Increased adrenocorticotropin suppression following dexamethasone administration in sexually abused adolescents with posttraumatic stress disorder

Psychoneuroendocrinology

Volumn 29, Issue 10, 2004, Pages 1281-1289

  Duval, Fabrice ^a,b,c   Crocq, Marc Antoine ^a,b   Guillon, Marie Sabine ^b   Mokrani, Marie Claude ^b   Monreal, José ^a   Bailey, Paul ^a   Macher, Jean Paul ^a,b  

^a Centre Hospitalier de Rouffach   (France)

^b Inst Res Neurosci and Psychiat   (France)

^c CENTRE HOSPITALIER   (France)

Author keywords

ACTH; Adolescents; Cortisol; Dexamethasone; HPA; PTSD

Indexed keywords

CORTICOTROPIN; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE;

ADOLESCENT; ADULT; BECK DEPRESSION INVENTORY; BLOOD SAMPLING; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; CORTICOTROPIN BLOOD LEVEL; DEXAMETHASONE SUPPRESSION TEST; FEMALE; HORMONE BLOOD LEVEL; HORMONE DETERMINATION; HOSPITAL ADMISSION; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; HYDROCORTISONE BLOOD LEVEL; MALE; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; QUESTIONNAIRE; RATING SCALE; RECEPTOR SENSITIVITY; SEXUAL ABUSE; STATISTICAL SIGNIFICANCE; STRESS;

ADAPTATION, PSYCHOLOGICAL; ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ADULT; AGE FACTORS; CHILD ABUSE, SEXUAL; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; PITUITARY-ADRENAL SYSTEM; RECEPTORS, GLUCOCORTICOID; SEX FACTORS; STIMULATION, CHEMICAL; STRESS DISORDERS, POST-TRAUMATIC;

EID: 3543120157     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2004.03.006     Document Type: Conference Paper

References (61)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. fourth ed:1994;American Psychiatric Press, Washington. pp. 424-429
2. Baker D.G., West S.A., Nicholson W.E., Ekhator N.N., Kasckow J.W., Hill K.K., Bruce A.B., Orth D.N., Geracioti T.D. Jr. Serial CSF corticotropin- releasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder. Am. J. Psychiatry. 156:1999;585-588
3. Bailly D. Aspects neuro-endocriniens de la dépression de l'enfant et de l'adolescent. Bailly D. Les aspects neuro-endocriniens des troubles de l'humeur. 1995;232-259 Doin, Velizy
4. Beck A.T., Ward C.H., Mendelson M., Mock J., Erbaugh J. An inventory for measuring depression. Arch. Gen. Psychiatry. 4:1961;561-567
5. Birmaher B., Dahl R.E., Ryan N.D., Rabinovich H., Ambrosini P., al-Shabbout M., Novacenko H., Nelson B., Puig-Antich J. The dexamethasone suppression test in adolescent outpatients with major depressive disorder. Am. J. Psychiatry. 149:1992;1040-1045
6. Bremner J.D., Southwick S.M., Johnson D.R., Yehuda R., Charney D.S. Childhood physical abuse and combat-related posttraumatic stress disorder in Vietnam veterans. Am. J. Psychiatry. 150:1993;235-239
7. Bremner J.D., Licinio J., Darnell A., Krystal J.H., Owens M.J., Southwick S.M., Nemeroff C.B., Charney D.S. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. Am. J. Psychiatry. 154:1997;624-629
8. Bremner J.D., Vythilingam M., Vermetten E., Adil J., Khan S., Nazeer A., Afzal N., McGlashan T., Elzinga B., Anderson G.M., Heninger G., Southwick S.M., Charney D.S. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology. 28:2003;733-750
9. Cardena E. Psychometric review of the Stanford Acute Stress Reaction Questionnaire (SASRQ). Stamm B.H. Measurement of Stress, Trauma, and Adaptation. 1996;Sidran Press, Lutherville
10. Carrion V.G., Weems C.F., Ray R.D., Glaser B., Hessl D., Reiss A.L. Diurnal salivary cortisol in pediatric posttraumatic stress disorder. Biol. Psychiatry. 5:2002;575-582
11. Carroll B.J., Feinberg M., Greden J.F., Tarika J., Albala A.A., Hasket R.F., James N.M., Kronfol Z., Lohr N., Steiner M., De Vigne J.P., Young E. A specific laboratory test for the diagnosis of melancholia: standardisation, validation, and clinical utility. Arch. Gen. Psychiatry. 38:1981;15-22
12. Cole M.A., Kim P.J., Kalman B.A., Spencer R.L. Dexamethasone suppression of corticosteroid secretion: evaluation of the site of action by receptor measures and functional studies. Psychoneuroendocrinology. 25:2000;151-167
13. Corrigal R., Mitchell B. Service innovations: rethinking in-patient provision for adolescents. A report from a new service. Psychiatric Bull. 26:2002;288-392
14. Coupland, N.J., Hegadoren, K.M., Myholm, J., Sihra, S., Chan, J., Mitchell, E., 2001. Beclomethasone-induced vasoconstriction in posttraumatic stress disorder. Canadian College of Neuropsychopharmacology Annual Meeting; June 17-20; Banff (AB). p. 35.
15. De Bellis M.D., Chrousos G.P., Dorn L.D., Burke L., Helmers K., Kling M.A., Trickett P.K., Putnam F.W. Hypothalamic-pituitary-adrenal axis dysregulation in sexually abused girls. J. Clin. Endocrinol. Metab. 78:1994;249-255
16. De Bellis M.D., Baum A.S., Birmaher B., Keshavan M.S., Eccard C.H., Boring A.M., Jenkins F.J., Ryan N.D. A.E. Bennett Research Award. Developmental traumatology. Part I: Biological stress systems. Biol. Psychiatry. 45:1999;1259-1270
17. Delahanty D.L., Raimonde A.J., Spoonster E. Initial posttraumatic urinary cortisol levels predict subsequent PTSD symptoms in motor vehicle accident victims. Biol. Psychiatry. 48:2000;940-947
18. Dinan T.G., Barry S., Yatham L.N., Mobayed M., Brown I. A pilot study of a neuroendocrine test battery in posttraumatic stress disorder. Biol. Psychiatry. 28:1990;665-672
19. Elzinga B.M., Schmahl C.G., Vermetten E., van Dyck R., Bremner J.D. Higher cortisol levels following exposure to traumatic reminders in abuse-related PTSD. Neuropsychopharmacology. 28:2003;1656-1665
20. Endler N.S., Parker J.D., Butcher J.N. A factor analytic study of coping styles and the MMPI-2 content scales. J. Clin. Psychol. 49:1993;523-527
21. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinician Edition. 1997;American Psychiatric Press, Washington
22. Freud, S., 1955. In: Strachey, J. (Ed.), Beyond the Pleasure Principle, Standard Edition, vol. XVIII. The Hogarth Press, London, p. 31.
23. Goenjian A.K., Yehuda R., Pynoos R.S., Steinberg A.M., Tashjian M., Yang R.K., Najarian L.M., Fairbanks L.A. Basal cortisol, dexamethasone suppression of cortisol, and MHPG in adolescents after the 1988 earthquake in Armenia. Am. J. Psychiatry. 153:1996;929-934
24. Halbreich U., Olympia J., Carson S., Glogowski J., Yeh C.M., Axelrod S., Desu M.M. Hypothalamo-pituitary-adrenal activity in endogenously depressed post-traumatic stress disorder patients. Psychoneuroendocrinology. 14:1989;365-370
25. Hamilton M. The assessment of anxiety states by rating. Br. J. Med. Psychol. 32:1959;50-55
26. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry. 23:1960;56-62
27. Hanssenne M., Charles G., Pholine P., Panzer M., Pitchot W., Gonzalez-Moreno A., Ansseau M. Mesure subjective de l'impact d'un événement:traduction française et validation de l'échelle de Horowitz. Psychol. Méd. 25:1993;86-88
28. Heim C., Owens M.J., Plotsky P.M., Nemeroff C.B. Persistent changes in corticotropin-releasing factor systems due to early life stress: relationship to the pathophysiology of major depression and post-traumatic stress disorder. Psychopharmacol. Bull. 33:1997;185-192
29. Heim C., Newport J., Heit S., Graham Y.P., Wilcox M., Bonsall R., Miller A.H., Nemeroff C.B. Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. JAMA. 284:2000;592-597
30. Horowitz M.J., Wilner N., Alvarez W. Impact of event scale: a measure of subjective distress. Psychosom. Med. 41:1979;209-218
31. Kaufman J., Birmaher B., Perel J., Dahl R.E., Moreci P., Nelson B., Wells W., Ryan N.D. The corticotropin-releasing hormone challenge in depressed abused, depressed nonabused, and normal control children. Biol. Psychiatry. 42:1997;669-679
32. Kellner M., Yehuda R. Do panic disorder and posttraumatic stress disorder share a common psychoneuroendocrinology? Psychoneuroendocrinology. 24:1999;485-504
33. King J.A., Mandansky D., King S., Fletcher K.E., Brewer J. Early sexual abuse and low cortisol. Psychiatry Clin. Neurosci. 55:2001;71-74
34. Kosten T.R., Wahby V., Giller E. Jr., Mason J. The dexamethasone suppression test and thyrotropin-releasing hormone stimulation test in posttraumatic stress disorder. Biol. Psychiatry. 28:1990;657-664
35. Kudler H., Davidson J., Meador K., Lipper S., Ely T. The DST and posttraumatic stress disorder. Am. J. Psychiatry. 144:1987;1068-1071
36. Liberzon I., Lopez J.F., Flagel S.B., Vazquez D.M., Young E.A. Differential regulation of hippocampal glucocorticoid receptors mRNA and fast feedback: relevance to post-traumatic stress disorder. J. Neuroendocrinol. 11:1999;11-17
37. Marshall R.D., Garakani A. Psychobiology of the acute stress response and its relationship to the psychobiology of post-traumatic stress disorder. Psychiatr. Clin. North Am. 25:2002;385-395
38. Mason J.W., Giller E.L., Kosten T.R., Ostroff R.B., Podd L. Urinary free-cortisol levels in posttraumatic stress disorder patients. J. Nervous Mental Disord. 174:1986;145-149
39. McEwen B.S., Magarinos A.M. Stress effects on morphology and function of the hippocampus. Ann. N.Y. Acad. Sci. 821:1997;271-284
40. McFarlane A.C., Atchison M., Yehuda R. The acute stress response following motor vehicle accidents and its relation to PTSD. Ann. N.Y. Acad. Sci. 821:1997;437-441
41. Meaney M.J., Diorio J., Francis D., Widdowson J., LaPlante P., Caldji C., Sharma S., Seckl J.R., Plotsky P.M. Early environmental regulation of forebrain glucocorticoid receptor gene expression: implications for adrenocortical responses to stress. Dev. Neurosci. 18:1996;49-72
42. Newport D.J., Nemeroff C.B. Neurobiology of posttraumatic stress disorder. Curr. Opin. Neurobiol. 10:2000;211-218
43. Newport D.J., Heim C., Bonsall R., Miller A.H., Nemeroff C.B. Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse. Biol. Psychiatry. 55:2004;10-20
44. Penke Z., Felszeghy K., Fernette B., Sage D., Nyakas C., Burlet A. Postnatal maternal deprivation produces long-lasting modifications of the stress response, feeding and stress-related behaviour in the rat. Eur. J. Neurosci. 14:2001;747-755
45. Proulx K., Clavel S., Nault G., Richard D., Walker C.D. High neonatal leptin exposure enhances brain GR expression and feedback efficacy on the adrenocortical axis of developing rats. Endocrinology. 142:2001;4607-4616
46. Rolland J.P. Les techniques Psychologiques d'Evaluation des Personnes. Huteau M. Caractéristiques psychométriques d'un inventaire de réactions aux situations stressantes:le CISS de Endler & Parker. 1994;927-930 E.A.P, Paris
47. Saplosky R.M., Uno H., Rebert C.S., Finch C.E. Hippocampal damage associated with prolonged glucocorticoid exposure in primates. J. Neurosci. 10:1990;2897-2902
48. Smith M.A., Davidson J., Ritchie J.C., Kudler H., Lipper S., Chappell P., Nemeroff C.B. The corticotropin-releasing hormone test in patients with posttraumatic stress disorder. Biol. Psychiatry. 26:1989;349-355
49. Stein M.B., Yehuda R., Koverola C., Hanna C. Enhanced dexamethasone suppression of plasma cortisol in adult women traumatized by childhood sexual abuse. Biol. Psychiatry. 42:1997;680-686
50. Stokes P.E., Sikes C.R. Hypothalamic-pituitary-adrenal axis in affective disorders. Meltzer H.Y. Psychopharmacology: the Third Generation of Progress. 1987;589-607 Raven Press, New York
51. Vallee M., MacCari S., Dellu F., Simon H., Le Moal M., Mayo W. Long-term effects of prenatal stress and postnatal handling on age-related glucocorticoid secretion and cognitive performance: a longitudinal study in the rat. Eur. J. Neurosci. 11:1999;2906-2916
52. Waltman C., Blackman M.R., Chrousos G.P., Riemann C., Harman S.M. Spontaneous and glucocorticoid-inhibited adrenocorticotropic hormone and cortisol secretion are similar in healthy young and old men. J. Clin. Endocrinol. Metab. 73:1991;495-502
53. Wiedemann K., Holsboer F. The effect of dexamethasone dosage upon plasma cortisol and dexamethasone during the DST. J. Affect. Disord. 19:1990;133-137
54. Yehuda R. Neuroendocrinology. Nutt D., Davidson J.R.T., Zohar J. Post-traumatic Stress Disorder: Diagnosis, Management and Treatment. 2000;53-67 Martin Dunitz, London
55. Yehuda R. Current status of cortisol findings in post-traumatic stress disorder. Psychiatr. Clin. North Am. 25:2002;341-368
56. Yehuda R., Giller E.L., Southwick S.M., Lowy M.T., Mason J.W. Hypothalamic-pituitary-adrenal dysfunction in posttraumatic stress disorder. Biol. Psychiatry. 30:1991a;1031-1048
57. Yehuda R., Lowy M.T., Southwick S.M., Shaffer D., Giller E.L. Jr. Lymphocyte glucocorticoid receptor number in posttraumatic stress disorder. Am. J. Psychiatry. 148:1991b;499-504
58. Yehuda R., Boisoneau D., Lowy M.T., Giller E.L. Jr. Dose-response changes in plasma cortisol and lymphocyte glucocorticoid receptors following dexamethasone administration in combat veterans with and without posttraumatic stress disorder. Arch. Gen. Psychiatry. 52:1995;583-593
59. Yehuda R., Teicher M.H., Trestman R.L., Levengood R.A., Siever L.J. Cortisol regulation in posttraumatic stress disorder and major depression: a chronobiological analysis. Biol. Psychiatry. 40:1996;79-88
60. Yehuda R., Halligan S.L., Bierer L.M. Cortisol levels in adult offspring of Holocaust survivors: relation to PTSD symptom severity in the parent and child. Psychoneuroendocrinology. 27:2002;171-180
61. Young E.A., Kotun J., Haskett R.F., Grunhaus L., Greden J.F., Watson S.J., Akil H. Dissociation between pituitary and adrenal suppression to dexamethasone in depression. Arch. Gen. Psychiatry. 50:1993;395-403