Serum neutralizing antibody response and protection against experimentally induced liver abscesses in steers vaccinated with Fusobacterium necrophorum

American Journal of Veterinary Research

Volumn 57, Issue 4, 1996, Pages 483-488

  Saginala, S ^a   Nagaraja, T G ^a   Tan, Z L ^a   Lechtenberg, K F ^b   Chengappa, M M ^a   Kemp, K E ^a   Hine, P M ^c  

^a KANSAS STATE UNIVERSITY   (United States)

^b Midwest Veterinary Supply Inc   (United States)

^c MALLINCKRODT PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL TOXIN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; EXOTOXIN; IMMUNOLOGICAL ADJUVANT; LEUKOTOXIN; TYLOSIN;

ABSCESS; ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ANTIBODY PRODUCTION; ARTICLE; BACTERIAL INFECTION; BLOOD; CATTLE; CATTLE DISEASE; DRUG EFFECT; FUSOBACTERIUM NECROPHORUM; IMMUNOLOGY; LIVER; LIVER DISEASE; LIVER FUNCTION TEST; MALE; ORCHIECTOMY; PATHOLOGY; SERODIAGNOSIS; VACCINATION;

ABSCESS; ADJUVANTS, IMMUNOLOGIC; ANIMAL FEED; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; BACTERIAL TOXINS; BACTERIAL VACCINES; CATTLE; CATTLE DISEASES; EXOTOXINS; FUSOBACTERIUM INFECTIONS; FUSOBACTERIUM NECROPHORUM; LIVER; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; NEUTRALIZATION TESTS; ORCHIECTOMY; TYLOSIN; VACCINATION;

EID: 0030124509     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Hale WH. Liver abscesses and founder in feedlot cattle. Anim Health Nutr 1985;40:12-20.
2. Langworth BF. Fusobacterium necrophorum: its characteristics and role as an animal pathogen. Bacteriol Rev 1977;41.373-390
3. Kanoe M, Izuchi Y, Kemi M, et al. Hepatic abscesses in fattened dairy steers. Jpn J Vet Sci 1979,41:73-76
4. Scanlan CM, Hathcock TL Bovine rumenitis-liver abscess complex, a bacteriological review. Cornell Vet 1983;73:288-297
5. Roberts DS The pathogenic synergy of Fusiformis necrophorus and Corynebacterium pyogenes. 1. Influence of the leukocidal exotoxin of F necrophorus Br J Exp Pathol 1967;48:665-673.
6. Roberts DS Toxic, allergenic and immunogenic factors of Fusiformis necrophorus. J Comp Pathol 1970;80:247-257.
7. Emery DL, Duffy JH, Clark BL. Biochemical and functional properties of a leukocidin produced by several strains of Fusobacterium necrophorum. Aust Vet J 1984;61:382-386.
8. Tan ZL, Nagaraja TG, Chengappa MM. Factors affecting the leukotoxin activity of Fusobacterium necrophorum. Vet Microbiol 1992,32:15-28
9. Hofsatd T, Kristoffersen T Preparation and chemical characteristics of endotoxic lipopolysaccharide from three strains of Sphaerophorus necrophorus Acta Pathol Microbiol Scand Sect B: 1971; 79:385-390.
10. Warner JF, Fales WH, Sutherland RC, et al. Endotoxin from Fusobacterium necrophorum of bovine hepatic abscess origin. Am J Vet Res 1975,36.1015-1019.
11. Garcia MM, Charlton KM, McKay KA. Characterization of endotoxin from Fusobacterium necrophorum. Infect Immun 1975;11: 371-379.
12. Berg JN, Scanlan CM. Studies of Fusobacterium necrophorium from bovine hepatic abscesses: biotypes, quantitation, virulence, and antibiotic susceptibility. Am J Vet Res 1982,43:1580-1586
13. Coyle-Dennis JE, Lauerman LH. Correlations between leukocidin production and virulence of two isolates of Fusobacterium necrophorum. Am J Vet Res 1979;40 274-276.
14. Tan ZL, Lechtenberg KF, Nagaraja TG, et at. Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. J Anim Sci 1994;72 502-508.
15. Garcia MM, Dorward WJ, Alexander DC, et al. Results of preliminary trials with Sphaerophorus necrophorus toxoids to control liver abscesses in feedlot cattle. Can J Comp Med 1974;38:222-226.
16. Clark BL, Emery DL, Stewart DJ, et al. Studies into immunization of cattle against interdigital necrobacillosis. Aust Vet J 1986;63:107-110.
17. Emery DL, Vaughan JA Generation of immunity against Fusobacterium necrophorum in mice inoculated with extracts containing leukotoxin Vet Microbiol 1986;12:255-268.
18. Smith GR, Wallace LM. Further observations on the weak immunogenicity of Fusobacterium necrophorum Res Vet Sci 1992;52: 262-263.
19. Potter EL, Wray MI, Muller RD, et al. Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle J Amm Sci 1985;61:1058-1065.
20. Hungate RE. A roll tube method for cultivation of strict anaerobes. In: Norris JR, Ribbons DW, eds. Methods in microbiology. Vol 3B New York: Academic Press Inc. 1969,117-132.
21. Lechtenberg KF, Nagaraja TG, Leipold HW, et al. Bacteriologic and histologic studies of hepatic abscesses in cattle. Am J Vet Res 1988,49:58-62.
22. Tan ZL, Nagaraja TG, Chengappa MM, et al. Biological and biochemical characterization of Fusobacterium necrophorum leukotoxin. Am J Vet Res 1994;55:515-521.
23. Tan ZL, Nagaraja TG, Chengappa MM, et al. Purification and quantification of Fusobacterium nercrophorum leukotoxin by using monoclonal antibodies. Vet Microbiol 1994,42.121-133
24. Vega MV, Maheswaran SK, Leininger JR, et al. Adaptation of a colorimetric microtitration assay for quantifying Pasteurella haemalytica A1 leukotoxin and antileukotoxin. Am J Vet Res 1987;48: 1559-1564.
25. Reddy PG, McVey DS, Chengappa MM, et al. Bovine recombinant granulocyte-macrophage colony-stimulating factor enhances bovine neutrophil functions in vitro. Am J Vet Res 1990;51: 1395-1399.
26. Lechtenberg KF, Nagaraja TG. Hepatic ultrasonography and blood changes in cattle with experimentally induced hepatic abscesses. Am J Vet Res 1991;52:803-809.
27. SAS/STAT guide for personal computers Cary, NC: SAS Institute Inc, 1987.
28. Jensen R, Flint JC, Griner LA Experimental hepatic necrobacillosis in beef cattle. Am J Vet Res 1954;15:5-14.
29. Garcia MM, McKay KA. Intraperitoneal immunization against necrobacillosis in experimental animals. Can J Comp Med 1978;42-121-127.
30. Brink DR, Lowry SR, Stock RA, et al. Severity of liver abscesses and efficiency of feed utilization of feedlot cattle J Anim Sci 1990;68:1201-1207
31. Styrt B, Walker RD, White JC, et al. Granulocyte plasma membrane damage by leukotoxic supernatant from Pasteurella haemolycica A1 and protection by immune serum. Can J Vet Res 1990; 54:146-150.
32. Emery DL, Edwards RD, Rothel JS. Studies on the purification of the leukocidin of Fusobacterium necrophorum and its neutralization by specific antisera. Vet Microbiol 1986;11:357-372.
33. Abe PM, Lennard ES, Holland JW. Fusobacterium necrophorum infection in mice as a model for the study of liver abscess formation and induction of immunity. Infect Immun 1976;13:1473-1478.
34. Conlon PJ, Hepper KP, Teresa GW. Evaluation of experimentally induced Fusobacterium necrophorum infections in mice Infect Immun 1977;15:510-517.
35. Smith GR, Turner A, Murray LG, et al. The weak immunogenicity of Fusobacterium necrophorum. J Hyg Camb 1985;95:59-68.
36. Smith GR, Wallace LM, Till D. Necrobacillosis and immunity in mice. Epidemiol Infect 1989;103:211-215.
37. Garcia MM, Alexander DC, McKay KA Biological characterization of Fusobacterium necrophorum cell fractions in preparation for toxin and immunization studies Infect Immun 1975;11 609-611
38. Wallace RJ, Brammall ML. The role of different species of bacteria in the hydrolysis of protein in the rumen. J Gen Microbiol 1985;131:821-832
39. Coyle-Dennis JE, Lauerman LH Biological and chemical characteristics of Fusobacterium necrophorum leukocidin. Am J Vet Res 1978;39:1790-1793.