Developments in the synovial biology field 2006

Arthritis Research and Therapy

Volumn 9, Issue 2, 2007, Pages

  Knedla, Anette ^a   Neumann, Elena ^a   Müller Ladner, Ulf ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE;

APOPTOSIS; B LYMPHOCYTE; BONE DEFECT; BONE DESTRUCTION; CARTILAGE DEGENERATION; CELL INTERACTION; CELL POPULATION; CELL SURVIVAL; CHRONIC INFLAMMATION; FIBROBLAST; HUMAN; INFLAMMATION; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; PATHOPHYSIOLOGY; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIUM; T LYMPHOCYTE; ANIMAL; IMMUNOLOGY; MACROPHAGE;

ANIMALS; ARTHRITIS, RHEUMATOID; B-LYMPHOCYTES; FIBROBLASTS; HUMANS; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MACROPHAGES; SYNOVIAL MEMBRANE; T-LYMPHOCYTES;

EID: 35148851664     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2140     Document Type: Review

References (80)

1. Smith M Barg E Weedon H Papangelis V Smeets T Tak PP Kraan M Coleman M Ahern M Microarchitecture and protective mechanisms in synovial tissue from clinically and arthro-scopically normal knee joints Ann Rheum Dis 2003, 62:303-307 1754505 12634226 10.1136/ard.62.4.303
2. Qu Z Garcia C O'Rourke L Planck S Kohli M Rosenbaum J Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining Arthritis Rheum 1994, 37:212-220 10.1002/art.1780370210 7510485
3. Kraan M Versendaal H Jonker M Bresnihan B Post W t Hart B Breedveld F Tak P Asymptomatic synovitis precedes clinically manifest arthritis Arthritis Rheum 1998, 41:1481-1488 10.1002/ 1529-0131(199808)41:8<1481::AID-ART19>3.0.CO;2-O 9704648
4. Paleolog EM Angiogenesis in rheumatoid arthritis Arthritis Res 2002, 4(Suppl 3): 81-90 10.1186/ar575
5. Roccaro A Russo F Cirulli T Di Pietro G Vacca A Dammacco F Antiangiogenesis for rheumatoid arthritis Curr Drug Targets Inflamm Allergy 2005, 4:27-30 10.2174/1568010053622911 15720232
6. Takemura S Braun A Crowson C Kurtin PJ Cofield RH O'Fallon WOM Goronzy JJ Weyand CM Lymphoid neogenesis in rheumatoid synovitis J Immunol 2001, 167:1072-1080 11441118
7. Karouzakis E Neidhart M Gay R Gay S Molecular and cellular basis of rheumatoid joint destruction Immunol Lett 2006, 106:8-13 10.1016/ j.imlet.2006.04.011 16824621
8. Steenvoorden M Tolboom T van der Pluijm G Lowik C Visser C Degroo tJ Gittenberger-Degroot A Deruiter M Wisse B Huizinga T Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics Arthritis Res Ther 2006, 8:R165-1794508 17076892 10.1186/ar2073
9. Berckmans RJ Nieuwland R Tak PP Boing AN Romijn FP Kraan MC Breedveld FC Hack CE Sturk A Cell-derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII-dependent mechanism Arthritis Rheum 2002, 46:2857-2866 10.1002/ art.10587 12428225
10. Distler J Pisetsky D Huber L Kalden J Gay S Distler O Microparticles as regulators of inflammation: Novel players of cellular crosstalk in the rheumatic diseases Arthritis Rheum 2005, 52:3337-3348 10.1002/art.21350 16255015
11. Distler J Huber L Gay S Distler O Pisetsky D Microparticles as mediators of cellular cross-talk in inflammatory disease Autoimmunity 2006, 39:683-690 10.1080/08916930601061538 17178565
12. Berckmans RJ Nieuwland R Kraan MC Schaap MC Pots D Smeets TJ Sturk A Tak PP Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes Arthritis Res Ther 2005, 7:R536-R544 1174949 15899040 10.1186/ar1706
13. Distler J Jüngel A Huber L Seemayer C Reich C Gay R Michel B Fontana A Gay S Pisetsky D The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles Proc Natl Acad Sci USA 2005, 102:2892-2897 548330 15701693 10.1073/pnas.0409781102
14. Biro E Nieuwland R Tak PP Pronk LM Schaap MC Sturk A Hack CE Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals Ann Rheum Dis 2007, 17261534
15. Joosten L Netea M Kim S Yoon D Oppers-Walgreen B Radstake T Barrera P van de Loo F Dinarello C van den Berg W IL-32, a proinflammatory cytokine in rheumatoid arthritis Proc Natl Acad Sci USA 2006, 103:3298-3303 1413916 16492735 10.1073/pnas.0511233103
16. Kim S Han S Azam T Yoon D Dinarello C Interleukin-32: A cytokine and inducer of TNFα Immunity 2005, 22:131-142 15664165
17. Magne D Palmer G Barton J Mezin F Talabot-Ayer D Bas S Duffy T Noger M Guerne P Nicklin M The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes Arthritis Res Ther 2006, 8:R80 1526623 16646978 10.1186/ar1946
18. Koenders M Lubberts E van de Loo F Oppers-Walgreen B van den Bersselaar L Helsen M Kolls J Di Padova F Joosten L van den Berg W Interleukin-17 acts independently of TNF-α under arthritic conditions J Immunol 2006, 176:6262-6269 16670337
19. Wei C Hsu Y Li H Wang Y Hsieh M Chen W Hsing C Chang M IL-20: Biological functions and clinical implications J Biomed Sci 2006, 13:601-612 10.1007/s11373-006-9087-5 16703417
20. Hsu Y Li H Hsieh M Liu M Huang K Chin L Chen P Cheng H Chang M Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis Arthritis Rheum 2006, 54:2722-2733 10.1002/ art.22039 16947773
21. Li J Shen W Kong K Liu Z Interleukin-21 induces T-cell activation and proinflammatory cytokine secretion in rheumatoid arthritis Scand J Immunol 2006, 64:515-522 10.1111/j.1365-3083.2006.01795.x 17032244
22. Antoniv T Ivashkiv L Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages Arthritis Rheum 2006, 54:2711-2721 10.1002/art.22055 16947381
23. Ehling A Schaffler A Herfarth H Tarner I Anders S Distler O Paul G Distler J Gay S Scholmerich J The potential of adiponectin in driving arthritis J Immunol 2006, 176:4468-4478 16547285
24. Senolt L Pavelka K Housa D Haluzik M Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis Cytokine 2006, 35:247-252 10.1016/j.cyto.2006.09.002 17079158
25. Senolt L Housa D Vernerova Z Jirasek T Svobodova R Veigl D Anderlova K Muller-Ladner U Pavelka K Haluzik M Resistin in rheumatoid arthritis synovial tissue, synovial fluid and serum Ann Rheum Dis 2007, 66:458-463 10.1136/ard.2006.054734 17040961
26. Gunaydin R Kaya T Atay A Olmez N Hur A Koseoglu M Serum leptin levels in rheumatoid arthritis and relationship with disease activity South Med J 2006, 99:1078-1083 17100028
27. Hizmetli S Kisa M Gokalp N Bakici M Are plasma and synovial fluid leptin levels correlated with disease activity in rheumatoid arthritis? Rheumatol Int 2007, 27:335-338 10.1007/s00296-006-0264-7 17102942
28. Vergunst CE van de Sande MGH Lebre MC Tak PP The role of chemokines in rheumatoid arthritis and osteoarthritis Scand J Rheumatol 2005, 34:415-425 10.1080/03009740500439159 16393761
29. Tarrant T Patel D Chemokines and leukocyte trafficking in rheumatoid arthritis Pathophysiology 2006, 13:1-14 10.1016/j.pathophys.2005.11.001 16380240
30. van Lieshout A van der Voort R le Blanc L Roelofs M Schreurs B van Riel P Adema G Radstake T Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, toll-like receptors and rheumatoid synovial fluid BMC Immunol 2006, 7:23 1590050 16984635 10.1186/1471-2172-7-23
31. Haringman J Smeets T Reinders-Blankert P Tak P Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis Ann Rheum Dis 2006, 65:294-300 10.1136/ ard.2005.037176 16107514
32. Meinecke I Rutkauskaite E Gay S Pap T The role of synovial fibroblasts in mediating joint destruction in rheumatoid arthritis Curr Pharm Des 2005, 11:563-568 10.2174/1381612053381945 15720275
33. Ospelt C Neidhart M Gay RE Gay S Synovial activation in rheumatoid arthritis Front Biosci 2004, 9:2323 -2334 15353290
34. Jang J Lim D-S Choi Y-E Jeong Y Yoo S-A Kim W-U Bae Y-S MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis Arthritis Res Ther 2006, 8:R170-1794514 17101062 10.1186/ar2079
35. Woods J Klosowska K Spoden D Stumbo N Paige D Scatizzi J Volin M Rao M Perlman H A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis Arthritis Res Ther 2006, 8:R113-1779389 16846525 10.1186/ar1999
36. Seemayer CA Kuchen S Neidhart M Kuenzler P Rihosková V Neumann E Pruschy M Aicher WK Möller-Ladner U Gay RE p53 in rheumatoid arthritis synovial fibroblasts at sites of invasion Ann Rheum Dis 2003, 62:1139-1144 1754413 14644850 10.1136/ard.2003.007401
37. Cha H Rosengren S Boyle D Firestein GS PUMA regulation and proapoptotic effects in fibroblast-like synoviocytes Arthritis Rheum 2006, 54:587-592 10.1002/art.21631 16447235
38. Connor A Berger S Narendam A Keystone E Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts Arthritis Res Ther 2006, 8:R94 1779395 16774691 10.1186/ar1968
39. Nagashima T Okazaki H Yudoh K Matsuno H Minota S Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: A potential therapeutic approach to rheumatoid arthritis Arthritis Rheum 2006, 54:579-586 10.1002/art.21564 16447234
40. Liu H Huang Q Shi B Eksarko P Temkin V Pope RM Regulation of Mcl-1 expression in rheumatoid arthritis synovial macrophages Arthritis Rheum 2006, 54:3174-3181 10.1002/art.22132 17009247
41. Liu H Eksarko P Temkin V Haines GR Perlman H Koch A Thimmapaya B Pope R Mcl-1 is essential for the survival of synovial fibroblasts in rheumatoid arthritis J Immunol 2005, 175:8337-8345 16339575
42. Wang J Li C Liu Y Mei W Yu S Zhang L Cao X Kimberly R Grizzle W Zhang H JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumornecrosis factor-α Am J Pathol 2006, 169:889-902 1698810 16936264 10.2353/ajpath.2006.051161
43. Hsu H Wu Y Mountz J Tumor necrosis factor ligand-receptor superfamily and arthritis Curr Dir Autoimmun 2006, 9:37-54 16394654
44. Huber L Distler O Tarner I Gay RE Gay S Pap T Synovial fibroblasts: Key players in rheumatoid arthritis Rheumatology 2006, 45:669-675 10.1093/ rheumatology/kel065 16567358
45. Zhu P Lu N Shi Z Zhou J Wu Z Yang Y Ding J Chen Z CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes Arthritis Res Ther 2006, 8:R44 1526600 16507143 10.1186/ar1899
46. Ainola MM Mandelin JA Liljeström MP Li T-F Hukkanen MVJ Konttinen YT Pannus invasion and cartilage degradation in rheumatoid arthritis: involvement of MMP-3 and interleukin-1β Clin Exp Rheumatol 2005, 23:644-650 16173240
47. Rutkauskaite E Volkmer D Shigeyama Y Schedel J Pap G Muller-Ladner U Meinecke I Alexander D Gay R Drynda S Retroviral gene transfer of an antisense construct against membrane type 1 matrix metalloproteinase reduces the invasiveness of rheumatoid arthritis synovial fibroblasts Arthritis Rheum 2005, 52:2010-2014 10.1002/art.21156 15986375
48. Bauer S Jendro M Wadle A Kleber S Stenner F Dinser R Reich A Faccin E Godde S Dinges H Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes Arthritis Res Ther 2006, 8:R171 1794515 17105646 10.1186/ar2080
49. Inoue T Boyle DL Corr M Hammaker D Davis RJ Flavell RA Firestein GS Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis Proc Natl Acad Sci USA 2006, 103:5484-5489 1459381 16567640 10.1073/pnas.0509188103
50. Ruocco MG Karin M IKKβ as a target for treatment of inflammation induced bone loss Ann Rheum Dis 2005, 64(Suppl 4):iV81 iv85 10.1136/ ard.2005.042721 16239395
51. Wen D Nong Y Morgan JG Gangurde P Bielecki A Dasilva J Keaveney M Cheng H Fraser C Schopf L A selective small molecule IκB kinase β inhibitor blocks nuclear factor κB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells J Pharmacol Exp Ther 2006, 317:989-1001 10.1124/jpet.105.097584 16525037
52. Schopf L Savinainen A Anderson K Kujawa J DuPont M Silva M Siebert E Chandra S Morgan J Gangurde P IKKβ inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis Arthritis Rheum 2006, 54:3163-3173 10.1002/art.22081 17009244
53. Neumann E Gay S Muller-Ladner U The RANK/RANKL/osteoprotegerin system in rheumatoid arthritis: New insights from animal models Arthritis Rheum 2005, 52:2960-2967 10.1002/art.21361 16200575
54. Shigeyama Y Pap T Kunzler P Simmen B Gay RE Gay S Expression of osteoclast differentiation factor in rheumatoid arthritis Arthritis Rheum 2000, 43:2523- 2530 10.1002/ 1529-0131(200011)43:11<2523::AID-ANR20>3.0.CO;2-Z 11083276
55. Lee H Jeon H Song E Han M Park S Lee S Yun H Kim J Kim J Lee Y CD40 ligation of rheumatoid synovial fibroblasts regulates RANKL-mediated osteoclastogenesis: Evidence of NF-κB-dependent, CD40-mediated bone destruction in rheumatoid arthritis Arthritis Rheum 2006, 54:1747-1758 10.1002/art.21873 16736517
56. Pettit A Walsh N Manning C Goldring S Gravallese E RANKL protein is expressed at the pannus - bone interface at sites of articular bone erosion in rheumatoid arthritis Rheumatology 2006, 45:1068-1076 10.1093/ rheumatology/kel045 16490750
57. Ma Y Pope RM The role of macrophages in rheumatoid arthritis Curr Pharm Des 2005, 11:569-580 10.2174/1381612053381927 15720276
58. Miyata J Tani K Sato K Otsuka S Urata T Lkhagvaa B Furukawa C Sano N Sone S Cathepsin G: The significance in rheumatoid arthritis as a monocyte chemoattractant Rheumatol Int 2007, 27:375-382 10.1007/ s00296-006-0210-8 16977463
59. Gregory J Morand E McKeown S Ralph J Hall P Yang Y McColl S Hickey M Macrophage migration inhibitory factor induces macrophage recruitment via CC chemokine ligand 2 J Immunol 2006, 177:8072-8079 17114481
60. Beech J Andreakos E Ciesielski C Green P Foxwell B Brennan F T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB: Implications for rheumatoid arthritis Arthritis Res Ther 2006, 8:R168-1794512 17101049 10.1186/ar2077
61. Toubi E Kessel A Slobodin G Boulman N Pavlotzky E Zisman D Rozenbaum M Rosner I Macrophage function changes following rituximab treatment in patients with rheumatoid arthritis Ann Rheum Dis 2006, 17148544
62. Adamopoulos I Sabokbar A Wordsworth B Carr A Ferguson D Athanasou N Synovial fluid macrophages are capable of osteoclast formation and resorption Am J Pathol 2006, 208:35-43 10.1002/path.1891
63. Komano Y Nanki T Hayashida K Taniguch K Miyasaka N Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts Arthritis Res Ther 2006, 8:R152 1779441 16987426 10.1186/ ar2046
64. Ando W Hashimoto J Nampei A Tsuboi H Tateishi K Ono T Nakamura N Ochi T Yoshikawa H Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis (CIA) J Bone Miner Metab 2006, 24:274-282 10.1007/s00774-006-0684-1 16816921
65. Paniagua RT Sharpe O Ho PP Chan SM Chang A Higgins JP Tomooka BH Thomas FM Song JJ Goodman SB Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis J Clin Invest 2006, 116:2633-2642 1564430 16981009
66. El Hajj Dib I Gallet M Mentaverri R Sevenet N Brazier M Kamel S Imatinib mesylate (Gleevec) enhances mature osteoclast apoptosis and suppresses osteoclast bone resorbing activity Eur J Pharmacol 2006, 551:27-33 10.1016/j.ejphar.2006.09.007 17049513
67. Leslie D Lipsky PE Notkins AL Autoantibodies as predictors of disease J Clin Invest 2001, 108:1417-1422 209428 11714731 10.1172/JCI200114452
68. Samuels J Ng YS Coupillaud C Paget D Meffre E Impaired early B cell tolerance in patients with rheumatoid arthritis J Exp Med 2005, 201:1659-1667 10.1084/jem.20042321 15897279
69. Keystone E B cell targeted therapies Arthritis Res Ther 2005, 7(Suppl 3):S13 -S18 10.1186/ar1738 15960817
70. Looney RJ B cell-targeted therapy for rheumatoid arthritis: An update on the evidence Drugs 2006, 66:625-639 10.2165/00003495-200666050-00004 16620141
71. Stohl W Therapeutic targeting of B lymphocyte stimulator (BLyS) in the rheumatic diseases Endocr Metab Immune Disord Drug Targets 2006, 6:351-358 17214581
72. Leipe J Skapenko A Lipsky PE Schulze-Koops H Regulatory T cells in rheumatoid arthritis Arthritis Res Ther 2005, 7:93-99 1174956 15899057 10.1186/ar1718
73. Skapenko A Leipe J Lipsky PE Schulze-Koops H The role of the T cell in autoimmune inflammation Arthritis Res Ther 2005, 7(Suppl 2):S4 -S14 10.1186/ar1703 15833146
74. Lawson C Brown A Bejarano V Douglas S Burgoyne C Greenstein A Boylston A Emery P Ponchel F Isaacs J Early rheumatoid arthritis is associated with a deficit in the CD4+CD25high regulatory T cell population in peripheral blood Rheumatology 2006, 45:1210-1217 10.1093/rheumatology/kel089 16571607
75. 4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease Immunol Rev 2006, 212:8-27 10.1111/j.0105-2896.2006.00427.x 16903903
76. Wan YY Flavell RA The roles for cytokines in the generation and maintenance of regulatory T cells Immunol Rev 2006, 212:114-130 10.1111/ j.0105-2896.2006.00407.x 16903910
77. +regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo Blood 2006, 108:1571-1579 10.1182/blood-2006-02-004747 16645171
78. +T regulatory cells with therapeutic effect in collagen-induced arthritis Arthritis Rheum 2006, 54:864-876 10.1002/art.21652 16508968
79. Hata H Sakaguchi N Yoshitomi H Iwakura Y Sekikawa K Azuma Y Kanai C Moriizumi E Nomura T Nakamura T Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice J Clin Invest 2004, 114:582-588 503774 15314695 10.1172/JCI200421795
80. + Th cells that cause autoimmune arthritis J Exp Med 2007, 204:41-47 10.1084/jem.20062259 17227914