Application of recombinant DNA methods for production of cholinesterases as organophosphate antidotes and detectors

Arhiv za Higijenu Rada i Toksikologiju

Volumn 58, Issue 3, 2007, Pages 339-345

  Taylor, Palmer ^a   Reiner, Elsa ^b   Kovarik, Zrinka ^a,b   Radić, Zoran ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

Author keywords

Acetylcholinesterase; Fluorescent acetylcholinesterase; In situ click chemistry; Organophosphate inhibitors; Oxime antidotes; Oxime assisted catalysis; Reactivation kinetics; Remote detection; Template guided drug design

Indexed keywords

ACETYLCHOLINESTERASE; ANTIDOTE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; CYSTEINE; ORGANOPHOSPHATE; OXIME; RECOMBINANT DNA;

AMINO ACID SUBSTITUTION; CATALYSIS; CHEMICAL REACTION; CHEMISTRY; CONJUGATION; DNA SYNTHESIS; DNA TEMPLATE; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME REACTIVATION; ENZYME SYNTHESIS; MUTAGENESIS; MUTATION; REVIEW; STOICHIOMETRY; TOXICITY;

ANTIDOTES; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; DNA, RECOMBINANT; ORGANOPHOSPHORUS COMPOUNDS; OXIMES;

EID: 35148813176     PISSN: 00041254     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10004-007-0027-1     Document Type: Review

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