Reproductive toxicity assessment of lasofoxifene, a selective estrogen receptor modulator (SERM), in male rats

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 71, Issue 3, 2004, Pages 142-149

  Cappon, Gregg D ^a,b   Horimoto, Masao ^b   Hurtt, Mark E ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b PFIZER INC   (United States)

Author keywords

Fertility; Lasofoxifene; Reproduction; Spermatogenesis

Indexed keywords

LASOFOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COITUS; CONTROLLED STUDY; EPIDIDYMIS; FEMALE; MALE; MALE FERTILITY; MALE GENITAL SYSTEM; NONHUMAN; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; PROSTATE; RAT; REPRODUCTIVE TOXICITY; SEMINAL VESICLE; SPERMATOGENESIS; SPERMATOZOON MOTILITY; TESTIS; ANESTRUS; CHILDBIRTH; DRUG EFFECT; DRUG RECEPTOR BINDING; ESTRUS CYCLE; FEMALE FERTILITY; FEMALE GENITAL SYSTEM; NIDATION; PREGNANCY;

ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; EPIDIDYMIS; ESTROGENS; FEMALE; FERTILITY; MALE; ORGAN SIZE; OSTEOPOROSIS; PATERNAL EXPOSURE; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SEMINAL VESICLES; SPERM MOTILITY; TETRAHYDRONAPHTHALENES; TIME FACTORS; EMBRYO IMPLANTATION; ESTROUS CYCLE; MATERNAL EXPOSURE; PARTURITION; PREGNANCY; PREGNANCY, ANIMAL;

ANIMALIA;

EID: 3543133714     PISSN: 15429733     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdrb.20008     Document Type: Article

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