Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1-R) antagonists

Current Topics in Medicinal Chemistry

Volumn 7, Issue 15, 2007, Pages 1433-1439

  DeVita, Robert J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Agonist; Antagonist; G protein coupled receptor; Melanin concentrating hormone obesity

Indexed keywords

2 AMINOQUINOLINE DERIVATIVE; 2 AZABICYCLO[2.2.2]QUINOLINE 6 CARBOXAMIDE; 2 PYRROLIDINYL QUINOLINE 6 CARBOXAMIDE; 4 AMINOQUINOLINE DERIVATIVE; AMIDE; AZETIDINE; HORMONE RECEPTOR BLOCKING AGENT; MELANIN CONCENTRATING HORMONE 1 RECEPTOR ANTAGONIST; PIPERIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

BINDING AFFINITY; BODY WEIGHT; CHEMICAL MODIFICATION; CONTINUOUS INFUSION; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FOOD INTAKE; IC 50; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OBESITY; PHYSICAL CHEMISTRY; REVIEW; RODENT; STRUCTURE ACTIVITY RELATION;

AMINATION; AMINOQUINOLINES; ANIMALS; DRUG DESIGN; HUMANS; RECEPTORS, PITUITARY HORMONE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35448950933     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802607782194789     Document Type: Review

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