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Volumn , Issue 16, 2007, Pages 2537-2540

Palladium-catalyzed reductive carbonylation of aryl triflates with synthesis gas

Author keywords

Aldehydes; Aryl triflates; Carbonylation; Homogenous catalysis; Palladium

Indexed keywords

4 METHOXYPHENYL TRIFLUOROMETHANESULFONATE; ALDEHYDE; CARBON MONOXIDE; HYDROGEN; PALLADIUM; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

EID: 35348980851     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-986662     Document Type: Article
Times cited : (37)

References (47)
  • 26
    • 13244268299 scopus 로고    scopus 로고
    • For a personal account, see
    • For a personal account, see: Zapf, A.; Beller, M. Chem. Commun. 2005, 431.
    • (2005) Chem. Commun , pp. 431
    • Zapf, A.1    Beller, M.2
  • 37
    • 0345030827 scopus 로고    scopus 로고
    • Aryl triflates were prepared from the corresponding phenols by a well-established method: Echavarren, A. M.; Stille, J. K. J. Am. Chem. Soc. 1987, 109, 5478.
    • Aryl triflates were prepared from the corresponding phenols by a well-established method: Echavarren, A. M.; Stille, J. K. J. Am. Chem. Soc. 1987, 109, 5478.
  • 38
    • 35348998661 scopus 로고    scopus 로고
    • A 50 mL round-bottom flask was charged with 4-methoxyphenol (1.86 g, 15 mmol) and sealed with a septum. Subsequently, pyridine (15 mL) was added. The clear solution was cooled to 0°C and trifluoromethanesulfonic anhydride (2.8 mL, 17 mmol) was added dropwise. The resulting orange solution was stirred over night at r.t. Another 10 mL Schlenk flask was charged with Pd(OAc)2 (50.5 mg, 1.5 mol, 1,3-bis(diphenylphosphino)propane (139.2 mg, 2.25 mol, DMF (5 mL, and 2-butoxyethyl ether (2.61 mL, internal GC standard, Both solutions were combined and transferred to a 100 mL autoclave of the 4560 series from Parr Instruments® under argon atmosphere. After flushing the autoclave three times with CO/H2 1:1, 20 bar of synthesis gas were adjusted at ambient temperature and the reaction was performed for 24 h at 100°C. Before and after the reductive carbonylation an aliquot of the reaction mixture was subjected to GC analysis for determination of yield and c
    • 2 (1:1), 20 bar of synthesis gas were adjusted at ambient temperature and the reaction was performed for 24 h at 100°C. Before and after the reductive carbonylation an aliquot of the reaction mixture was subjected to GC analysis for determination of yield and conversion.
  • 39
    • 33847712652 scopus 로고    scopus 로고
    • For previous work on palladium-catalyzed carbonylations of aryl halides applying CO, see for example: (a) Ashfield, L.; Barnard, C. F. J. Org. Process Res. Dev. 2007, 11, 39.
    • For previous work on palladium-catalyzed carbonylations of aryl halides applying CO, see for example: (a) Ashfield, L.; Barnard, C. F. J. Org. Process Res. Dev. 2007, 11, 39.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.