Imaging of weak-source distributions in LSO-based small-animal PET scanners

Journal of Nuclear Medicine

Volumn 48, Issue 10, 2007, Pages 1692-1698

  Goertzen, Andrew L ^a,b   Joon, Young Suk ^b   Thompson, Christopher J ^b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Energy window; Intrinsic activity; Lutetium oxyorthosilicate; PET; Small animal PET

Indexed keywords

GERMANIUM 68; GERMANIUM DERIVATIVE; LUTETIUM OXYORTHOSILICATE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; IMAGE ANALYSIS; PHANTOM; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RADIODIAGNOSTIC EQUIPMENT AND SUPPLIES;

EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; IMAGE ENHANCEMENT; LUTETIUM; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SCATTERING, RADIATION; SENSITIVITY AND SPECIFICITY; SILICATES;

EID: 35348826758     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.040584     Document Type: Article

References (14)

1. Dahlbom M, Cherry SR, Eriksson L, Hoffman EJ, Wienhard K. Optimization of PET instrumentation for brain activation studies. IEEE Trans Nucl Sci. 1993;40:1048-1054.
2. Strother SC, Casey ME, Hoffman EJ. Measuring PET scanner sensitivity: relating count rates to image signal-to-noise ratios using noise equivalent counts. IEEE Trans Nucl Sci. 1990;37:783-788.
3. Turkington TG, Wilson JW, Colsher JG. Adjusting the low energy threshold for large bodies in PET. 2004 IEEE Nuclear Science Symposium Conference Record. 2004;5:2872-2876.
4. Watson CC, Casey ME, Bendriem B, et al. Optimizing injected dose in clinical PET by accurately modeling the counting-rate response functions specific to individual patient scans. J Nucl Med. 2005;46:1825-1834.
5. 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography. Proc Natl Acad Sci USA. 2002;99:3030-3035.
6. 124I-Labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice. J Nucl Med. 2003;44:1962-1969.
7. Humm JL, Rosenfeld A, Del Guerra A. From PET detectors to PET scanners. Eur J Nucl Med Mol Imaging. 2003;30:1574-1597.
8. Eriksson L, Watson CC, Wienhard K, et al. The ECAT HRRT: an example of NEMA scatter estimation issues for LSO-based PET systems. IEEE Trans Nucl Sci. 2005;52:90-94.
9. Watson CC, Casey ME, Eriksson L, Mulnix T, Adams D, Bendriem B. NEMA NU 2 performance tests for scanners with intrinsic radioactivity. J Nucl Med. 2004;45:822-826.
10. Yamamoto S, Horii H, Hurutani M, Matsumoto K, Senda M. Investigation of single, random, and true counts from natural radioactivity in LSO-based clinical PET. Ann Nucl Med. 2005;19:109-114.
11. Browne E, Junde H. Nuclear data sheets for A = 176. Nucl Data Sheets. 1998;84:337-486.
12. Knoess C, Siegel S, Smith A, et al. Performance evaluation of the microPET R4 PET scanner for rodents. Eur J Nucl Med Mol Imaging. 2003;30:737-747.
13. Laforest R, Longford D, Siegel S, Newport DF, Yap J. Performance evaluation of the microPET-Focus - F120. 2004 IEEE Nuclear Science Symposium Conference Record. 2004;5:2965-2969.
14. Daube-Witherspoon ME, Karp JS, Casey ME, et al. PET performance measurements using the NEMA NU 2-2001 standard. J Nucl Med. 2002;43:1398-1409.