Inhibitors targeting hepatocyte growth factor receptor and their potential therapeutic applications

Expert Opinion on Therapeutic Patents

Volumn 17, Issue 9, 2007, Pages 1035-1045

  Cui, Jingrong Jean ^a  

^a PFIZER INC   (United States)

Author keywords

c Met; Hepatocyte growth factor; Hepatocyte growth factor receptor; Metastasis; Proliferation; Receptor tyrosine kinase; Scatter factor; Vascular endothelial growth factor receptor

Indexed keywords

2 AMINO 3 BENZYLOXY 5 ARYLPYRIDINE; AMG 102; ARQ 197; CYCLOPROPANE DERIVATIVE; DASATINIB; ERLOTINIB; GEFITINIB; IMATINIB; K 252A; KRN 951; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY AMG 102; N [4 [(6,7 DIMETHOXY 4 QUINOLYL)OXY] 3 FLUOROPHENYL] N' (PHENYLACETYL)THIOUREA; PF 2341066; PHA 665752; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLO[3,2 C]PYRIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; QUINOLINE DERIVATIVE; SCATTER FACTOR RECEPTOR; SORAFENIB; STAT3 PROTEIN; SU 11274; SUNITINIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; XL 184; XL 880;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER THERAPY; CELL METABOLISM; CELL MOTILITY; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; DNA REPAIR; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; DRUG SELECTIVITY; ENZYME INHIBITION; GASTROINTESTINAL STROMAL TUMOR; HUMAN; HYPERTENSION; KIDNEY CARCINOMA; LUNG NON SMALL CELL CANCER; NONHUMAN; ONCOCYTOMA; PATENT; PROSTATE ADENOCARCINOMA; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

EID: 35348944483     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.17.9.1035     Document Type: Review

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