Binding and functional affinity of sarpogrelate, its metabolite M-1 and ketanserin for human recombinant alpha-1-adrenoceptor subtypes

Pharmacology

Volumn 65, Issue 2, 2002, Pages 69-73

  Israilova, Malika ^a   Suzuki, Fumiko ^a   Tanaka, Takashi ^a   Nagatomo, Takafumi ^a   Taniguchi, Takanobu ^a   Muramatsu, Ikunobu ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

1 Adrenoceptors; 5 HT2receptor; Inositol phosphates; Radioligand binding assay; Sarpogrelate

Indexed keywords

1 [2 [2 (3 METHOXYPHENYL)ETHYL]PHENOXY] 3 (DIMETHYLAMINO) 2 PROPANOL; ALPHA 1 ADRENERGIC RECEPTOR; DRUG METABOLITE; INOSITOL PHOSPHATE; KETANSERIN; PHENYLEPHRINE; PRAZOSIN; RECEPTOR SUBTYPE; SARPOGRELATE; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HUMANS; KETANSERIN; PHENYLEPHRINE; PRAZOSIN; PROPANOLAMINES; RECEPTORS, ADRENERGIC, ALPHA-1; SEROTONIN ANTAGONISTS; SUCCINATES; TRITIUM;

EID: 0036216159     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000056189     Document Type: Article

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