Energy charge is not decreased in lymphocytes of patients with leber’s hereditary optic neuropathy with the 11778 mutation

Journal of Neuro-Ophthalmology

Volumn 18, Issue 2, 1998, Pages 84-85

  Yen, May Yung ^a   Lee, Jian Fu ^a   Liu, Jorn Hon ^a   Wei, Yau Huei ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Energy charge; Leber s hereditary optic neuropathy; Mitochondrial DNA mutation; Oxidative phosphorylation

Indexed keywords

EID: 84975518719     PISSN: 10708022     EISSN: 15365166     Source Type: Journal    
DOI: 10.1097/00041327-199806000-00002     Document Type: Article

References (10)

1. Wallace DC, Singh G, Lou MT, et al. Mitochondrial DNA mutation associated with Leber’s hereditary optic neuropathy. Science 1988; 242: 1427-30.
2. Newman NJ. Leber’s hereditary optic neuropathy: new genetic consideration. Arch Neurol 1993; 50: 540-8.
3. Larsson N-G, Anderson O, Holme R, Oldl’ors A, Wahlstrom J. Leber’s hereditary optic neuropathy and complex I deficiency in muscle. Ann Neurol 1991; 30: 701-8.
4. Mathews CK, Van Holde KE. Biochemistry. 2nd ed. Mcnlo Park, CA: The Benjamin/Cummings Publishing Co., 1996: 80.
5. Joshi RC, Kashima Y, Heller KB, Dao JT, Sadun AA. Pre- and postlaminar changes in nerve fibers of a rat model of mitochondrial optic neuropathy. Invest Ophthalmol Vis Sei 1995; 36(Suppl): 4883.
6. Lesseil S, Horovitz B. Histochemical study of enzymes of optic nerve of monkey and rat. Am J Ophthalmol 1972; 74: 118-26.
7. Ochs S. Local supply of energy required for fast axoplasmic transport. Proc Natl Acad Sei USA 1971; 68: 1279-82.
8. Sadun AA, Marione JF, Muci-Mendoza R, et al. Epidemic optic neuropathy in Cuba. Arch Ophthalmol 1994; 112: 691-9.
9. Joshi RC, Hsu HY, Kashima Y, Heller KB, Sherman J, Sadun AA. Mitochondrial changes in retinal receptor outer segments in a case of Leber’s hereditary optic neuropathy. Invest Ophthalmol Vis Sei 1996; 37(Suppl): 2271.
10. Sadun AA, Joshi RC, Sherman J. Comparing mitochondrial optic neuropathies: Leber’s hereditary and acquired optic neuropathies. Invest Ophthalmol Vis Sei 1996; 37(Suppl): 4239.