Asp125 and Thr130 in transmembrane domain 3 are major sites of α1b-adrenergic receptor antagonist binding

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 10, 2007, Pages 1891-1894

  Takahashi, Kazuya ^a   Hossain, Murad ^a   Ahmed, Maruf ^b   Bhuiyan, Mohiuddin Ahmed ^a   Ohnuki, Toshio ^a   Nagatomo, Takafumi ^a  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b UNIVERSITY OF RAJSHAHI   (Bangladesh)

Author keywords

1b adrenergic receptor receptor; Binding site; Mutagenesis; Prazosin

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; ALANINE; ALPHA 1B ADRENERGIC RECEPTOR ANTAGONIST; ASPARTIC ACID; INOSITOL PHOSPHATE; KETANSERIN; NIGULDIPINE; PHENYLEPHRINE; PRAZOSIN; RADIOLIGAND; TAMSULOSIN; THREONINE; TRITIUM; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG BINDING; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ADRENERGIC ALPHA-ANTAGONISTS; ALANINE; ASPARTIC ACID; BINDING, COMPETITIVE; BLOTTING, WESTERN; CELLS, CULTURED; DNA, COMPLEMENTARY; HUMANS; HYDROLYSIS; LIGANDS; MODELS, MOLECULAR; PHOSPHATIDYLINOSITOLS; PRAZOSIN; RECEPTORS, ADRENERGIC, ALPHA-1; THREONINE; TRANSFECTION;

EID: 35348947909     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.1891     Document Type: Article

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