Garlic extract reduces serum angiotensin converting enzyme (ACE) activity in nondiabetic and streptozotocin-diabetic rats

Pathophysiology

Volumn 14, Issue 2, 2007, Pages 109-112

  Hosseini, Mahmoud ^a,c   Shafiee, S Mohammad ^b   Baluchnejadmojarad, Tourandokht ^b  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Angiotensin coverting enzyme (ACE); Garlic extract; Peptidyl dipeptidase A; Streptozotocin diabetes

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GARLIC EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; GARLIC; GLUCOSE BLOOD LEVEL; MALE; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; STREPTOZOCIN DIABETES;

EID: 35148818035     PISSN: 09284680     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pathophys.2007.07.002     Document Type: Article

References (46)

1. Anderoli T.E., Carpenter C.C.J., Gariggs R.C., and Loscaizo J. Cecil Essential of Medicine (2004), Saunders, Philadelphia p. 583
2. Hardy G., Stanke-Labesque F., Poec'h M., Hakim A., Devillier P., Caron F., Morel S., Faure P., Halimi S., and Bessard G. Cysteinyl leukotrienes modulate angiotensin II constrictor effects on aortas from streptozotocin-induced diabetic rats. Arterioscler. Thromb. Vasc. Biol. 21 11 (2001) 1751-1758
3. Martinelli L., and Ceriello A. Mechanism of action of ACE-inhibitors and angiotensin receptor antagonists in diabetic nephropathy. Recent Prog. Med. 94 3 (2003) 131-135
4. Tsutsui H., Matsushima S., Kinugawa S., Ide T., Inoue N., Ohta Y., Yokota T., Hamaguchi S., and Sunagawa K. Angiotensin II type 1 receptor blocker attenuates myocardial remodeling and preserves diastolic function in diabetic heart. Hypertens. Res. 30 5 (2007) 439-449
5. Cooper S.A., Whaley-Connell A., Habibi J., Wei Y., Lastra G., Manrique C.M., Stas S., and Sowers J.R. Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance. Am. J. Physiol. Heart Circ. Physiol. June (22) (2007) (Epub ahead of print)
6. Mayhan W.G. Constrictor responses of the rat basilar artery during diabetes mellitus. Brain Res. 783 (1998) 326-331
7. Pieper G.M., and Siebeneich W. Temocapril, an angiotensin converting enzyme inhibitor, protects against diabetes induced endothelial dysfunction. Eur. J. Pharmacol. 403 1-2 (2000) 129-132
8. Mashour N.H., Lin G.J., and Frishman W.H. Herbal medicine for the treatment of cardiovascular disease. Arch. Intern. Med. 158 20 (1998) 2225-2234
9. Ayaz E., and Alpsoy H.C. Garlic (Allium sativum) and traditional medicine. Turkiye Parazitol Derg 31 2 (2007) 145-149
10. Hung K.C. The Pharmacologia of Chinese Herbes (1999), CRC Press, Florida p. 394
11. Katzung B.G. Basic & Clinical Pharmacology (2001), McGraw-Hill, New York p. 1092
12. Ozturk Y., Aydm S., Kosar M., and Can Baser K.H. Endothelium-dependent and independent effects of garlic on rat aorta. J. Ethnopharmacol. 44 2 (1994) 109-116
13. Pedraza-Chaverri J., TaPia E., Medina-campos O.N., Granados M., and Franco M. Garlic prevents hypertension induced by chronic inhibition of nitric oxide synthesis. Life Sci. 62 6 (1998) 71-77
14. Al-Qattan K.K., Alnaqeep M.A., and Ali M. The antihypertensive effect of garlic (Allium sativum) in the rat two-kidney-one-clip Goldblatt model. J. Ethnopharmacol. 66 2 (1999) 217-222
15. Sun X., and Ku D.D. Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats. Am. J. Physiol. Heart Circ. Physiol. 291 5 (2006) H2431-H2438
16. Koscielny J., Klussendorf D., Latza R., Schmitt R., Radtke H., Siegel G., and Kiesewetter H. The antiatherosclerotic effect of Allium sativum. Atherosclerosis 144 1 (1999) 237-246
17. Steiner M., and Lin R.S. Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract. J. Cardiovasc. Pharmacol. 31 6 (1998) 904-908
18. Wojcikowski K., Myers S., and Brooks L. Effects of garlic oil on platelet aggregation: a double-blind placebo-controlled crossover study. Platelets 18 1 (2007) 29-34
19. Isensee H., Rietz B., and Jacob R. Cardioprotective actions of garlic (Allium sativum). Arzneimittelforschung 43 2 (1993) 94
20. Rietz B., Isensee H., Strobach H., Makdessi S., and Jacob R. Cardioprotective actions of wild garlic (Allium ursinum) in ischemia and reperfusion. Mol. Cell. Biochem. 119 1-2 (1993) 143-150
21. Sharifi A.M., Darabi R., and Akbarloo N. Investigation of antihypertensive mechanism of garlic in 2K1c hypertensive rat. J. Ethnopharmacol. 86 2-3 (2003) 1-9
22. Budoff M. Aged garlic extract retards progression of coronary artery calcification. J. Nutr. 136 3 Suppl. (2006) 741S-744S
23. Orekhov A.N., and Tertov V.V. In vitro effect of garlic powder extract on lipid content in normal and atherosclerotic human aortic cells. Lipids 32 10 (1997) 1055-1060
24. Pantoja C.V., Chiang L.C., Norris B.C., and Concha J.B. Diuretic, natriuretic and antihypertensive effects produced by Allium sativum (garlic) in anesthetized dogs. J. Ethnopharmacol. 31 3 (1991) 325-331
25. Gorinstein S., Leontowicz M., Leontowicz H., Jastrzebski Z., Drzewiecki J., Namiesnik J., Zachwieja Z., Barton H., Tashma Z., Katrich E., and Trakhtenberg S. Dose-dependent influence of commercial garlic (Allium sativum) on rats fed cholesterol-containing diet. J. Agric. Food Chem. 54 11 (2006) 4022-4027
26. Irlbeck M., and Zimmer H.G. Functional responses of the left and right heart of diabetic rats to alpha- and beta-adrenergic receptor stimulation. Diabetes Res. Clin. Pract. 31 Suppl. (1996) S79-S86
27. Gupta S., Kataria M., Gupta P.K., Murganandan S., and Yashroy R.C. P rotective role of extracts of neem seeds in diabetes caused by streptozotocin in rats. J. Ethnopharmacol. 90 2-3 (2004) 185
28. Cushman D.W., and Cheung H.S. Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem. Pharmacol. 20 7 (1971) 1637-1648
29. Ahmed R.S., and Sharma S.B. Biochemical studies on combined effects of garlic and ginger in albino rats. Indian J. Exp. Biol. 35 8 (1997) 41-43
30. Patumraj S., Tewit S., Amatyakul S., Jariyapongskul A., Maneesri S., Kasantikul V., and Shepro D. Comparative effects of garlic and aspirinon diabetic cardiovascular complications. Drug Deliv. 7 2 (2000) 91
31. Mehrzia M., Ferid L., Mohamed A., and Ezzedine A. Acute effects of a partially purified fraction from garlic on plasma glucose and cholesterol levels in rats: putative involvement of nitric oxide. Indian J. Biochem. Biophys. 43 6 (2006) 386-390
32. Ali M., and Thomson M. Consumption of a garlic clove a day could be beneficial in preventing thrombosis. Prostaglandins Leukot. Essent. Fatty Acids 53 3 (1995) 211-212
33. Jain A.K., Vargas R., Gotzkowsky S., and McMahon F.G. Can garlic reduce levels of serum lipids? A controlled clinical study. Am. J. Med. 94 6 (1993) 632-635
34. Liu C.T., Wong P.L., Lii C.K., Hse H., and Sheen L.Y. Antidiabetic effect of garlic oil but not diallyl disulfide in rats with streptozotocin-induced diabetes. Food Chem. Toxicol. 44 8 (2006) 1377-1384
35. Augusti K.T., and Sheela C.G. Antiperoxide effect of S-allyl cysteine sulfoxide, an secretagogue, in diabetic rats. Experientia 52 2 (1996) 115-119
36. Sendl A., Elbl G., Steinke B., Redl K., Breu W., and Wagner H. Comparative phaemacological investigations of Allium ursinum and Allium sativum. Planta Med. 58 1 (1992) 1-7
37. Suetsuna K. Isolation and characterization of angiotensin I-converting enzyme inhibitor dipeptides derived from Allium sativum L. (garlic). J. Nutr. Biochem. 9 7 (1998) 415-419
38. Kowluru V., and Kowluru R.A. Increased oxidative stress in diabetes regulates activation of a small molecular weight G-protein, H-Ras, in the retina. Mol. Vis. 19 13 (2007) 602-610
39. Hayos D., Zieglar T., Bruner H.R., and Ruise J. Diabetes mellitus and vascular lesions. Metabolism 47 12 Suppl. 1 (1998) 16-19
40. Chen Y.H., Lin S.J., Lin F.Y., Wu T.C., Tsao C.R., Huang P.H., Liu P.L., Chen Y.L., and Chen J.W. High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stress-mediated mechanisms. Diabetes 56 6 (2007) 1559-1568
41. Giugliano D., Ceriello A., and Paolisso G. Oxidative stress and diabetic vascular complication. Diabetes Care 19 3 (1996) 257-267
42. Mcphee S.T., Lingappa V.R., and Ganong W.F. Pathophysiology of Disease (2000), McGraw-Hill pp. 439-454
43. Baluchnejadmojarad T., Roghani M., Homayounfar H., and Hosseini M. Beneficial effect of aqueous garlic extract on the vascular reactivity of streptozotocin-diabetic rats. J. Ethnopharmacol. 85 1 (2003) 139-144
44. Duggan K.A., Hodge G., Makarious M.M., and Charlesworth A.J. Renoprotective differences between prindopril and enalopril in the diabetic hypertensive rat do not reflect golmerular angiotensin-converting enzyme activity. Clin. Sci. (Lond.) 94 5 (1998) 511-551
45. Bjorck S., and Aurel M. Diabetes mellitus, rennin-angiotensin system, and angiotensin-converting enzym inhibition. Nephron 55 Suppl. 1 (1990) 10-20
46. Nicola W., Sidhom G., El Khyat Z., Ibrahim S., Salah A., and El Sayed A. Plasma angiotensin II, renin activity and serum angiotensin-converting enzyme activity in non-insulin dependent diabetes mellitus patients with diabetic nephropathy. Endocr. J. 48 1 (2001) 25-31