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Volumn 30, Issue 9, 2007, Pages 863-873

Beneficial effects of pioglitazone on left ventricular hypertrophy in genetically hypertensive rats

Author keywords

Left ventricular hypertrophy; Myofibroblast; Peroxisome proliferator activated receptor ; Spontaneously hypertensive rat; Thiazolidinedione

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGEN TYPE 3; CONNECTIVE TISSUE GROWTH FACTOR; GELATINASE A; GELATINASE B; GLUCOSE; INSULIN; MATRIX METALLOPROTEINASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 35348836050     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.30.863     Document Type: Article
Times cited : (26)

References (41)
  • 1
    • 6344256567 scopus 로고    scopus 로고
    • The biochemical response of the heart to hypertension and exercise
    • Wakatsuki T, Schlessinger J, Elson EL: The biochemical response of the heart to hypertension and exercise. Trends Biochem Sci 2004; 29: 609-617.
    • (2004) Trends Biochem Sci , vol.29 , pp. 609-617
    • Wakatsuki, T.1    Schlessinger, J.2    Elson, E.L.3
  • 2
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP: Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990; 322: 1561-1566.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 3
  • 4
    • 23944466382 scopus 로고    scopus 로고
    • Diastolic dysfunction in hypertensive hearts: Roles of perivascular inflammation and reactive myocardial fibrosis
    • Kai H, Kuwahara F, Tokuda K, Imaizumi T: Diastolic dysfunction in hypertensive hearts: roles of perivascular inflammation and reactive myocardial fibrosis. Hypertens Res 2005; 28: 483-490.
    • (2005) Hypertens Res , vol.28 , pp. 483-490
    • Kai, H.1    Kuwahara, F.2    Tokuda, K.3    Imaizumi, T.4
  • 5
    • 17844387158 scopus 로고    scopus 로고
    • Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction
    • Asai T, Kushiro T, Fujita H, Kanmatsuse K: Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction. Hypertens Res 2005; 28: 79-87.
    • (2005) Hypertens Res , vol.28 , pp. 79-87
    • Asai, T.1    Kushiro, T.2    Fujita, H.3    Kanmatsuse, K.4
  • 6
    • 0025297009 scopus 로고
    • Collagen and the myocardium: Fibrillar structure, biosynthesis and degradation in relation to hypertrophy and its regression
    • Eghbali M, Weber KT: Collagen and the myocardium: fibrillar structure, biosynthesis and degradation in relation to hypertrophy and its regression. Mol Cell Biochem 1990; 96: 1-14.
    • (1990) Mol Cell Biochem , vol.96 , pp. 1-14
    • Eghbali, M.1    Weber, K.T.2
  • 7
    • 33745202365 scopus 로고    scopus 로고
    • NADPH oxidase-dependent redox signaling in cardiac hypertrophy, remodeling and failure
    • Murdoch CE, Zhang M, Cave AC, Shah AM: NADPH oxidase-dependent redox signaling in cardiac hypertrophy, remodeling and failure. Cardiovasc Res 2006; 71: 208-215.
    • (2006) Cardiovasc Res , vol.71 , pp. 208-215
    • Murdoch, C.E.1    Zhang, M.2    Cave, A.C.3    Shah, A.M.4
  • 10
    • 0030602866 scopus 로고    scopus 로고
    • The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation
    • Schoonjans K, Staels B, Auwerx J: The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation. Biochim Biophys Acta 1996; 1302: 93-109.
    • (1996) Biochim Biophys Acta , vol.1302 , pp. 93-109
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 11
    • 7244227759 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors ligands, oxidative stress, and cardiac fibroblast extracellular matrix turnover
    • Villarreal FJ, Asbun J: Peroxisome proliferator-activated receptors ligands, oxidative stress, and cardiac fibroblast extracellular matrix turnover. Hypertension 2004; 44: 621-622.
    • (2004) Hypertension , vol.44 , pp. 621-622
    • Villarreal, F.J.1    Asbun, J.2
  • 12
    • 0037459356 scopus 로고    scopus 로고
    • PPARs of the heart: Three is a crowd
    • Kelly DP: PPARs of the heart: three is a crowd. Circ Res 2003; 92: 482-484.
    • (2003) Circ Res , vol.92 , pp. 482-484
    • Kelly, D.P.1
  • 13
    • 0037066014 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo
    • Asakawa M, Takano H, Nagai T, et al: Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo. Circulation 2002; 105: 1240-1246.
    • (2002) Circulation , vol.105 , pp. 1240-1246
    • Asakawa, M.1    Takano, H.2    Nagai, T.3
  • 14
    • 0035797865 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activators inhibit cardiac hypertrophy in cardiac myocytes
    • Yamamoto K, Ohki R, Lee RT, Ikeda U, Shimada K: Peroxisome proliferator-activated receptor-gamma activators inhibit cardiac hypertrophy in cardiac myocytes. Circulation 2001; 104: 1670-1675.
    • (2001) Circulation , vol.104 , pp. 1670-1675
    • Yamamoto, K.1    Ohki, R.2    Lee, R.T.3    Ikeda, U.4    Shimada, K.5
  • 15
    • 0036670238 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activators inhibit endothelin-1-related cardiac hypertrophy in rats
    • Sakai S, Miyauchi T, Irukayama-Tomobe Y, Ogata T, Goto K, Yamaguchi I: Peroxisome proliferator-activated receptor-gamma activators inhibit endothelin-1-related cardiac hypertrophy in rats. Clin Sci 2002; 103: 16-20.
    • (2002) Clin Sci , vol.103 , pp. 16-20
    • Sakai, S.1    Miyauchi, T.2    Irukayama-Tomobe, Y.3    Ogata, T.4    Goto, K.5    Yamaguchi, I.6
  • 16
    • 0036842574 scopus 로고    scopus 로고
    • Antiinflammatory and antiarteriosclerotic effects of pioglitazone
    • Ishibashi M, Egashira K, Hiasa K, et al: Antiinflammatory and antiarteriosclerotic effects of pioglitazone. Hypertension 2002; 40: 687-693.
    • (2002) Hypertension , vol.40 , pp. 687-693
    • Ishibashi, M.1    Egashira, K.2    Hiasa, K.3
  • 17
    • 0037058874 scopus 로고    scopus 로고
    • Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction
    • Shiomi T, Tsutsui H, Hayashidani S, et al: Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction. Circulation 2002; 106: 3126-3132.
    • (2002) Circulation , vol.106 , pp. 3126-3132
    • Shiomi, T.1    Tsutsui, H.2    Hayashidani, S.3
  • 18
    • 0141928168 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-α and receptor-γ activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension
    • Iglarz M, Touyz RM, Viel EC, et al: Peroxisome proliferator-activated receptor-α and receptor-γ activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension. Hypertension 2003; 42: 737-743.
    • (2003) Hypertension , vol.42 , pp. 737-743
    • Iglarz, M.1    Touyz, R.M.2    Viel, E.C.3
  • 19
    • 0038460061 scopus 로고    scopus 로고
    • The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction
    • Lygate CA, Hulbert K, Monfared M, Cole MA, Clarke K, Neubauer S: The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction. Cardiovasc Res 2003; 58: 632-637.
    • (2003) Cardiovasc Res , vol.58 , pp. 632-637
    • Lygate, C.A.1    Hulbert, K.2    Monfared, M.3    Cole, M.A.4    Clarke, K.5    Neubauer, S.6
  • 20
    • 10744225665 scopus 로고    scopus 로고
    • Peroxisome proliferator activated-receptor agonism and left ventricular remodeling in mice with chronic myocardial infarction
    • Frantz S, Hu K, Widder J, et al: Peroxisome proliferator activated-receptor agonism and left ventricular remodeling in mice with chronic myocardial infarction. Br J Pharmacol 2004; 141: 9-14.
    • (2004) Br J Pharmacol , vol.141 , pp. 9-14
    • Frantz, S.1    Hu, K.2    Widder, J.3
  • 21
    • 13544270029 scopus 로고    scopus 로고
    • Long-term effects of the PPAR gamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats
    • Diep QN, Amiri F, Benkirane K, Paradis P, Schiffrin EL: Long-term effects of the PPAR gamma activator pioglitazone on cardiac inflammation in stroke-prone spontaneously hypertensive rats. Can J Physiol Pharmacol 2004; 82: 976-985.
    • (2004) Can J Physiol Pharmacol , vol.82 , pp. 976-985
    • Diep, Q.N.1    Amiri, F.2    Benkirane, K.3    Paradis, P.4    Schiffrin, E.L.5
  • 22
    • 17544379019 scopus 로고    scopus 로고
    • Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium
    • Ide T, Tsutsui H, Kinugawa S, et al: Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium. Circ Res 2000; 86: 152-157.
    • (2000) Circ Res , vol.86 , pp. 152-157
    • Ide, T.1    Tsutsui, H.2    Kinugawa, S.3
  • 23
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Okhawa H, Ohishi N, Yagi N: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Okhawa, H.1    Ohishi, N.2    Yagi, N.3
  • 24
    • 0037076294 scopus 로고    scopus 로고
    • Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: Role of peroxisome proliferator-activated receptor-gamma
    • Diep QN, El Mabrouk M, Cohn JS, et al: Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma. Circulation 2002; 105: 2296-2302.
    • (2002) Circulation , vol.105 , pp. 2296-2302
    • Diep, Q.N.1    El Mabrouk, M.2    Cohn, J.S.3
  • 25
    • 3042733725 scopus 로고    scopus 로고
    • Direct effects of high glucose and insulin on protein synthesis in cultured cardiac myocytes and DNA and collagen synthesis in cardiac fibroblasts
    • Tokudome T, Horio T, Yoshihara F, et al: Direct effects of high glucose and insulin on protein synthesis in cultured cardiac myocytes and DNA and collagen synthesis in cardiac fibroblasts. Metabolism 2004; 53: 710-715.
    • (2004) Metabolism , vol.53 , pp. 710-715
    • Tokudome, T.1    Horio, T.2    Yoshihara, F.3
  • 26
    • 22844432105 scopus 로고    scopus 로고
    • Pioglitazone improves left ventricular diastolic function in patients with essential hypertension
    • Horio T, Suzuki M, Suzuki K, et al: Pioglitazone improves left ventricular diastolic function in patients with essential hypertension. Am J Hypertens 2005; 18: 949-957.
    • (2005) Am J Hypertens , vol.18 , pp. 949-957
    • Horio, T.1    Suzuki, M.2    Suzuki, K.3
  • 27
    • 0037155784 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Regulation and dysregulation in the failing heart
    • Spinale FG: Matrix metalloproteinases: regulation and dysregulation in the failing heart. Circ Res 2002; 90: 520-530.
    • (2002) Circ Res , vol.90 , pp. 520-530
    • Spinale, F.G.1
  • 28
    • 20744441519 scopus 로고    scopus 로고
    • Gα12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts
    • Fujii T, Onohara N, Maruyama Y, et al: Gα12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. J Biol Chem 2005; 280: 23041-23047.
    • (2005) J Biol Chem , vol.280 , pp. 23041-23047
    • Fujii, T.1    Onohara, N.2    Maruyama, Y.3
  • 29
    • 1542343906 scopus 로고    scopus 로고
    • Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation
    • Grotendorst GR, Rahmanie H, Duncan MR: Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation. FASEB J 2004; 18: 469-479.
    • (2004) FASEB J , vol.18 , pp. 469-479
    • Grotendorst, G.R.1    Rahmanie, H.2    Duncan, M.R.3
  • 30
    • 0029808645 scopus 로고    scopus 로고
    • A novel transforming growth factor β response element controls the expression of the connective tissue growth factor gene
    • Grotendorst GR, Okochi H, Hayashi N: A novel transforming growth factor β response element controls the expression of the connective tissue growth factor gene. Cell Growth Differ 1996; 7: 469-480.
    • (1996) Cell Growth Differ , vol.7 , pp. 469-480
    • Grotendorst, G.R.1    Okochi, H.2    Hayashi, N.3
  • 31
    • 0032873465 scopus 로고    scopus 로고
    • Connective tissue growth factor mediates transforming growth factor β-induced collagen synthesis: Down-regulation by cAMP
    • Duncan MR, Frazier KS, Abramson S, et al: Connective tissue growth factor mediates transforming growth factor β-induced collagen synthesis: down-regulation by cAMP. FASEB J 1999; 13: 1774-1786.
    • (1999) FASEB J , vol.13 , pp. 1774-1786
    • Duncan, M.R.1    Frazier, K.S.2    Abramson, S.3
  • 32
    • 10744230225 scopus 로고    scopus 로고
    • Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways
    • Finckenberg P, Inkinen K, Ahonen J, et al: Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways. Am J Pathol 2003; 163: 355-366.
    • (2003) Am J Pathol , vol.163 , pp. 355-366
    • Finckenberg, P.1    Inkinen, K.2    Ahonen, J.3
  • 33
    • 18844387660 scopus 로고    scopus 로고
    • Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism
    • Rodriguez-Vita J, Sanchez-Lopez E, Esteban V, Ruperez M, Egido J, Ruiz-Ortega M: Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism. Circulation 2005; 111: 2509-2517.
    • (2005) Circulation , vol.111 , pp. 2509-2517
    • Rodriguez-Vita, J.1    Sanchez-Lopez, E.2    Esteban, V.3    Ruperez, M.4    Egido, J.5    Ruiz-Ortega, M.6
  • 34
    • 3242806007 scopus 로고    scopus 로고
    • TGF-beta1 and angiotensin networking in cardiac remodeling
    • Rosenkranz S: TGF-beta1 and angiotensin networking in cardiac remodeling. Cardiovasc Res 2004; 63: 423-432.
    • (2004) Cardiovasc Res , vol.63 , pp. 423-432
    • Rosenkranz, S.1
  • 35
    • 13944283346 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and cardiovascular remodeling
    • Schiffrin EL: Peroxisome proliferator-activated receptors and cardiovascular remodeling. Am J Physiol Heart Circ Physiol 2005; 288: 1037-1043.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. 1037-1043
    • Schiffrin, E.L.1
  • 38
    • 0346122777 scopus 로고    scopus 로고
    • Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation
    • Mehta JL, Hu B, Chen J, Li D: Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation. Arterioscler Thromb Vasc Biol 2003; 23: 2203-2208.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 2203-2208
    • Mehta, J.L.1    Hu, B.2    Chen, J.3    Li, D.4
  • 39
    • 0346157985 scopus 로고    scopus 로고
    • Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity
    • Dobrian AD, Schriver SD, Khraibi AA, Prewitt RL: Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity. Hypertension 2004; 43: 48-56.
    • (2004) Hypertension , vol.43 , pp. 48-56
    • Dobrian, A.D.1    Schriver, S.D.2    Khraibi, A.A.3    Prewitt, R.L.4
  • 40
    • 7244229584 scopus 로고    scopus 로고
    • Angiotensin II regulation of collagen type I expression in cardiac fibroblasts: Modulation by PPAR-gamma ligand pioglitazone
    • Chen K, Chen J, Li D, Zhang X, Mehta JL: Angiotensin II regulation of collagen type I expression in cardiac fibroblasts: modulation by PPAR-gamma ligand pioglitazone. Hypertension 2004; 44: 655-661.
    • (2004) Hypertension , vol.44 , pp. 655-661
    • Chen, K.1    Chen, J.2    Li, D.3    Zhang, X.4    Mehta, J.L.5
  • 41
    • 0344304678 scopus 로고    scopus 로고
    • Thiazolidinedione use, fluid retention, and congestive heart failure: A consensus statement from the American Heart Association and American Diabetes Association
    • Nesto RW, Bell D, Borrow RO, et al: Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. Circulation 2003; 108: 2941-2948.
    • (2003) Circulation , vol.108 , pp. 2941-2948
    • Nesto, R.W.1    Bell, D.2    Borrow, R.O.3


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