Prediction of human pharmacokinetics - Improving microsome-based predictions of hepatic metabolic clearance

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 10, 2007, Pages 1427-1431

  Fagerholm, Urban ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

ACCURACY; ACIDITY; ARTICLE; BINDING AFFINITY; BLOOD CELL; CONCENTRATION (PARAMETERS); CORRELATION ANALYSIS; DEFENSE MECHANISM; HUMAN; LIPOPHILICITY; LIVER CLEARANCE; MATHEMATICAL COMPUTING; MEASUREMENT; METHODOLOGY; MICROSOME; PERMEABILITY; PLASMA; PREDICTION; SCREENING;

EID: 35349020575     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.10.0014     Document Type: Article

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