Stromal cell-derived factor-1 promotes cell migration and tumor growth of colorectal metastasis

Neoplasia

Volumn 9, Issue 10, 2007, Pages 862-870

  Kollmar, Otto ^a   Rupertus, Kathrin ^a   Scheuery, Claudia ^a   Junker, Bastian ^a   Tilton, Bettina ^a   Schilling, Martin K ^a   Mengery, Michael D ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Angiogenesis; Cancer; Chemokine; Metastasis; SDF 1

Indexed keywords

CASPASE 3; CELL NUCLEUS ANTIGEN; CHEMOKINE RECEPTOR CXCR4; GREEN FLUORESCENT PROTEIN; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INVASION; CARCINOGENESIS; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TUMOR VASCULARIZATION;

EID: 35448930176     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.07559     Document Type: Article

References (51)

1. Abdalla EK, Vauthey JN, Ellis LM, Ellis V, Pollock R, Broglio KR, Hess K, and Curley SA (2004). Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases. Ann Surg 239, 818-825.
2. Choti MA, Sitzmann JV, Tiburi MF, Sumetchotimetha W, Rangsin R, Schulick RD, Lillemoe KD, Yeo CJ, and Cameron JL (2002). Trends in long-term survival following liver resection for hepatic colorectal metastases. Ann Surg 235, 759-766.
3. Yamamoto J, Shimada K, Kosuge T, Yamasaki S, Sakamoto M, and Fukuda H (1999). Factors influencing survival of patients undergoing hepatectomy for colorectal metastases. Br J Surg 86, 332-337.
4. Fong Y (1999). Surgical therapy of hepatic colorectal metastasis. CA Cancer J Clin 49, 231-255.
5. Elias D, Liberale G, Vernerey D, Pocard M, Ducreux M, Boige V, Malka D, Pignon JP, and Lasser P (2005). Hepatic and extrahepatic colorectal metastases: when resectable, their localization does not matter, but their total number has a prognostic effect. Ann Surg Oncol 12, 900-909.
6. Labow DM, Buell JE, Yoshida A, Rosen S, and Posner MC (2002). Isolated pulmonary recurrence after resection of colorectal hepatic metastases - is resection indicated? Cancer J 8, 342-347.
7. Yoshidome H, Ito H, Kimura F, Ambiru S, Shimizu H, Togawa A, Ohtsuka M, Kato A, Nukui Y, and Miyazaki M (2004). Surgical treatment for extrahepatic recurrence after hepatectomy for colorectal metastases. Hepatogastroenterology 51, 1805-1809.
8. Folkman J (1992). The role of angiogenesis in tumor growth. Semin Cancer Biol 3, 65-71.
9. Chambers AF, Groom AC, and MacDonald IC (2002). Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2, 563-572.
10. Baggiolini M (1998). Chemokines and leukocyte traffic. Nature 392, 565-568.
11. Burger JA and Kipps TJ (2006). CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 107, 1761-1767.
12. Müller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN, et al. (2001). Involvement of chemokine receptors in breast cancer metastasis. Nature 410, 50-56.
13. Guleng B, Tateishi K, Ohta M, Kanai F, Jazag A, Ijichi H, Tanaka Y, Washida M, Morikane K, Fukushima Y, et al. (2005). Blockade of the stromal cell-derived factor-1/CXCR4 axis attenuates in vivo tumor growth by inhibiting angiogenesis in a vascular endothelial growth factor-independent manner. Cancer Res 65, 5864-5871.
14. Zeelenberg IS, Ruuls-Van Stalle L, and Roos E (2003). The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. Cancer Res 63, 3833-3839.
15. Ottaiano A, Franco R, Aiello Talamanca A, Liguori G, Tatangelo F, Delrio P, Nasti G, Barletta E, Facchini G, Daniele B, et al. (2006). Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients. Clin Cancer Res 12, 2795-2803.
16. Kim J, Mori T, Chen SL, Amersi FF, Martinez SR, Kuo C, Turner RR, Ye X, Bilchik AJ, Morton DL, et al. (2006). Chemokine receptor CXCR4 expression in patients with melanoma and colorectal cancer liver metastases and the association with disease outcome. Ann Surg 244, 113-120.
17. Kollmar O, Schilling MK, and Menger MD (2004). Experimental liver metastasis: standards for local cell implantation to study isolated tumor growth in mice. Clin Exp Metastasis 21, 453-460.
18. Menger MD and Lehr HA (1993). Scope and perspectives of intravital microscopy - bridge over from in vitro to in vivo. Immunol Today 14, 519-522.
19. Lehr HA, Leunig M, Menger MD, Nolte D, and Messmer K (1993). Dorsal skinfold chamber technique for intravital microscopy in nude mice. Am J Pathol 143, 1055-1062.
20. Menger MD, Laschke MW, and Vollmar B (2002). Viewing the microcirculation through the window: some twenty years experience with the hamster dorsal skinfold chamber. Eur Surg Res 34, 83-91.
21. Vajkoczy P, Farhadi M, Gaumann A, Heidenreich R, Erber R, Wunder A, Tonn JC, Menger MD, and Breier G (2002). Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2. J Clin Invest 109, 777-785.
22. Rupertus K, Kollmar O, Scheuer C, Junker B, Menger MD, and Schilling MK (2007). Major but not minor hepatectomy accelerates engraftment of extrahepatic tumor cells. Clin Exp Metastasis 24, 39-48.
23. Erber R, Thurnher A, Katsen AD, Groth G, Kerger H, Hammes HP, Menger MD, Ullrich A, and Vajkoczy P (2004). Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. FASEB J 18, 338-340.
24. Kollmar O, Junker B, Rupertus K, Menger MD, and Schilling MK (2007). Studies on MIP-2 and CXCR2 expression in a mouse model of extrahepatic colorectal metastasis. Eur J Surg Oncol 33, 803-811.
25. Kollmar O, Junker B, Rupertus K, Scheuer C, Menger MD, and Schilling MK (2007). Liver resection-associated macrophage inflammatory protein-2 stimulates engraftment but not growth of colorectal metastasis at extrahepatic sites. J Surg Res (Epub 2007 June 8).
26. Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, Penfold ME, Sunshine MJ, Littman DR, Kuo CJ, et al. (2006). A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med 203, 2201-2213.
27. Tilton B, Ho L, Oberlin E, Loetscher P, Baleux F, Clark-Lewis I, and Thelen M (2000). Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes. J Exp Med 192, 313-324.
28. Darash-Yahana M, Pikarsky E, Abramovitch R, Zeira E, Pal B, Karplus R, Beider K, Avniel S, Kasem S, Galun E, et al. (2004). Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J 18, 1240-1242.
29. Engl T, Relja B, Marian D, Blumenberg C, Muller I, Beecken WD, Jones J, Ringel EM, Bereiter-Hahn J, Jonas D, et al. (2006). CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins. Neoplasia 8, 290-301.
30. Strieter RM, Belperio JA, Phillips RJ, and Keane MP (2004). CXC chemokines in angiogenesis of cancer. Semin Cancer Biol 14, 195-200.
31. Balkwill F (2003). Chemokine biology in cancer. Semin Immunol 15, 49-55.
32. Loberg RD, Day LL, Harwood J, Ying C, St John LN, Giles R, Neeley CK, and Pienta KJ (2006). CCL2 is a potent regulator of prostate cancer cell migration and proliferation. Neoplasia 8, 578-586.
33. Phillips RJ, Burdick MD, Lutz M, Belperio JA, Keane MP, and Strieter RM (2003). The stromal derived factor-1/CXCL12 -CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. Am J Respir Crit Care Med 167, 1676-1686.
34. Ohira S, Sasaki M, Harada K, Sato Y, Zen Y, Isse K, Kozaka K, Ishikawa A, Oda K, Nimura Y, et al. (2006). Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factor-alpha and stromal-derived factor-1 released in stroma. Am J Pathol 168, 1155-1168.
35. Brand S, Dambacher J, Beigel F, Olszak T, Diebold J, Otte JM, Goke B, and Eichhorst ST (2005). CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. Exp Cell Res 310, 117-130.
36. Ottaiano A, di Palma A, Napolitano M, Pisano C, Pignata S, Tatangelo F, Botti G, Acquaviva AM, Castello G, Ascierto PA, et al. (2005). Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells. Cancer Immunol Immunother 54, 781-791.
37. Pan J, Mestas J, Burdick MD, Phillips RJ, Thomas GV, Reckamp K, Belperio JA, and Strieter RM (2006). Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol Cancer 5, 56.
38. Zhang L, Yeger H, Das B, Irwin MS, and Baruchel S (2007). Tissue microenvironment modulates CXCR4 expression and tumor metastasis in neuroblastoma. Neoplasia 9, 36-46.
39. Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, and Weinberg RA (2005). Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348.
40. Barbero S, Bonavia R, Bajetto A, Porcile C, Pirani P, Ravetti JL, Zona GL, Spaziante R, Florio T, and Schettini G (2003). Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. Cancer Res 63, 1969-1974.
41. Lee BC, Lee TH, Avraham S, and Avraham HK (2004). Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells. Mol Cancer Res 2, 327-338.
42. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, and Greenberg ME (1997). Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91, 231-241.
43. Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S, and Reed JC (1998). Regulation of cell death protease caspase-9 by phosphorylation. Science 282, 1318-1321.
44. Kops GJ, de Ruiter ND, De Vries-Smits AM, Powell DR, Bos JL, and Burgering BM (1999). Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 398, 630-634.
45. Strieter RM, Polverini PJ, Kunkel SL, Arenberg DA, Burdick MD, Kasper J, Dzuiba J, Van Damme J, Walz A, Marriott D, et al. (1995). The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem 270, 27348-27357.
46. Bachelder RE, Wendt MA, and Mercurio AM (2002). Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res 62, 7203-7206.
47. Salcedo R and Oppenheim JJ (2003). Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses. Microcirculation 10, 359-370.
48. Tachibana K, Hirota S, Iizasa H, Yoshida H, Kawabata K, Kataoka Y, Kitamura Y, Matsushima K, Yoshida N, Nishikawa S, et al. (1998). The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393, 591-594.
49. Yang SX, Chen JH, Jiang XF, Wang QL, Chen ZQ, Zhao W, Feng YH, Xin R, Shi JQ, and Bian XW (2005). Activation of chemokine receptor CXCR4 in malignant glioma cells promotes the production of vascular endothelial growth factor. Biochem Biophys Res Commun 335, 523-528.
50. Kryczek I, Lange A, Mottram P, Alvarez X, Cheng P, Hogan M, Moons L, Wei S, Zou L, Machelon V, et al. (2005). CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. Cancer Res 65, 465-472.
51. Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, et al. (2006). Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism. Cardiovasc Res 69, 925-935.