Oxygenase domain of Drosophila melanogaster nitric oxide synthase: Unique kinetic parameters enable a more efficient NO release

Biochemistry

Volumn 46, Issue 42, 2007, Pages 11857-11864

  Ray, Sougata Sinha ^a,d   Tejero, Jesus ^c   Wang, Zhi Qiang ^c   Dutta, Tanmay ^a   Bhattacharjee, Arindam ^a   Regulski, Michael ^b   Tully, Tim ^b   Ghosh, Sanjay ^a   Stuehr, Dennis J ^c  

^a UNIVERSITY OF CALCUTTA   (India)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC PROPERTIES; CELL SIGNALING; DROSOPHILA MELANOGASTER NITRIC OXIDE SYNTHASE; FRUIT FLY DROSOPHILA MELANOGASTER;

BIOSYNTHESIS; CATALYST ACTIVITY; COMPUTER SIMULATION; HYDROXYLATION; KINETIC PARAMETERS; NITRIC OXIDE;

ENZYME KINETICS;

ARGININE; CITRULLINE; FERRIC HEME; FERRIC ION; FERROUS HEME; FERROUS ION; HEME; N(G) HYDROXYARGININE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; OXYGENASE; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; COMPUTER SIMULATION; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME METABOLISM; IMMUNITY; NONHUMAN; PARAMETER; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REACTION ANALYSIS; REACTION TIME; SIGNAL TRANSDUCTION;

ANIMALS; ARGININE; BIOPTERIN; BUFFERS; CATALYSIS; COMPUTER SIMULATION; DROSOPHILA MELANOGASTER; EDETIC ACID; ESCHERICHIA COLI; FERROUS COMPOUNDS; HEME; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, CHEMICAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATION-REDUCTION; OXYGENASES; PROTEIN STRUCTURE, TERTIARY; SPECTROPHOTOMETRY, ULTRAVIOLET; TEMPERATURE;

DROSOPHILA MELANOGASTER; MAMMALIA;

EID: 35448943235     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700803p     Document Type: Article

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