Activation of rapid signaling pathways and the subsequent transcriptional regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root

Food and Chemical Toxicology

Volumn 45, Issue 12, 2007, Pages 2470-2478

  Dong, Sijun ^a   Inoue, Akio ^b   Zhu, Yun ^a   Tanji, Masao ^b   Kiyama, Ryoiti ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b InfoGenes Co Ltd   (Japan)

Author keywords

Akt; Erk1 2; Estrogenic activity; Glycyrrhiza glabra root; Glycyrrhizin; Signaling

Indexed keywords

COMPLEMENTARY DNA; ENZYME; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GLYCYRRHIZA GLABRA EXTRACT; GLYCYRRHIZIC ACID; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SULFORHODAMINE B;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER THERAPY; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA MICROARRAY; DRUG ACTIVITY; ESTROGEN ACTIVITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HORMONAL THERAPY; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; NUCLEOTIDE SEQUENCE; PLANT ROOT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; ESTRADIOL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GLYCYRRHIZA; GLYCYRRHIZIC ACID; HUMANS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

GLYCYRRHIZA GLABRA;

EID: 35348998912     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2007.05.031     Document Type: Article

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