 1978. Epstein-Barr virus, the ravager. Ann. Otol. 87:729-735.
303. Paster, B. J., S. K. Boches, J. L. Galvin, R. E. Ericson, C. N. Lau, V. A. Levanos, A. Sahasrabudhe, and F. E. Dewhirst. 2001. Bacterial diversity in human subgingival plaque. J. Bacteriol. 183:3770-3783.
304. Pham, H. C. 1935. Les septicémies dues au Bacillus funduliformis. Thèse pour le Doctorat en Médicine. Faculté de Médicine, Paris, France.
305. Pickering, M. C., T. Barkham. J. C. Mason, S. Shaunak, and K. A. Davies. 2000. Bilateral gluteal abscesses as a unique manifestation of Fusobacterium septicaemia. Rheumatology 39:224-225. (Letter.)
306. Pitkäranta, A., P. Lindahl, M. Raade, and R. Puohiniemi. 2004. Orbital abscess caused by Fusobacterium necrophorum. Int. J. Pediatr. Otorhi. 68:585-587.
307. Portman, M., D. Ingall, G. Westenfelder, and R. Yogev. 1984. Peritonsillar abscess complicating infectious mononucleosis. J. Pediatr. 104:742-744.
308. Potter, M. N., H. C. Drysdale, P. A. Price, and A. C. Buck. 1988. Disseminated intravascular coagulation with Fusobacterium necrophorum infection. Postgrad. Med. J. 64:155-156.
309. Prévot, A. R. 1938. Etudes de sytématique bactérienne III. Invalidité du genre Bacteroides Castellani et Chambers démembrement et reclassification. Ann. Inst. Pasteur Paris 60:285-307.
310. Pulcini, C., F. Vandenbos, S. Roth, V. Mondain-Miton, E. Bernard, P.-M. Roger, F. de Salvador-Guillouet, H. Hyvernat, F. Girard-Pipau, M. Mattéi, and P. Dellamonica. 2003. Syndrome de Lemierre: à propos de 6 cas. Rev. Méd. Intern. 24:17-23.
311. Quentin, C., M.-A. Desailly-Chanson, and C. Bebear. 1991. Evaluation of AN-Ident. J. Clin. Microbiol. 29:231-235.
312. Ramirez, S., T. G. Hild, C. N. Rudolph, J. R. Sty, S. C. Kehl, P. Havens, K. Henrickson, and M. J. Chusid. 2003. Increased diagnosis of Lemierre's syndrome and other Fusobacterium necrophorum infections at a children's hospital. Pediatrics 112:380-385.
313. Rathore, M. H., L. L. Barton, and L. M. Dunkle. 1990. The spectrum of fusobacterial infections in children. Pediatr. Infect. Dis. J. 9:505-508.
314. Razonable, R. R., A. E. Rahman, and W. R. Wilson. 2003. Lemierre syndrome variant: necrobacillosis associated with inferior vena cava thrombosis and pulmonary abscesses after trauma-induced leg abscess. Mayo Clin. Proc. 78:1153-1156.
315. Reilly, S., and A. T. Willis. 1980. β-Lactamase-producing anaerobes. Lancet ii:970-971. (Letter.)
316. Repanos, C., N. K. Chadha, and M. V. Griffiths. 2006. Sigmoid sinus thrombosis secondary to Lemierre's syndrome. Ear Nose Throat J. 85:98-101.
317. Reuben, M. S. 1933. Postanginal sepsis - report of nine cases. Arch. Pediatr. 52:152-185.
318. Reynolds, M. A., C. A. Hart, F. Harris, and L. S. Taitz. 1985. Anaerobes in acute otitis media. J. Infect. 10:262-264.
319. Riordan, T., and M. Wilson. 2004. Lemierre's syndrome: more than a historical curiosa. Postgrad. Med. J. 80:328-334.
320. Rist, E. 1898. Etudes bactériologiques sure les infections d'origine otique. Faculté de Médicine, Paris, France.
321. Roberts, D. S. 1967. The pathogenic synergy of Fusiformis necrophorus and Corynebacterium pyogenes. 1. Influence of the leucocidal exotoxin of F. necrophorus. Br. J. Exp. Pathol. 48:665-673.
322. Rosebury, T. 1966. Microrganisms indigenous to man. McGraw Hill, New York, NY.
323. Rubinstein, E., A. B. Onderdonk, and J. J. Rahal, Jr. 1974. Peritonsillar infection and bacteremia caused by Fusobacterium gonidiaformans. J. Pediatr. 85:673-675.
324. Rustia, M., and P. Shubik. 1972. Induction of lung tumors and malignant lymphomas in mice by metronidazole. J. Natl. Cancer Inst. 48:721-726.
325. Saginala, S., T. G. Nagaraja, Z. L. Tan, K. F. Lechtenberg, M. M. Chengappa, K. E. Kemp, and P. M. Hine. 1996. Serum neutralizing antibody response and protection against experimentally induced liver abscesses in steers vaccinated with Fusobacterium necrophorum. Am. J. Vet. Res. 57:483-488.
326. Sánchez, E. N., I. W. De Cal, N. A. Bernal, M. D. M. Rodrigo, J. U. Jaeger, F. C. Del Pozo, A. J. Blanco, A. C. Valenciano, and M. C. Echevarría. 2000. Fusobacterium osteomyelitis of the pubic symphysis in a healthy soccer player. J. Rheumatol. 27:2047-2048.
327. Sanders, R. V., M. B. Kirkpatrick, C. C. Dacso, and J. B. Bass, Jr. 1986. Suppurative thrombophlebitis of the internal jugular vein. Alabama J. Med. Sci. 23:92-95.
328. Sastre, J., E. Casas, J. Sierra, J. G. Puig, and A. Gil. 1991. Splenic abscess due to Fusobacterium necrophorum. Rev. Infect. Dis. 13:1249-1250. (Letter.)
329. Satchell, S. C., T. Riordan, and M. Beaman. 1998. An unusual case of an 'acute abdomen.' Postgrad. Med. J. 74:749-775.
330. Sayers, N. M., B. P. F. A. Gomes, D. B. Drucker, and A. S. Blinkhorn. 1997. Possible lethal enhancement of toxins from putative periodontopathogens by nicotine: implications for periodontal disease. J. Clin. Pathol. 50:245-249.
331. Schmid, T., H. Miskin, Y. Schlesinger, Z. Aragaman, and D. Kleid. 2005. Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome. Pediatrics 115:620-622.
332. Schmorl, G. 1891. Ueber ein pathogenes Fadenbacterium (Streptothrix cuniculi). Deutsch Z. Thiermed. 17:375-408.
333. Schottmüller, H. 1918. Ueber di Pathogenität anaërober Bazillen. Deutsche Med. Wochenschr. 44:1440. (Abstract.)
334. Schreckenberger, P. C., D. M. Celig, and W. M. Janda. 1988. Clinical evaluation of Vitek ANI Card for identification of anaerobic bacteria. J. Clin. Microbiol. 26:225-230.
335. Schwartz, B., S. M. Marcy, W. R. Phillips, M. A. Gerber, and S. F. Dowell. 1998. Pharyngitis - principles of judicious use of antimicrobial agents. Pediatrics 101:171-174.
336. Schwartz, H. C., and D. C. Nguyen. 1999. Postanginal septicaemia with external jugular venous thrombosis: case report. Br. J. Oral Max. Surg. 37:144-146.
337. Screaton, N. J., J. G. Ravenel, P. J. Lehner, E. R. Heitzman, and C. D. R. Flower. 1999. Lemierre syndrome: forgotten but not extinct - report of four cases. Radiology 213:369-374.
338. Seidenfeld, S. M., W. L. Sutker, and J. P. Luby. 1982. Fusobacterium necrophorum septicemia following oropharyngeal infection. JAMA 248:1348-1350.
339. Shadowen, R. D., and R. P. Trevor. 1989. Lemierre's postanginal septicaemia: internal jugular vein thrombosis related to pharyngeal infection. South. Med. J. 82:1583-1584.
340. Shannon, G. W., C. V. Ellis, and W. P. Stepp. 1983. Oropharyngeal Bacteroides melaninogenicus infection with septicemia: Lemierre's syndrome. J. Fam. Pract. 16:159-166.
341. Shapiro, J., M. P. Fried, and M. Strome. 1989. Postanginal sepsis. Head Neck 11:164-169.
342. Sharland, M., H. Kendall, D. Yeates, A. Randall, G. Hughes, P. Glasziou, and D. Mant. 2005. Antibiotic prescribing in general practice and hospital admissions for peritonsillar abscess, mastoiditis, and rheumatic fever in children: time trend analysis. Br. Med. J. 331:328-329.
343. Shaw, F. W., and I. A. Bigger. 1934. Necrobacillosis of the lung. JAMA 102:688-689.
344. Shek, M., A. Karamali, N. McGuire, P. Seifert, and N. Alperin. 1988. Bacterial sepsis with Fusobacterium sp. Arch. Int. Med. 148:2303.
345. Shinjo, T., and H. Kiyoyama. 1986. Pathogenicity of a non-hemagglutinating mutant strain of Fusobacterium necrophorum biovar A in mice. Nippon Juigaku Zasshi 48:523-527.
346. Shinjo, T., T. Fujisawa, and T. Mitsuoka. 1991. Proposal of two subspecies of Fusobacterium necrophorum (Flügge) Moore and Holdeman: Fusobacterium necrophorum subsp. necrophorum subsp. nov., nom. rev. (ex Flügge 1886), and Fusobacterium necrophorum subsp. funduliforme subsp. nov., nom. rev. (ex Hallé 1898). Int. J. Syst. Bacteriol. 41:395-397.
347. Sibai, K., and F. Sarasin. 2004. Syndrome de Lemierre: un diagnostic à ne pas oublier. Rev. Méd. Suisse Romande 124:693-695.
348. Sinave, C. P., G. J. Hardy, and P. W. Fardy. 1989. The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection. Medicine (Baltimore) 68:85-94.
349. Singhal, A., and M. D. Kertsein. 2001. Lemierre's syndrome. South. Med. J. 94:886-887.
350. Smith, G. E., S. Smith, H. Heatlie, J. N. R. Bashford, J. Hawker, D. Ashcroft, D. Millson, N. Q. Verlander, and R. Warren. 2004. What has happened to antimicrobial usage in primary care in the United Kingdom since the SMAC report? Description of trends in antimicrobial usage using the General Practice Research Database. J. Public Health 26:359-364.
351. Smith, G. R., and A. Turner. 1986. The adverse effect of dilution on the infectivity of Fusobacterium necrophorum culture. J. Hyg. (London) 96:199-203.
352. Smith, G. R., and E. A. Thornton. 1993. Pathogenicity of Fusobacterium necrophorum strains from man and animals. Epidemiol. Infect. 110:499-506.
353. Smith, G. R., and E. A. Thornton. 1997. Classification of human and animal strains of Fusobacterium necrophorum by their pathogenic effects in mice. J. Med. Microbiol. 46:879-882.
354. Smith, G. R., D. Till, L. M. Wallace, and D. E. Noakes. 1989. Enhancement of the infectivity of Fusobacterium necrophorum by other bacteria. Epidemiol. Infect. 102:447-458.
355. Smith, G. R., L. M. Wallace, and D. E. Noakes. 1990. Experimental observations on the pathogenesis of necrobacillosis. Epidemiol. Infect. 104:73-78.
356. Soave, R. L., and D. J. Kuchar. 2001. Bilateral forefoot gangrene secondary to Lemierre's disease. J. Am. Pod. Med. Assoc. 91:147-149. (Letter.)
357. Socransky, S. S., A. D. Haffajee, M. A. Cugini, C. Smith, and R. L. Kent, Jr. 1998. Microbial complexes in subgingival plaque. J. Clin. Periodontol. 25:134-144.
358. Socransky, S. S., and A. D. Haffajee. 1994. Evidence of bacterial etiology: a historical perspective. Periodontology 2000. 5:7-25.
359. Socransky, S. S., and S. D. Manganiello. 1971. The oral microbiota of man from birth to senility. J. Periodontol. 42:485-496.
360. Song, Y. 2005. PCR-based diagnostics for anaerobic infections. Anaerobe 11:79-91.
361. Sonsale, P. D., M. R. Philipson, and J. Bowskill. 2004. Septic arthritis of the knee due to Fusobacterium necrophorum. J. Clin. Microbiol. 42:3369-3370.
362. Spencer, C. H., C. W. Slusher, C. V. Sanders, and K. E. Aldridge. 1989. Fusobacterium necrophorum sepsis with cerebral infarction. South. Med. J. 82:1040-1043.
363. Spires, J. R., J. J. Owens, G. E. Woodson, and R. H. Miller. 1987. Treatment of peritonsillar abscess. Arch. Otolaryngol. Head Neck Surg. 113:984-986.
364. Stahlman, G. C., D. K. DeBoer, and N. E. Green. 1996. Fusobacterium osteomyelitis and pyarthrosis: a classic case of Lemierre's syndrome. J. Pediatr. Ortho. 16:529-532.
365. Stallworth, J. R., and J. M. Carroll. 1997. Lemierre's syndrome: new insights into an old disease. Clin. Pediatr. 36:715-718.
366. Stam, J., S. F. De Bruijn, and G. DeVeber. 2002. Anticoagulation for cerebral sinus thrombosis. Cochrane Database Syst. Rev. 4:CD002005.
367. Stavreas, N. P., C. D. Amanatidou, E. G. Hatzimanolis, I. Legakis, G. Naoum, E. Lakka-Papadodima, G. Georgoulias, P. Morfou, and S. Tsiodras. 2005. Thyroid abscess due to a mixed anaerobe infection with Fusobacterium mortiferum. J. Clin. Microbiol. 43:6202-6204.
368. Stenfors, L.-E., H.-M. Bye, S. Räisänen, and R. Myklebust. 2000. Bacterial penetration into tonsillar surface epithelium during infectious mononucleosis. J. Laryngol. Otol. 114:848-852.
369. Stenfors, L.-E., and S. Raisenen. 1996. Immunoglobulin-coated bacteria on the tonsillar surface during infectious mononucleosis. J. Laryngol. Otol. 110:339-342.
370. Stokroos, R. J., J. J. Manni, J. R. de Kruijk, and E. R. Soudijn. 1999. Lemierre syndrome and acute mastoiditis. Arch. Otolaryngol. Head Neck Surg. 125:589-591.
371. Stratton, C. W. 1996. Mechanisms of action for antimicrobial agents: general principles and mechanisms for selected classes of antibiotics, p. 591. In V. Lorian (ed.), Antibiotics in laboratory medicine, 4th ed. Williams and Wilkins, Baltimore, MD.
372. Stuart, G., and C. Wren. 1992. Endocarditis with acute mitral regurgitation caused by Fusobacterium necrophorum. Pediatr. Cardiol. 13:230-232.
373. Tan, Z. L., T. G. Nagaraja, and M. M. Chengappa. 1996. Fusobacterium necrophorum infections: virulence factors, pathogenic mechanism and control measures. Vet. Res. Commun. 20:113-140.
374. Tan, Z. L., T. G. Nagaraja, M. M. Chengappa, and J. S. Smith. 1994. Biological and biochemical characterisation of Fusobacterium necrophorum leukotoxin. Am. J. Vet. Res. 55:515-521.
375. Tanaka, I., K. Suzuki, E. Tanaka, and S. Baba. 1996. Investigation of normal bacterial flora in the upper respiratory tract. Acta Otolaryngol. Suppl. 525:44-50.
376. Tärnvik, A. 1986. Anaerobic meningitis in children. Eur. J. Clin. Microbiol. 5:271-274.
377. Teissier, P., J. Reilly, E. Rivalier, and F. Layani. 1929. Contribution à l'étude des septicémies primitives à microbes anaérobies. Etude clinique et expérimentale d'un cas de septicémie due au Bacillus funduliformis. Paris Méd. 7:297-306.
378. Teissier, P., J. Reilly, E. Rivalier, and V. Stéfanesco. 1931. Mémoires originaux. Les septicémies primitives dues au Bacillus funduliformisétude clinique, bactériologique et expérimentale. Ann. Méd. 30:97-144.
379. Thatcher, P. 2003. Hepatic abscesses caused by Fusobacterium necrophorum as part of the Lemierre syndrome. J. Clin. Gastroenterol. 37:196-197. (Letter.)
380. Trapp, C. M., J. Tamai, and M. R. Schleiss. 2005. Septic arthritis secondary to Fusobacterium necrophorum in a 4-year-old girl: case report and review of the literature. Pediatr. Infect. Dis. J. 24:846-847.
381. Tsuneishi, M., T. Yamamoto, S. Kokeguchi, N. Tamaki, K. Fukui, and T. Watanabe. 2006. Composition of the bacterial flora in tonsilloliths. Microbes Infect. 8:2384-2389.
382. Tunér, K., and C. E. Nord. 1983. Betalactamase-producing organisms in recurrent tonsillitis. Scand. J. Infect. Dis. Suppl. 39:83-85.
383. Uematsu, H., and E. Hoshino. 1992. Predominant obligate anaerobes in human periodontal pockets. J. Periodontal Res. 27:15-19.
384. Uffenforde, W. 1925. Die verwicklungen der akuten halsentzündung unter besonderer berücksichtigung der beteiligung des spatium parapharyngeum. Curt Kabitzch, Leipzig, Germany.
385. Van den Akker, E. H., A. W. Hoes, M. J. Burton, and A. G. M. Schilder. 2004. Large international differences in (adeno)tonsillectomy rates. Clin. Otolaryngol. 29:161-164.
386. Veillon, A., and A. Zuber. 1898. Sur quelques microbes strictement anaérobies et leur role en pathologie. Arch. Méd. Exp. 10:517-545.
387. Veldhoen, E. S., T. F. Wolfs, and A. J. van Vught. 2007. Two cases of fatal meningitis due to Fusobacterium necrophorum. Ped. Neurol. 36:261-263.
388. Velez, M. R., C. Dorsett, Jr., H. W. Ferguson, and K. Hansen. 2003. Lemierre's syndrome: a case report. J. Oral Maxillofac. Surg. 61:968-971.
389. Venkataraman, M. T., and M. Policar. 1997. Fever, sore throat and pulmonary infiltrates in a 20-year old-man. Chest 112:268-270.
390. Venkateswaran, S., and F. K. H. Sze. 2005. A case of Lemierre's syndrome presenting with multiple pulmonary abscesses associated with a tension hydropneumothorax resulting in a mediastinal shift. Ann. Acad. Med. Singapore 34:450-453.
391. Vogel, L. C., and K. M. Boyer. 1980. Metastatic complications of Fusobacterium necrophorum sepsis. Am. J. Dis. Child. 134:356-358.
392. Vohra, A., E. Saiz, and K. R. Ratzan. 1997. A young woman with a sore throat, septicaemia, and respiratory failure. Lancet 350:928.
393. Wade, W. 2002. Unculturable bacteria - the unchararacterized organisms that cause oral infections. J. R. Soc. Med. 95:81-83.
394. Wardle, J. K., M. J. Connolly, H. R. Ingham, P. Hudgson, and M. H. Snow. 1984. Necrobacillosis. Br. Med. J. 288:1916. (Letter.)
395. Wennberg, J. E., L. Blowers, R. Parker, and A. M. Gittelsohn. 1977. Changes in tonsillectomy rates associated with feedback and review. Pediatrics 59:821-826.
396. Westendorp, R. G., J. J. Hottenga, and P. E. Slagboom. 1999. Variation in plasminogen-activator-inhibitor-1 gene and risk of meningococcal septic shock. Lancet 354:561-563.
397. Wiedermann, C. J., and N. C. Kaneider. 2005. A meta-analysis of controlled trials of recombinant human activated protein C therapy in patients with sepsis. BMC Emerg. Med. http://www.biomedcenral.com/1471-227X/5/7.
398. Wolf, R. F. E., J. G. Konings, T. R. Prins, and J. Weits. 1991. Fusobacterium pyomyositis of the shoulder after tonsillitis. Acta Orthop. Scand. 62:595-596.
399. Woywodt, A., S. Merkel, W. Buth, H. Haller, and A. Schwarz. 2002. A swollen neck. Lancet 360:1838.
400. Yeung, P., and P. Noyce. 2001. Case report: Lemierre's syndrome following pharyngotonsillitis. Aust. J. Otolaryngol. http://www.findarticles. com/p/articles/mi_qa3868/is_200107/ai_n8961184.
401. Yousem, D. M., J. C. Scatarige, B. W. Gayler, and S. S. Siegelman. 1985. CT demonstration of postanginal sepsis. J. Otolaryngol. 14:333-335.
402. Yu, L., and J. B. Emans. 1988. Epidural abscess associated with spondylolysis. J. Bone Joint Surg. 70:444-447.
403. Zhang, F., T. G. Nagaraja, D. George, and G. C. Stewart. 2006. The two major subspecies of Fusobacterium necrophorum have distinct leukotoxin operon promoter regions. Vet. Microbiol. 112:73-78.