Th1 or Th2 balance regulated by interaction between dendritic cells and NKT cells

Immunologic Research

Volumn 38, Issue 1-3, 2007, Pages 319-332

  Onoé, Kazunori ^a   Yanagawa, Yoshiki ^a   Minami, Keita ^a   Iijima, Norifumi ^a   Iwabuchi, Kazuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Anti cancer; CD40; Dendritic cells; Feedback regulation; IFN ; NKT cells; Th1 Th2

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD40 ANTIGEN; CYTOKINE; INTERLEUKIN 4;

ANTIGEN EXPRESSION; CELL INTERACTION; CELL STIMULATION; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; FEEDBACK SYSTEM; HUMAN; IMMUNE RESPONSE; IMMUNOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MODULATION; NATURAL KILLER T CELL; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ANIMALS; ANTIGENS, CD40; CELL COMMUNICATION; CYTOKINES; DENDRITIC CELLS; FEEDBACK, BIOCHEMICAL; GALACTOSYLCERAMIDES; KILLER CELLS, NATURAL; MICE; TH1 CELLS; TH2 CELLS;

EID: 35348828497     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12026-007-0011-5     Document Type: Conference Paper

References (40)

1. Stockinger B, Bourgeois C, Kassiotis G. CD4 memory T cells: functional differentiation and homeostasis. Immunol Rev 2006;211:39-48.
2. Diao H, Kon S, Iwabuchi K, Kimura C, Morimoto J, Ito D, Segawa T, Maeda M, Hamuro J, Nakayama T, Taniguchi M, Yagita H, Van Kaer L, Onoé K, Denhardt D, Rittling S, Uede T. Osteopontin as a mediator of NKT cell function in T cell mediated liver diseases. Immunity 2004;21(4):539-50.
3. Nakai Y, Iwabuchi K, Fujii S, Ishimori N, Watano K, Mishima T, Iwabuchi C, Tanaka S, Dashtsoodol N, Nakayama T, Taniguchi M, Miyake S, Yamamura T, Kitabatake A, Joyce S, Van Kaer L, Onoé K. Natural killer T cells accelerate atherogenesis in mice. Blood 2004;104(7):2051-9.
4. Hochrein H, O'Keeffe M, Luft T, Vandenabeele S, Grumont RJ, Maraskovsky E, Shortman K. Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells. J Exp Med 2000;192(6):823-33.
5. Miyamoto K, Miyake S, Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001;413(6855):531-4.
6. + T cells. J Immunol 1995;154(10):5071-9.
7. + T cells that promptly produce interleukin 4. Proc Natl Acad Sci USA 1995;92(25):11931-4.
8. Kikuchi K, Yanagwa Y, Aranami T, Iwabuchi C, Iwabuchi K, Onoé K. Tumour necrosis factor-α but not lipopolysaccharide enhances preference of murine dendritic cells for Th2 differentiation. Immunology 2003;108(1):42-9.
9. Iijima N, Yanagawa Y, Iwabuchi K, Onoé K. Selective regulation of CD40 expression in murine dendritic cells by thiol antioxidants. Immunology 2003;110(2):197-203.
10. Iijima N, Yanagawa Y, Onoé K. Role of early and late phase activation of p38 MAPK induced by TNF-α or 2, 4-dinitrobenzene during maturation of dendritic cells. Immunology 2003;110(3):322-8.
11. Minami K, Yanagawa Y, Iwabuchi K, Shinohara N, Harabayashi T, Nonomura K, Onoé K. Negative feed back regulation of T helper type 1 (Th1)/Th2 cytokine balance via dendritic cell and natural killer T cell interactions. Blood 2005;106(5):1685-93.
12. + NKT cells in development of Wegener's granulomatosis and relapsing polychondritis. Clin Exp Immunol 2004;136(3):591-600.
13. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 1991;9:271-96.
14. Banchereau J, Steinman RM. Dendritic cells and the control of innunity. Nature 1998;392 (6673): 245-51.
15. Yanagawa Y, Onoé K. CCL19 induces rapid dendritic extension of murine dendritic cells. Blood 2002;100(6):1948-56.
16. Yanagawa Y, Onoé K. CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities. Blood 2003;101(12):4923-9.
17. Iijima N, Yanagawa Y, Clingan JM, Onoé K. CCR7-mediated c-Jun N-terminal kinase activation regulates cell migration in mature dendritic cells. Int Immunol 2005;17(9):1201-12.
18. Yanagawa Y, Iijima N, Iwabuchi K, Onoé K. Activation of extracellular signal-related kinase by TNF-α controls the maturation and function of murine dendritic cells. J Leukoc Biol 2002;71(1):125-32.
19. Yanagawa Y, Onoé K. Distinct regulation of CD40-mediated interleukin (IL)-6 IL-12 production via mitogen-activated protein kinase (MAPK) and nuclear factor-κB-inducing kinase (NIK) in mature dendritic cells. Immunology 2006;117(4):526-35.
20. Shinkura R, Kitada K, Matsuda F, Tashiro K, Ikuta K, Suzuki M, Kogishi K, Serikawa T, Honjo T. Alymphoplasia is caused by a point mutation in the mouse gene encoding NF-κb-inducing kinase. Nat Genet 1999;22(1):74-7.
21. - single positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor Vβ family. Proc Natl Acad Sci USA 1992;89(14):6506-10.
22. - thymocytes with specific lymphokine secretion. Eur J Immunol 1993;23(1):307-10.
23. Terabe M, Matsui S, Noben-Trauth N, Chen H, Watson C, Donaldson DD, Carbone DP, Paul WE, Berzofsky JA. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4-STAT 6 pathway. Nat Immunol 2000;1(6):515-20.
24. + thymocyte population associated with intact Fas antigen expression on the target. J Exp Med 1994;180(2):423-32.
25. + thymocytes. J Immunol 1993;151(2):546-55.
26. + NK T cells in the early stages of embryogenesis. Proc Natl Acad Sci USA 1996;93(13):6516-20.
27. d. Proc Natl Acad Sci USA 1998;95(14):8199-204.
28. + T cells in the class I restricted TCR transgenic mice. Cell Immunol 2001;213(1):24-33.
29. - NK-like cells in the thymus. Blood 2001;97(11):1765-75.
30. + thymocytes associated with intact thymic structure. Proc Natl Acad Sci USA 1997;94(6):2472-7.
31. Konishi J, Iwabuchi K, Iwabuchi C, Ato M, Nagata J, Onoé K, Nakagawa K, Kasai M, Ogasawara K, Kawakami K, Onoé K. Thymic epithelial cells responsible for impaired generation of NK-T thymocytes in alymphoplasia mutant mice. Cell Immunol 2000;206(1):26-35.
32. Ross R. Atheroscherosis-an inflammatory disease. N Engl J Med 1999;340(2):115-26.
33. Ishimori N, Iwabuchi K, Fujii S, Watano K, Iwabuchi C, Ato M, Chiba H, Kitabatake A, Onoé K. Mixed allogeneic chimerism with wild-type strains ameliorated atherosclerosis in apoliprotein E-deficient mice. J Leukoc Biol 2001;69(5):732-40.
34. Kawano T, Cui J, Koezuka Y, Toura I, Kaneko Y, Motoki K, Ueno H, Nakagawa R, Sato H, Kondo E, Koseki H, Taniguchi M. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides. Science 1997;278(5343):1626-9.
35. Fujii S, Shimizu K, Kronenberg M, Steinman RM. Prolonged IFN-γ-producing NKT response induced with α-galactosylceramide- loaded DCs. Nat Immunol 2002;3(9):867-74.
36. Chang DH, Osman K, Connolly J, Kukreja A, Krasovsky J, Pack M, Hutchinson A, Geller M, Liu N, Annable R, Shay J, Kirchhoff K, Nishi N, Ando Y, Hayashi K, Hassoun H, Steinman RM, Dhodapkar MV. Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosylceramide loaded mature dendritic cells in cancer patients. J Exp Med 2005;201(9):1503-17.
37. Finkelman FD, Madden KB, Morris SC, Holmes JM, Boiani N, Katona IM, Maliszewski CR. Anticytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J Immunol 1993;151(3):1235-44.
38. Smyth MJ, Crowe NY, Pellicci DG, Kyparissoudis K, Kelly JM, Takeda K, Yagita H, Godfrey DI. Sequential production of interferon-γ by NK.1.1 (+) T cells and natural killer cells is essential for the antimetastatic effect of α-galactosylceramide. Blood 2002;99(4):1259-66.
39. Wilson M T, Singh A K, Van Kaer L. Immunotherapy with ligands of natural killer T cells. Trends Mol Med 2002;8(5):225-31.
40. Taniguchi M, Harada M, Kojo S, Nakayama T, Wakao H. The regulatory role of Vα 14 NKT cells in innate and acquired immune response. Annu Rev Immunol 2003;21:483-513.