메뉴 건너뛰기




Volumn 24, Issue 10, 2007, Pages 829-850

Treatment strategies in elderly patients with multiple myeloma: Current status

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ACICLOVIR; ALPHA INTERFERON; BISPHOSPHONIC ACID DERIVATIVE; BORTEZOMIB; CARMUSTINE; CLODRONIC ACID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; ERYTHROPOIETIN; INTERFERON; LENALIDOMIDE; LOW MOLECULAR WEIGHT HEPARIN; MELPHALAN; MINERALOCORTICOID; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PAMIDRONIC ACID; PREDNISOLONE; RECOMBINANT ERYTHROPOIETIN; THALIDOMIDE; VINCRISTINE; WARFARIN; ZOLEDRONIC ACID;

EID: 35048882936     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-200724100-00004     Document Type: Review
Times cited : (3)

References (156)
  • 1
    • 3242777803 scopus 로고    scopus 로고
    • Advances in biology of multiple myeloma: Clinical applications
    • Hideshima T, Bergsagel PL, Kueh WM, et al. Advances in biology of multiple myeloma: clinical applications. Blood 2004; 104: 607-18
    • (2004) Blood , vol.104 , pp. 607-618
    • Hideshima, T.1    Bergsagel, P.L.2    Kueh, W.M.3
  • 3
    • 35048838099 scopus 로고    scopus 로고
    • American Cancer Society [online]. Available from URL: http://www.cancer.org [Accessed 2007 Jul 25]
    • American Cancer Society [online]. Available from URL: http://www.cancer.org [Accessed 2007 Jul 25]
  • 4
    • 30144443996 scopus 로고    scopus 로고
    • Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001
    • Morton ML, Wang SS, Devesa SS, et al. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood 2006; 107 (1): 265-75
    • (2006) Blood , vol.107 , Issue.1 , pp. 265-275
    • Morton, M.L.1    Wang, S.S.2    Devesa, S.S.3
  • 5
    • 33751025485 scopus 로고    scopus 로고
    • Autologous stem cell transplantation beyond 60 years of age
    • Jantunen E. Autologous stem cell transplantation beyond 60 years of age. Bone Marrow Transplant 2006; 38: 1-6
    • (2006) Bone Marrow Transplant , vol.38 , pp. 1-6
    • Jantunen, E.1
  • 7
    • 10544252687 scopus 로고    scopus 로고
    • Treatment of multiple myeloma in the elderly people: Long-term results in 178 patients
    • Blade J, Munoz M, Fontanillas M, et al. Treatment of multiple myeloma in the elderly people: long-term results in 178 patients. Age Ageing 1996; 25: 357-61
    • (1996) Age Ageing , vol.25 , pp. 357-361
    • Blade, J.1    Munoz, M.2    Fontanillas, M.3
  • 8
    • 0030322032 scopus 로고    scopus 로고
    • Multiple myeloma in the elderly: Clinical features and response to treatment in 113 patients
    • Clavio M, Casciaro S, Gatti A, et al. Multiple myeloma in the elderly: clinical features and response to treatment in 113 patients. Haematologica 1996; 81: 238-44
    • (1996) Haematologica , vol.81 , pp. 238-244
    • Clavio, M.1    Casciaro, S.2    Gatti, A.3
  • 9
    • 0031884645 scopus 로고    scopus 로고
    • Multiple myeloma in younger patients: The role of age as prognostic factor
    • Corso A, Klersy C, Lazzarino M, et al. Multiple myeloma in younger patients: the role of age as prognostic factor. Ann Hematol 1998; 76: 67-72
    • (1998) Ann Hematol , vol.76 , pp. 67-72
    • Corso, A.1    Klersy, C.2    Lazzarino, M.3
  • 10
    • 22144472629 scopus 로고    scopus 로고
    • The adverse prognostic impact of advance age in multiple myeloma
    • Mileshkin L, Prince M. The adverse prognostic impact of advance age in multiple myeloma. Leuk Lymphoma 2005; 46 (7): 951-66
    • (2005) Leuk Lymphoma , vol.46 , Issue.7 , pp. 951-966
    • Mileshkin, L.1    Prince, M.2
  • 11
    • 0025078298 scopus 로고
    • Multiple myeloma in the geriatric patient
    • Froom P, Quitt M, Aghai E. Multiple myeloma in the geriatric patient. Cancer 1990; 66: 965-7
    • (1990) Cancer , vol.66 , pp. 965-967
    • Froom, P.1    Quitt, M.2    Aghai, E.3
  • 12
    • 0021955684 scopus 로고
    • Age and the treatment of multiple myeloma: South Eastern Cancer Study Group experience
    • Cohen HJ, Bartoloucci A. Age and the treatment of multiple myeloma: South Eastern Cancer Study Group experience. Am J Med 1985; 79: 316-24
    • (1985) Am J Med , vol.79 , pp. 316-324
    • Cohen, H.J.1    Bartoloucci, A.2
  • 13
    • 26844556860 scopus 로고    scopus 로고
    • Multiple myeloma in elderly patients: Prognostic factors and outcome
    • Anagnostopoulos A, Gika D, Symeonidis A, et al. Multiple myeloma in elderly patients: prognostic factors and outcome. Eur J Haematol 2005; 75: 370-5
    • (2005) Eur J Haematol , vol.75 , pp. 370-375
    • Anagnostopoulos, A.1    Gika, D.2    Symeonidis, A.3
  • 14
    • 0024785771 scopus 로고
    • Treatment of multiple myeloma in old patients
    • Palva IP, Ahrenberg P, Ala-Harja K, et al. Treatment of multiple myeloma in old patients. Eur J Haematol 1989; 43: 328-31
    • (1989) Eur J Haematol , vol.43 , pp. 328-331
    • Palva, I.P.1    Ahrenberg, P.2    Ala-Harja, K.3
  • 15
    • 33644869566 scopus 로고    scopus 로고
    • Guidelines on the diagnosis and management of multiple myeloma 2005
    • Smith A, Wisloff F, Samson D. Guidelines on the diagnosis and management of multiple myeloma 2005. Br J Haematol 2005; 132: 410-51
    • (2005) Br J Haematol , vol.132 , pp. 410-451
    • Smith, A.1    Wisloff, F.2    Samson, D.3
  • 16
    • 0027397466 scopus 로고
    • Risk of disease progression in asymptomatic multiple myeloma
    • Dimopoulos MA, Moulopoulos A, Smith T, et al. Risk of disease progression in asymptomatic multiple myeloma. Am J Med 1993; 94: 57-61
    • (1993) Am J Med , vol.94 , pp. 57-61
    • Dimopoulos, M.A.1    Moulopoulos, A.2    Smith, T.3
  • 17
    • 6944235003 scopus 로고    scopus 로고
    • Drug therapy: Multiple myeloma
    • Kyle RA, Rajkumar S. Drug therapy: multiple myeloma. N Engl J Med 2004; 351 (18): 1860-73
    • (2004) N Engl J Med , vol.351 , Issue.18 , pp. 1860-1873
    • Kyle, R.A.1    Rajkumar, S.2
  • 18
    • 33646569840 scopus 로고    scopus 로고
    • Interactive computer program reveals current disease features and patterns of myeloma management [abstract]
    • Durie BG, Katz MS. Interactive computer program reveals current disease features and patterns of myeloma management [abstract]. Hematol J 2003; 4 Suppl. 1: S181
    • (2003) Hematol J , vol.4 , Issue.SUPPL. 1
    • Durie, B.G.1    Katz, M.S.2
  • 19
    • 0027523010 scopus 로고
    • Initial versus deferred melphalan-prednisolone therapy for asymptomatic multiple myeloma stage I: A randomised study
    • Hjorth M, Hellquist L, Holmberg E, et al. Initial versus deferred melphalan-prednisolone therapy for asymptomatic multiple myeloma stage I: a randomised study. Eur J Haematol 1993; 50: 95-102
    • (1993) Eur J Haematol , vol.50 , pp. 95-102
    • Hjorth, M.1    Hellquist, L.2    Holmberg, E.3
  • 20
    • 0034102430 scopus 로고    scopus 로고
    • Long term survival of stage I multiple myeloma given chemotherapy just after diagnosis or at progression of the disease: A multicenter randomised study. Cooperative Group Study and Treatment of Multiple Myeloma
    • Riccardi A, Mora O, Tinelli C, et al. Long term survival of stage I multiple myeloma given chemotherapy just after diagnosis or at progression of the disease: a multicenter randomised study. Cooperative Group Study and Treatment of Multiple Myeloma. Br J Cancer 2003; 82: 1254-60
    • (2003) Br J Cancer , vol.82 , pp. 1254-1260
    • Riccardi, A.1    Mora, O.2    Tinelli, C.3
  • 21
    • 0038236722 scopus 로고    scopus 로고
    • High dose therapy in multiple myeloma
    • Harousseau JL, Attal M. High dose therapy in multiple myeloma. Hematol J 2003; 4: 163-70
    • (2003) Hematol J , vol.4 , pp. 163-170
    • Harousseau, J.L.1    Attal, M.2
  • 22
    • 0032929769 scopus 로고    scopus 로고
    • Total therapy with tandem transplants for newly diagnosed multiple myeloma
    • Barlogie B, Jagannath S, Kesikan KR, et al. Total therapy with tandem transplants for newly diagnosed multiple myeloma. Blood 1999; 93: 55-65
    • (1999) Blood , vol.93 , pp. 55-65
    • Barlogie, B.1    Jagannath, S.2    Kesikan, K.R.3
  • 23
    • 0035103579 scopus 로고    scopus 로고
    • The impact of attaining a minimal disease state after high-dose melphalan and autologous transplantation for multiple myeloma
    • Davies FE, Forsyth PD, Rawstron AC, et al. The impact of attaining a minimal disease state after high-dose melphalan and autologous transplantation for multiple myeloma. Br J Haematol 2001; 112: 814-9
    • (2001) Br J Haematol , vol.112 , pp. 814-819
    • Davies, F.E.1    Forsyth, P.D.2    Rawstron, A.C.3
  • 24
    • 0034039018 scopus 로고    scopus 로고
    • Remission status defined by immunofixation vs electrophoresis after autologous transplantation has a major impact on outcome for multiple myeloma patients
    • Lahuerta JJ, Marinez-lopez J, De La Serna J, et al. Remission status defined by immunofixation vs electrophoresis after autologous transplantation has a major impact on outcome for multiple myeloma patients. Br J Haematol 2002; 109: 438-46
    • (2002) Br J Haematol , vol.109 , pp. 438-446
    • Lahuerta, J.J.1    Marinez-lopez, J.2    De La Serna, J.3
  • 25
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomised trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
    • Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomised trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. N Engl J Med 1996;335: 91-8
    • (1996) N Engl J Med , vol.335 , pp. 91-98
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 26
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-rescue for multiple myeloma
    • Child AJ, Gareth JM, Faith ED, et al. High-dose chemotherapy with hematopoietic stem-rescue for multiple myeloma. N Engl J Med 2003; 348 (19): 1875-9
    • (2003) N Engl J Med , vol.348 , Issue.19 , pp. 1875-1879
    • Child, A.J.1    Gareth, J.M.2    Faith, E.D.3
  • 27
    • 22644443235 scopus 로고    scopus 로고
    • A meta-analysis on data from 575 patients with multiple myeloma randomly assigned to either high-dose therapy or conventional therapy
    • Levy V, Katsahian S, Fernand JP, et al. A meta-analysis on data from 575 patients with multiple myeloma randomly assigned to either high-dose therapy or conventional therapy. Medicine 2005; 84 (4): 250-60
    • (2005) Medicine , vol.84 , Issue.4 , pp. 250-260
    • Levy, V.1    Katsahian, S.2    Fernand, J.P.3
  • 28
    • 33644824325 scopus 로고    scopus 로고
    • High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: Long term results of a randomized control trial from the Group Myelome-Autogreffe
    • Fernand J, Katsahian S, Marine D, et al. High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: long term results of a randomized control trial from the Group Myelome-Autogreffe. J Clin Oncol 2005; 36: 9227-33
    • (2005) J Clin Oncol , vol.36 , pp. 9227-9233
    • Fernand, J.1    Katsahian, S.2    Marine, D.3
  • 29
    • 0033566833 scopus 로고    scopus 로고
    • Dose intensive melphalan with stem cell support (MEL100) is superior to standard treatment in elderly myeloma patients
    • Palumbo A, Triolo S, Argentino C, et al. Dose intensive melphalan with stem cell support (MEL100) is superior to standard treatment in elderly myeloma patients. Blood 1999; 94: 1248-53
    • (1999) Blood , vol.94 , pp. 1248-1253
    • Palumbo, A.1    Triolo, S.2    Argentino, C.3
  • 30
    • 0034108261 scopus 로고    scopus 로고
    • The role of autologous transplantation in patients with multiple myeloma aged 65 years and over
    • Sirohi B, Powles R, Treleaven J, et al. The role of autologous transplantation in patients with multiple myeloma aged 65 years and over. Bone Marrow Transplant 2000; 25: 533-9
    • (2000) Bone Marrow Transplant , vol.25 , pp. 533-539
    • Sirohi, B.1    Powles, R.2    Treleaven, J.3
  • 31
    • 0030758629 scopus 로고    scopus 로고
    • Peripheral stem cell mobilization and engraftment in patients over 60 years of age
    • Guba SC, Vesole DH, Jagannath S, et al. Peripheral stem cell mobilization and engraftment in patients over 60 years of age. Bone Marrow Transplant 1997; 20: 1-3
    • (1997) Bone Marrow Transplant , vol.20 , pp. 1-3
    • Guba, S.C.1    Vesole, D.H.2    Jagannath, S.3
  • 32
    • 33646913813 scopus 로고    scopus 로고
    • 2) supported by autologous stem cell transplantation is safe and effective in elderly (≥65 years) myeloma patients: Comparison with younger patients treated within same protocol
    • 2) supported by autologous stem cell transplantation is safe and effective in elderly (≥65 years) myeloma patients: comparison with younger patients treated within same protocol. Bone Marrow Transplant 2006; 37: 917-22
    • (2006) Bone Marrow Transplant , vol.37 , pp. 917-922
    • Jantunen, E.1    Kuittinen, T.2    Penttila, K.3
  • 33
    • 28244477516 scopus 로고    scopus 로고
    • Cardiovascular toxicity is increased, but manageable during high-dose chemotherapy and autologous peripheral blood stem cell transplantation for patients aged 60 years and older
    • Mileshkin LR, Seymour JF, Wolf M, et al. Cardiovascular toxicity is increased, but manageable during high-dose chemotherapy and autologous peripheral blood stem cell transplantation for patients aged 60 years and older. Leuk Lymphoma 2005; 46 (11): 1575-9
    • (2005) Leuk Lymphoma , vol.46 , Issue.11 , pp. 1575-1579
    • Mileshkin, L.R.1    Seymour, J.F.2    Wolf, M.3
  • 34
    • 0034791513 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years
    • Badros A, Barglogie B, Seigel E, et al. Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years. Br J Haematol 2001; 114: 600-7
    • (2001) Br J Haematol , vol.114 , pp. 600-607
    • Badros, A.1    Barglogie, B.2    Seigel, E.3
  • 35
    • 0008893717 scopus 로고    scopus 로고
    • Peripheral blood progenitor cell collections in multiple myeloma: Predictors and management of inadequate collections
    • Prince HM, Imrie K, Stewart AK, et al. Peripheral blood progenitor cell collections in multiple myeloma: predictors and management of inadequate collections. Br J Haematol 1996; 93: 142-5
    • (1996) Br J Haematol , vol.93 , pp. 142-145
    • Prince, H.M.1    Imrie, K.2    Stewart, A.K.3
  • 36
    • 0028963248 scopus 로고
    • Peripheral blood stem cell transplants for multiple myeloma: Identification of favourable variables for rapid engraftment in 225 patients
    • Tricot G, Jagannath S, Vesole D, et al. Peripheral blood stem cell transplants for multiple myeloma: identification of favourable variables for rapid engraftment in 225 patients. Blood 1995; 85: 588-96
    • (1995) Blood , vol.85 , pp. 588-596
    • Tricot, G.1    Jagannath, S.2    Vesole, D.3
  • 37
    • 0032589065 scopus 로고    scopus 로고
    • 6/kg CD34+ cells for autologous stem cell transplantation significantly reduces febrile complications and the use of antibiotics after transplantation
    • 6/kg CD34+ cells for autologous stem cell transplantation significantly reduces febrile complications and the use of antibiotics after transplantation. Bone Marrow Transplant 1999; 23: 1177-81
    • (1999) Bone Marrow Transplant , vol.23 , pp. 1177-1181
    • Scheid, C.1    Draube, A.2    Reiser, M.3
  • 38
    • 8644260170 scopus 로고    scopus 로고
    • Intermediate-dose melphalan improves survival of myeloma patients aged 50 to 70: Results of a randomized control trial
    • Palumbo A, Bringhen S, Petrucci TM, et al. Intermediate-dose melphalan improves survival of myeloma patients aged 50 to 70: results of a randomized control trial. Blood 2004; 104: 3052-7
    • (2004) Blood , vol.104 , pp. 3052-3057
    • Palumbo, A.1    Bringhen, S.2    Petrucci, T.M.3
  • 39
    • 0026656725 scopus 로고
    • Primary dexamethasone treatment of multiple myeloma
    • Alexanian R, Dimopoulos MA, Delasalle K, et al. Primary dexamethasone treatment of multiple myeloma. Blood 1992; 80: 887-90
    • (1992) Blood , vol.80 , pp. 887-890
    • Alexanian, R.1    Dimopoulos, M.A.2    Delasalle, K.3
  • 40
    • 3242760702 scopus 로고    scopus 로고
    • First line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma
    • Cavo M, Zamagni E, Tosi P, et al. First line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma. Haematologica 2004; 89: 826-31
    • (2004) Haematologica , vol.89 , pp. 826-831
    • Cavo, M.1    Zamagni, E.2    Tosi, P.3
  • 41
    • 22044452126 scopus 로고    scopus 로고
    • Superiority of thalidomide and dexamethasone over vincristine doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma
    • Cavo M, Zamagni E, Tosii P, et al. Superiority of thalidomide and dexamethasone over vincristine doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood 2005; 106: 35-9
    • (2005) Blood , vol.106 , pp. 35-39
    • Cavo, M.1    Zamagni, E.2    Tosii, P.3
  • 42
    • 33644837094 scopus 로고    scopus 로고
    • Thalidomide and dexamethasone: A new standard of care for initial therapy in multiple myeloma
    • Richardson P, Anderson K. Thalidomide and dexamethasone: a new standard of care for initial therapy in multiple myeloma. J Clin Oncol 2006; 24: 334-6
    • (2006) J Clin Oncol , vol.24 , pp. 334-336
    • Richardson, P.1    Anderson, K.2
  • 43
    • 33644833147 scopus 로고    scopus 로고
    • Thalidomide and hematopoietic-cell transplantation for multiple myeloma
    • Barlogie B, Tricot G, Anaissie E, et al. Thalidomide and hematopoietic-cell transplantation for multiple myeloma. N Engl J Med 2006; 354: 1021-30
    • (2006) N Engl J Med , vol.354 , pp. 1021-1030
    • Barlogie, B.1    Tricot, G.2    Anaissie, E.3
  • 44
    • 0344076348 scopus 로고    scopus 로고
    • Combination chemotherapy versus melphalan plus prednisolone as treatment for multiple myeloma: An overview of 6,633 patients from 27 randomized trials
    • The Myeloma Trialists' Collaborative Group
    • The Myeloma Trialists' Collaborative Group. Combination chemotherapy versus melphalan plus prednisolone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. J Clin Oncol 1998; 16: 3832-42
    • (1998) J Clin Oncol , vol.16 , pp. 3832-3842
  • 45
    • 0023870374 scopus 로고
    • A randomized trial of maintenance vs no maintenance melphalan and prednisolone in responding multiple myeloma patients
    • Belch A, Shelley W, Bergsagel D, et al. A randomized trial of maintenance vs no maintenance melphalan and prednisolone in responding multiple myeloma patients. Br J Cancer 1988; 57: 94-9
    • (1988) Br J Cancer , vol.57 , pp. 94-99
    • Belch, A.1    Shelley, W.2    Bergsagel, D.3
  • 46
    • 14844319262 scopus 로고    scopus 로고
    • Toxicity in standard melphalan- prednisolone therapy among myeloma patients with renal failure: A retrospective analysis and recommendations for dose adjustments
    • Carlson K, Martin J, Knudsen L. Toxicity in standard melphalan- prednisolone therapy among myeloma patients with renal failure: a retrospective analysis and recommendations for dose adjustments. Br J Haematol 2005; 128: 631-5
    • (2005) Br J Haematol , vol.128 , pp. 631-635
    • Carlson, K.1    Martin, J.2    Knudsen, L.3
  • 47
    • 0026099489 scopus 로고
    • Multiple myeloma: VMCP/VBAP alternating combination chemotherapy is not superior to melphalan and prednisolone even in high risk patients
    • Boccadoro M, Marmont F, Tribalto M, et al. Multiple myeloma: VMCP/VBAP alternating combination chemotherapy is not superior to melphalan and prednisolone even in high risk patients. J Clin Oncol 1991; 9: 444-8
    • (1991) J Clin Oncol , vol.9 , pp. 444-448
    • Boccadoro, M.1    Marmont, F.2    Tribalto, M.3
  • 48
    • 0029664920 scopus 로고    scopus 로고
    • Binding of thalidomide to alpha-1-acid- glycoprotein may be involved in its inhibition of tumour necrosis factor alpha production
    • Turk BE, Jiang H, Lie JO. Binding of thalidomide to alpha-1-acid- glycoprotein may be involved in its inhibition of tumour necrosis factor alpha production. Proc Natl Acad Sci USA 1996; 93: 7552-6
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7552-7556
    • Turk, B.E.1    Jiang, H.2    Lie, J.O.3
  • 49
    • 0034331194 scopus 로고    scopus 로고
    • Thalidomide and its analogues overcome drug resistance of multiple myeloma cells to conventional therapy
    • Hideshima T, Chauhan D, Sima Y, et al. Thalidomide and its analogues overcome drug resistance of multiple myeloma cells to conventional therapy. Blood 2000; 96 (9): 2943-50
    • (2000) Blood , vol.96 , Issue.9 , pp. 2943-2950
    • Hideshima, T.1    Chauhan, D.2    Sima, Y.3
  • 50
    • 17944376919 scopus 로고    scopus 로고
    • Thalidomide for previously untreated indolent or smouldering multiple myeloma
    • Rajkumar S, Dispenzieri A, Fonseca R, et al. Thalidomide for previously untreated indolent or smouldering multiple myeloma. Leukemia 2001; 15: 1274-6
    • (2001) Leukemia , vol.15 , pp. 1274-1276
    • Rajkumar, S.1    Dispenzieri, A.2    Fonseca, R.3
  • 51
    • 0036843032 scopus 로고    scopus 로고
    • Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma
    • Rajkumar V, Hayman S, Gertz A, et al. Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma. J Clin Oncol 2002; 20: 4319-23
    • (2002) J Clin Oncol , vol.20 , pp. 4319-4323
    • Rajkumar, V.1    Hayman, S.2    Gertz, A.3
  • 52
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by Eastern Cooperative Oncology Group
    • Rajkumar V, Blood E, Vesole D, et al. Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by Eastern Cooperative Oncology Group. J Clin Oncol 2006; 24: 431-6
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, V.1    Blood, E.2    Vesole, D.3
  • 53
    • 29144480867 scopus 로고    scopus 로고
    • Combination therapy with thalidomide and dexamethasone in patients with newly diagnosed multiple myeloma not undergoing autologous stem cell transplant: A phase II trial
    • Dingli D, Rajkumar SV, Nowakowski G, et al. Combination therapy with thalidomide and dexamethasone in patients with newly diagnosed multiple myeloma not undergoing autologous stem cell transplant: a phase II trial. Haematologica 2005; 90 (12): 1650-4
    • (2005) Haematologica , vol.90 , Issue.12 , pp. 1650-1654
    • Dingli, D.1    Rajkumar, S.V.2    Nowakowski, G.3
  • 54
    • 0037208595 scopus 로고    scopus 로고
    • Thalidomide alone or with dexamethasone for previously untreated multiple myeloma
    • Weber D, Rankin K, Gavino M, et al. Thalidomide alone or with dexamethasone for previously untreated multiple myeloma. J Clin Oncol 2003; 21: 16-9
    • (2003) J Clin Oncol , vol.21 , pp. 16-19
    • Weber, D.1    Rankin, K.2    Gavino, M.3
  • 55
    • 33749361262 scopus 로고    scopus 로고
    • Thalidomide, dexamethasone, and pegylated liposomal doxorubicin (ThaDD) for patients older than 65 years with newly diagnosed multiple myeloma
    • Offidani M, Corvatta L, Maria-Novella P, et al. Thalidomide, dexamethasone, and pegylated liposomal doxorubicin (ThaDD) for patients older than 65 years with newly diagnosed multiple myeloma. Blood 2006; 108: 2159-64
    • (2006) Blood , vol.108 , pp. 2159-2164
    • Offidani, M.1    Corvatta, L.2    Maria-Novella, P.3
  • 56
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomised controlled trial
    • Palumbo A, Bringhen S, Caravito T, et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet 2006; 367: 825-31
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravito, T.3
  • 57
    • 35048823845 scopus 로고    scopus 로고
    • Facon T, Mary JY, Harousseau J, et al. Superiority of melphalan-prednisolone (MP) + thalidomide (THAL) over MP and autologous stem cell transplantation in the treatment of newly diagnosed elderly patients with multiple myeloma: Intergroupe Fracophone du Myeloma [abstract]. J Clin Oncol 2006; 24 (18S): 1
    • Facon T, Mary JY, Harousseau J, et al. Superiority of melphalan-prednisolone (MP) + thalidomide (THAL) over MP and autologous stem cell transplantation in the treatment of newly diagnosed elderly patients with multiple myeloma: Intergroupe Fracophone du Myeloma [abstract]. J Clin Oncol 2006; 24 (18S): 1
  • 58
    • 0035880229 scopus 로고    scopus 로고
    • Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: Identification of prognostic factors in a phase 2 study of 169 patients
    • Barlogie B, Diskan R, Eddlemon P, et al. Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients. Blood 2001; 98 (2): 492-4
    • (2001) Blood , vol.98 , Issue.2 , pp. 492-494
    • Barlogie, B.1    Diskan, R.2    Eddlemon, P.3
  • 59
    • 33947368197 scopus 로고    scopus 로고
    • An analysis of clinical trials assessing the efficacy and safety of single agent thalidomide in patients with relapsed or refractory multiple myeloma
    • Prince HM, Schenkel B, Mileshkin L. An analysis of clinical trials assessing the efficacy and safety of single agent thalidomide in patients with relapsed or refractory multiple myeloma. Leuk Lymphoma 2007; 48 (1): 46-55
    • (2007) Leuk Lymphoma , vol.48 , Issue.1 , pp. 46-55
    • Prince, H.M.1    Schenkel, B.2    Mileshkin, L.3
  • 60
    • 33644898842 scopus 로고    scopus 로고
    • A systematic review of phase II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma
    • Glasmacher A, Hahn C, Hoffmann F, et al. A systematic review of phase II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma. Br J Haematol 2005; 132: 584-93
    • (2005) Br J Haematol , vol.132 , pp. 584-593
    • Glasmacher, A.1    Hahn, C.2    Hoffmann, F.3
  • 61
    • 33750626750 scopus 로고    scopus 로고
    • Current status of new drugs for the treatment of patients with multiple myeloma
    • Kenealy M, Prince HM. Current status of new drugs for the treatment of patients with multiple myeloma. Int J Med 2006; 36: 1-9
    • (2006) Int J Med , vol.36 , pp. 1-9
    • Kenealy, M.1    Prince, H.M.2
  • 62
    • 0035469858 scopus 로고    scopus 로고
    • Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy
    • Zangari M, Anaissie E, Barlogie B. Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy. Blood 2001; 98: 1614-5
    • (2001) Blood , vol.98 , pp. 1614-1615
    • Zangari, M.1    Anaissie, E.2    Barlogie, B.3
  • 63
    • 28544451098 scopus 로고    scopus 로고
    • Thalidomide therapy and deep venous thrombosis in myeloma
    • Rajkumar S. Thalidomide therapy and deep venous thrombosis in myeloma. Mayo Clin Proc 2005; 80: 1564-74
    • (2005) Mayo Clin Proc , vol.80 , pp. 1564-1574
    • Rajkumar, S.1
  • 64
    • 33751074915 scopus 로고    scopus 로고
    • Myeloma, thalidomide and thrombosis
    • Honemann D, Prince HM. Myeloma, thalidomide and thrombosis. Leuk Lymphoma 2006; 47 (11): 2273-5
    • (2006) Leuk Lymphoma , vol.47 , Issue.11 , pp. 2273-2275
    • Honemann, D.1    Prince, H.M.2
  • 65
    • 0037216068 scopus 로고    scopus 로고
    • Response rate, durability of response and survival after thalidomide therapy for relapsed multiple myeloma
    • Kumar S, Gertz MA, Dispenzieri A, et al. Response rate, durability of response and survival after thalidomide therapy for relapsed multiple myeloma. Mayo Clin Proc 2003; 78: 34-9
    • (2003) Mayo Clin Proc , vol.78 , pp. 34-39
    • Kumar, S.1    Gertz, M.A.2    Dispenzieri, A.3
  • 66
    • 33749051832 scopus 로고    scopus 로고
    • Development of neuropathy in patients with myeloma treated with thalidomide: Patterns of occurrence and the role of electrophysiologic monitoring
    • Mileshkin L, Stark R, Day B, et al. Development of neuropathy in patients with myeloma treated with thalidomide: patterns of occurrence and the role of electrophysiologic monitoring. J Clin Oncol 2006; 27: 4507-14
    • (2006) J Clin Oncol , vol.27 , pp. 4507-4514
    • Mileshkin, L.1    Stark, R.2    Day, B.3
  • 67
    • 3042735765 scopus 로고    scopus 로고
    • Thalidomide for patients with relapsed multiple myeloma after high-dose chemotherapy and stem cell transplantation: Results of an open-label multicenter phase 2 study of efficacy, toxicity and biological activity
    • Richardson P, Schlossmann R, Jagannath S, et al. Thalidomide for patients with relapsed multiple myeloma after high-dose chemotherapy and stem cell transplantation: results of an open-label multicenter phase 2 study of efficacy, toxicity and biological activity. Mayo Clin Proc 2004; 79 (7): 875-82
    • (2004) Mayo Clin Proc , vol.79 , Issue.7 , pp. 875-882
    • Richardson, P.1    Schlossmann, R.2    Jagannath, S.3
  • 68
    • 33751094293 scopus 로고    scopus 로고
    • The troublesome toxicity of peripheral neuropathy with thalidomide
    • Mileshkin L, Prince HM. The troublesome toxicity of peripheral neuropathy with thalidomide. Leuk Lymphoma 2006; 47 (11): 2276-9
    • (2006) Leuk Lymphoma , vol.47 , Issue.11 , pp. 2276-2279
    • Mileshkin, L.1    Prince, H.M.2
  • 69
    • 0037245766 scopus 로고    scopus 로고
    • Durie BG. Low-dose thalidomide in myeloma: efficacy and biologic significance. Semin Oncol 2002; 29 (17S): 34-8
    • Durie BG. Low-dose thalidomide in myeloma: efficacy and biologic significance. Semin Oncol 2002; 29 (17S): 34-8
  • 70
    • 0035018156 scopus 로고    scopus 로고
    • Low dose thalidomide plus dexamethasone is an effective salvage therapy for advanced myeloma
    • Palumbo A, Giaccone L, Bertola A, et al. Low dose thalidomide plus dexamethasone is an effective salvage therapy for advanced myeloma. Haematologica 2001; 86: 399-403
    • (2001) Haematologica , vol.86 , pp. 399-403
    • Palumbo, A.1    Giaccone, L.2    Bertola, A.3
  • 71
    • 0036257544 scopus 로고    scopus 로고
    • Thalidomide in cancer treatment: A potential role in the elderly?
    • Zhou S, Kestell P, Tingle MD, et al. Thalidomide in cancer treatment: a potential role in the elderly? Drugs Aging 2002; 19 (2): 85-100
    • (2002) Drugs Aging , vol.19 , Issue.2 , pp. 85-100
    • Zhou, S.1    Kestell, P.2    Tingle, M.D.3
  • 72
    • 1842610155 scopus 로고    scopus 로고
    • Thalidomide in patients with myeloma and renal failure
    • Fakhouri F, Guerraoui H, Presne C, et al. Thalidomide in patients with myeloma and renal failure. Br J Haematol 2004; 125: 96-7
    • (2004) Br J Haematol , vol.125 , pp. 96-97
    • Fakhouri, F.1    Guerraoui, H.2    Presne, C.3
  • 73
    • 33748685797 scopus 로고    scopus 로고
    • Thalidomide and lenalidomide in multiple myeloma
    • Mazumder A, Jagannath S. Thalidomide and lenalidomide in multiple myeloma. Best Pract Res Clin Haematol 2006; 19 (4): 769-80
    • (2006) Best Pract Res Clin Haematol , vol.19 , Issue.4 , pp. 769-780
    • Mazumder, A.1    Jagannath, S.2
  • 74
    • 5144226782 scopus 로고    scopus 로고
    • Novel immunomodulatory therapies in the treatment of multiple myeloma
    • Anderson KC. Novel immunomodulatory therapies in the treatment of multiple myeloma. Oncology 2004; 18: 988-90
    • (2004) Oncology , vol.18 , pp. 988-990
    • Anderson, K.C.1
  • 76
    • 25844481422 scopus 로고    scopus 로고
    • Evaluating oral lenalidomide and dexamethasone versus placebo and dexamethasone in patients with relapsed or refractory multiple myeloma [abstract]
    • Dimopoulous M, Bweber D, Chen C, et al. Evaluating oral lenalidomide and dexamethasone versus placebo and dexamethasone in patients with relapsed or refractory multiple myeloma [abstract]. Haematologica 2005; 90 Suppl. 2: 160
    • (2005) Haematologica , vol.90 , Issue.SUPPL. 2 , pp. 160
    • Dimopoulous, M.1    Bweber, D.2    Chen, C.3
  • 77
    • 27744492561 scopus 로고    scopus 로고
    • Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma
    • Rajkumar SV, Hayman SR, Martha Q, et al. Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma. Blood 2005; 106: 4050-3
    • (2005) Blood , vol.106 , pp. 4050-4053
    • Rajkumar, S.V.1    Hayman, S.R.2    Martha, Q.3
  • 78
    • 35048892512 scopus 로고    scopus 로고
    • Weber D. Two phase III randomised double blind, placebo-controlled trials of lenalidomide-dexamethasone vs dexamethasone for refractory or relapsed multiple myeloma. Presented at a special session titled: ImiDs-results of phase III studies in relapsed/refractory myeloma [online]. Available from URL: http://www.ASCO.org [Accessed 2006 Nov 24]
    • Weber D. Two phase III randomised double blind, placebo-controlled trials of lenalidomide-dexamethasone vs dexamethasone for refractory or relapsed multiple myeloma. Presented at a special session titled: ImiDs-results of phase III studies in relapsed/refractory myeloma [online]. Available from URL: http://www.ASCO.org [Accessed 2006 Nov 24]
  • 79
    • 33646494190 scopus 로고    scopus 로고
    • Lenalidomide and venous thrombosis in multiple myeloma
    • Knight R, Delap JR, Zeldis BJ. Lenalidomide and venous thrombosis in multiple myeloma. N Engl J Med 2006; 354 (19): 2079-80
    • (2006) N Engl J Med , vol.354 , Issue.19 , pp. 2079-2080
    • Knight, R.1    Delap, J.R.2    Zeldis, B.J.3
  • 80
    • 35048830443 scopus 로고    scopus 로고
    • Phase III trial of lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone in newly diagnosed multiple myeloma (E4A03): A trial coordinated by the Eastern Cooperative Oncology Group [abstract]
    • Rajkumar SV, Jacobus S, Callander N, et al. Phase III trial of lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone in newly diagnosed multiple myeloma (E4A03): a trial coordinated by the Eastern Cooperative Oncology Group [abstract]. J Clin Oncol 2007; 25 (18 Suppl.): 8025a
    • (2007) J Clin Oncol , vol.25 , Issue.18 SUPPL.
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.3
  • 81
    • 35048851089 scopus 로고    scopus 로고
    • The role of lenalidomide in myeloma patients eligible for high dose therapy
    • Rajkumar SV. The role of lenalidomide in myeloma patients eligible for high dose therapy. Haematologica 2007; 92 Suppl. 2: 30-1
    • (2007) Haematologica , vol.92 , Issue.SUPPL. 2 , pp. 30-31
    • Rajkumar, S.V.1
  • 82
    • 0036240701 scopus 로고    scopus 로고
    • The proteasome: A novel target for cancer chemotherapy
    • Almond JB, Cohen GM. The proteasome: a novel target for cancer chemotherapy. Leukemia 2002; 16: 433-43
    • (2002) Leukemia , vol.16 , pp. 433-443
    • Almond, J.B.1    Cohen, G.M.2
  • 83
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, Richardson P, Chauhan D, et al. The proteasome inhibitor PS-341 inhibits growth induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001; 61: 3071-6
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3
  • 84
    • 21344469223 scopus 로고    scopus 로고
    • Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma
    • Jagannath S, Durie B, Wolf J, et al. Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma. Br J Haematol 2005; 129: 776-83
    • (2005) Br J Haematol , vol.129 , pp. 776-783
    • Jagannath, S.1    Durie, B.2    Wolf, J.3
  • 85
    • 33750953054 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: Results of an IFM phase II study
    • Harousseau JL, Attal M, Leleu X, et al. Bortezomib plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of an IFM phase II study. Haematologica 2006; 91: 1498-505
    • (2006) Haematologica , vol.91 , pp. 1498-1505
    • Harousseau, J.L.1    Attal, M.2    Leleu, X.3
  • 86
    • 21344435052 scopus 로고    scopus 로고
    • PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma
    • Oakervee HE, Popat R, Curry N, et al. PAD combination therapy (PS-341/bortezomib, doxorubicin and dexamethasone) for previously untreated patients with multiple myeloma. Br J Haematol 2005; 129: 755-62
    • (2005) Br J Haematol , vol.129 , pp. 755-762
    • Oakervee, H.E.1    Popat, R.2    Curry, N.3
  • 87
    • 35048875290 scopus 로고    scopus 로고
    • Cavenagh JK, Curry N, Stec J, et al. PAD therapy (bortezomib, doxorubicin, and dexamethasone) for untreated multiple myeloma (MM) [abstract]. J Clin Oncol 2004; 22 (14S): 6550a
    • Cavenagh JK, Curry N, Stec J, et al. PAD therapy (bortezomib, doxorubicin, and dexamethasone) for untreated multiple myeloma (MM) [abstract]. J Clin Oncol 2004; 22 (14S): 6550a
  • 88
    • 33748287079 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisolone in elderly untreated patients with multiple myeloma: Results of a multicenter phase 1/2 study
    • Mateos MV, Hernandez JM, Hernandez MT, et al. Bortezomib plus melphalan and prednisolone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study. Blood 2006; 108 (7): 2165-72
    • (2006) Blood , vol.108 , Issue.7 , pp. 2165-2172
    • Mateos, M.V.1    Hernandez, J.M.2    Hernandez, M.T.3
  • 89
    • 21344435666 scopus 로고    scopus 로고
    • Phase II trial of single agent bortezomib (Velcade) in patients with previously untreated multiple myeloma [abstract]
    • Richardson P, Chanan-Khan A, Schlossman R, et al. Phase II trial of single agent bortezomib (Velcade) in patients with previously untreated multiple myeloma [abstract]. Blood 2004; 104 (11): 336a
    • (2004) Blood , vol.104 , Issue.11
    • Richardson, P.1    Chanan-Khan, A.2    Schlossman, R.3
  • 90
    • 33746356913 scopus 로고    scopus 로고
    • A multicenter phase II trial of bortezomib in patients with previously untreated multiple myeloma: Efficacy with manageable toxicity in patients with unexpectedly high rates of baseline peripheral neuropathy [abstract]
    • Richardson P, Chanan-Khan A, Schlossman N, et al. A multicenter phase II trial of bortezomib in patients with previously untreated multiple myeloma: efficacy with manageable toxicity in patients with unexpectedly high rates of baseline peripheral neuropathy [abstract]. Blood 2005; 106: 2548a
    • (2005) Blood , vol.106
    • Richardson, P.1    Chanan-Khan, A.2    Schlossman, N.3
  • 91
    • 33645662389 scopus 로고    scopus 로고
    • Rapid control of previously untreated multiple myeloma with bortezomib-thalidomide-dexamethasone followed by early intensive therapy [abstract]
    • Wang M, Delasalle K, Alexanian R, et al. Rapid control of previously untreated multiple myeloma with bortezomib-thalidomide-dexamethasone followed by early intensive therapy [abstract]. Blood 2005; 106: 784a
    • (2005) Blood , vol.106
    • Wang, M.1    Delasalle, K.2    Alexanian, R.3
  • 92
    • 35048850944 scopus 로고    scopus 로고
    • Weekly bortezomib in the treatment of patients (pts) wtih previously treated multiple myeloma: A phase II trial of the Minnie Pearl Cancer Research Network [abstract]
    • Greco AF, Spigel RD, Barton JH, et al. Weekly bortezomib in the treatment of patients (pts) wtih previously treated multiple myeloma: a phase II trial of the Minnie Pearl Cancer Research Network [abstract]. J Clin Oncol 2006; 24 (18 Suppl.): 7547a
    • (2006) J Clin Oncol , vol.24 , Issue.18 SUPPL.
    • Greco, A.F.1    Spigel, R.D.2    Barton, J.H.3
  • 93
    • 33746343715 scopus 로고    scopus 로고
    • Weekly bortezomib with or without glucocorticosteroids is effective in patients with relapsed or refractory multiple myeloma [abstract]
    • Suvannasankha A, Smith A, Abonour R. Weekly bortezomib with or without glucocorticosteroids is effective in patients with relapsed or refractory multiple myeloma [abstract]. Blood 2005; 106: 2652a
    • (2005) Blood , vol.106
    • Suvannasankha, A.1    Smith, A.2    Abonour, R.3
  • 94
    • 35048830881 scopus 로고    scopus 로고
    • Moreau P, Coiteux C, Hulin T, et al. Prospective comparison of subcutaneous vs intravenous administration of bortezomib in patients with multiple myeloma: pharmacokinetics, efficacy and toxicity [abstract; poster no. 617]. XIth International Myeloma Workshop; 2007 Jun 25-30; Kos Island
    • Moreau P, Coiteux C, Hulin T, et al. Prospective comparison of subcutaneous vs intravenous administration of bortezomib in patients with multiple myeloma: pharmacokinetics, efficacy and toxicity [abstract; poster no. 617]. XIth International Myeloma Workshop; 2007 Jun 25-30; Kos Island
  • 95
    • 0034933036 scopus 로고    scopus 로고
    • Interferon as therapy for multiple myeloma: An individual patient data overview of 24 randomized trials and 4012 patients
    • Myeloma Trialists' Collaborative Group
    • Myeloma Trialists' Collaborative Group. Interferon as therapy for multiple myeloma: an individual patient data overview of 24 randomized trials and 4012 patients. Br J Haematol 2001; 113: 1020-34
    • (2001) Br J Haematol , vol.113 , pp. 1020-1034
  • 96
    • 7344264989 scopus 로고    scopus 로고
    • A randomised trial of maintenance interferon following high-dose chemotherapy in multiple myeloma: Long term follow up results
    • Cunningham D, Powles R, Malpas J, et al. A randomised trial of maintenance interferon following high-dose chemotherapy in multiple myeloma: long term follow up results. Br J Haematol 1998; 102: 495-502
    • (1998) Br J Haematol , vol.102 , pp. 495-502
    • Cunningham, D.1    Powles, R.2    Malpas, J.3
  • 97
    • 0036566201 scopus 로고    scopus 로고
    • Maintenance with alternate-day prednisolone improves survival in multiple myeloma patients
    • Berenson JR, Lichtenstein A, Porter L, et al. Maintenance with alternate-day prednisolone improves survival in multiple myeloma patients. Blood 2002; 99: 3163-8
    • (2002) Blood , vol.99 , pp. 3163-3168
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 98
    • 19944426090 scopus 로고    scopus 로고
    • Results of multicenter randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant
    • Stewart AK, Chen CI, Howson-Jan K, et al. Results of multicenter randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant. Clin Cancer Res 2004; 10: 8170-6
    • (2004) Clin Cancer Res , vol.10 , pp. 8170-8176
    • Stewart, A.K.1    Chen, C.I.2    Howson-Jan, K.3
  • 99
    • 33644825694 scopus 로고    scopus 로고
    • Maintenance treatment with thalidomide after autologous transplantation for myeloma: Final analysis of a prospective randomized study of the 'Intergroupe Francophone du Myelome' [abstract]
    • Attal M, Harousseau JL, Leyvraz S, et al. Maintenance treatment with thalidomide after autologous transplantation for myeloma: final analysis of a prospective randomized study of the 'Intergroupe Francophone du Myelome' [abstract]. Blood 2005; 106: 1148a
    • (2005) Blood , vol.106
    • Attal, M.1    Harousseau, J.L.2    Leyvraz, S.3
  • 100
    • 34548861112 scopus 로고    scopus 로고
    • First analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) trial of thalidomide and alternate day prednisolone following autologous stem cell transplantation (ASCT) for patients with multiple myeloma (ALLG MM6) [abstract]
    • Spencer A, Prince M, Roberts A, et al. First analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) trial of thalidomide and alternate day prednisolone following autologous stem cell transplantation (ASCT) for patients with multiple myeloma (ALLG MM6) [abstract]. Blood 2006; 108: 58a
    • (2006) Blood , vol.108
    • Spencer, A.1    Prince, M.2    Roberts, A.3
  • 101
    • 0023946023 scopus 로고    scopus 로고
    • Management of refractory myeloma: A review
    • Buzaid AC, Durie GM. Management of refractory myeloma: a review. J Clin Oncol 1998; 6: 889-905
    • (1998) J Clin Oncol , vol.6 , pp. 889-905
    • Buzaid, A.C.1    Durie, G.M.2
  • 102
    • 0019475513 scopus 로고
    • Chemoimmunotherapy for multiple myeloma
    • Alexanian R, Salmon S, Gutterman J, et al. Chemoimmunotherapy for multiple myeloma. Cancer 1981; 47: 1923-9
    • (1981) Cancer , vol.47 , pp. 1923-1929
    • Alexanian, R.1    Salmon, S.2    Gutterman, J.3
  • 103
    • 0021322023 scopus 로고
    • Effective treatment of advanced multiple myeloma refractory to alkylating agents
    • Barlogie B, Smith L, Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. N Engl J Med 1984; 310: 1353-6
    • (1984) N Engl J Med , vol.310 , pp. 1353-1356
    • Barlogie, B.1    Smith, L.2    Alexanian, R.3
  • 104
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • Richardson P, Sonneveld P, Schuster MW, et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 2005; 352 (24): 2487-98
    • (2005) N Engl J Med , vol.352 , Issue.24 , pp. 2487-2498
    • Richardson, P.1    Sonneveld, P.2    Schuster, M.W.3
  • 105
    • 33847373712 scopus 로고    scopus 로고
    • Lenalidomide plus high dose dexamethasone provides improved overall survival compared to high dose dexamethasone alone for relapsed or refractory multiple myeloma (MM): Results of 2 phase III studies (MM-009, MM-010) and subgroup analysis of patients with impaired renal function [abstract]
    • Weber D, Wang M, Chen C, et al. Lenalidomide plus high dose dexamethasone provides improved overall survival compared to high dose dexamethasone alone for relapsed or refractory multiple myeloma (MM): results of 2 phase III studies (MM-009, MM-010) and subgroup analysis of patients with impaired renal function [abstract]. Blood 2006; 108: 3547a
    • (2006) Blood , vol.108
    • Weber, D.1    Wang, M.2    Chen, C.3
  • 106
    • 0033056746 scopus 로고    scopus 로고
    • Early harvest and late transplantation as an effective therapeutic strategy in myeloma
    • Gertz MA, Lacy MQ, Inwards DJ, et al. Early harvest and late transplantation as an effective therapeutic strategy in myeloma. Bone Marrow Transplant 1999; 23: 221-6
    • (1999) Bone Marrow Transplant , vol.23 , pp. 221-226
    • Gertz, M.A.1    Lacy, M.Q.2    Inwards, D.J.3
  • 107
    • 0032748385 scopus 로고    scopus 로고
    • Antitumour activity of thalidomide in refractory multiple myeloma
    • Singhal S, Mehta J, Desikan R, et al. Antitumour activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999; 341: 1565-71
    • (1999) N Engl J Med , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 108
    • 0000367664 scopus 로고    scopus 로고
    • Thalidomide alone or with dexamethasone for multiple myeloma [abstract]
    • Weber DM, Gavino M, Delasalle K, et al. Thalidomide alone or with dexamethasone for multiple myeloma [abstract]. Blood 1999; 94: 604a
    • (1999) Blood , vol.94
    • Weber, D.M.1    Gavino, M.2    Delasalle, K.3
  • 109
    • 0034899464 scopus 로고    scopus 로고
    • Thalidomide and dexamethasone combination for refractory multiple myeloma
    • Dimopolous AM, Zervas K, Kouvatseas G, et al. Thalidomide and dexamethasone combination for refractory multiple myeloma. Ann Oncol 2001; 12: 991-5
    • (2001) Ann Oncol , vol.12 , pp. 991-995
    • Dimopolous, A.M.1    Zervas, K.2    Kouvatseas, G.3
  • 110
    • 4544386351 scopus 로고    scopus 로고
    • Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma
    • Palumbo A, Bertola A, Falco P, et al. Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma. Hematol J 2004; 5: 318-24
    • (2004) Hematol J , vol.5 , pp. 318-324
    • Palumbo, A.1    Bertola, A.2    Falco, P.3
  • 111
    • 0037495116 scopus 로고    scopus 로고
    • Thalidomide and dexamethasone for resistant multiple myeloma
    • Anagnostopoulos A, Weber D, Rankin K, et al. Thalidomide and dexamethasone for resistant multiple myeloma. Br J Haematol 2003; 121: 768-71
    • (2003) Br J Haematol , vol.121 , pp. 768-771
    • Anagnostopoulos, A.1    Weber, D.2    Rankin, K.3
  • 112
    • 0038305911 scopus 로고    scopus 로고
    • Multicenter phase 2 trial of thalidomide in relapsed/refractory multiple myeloma: Adverse prognostic impact of advanced age
    • Mileshkin L, Biagi JJ, Mitchell P, et al. Multicenter phase 2 trial of thalidomide in relapsed/refractory multiple myeloma: adverse prognostic impact of advanced age. Blood 2003; 102: 69-77
    • (2003) Blood , vol.102 , pp. 69-77
    • Mileshkin, L.1    Biagi, J.J.2    Mitchell, P.3
  • 114
    • 32544447241 scopus 로고    scopus 로고
    • Low-dose thalidomide with pegylated liposomal doxorubicin and high dose dexamethasone for relapsed/refractory multiple myeloma: A prospective, multicenter phase II study
    • Offidani M, Corvatta L, Marconi M, et al. Low-dose thalidomide with pegylated liposomal doxorubicin and high dose dexamethasone for relapsed/refractory multiple myeloma: a prospective, multicenter phase II study. Haematologica 2006; 91: 133-6
    • (2006) Haematologica , vol.91 , pp. 133-136
    • Offidani, M.1    Corvatta, L.2    Marconi, M.3
  • 115
    • 0035895104 scopus 로고    scopus 로고
    • Salvage therapy for multiple myeloma with thalidomide and CED chemotherapy
    • Moehler TM, Neben K, Benner A, et al. Salvage therapy for multiple myeloma with thalidomide and CED chemotherapy. Blood 2001; 98: 3846-8
    • (2001) Blood , vol.98 , pp. 3846-3848
    • Moehler, T.M.1    Neben, K.2    Benner, A.3
  • 116
    • 0041629471 scopus 로고    scopus 로고
    • DTPACE: An effective novel combination chemotherapy with thalidomide for previously treated patients with myeloma
    • Lee CK, Barlogie B, Munshi N, et al. DTPACE: an effective novel combination chemotherapy with thalidomide for previously treated patients with myeloma. J Clin Oncol 2003; 21: 2732-9
    • (2003) J Clin Oncol , vol.21 , pp. 2732-2739
    • Lee, C.K.1    Barlogie, B.2    Munshi, N.3
  • 117
    • 84988241358 scopus 로고    scopus 로고
    • International uniform response criteria for multiple myeloma
    • Durie BGM, Harousseau JL, Miguel JS, et al. International uniform response criteria for multiple myeloma. Leukemia 2006; 20: 1467-73
    • (2006) Leukemia , vol.20 , pp. 1467-1473
    • Durie, B.G.M.1    Harousseau, J.L.2    Miguel, J.S.3
  • 118
    • 33947383374 scopus 로고    scopus 로고
    • Assessing response rates in clinical trials of treatment for relapsed or refractory multiple myeloma: A study of bortezomib and thalidomide
    • Prince HM, Schenkel B, Mileshkin L. Assessing response rates in clinical trials of treatment for relapsed or refractory multiple myeloma: a study of bortezomib and thalidomide. Leukemia 2007; 21 (4): 818-20
    • (2007) Leukemia , vol.21 , Issue.4 , pp. 818-820
    • Prince, H.M.1    Schenkel, B.2    Mileshkin, L.3
  • 119
    • 33750607347 scopus 로고    scopus 로고
    • A randomised phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
    • Richardson GP, Blood E, Mitsiades SC, et al. A randomised phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Blood 2006; 108 (10): 3458-64
    • (2006) Blood , vol.108 , Issue.10 , pp. 3458-3464
    • Richardson, G.P.1    Blood, E.2    Mitsiades, S.C.3
  • 120
    • 1842619774 scopus 로고    scopus 로고
    • A multicenter, randomised, phase 2 study to evaluate the efficacy and safety of 2 CDC-5013 dose regimens when used alone or in combination with dexamethasone (dex) for the treatment of relapsed or refractory multiple myeloma (MM) [abstract]
    • Richardson PG, Jagannath S, Schlossman R, et al. A multicenter, randomised, phase 2 study to evaluate the efficacy and safety of 2 CDC-5013 dose regimens when used alone or in combination with dexamethasone (dex) for the treatment of relapsed or refractory multiple myeloma (MM) [abstract]. Blood 2003; 102: 825a
    • (2003) Blood , vol.102
    • Richardson, P.G.1    Jagannath, S.2    Schlossman, R.3
  • 121
    • 35048873735 scopus 로고    scopus 로고
    • Lenalidomide (L) in combination with dexamethasone (D) improves survival and time to progression in elderly patients (pts) with relapsed or refractory multiple myeloma [abstract]
    • Chanan-Khan AA, Weber D, Dimopolous M, et al. Lenalidomide (L) in combination with dexamethasone (D) improves survival and time to progression in elderly patients (pts) with relapsed or refractory multiple myeloma [abstract]. Blood 2006; 108: 3551a
    • (2006) Blood , vol.108
    • Chanan-Khan, A.A.1    Weber, D.2    Dimopolous, M.3
  • 122
    • 25844485097 scopus 로고    scopus 로고
    • A multicenter randomized parallel group double blind placebo controlled study of lenalidomide plus dexamethasone versus dexamethasone alone in previously treated subjects with multiple myeloma [abstract]
    • Weber DM, Chen C, Nievizky R, et al. A multicenter randomized parallel group double blind placebo controlled study of lenalidomide plus dexamethasone versus dexamethasone alone in previously treated subjects with multiple myeloma [abstract]. Haematologica 2005; 90 Suppl. 1: 155
    • (2005) Haematologica , vol.90 , Issue.SUPPL. 1 , pp. 155
    • Weber, D.M.1    Chen, C.2    Nievizky, R.3
  • 123
    • 33644816914 scopus 로고    scopus 로고
    • Study of lenalidomide plus dexamethasone versus dexamethasone alone in relapsed or refractory multiple myeloma (MM): Results of a phase 3 study (MM-010) [abstract]
    • Dimopoulos M, Spencer A, Attal M, et al. Study of lenalidomide plus dexamethasone versus dexamethasone alone in relapsed or refractory multiple myeloma (MM): results of a phase 3 study (MM-010) [abstract]. Blood 2005; 106 (11): 6a
    • (2005) Blood , vol.106 , Issue.11
    • Dimopoulos, M.1    Spencer, A.2    Attal, M.3
  • 124
    • 35048892891 scopus 로고    scopus 로고
    • Celgene Corporation. Revlimid (lenalidomide, package insert, Summit NJ, Celgene Corporation, 2006
    • Celgene Corporation. Revlimid (lenalidomide) [package insert]. Summit (NJ): Celgene Corporation, 2006
  • 126
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson P, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003; 348 (26): 2609-17
    • (2003) N Engl J Med , vol.348 , Issue.26 , pp. 2609-2617
    • Richardson, P.1    Barlogie, B.2    Berenson, J.3
  • 127
    • 5644250621 scopus 로고    scopus 로고
    • A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
    • Jagannath S, Barlogie, B, Berenson J, et al. A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br J Haematol 2004; 127: 165-72
    • (2004) Br J Haematol , vol.127 , pp. 165-172
    • Jagannath, S.1    Barlogie, B.2    Berenson, J.3
  • 128
    • 33746332717 scopus 로고    scopus 로고
    • Bortezomib continues demonstrates superior efficacy compared with high-dose dexamethasone in relapsed multiple myeloma: Updated results of the APEX trial [abstract]
    • Richardson P, Sonneveld P, Schuster M, et al. Bortezomib continues demonstrates superior efficacy compared with high-dose dexamethasone in relapsed multiple myeloma: updated results of the APEX trial [abstract]. Blood 2005; 106: 2547a
    • (2005) Blood , vol.106
    • Richardson, P.1    Sonneveld, P.2    Schuster, M.3
  • 129
    • 34447303363 scopus 로고    scopus 로고
    • Efficacy of single-agent bortezomib vs. single-agent thalidomide in patients with relapsed or refractory multiple myeloma: A systematic comparison
    • Prince HM, Adena M, Smith DK, et al. Efficacy of single-agent bortezomib vs. single-agent thalidomide in patients with relapsed or refractory multiple myeloma: a systematic comparison. Eur J Haematol 2007; 79: 93-9
    • (2007) Eur J Haematol , vol.79 , pp. 93-99
    • Prince, H.M.1    Adena, M.2    Smith, D.K.3
  • 130
    • 35048851088 scopus 로고    scopus 로고
    • Richardson P, Sonneveld P, Schuster M, et al. Safety and efficacy of bortezomib in high-risk and elderly patients with relapsed myeloma [abstract]. J Clin Oncol 2005; 23 (16S): 6533a
    • Richardson P, Sonneveld P, Schuster M, et al. Safety and efficacy of bortezomib in high-risk and elderly patients with relapsed myeloma [abstract]. J Clin Oncol 2005; 23 (16S): 6533a
  • 131
    • 35048878287 scopus 로고    scopus 로고
    • Jagannath S, Richardson P, Sonnoveld P, et al. Bortezomib appears to overcome poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials [abstract]. J Clin Oncol 2005; 23 (16S): 6501a
    • Jagannath S, Richardson P, Sonnoveld P, et al. Bortezomib appears to overcome poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials [abstract]. J Clin Oncol 2005; 23 (16S): 6501a
  • 132
    • 27644476353 scopus 로고    scopus 로고
    • Clinical factors predictive of outcome with bortezomib in patients with relapsed refractory multiple myeloma
    • Richardson P, Barlogie B, Berenson J, et al. Clinical factors predictive of outcome with bortezomib in patients with relapsed refractory multiple myeloma. Blood 2005; 106: 2977-81
    • (2005) Blood , vol.106 , pp. 2977-2981
    • Richardson, P.1    Barlogie, B.2    Berenson, J.3
  • 133
    • 31444442200 scopus 로고    scopus 로고
    • A practical update on the use of bortezomib in the management of multiple myeloma
    • San Miguel J, Blade J, Boccadoro M, et al. A practical update on the use of bortezomib in the management of multiple myeloma. Oncologist 2006; 11: 51-61
    • (2006) Oncologist , vol.11 , pp. 51-61
    • San Miguel, J.1    Blade, J.2    Boccadoro, M.3
  • 134
    • 34548010511 scopus 로고    scopus 로고
    • Analysis of varicella zoster virus reactivation among bortezomib-treated patients in the APEX study [abstract]
    • Chanan-Khan AA, Sonneveld P, Schuster WM, et al. Analysis of varicella zoster virus reactivation among bortezomib-treated patients in the APEX study [abstract]. Blood 2006; 108: 3535a
    • (2006) Blood , vol.108
    • Chanan-Khan, A.A.1    Sonneveld, P.2    Schuster, W.M.3
  • 135
    • 34147216614 scopus 로고    scopus 로고
    • Bortezomib when given pretransplant and once weekly as consolidation therapy following high dose chemotherapy leads to high rates of reactivation of varicella zoster virus [abstract]
    • Peles S, Fisher NM, Devien SM, et al. Bortezomib when given pretransplant and once weekly as consolidation therapy following high dose chemotherapy leads to high rates of reactivation of varicella zoster virus [abstract]. Blood 2005; 106: 3237a
    • (2005) Blood , vol.106
    • Peles, S.1    Fisher, N.M.2    Devien, S.M.3
  • 136
    • 33746700799 scopus 로고    scopus 로고
    • Tumour lysis syndrome early after treatment with bortezomib for multiple myeloma
    • Kenealy KM, Prince HM, Honemann D. Tumour lysis syndrome early after treatment with bortezomib for multiple myeloma. Pharmacotherapy 2006; 26: 1205-6
    • (2006) Pharmacotherapy , vol.26 , pp. 1205-1206
    • Kenealy, K.M.1    Prince, H.M.2    Honemann, D.3
  • 137
    • 0037677338 scopus 로고    scopus 로고
    • An UK myeloma forum phase II study of thalidomide: Long term follow-up and recommendations for treatment
    • Schey SA, Cavenagh J, Johnson R, et al. An UK myeloma forum phase II study of thalidomide: long term follow-up and recommendations for treatment. Leuk Res 2003; 27: 909-14
    • (2003) Leuk Res , vol.27 , pp. 909-914
    • Schey, S.A.1    Cavenagh, J.2    Johnson, R.3
  • 138
    • 6844252283 scopus 로고    scopus 로고
    • Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events
    • Berenson J, Lichtenstein A, Porter L, et al. Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. J Clin Oncol 1998; 16: 593-602
    • (1998) J Clin Oncol , vol.16 , pp. 593-602
    • Berenson, J.1    Lichtenstein, A.2    Porter, L.3
  • 139
    • 0035463593 scopus 로고    scopus 로고
    • Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patient with breast cancer or osteolytic lesions of multiple myeloma: A phase II double-blind comparative trial
    • Rosen LS, Gordon D, Antonio BS, et al. Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patient with breast cancer or osteolytic lesions of multiple myeloma: a phase II double-blind comparative trial. Cancer J 2001; 7: 377-87
    • (2001) Cancer J , vol.7 , pp. 377-387
    • Rosen, L.S.1    Gordon, D.2    Antonio, B.S.3
  • 140
    • 0034937438 scopus 로고    scopus 로고
    • Long term follow-up of a prospective double blind placebo-controlled randomized trail of clodronate in multiple myeloma
    • McClosley EV, Dunn JA, Kanis JA, et al. Long term follow-up of a prospective double blind placebo-controlled randomized trail of clodronate in multiple myeloma. Br J Haematol 2001; 113: 1035-43
    • (2001) Br J Haematol , vol.113 , pp. 1035-1043
    • McClosley, E.V.1    Dunn, J.A.2    Kanis, J.A.3
  • 141
    • 0028202499 scopus 로고
    • Preclinical pharmacology of CGP 42'446, a new potent heterocyclic bisphosphonate compound
    • Green JR, Mulier K, Jaeggi KA. Preclinical pharmacology of CGP 42'446, a new potent heterocyclic bisphosphonate compound. J Bone Miner Res 1994; 9: 745-51
    • (1994) J Bone Miner Res , vol.9 , pp. 745-751
    • Green, J.R.1    Mulier, K.2    Jaeggi, K.A.3
  • 142
    • 10744233021 scopus 로고    scopus 로고
    • Long term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M, et al. Long term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer 2003; 98: 1735-44
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 143
    • 34347260332 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2007 clinical practice guideline update on the role of bisphosphonates in multiple myeloma
    • Kyle AR, Yee CG, Somerfield RM, et al. American Society of Clinical Oncology 2007 clinical practice guideline update on the role of bisphosphonates in multiple myeloma. J Clin Oncol 2007; 25: 2464-72
    • (2007) J Clin Oncol , vol.25 , pp. 2464-2472
    • Kyle, A.R.1    Yee, C.G.2    Somerfield, R.M.3
  • 144
    • 33644906138 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in multiple myeloma patients: Clinical features and risk factors
    • Badros A, Weikel D, Salama A, et al. Osteonecrosis of the jaw in multiple myeloma patients: clinical features and risk factors. J Clin Oncol 2006; 24 (6): 945-52
    • (2006) J Clin Oncol , vol.24 , Issue.6 , pp. 945-952
    • Badros, A.1    Weikel, D.2    Salama, A.3
  • 145
    • 20844438840 scopus 로고    scopus 로고
    • The Australian Cancer Anaemia Survey: A snapshot of anaemia in adult patients with cancer
    • Seshardri T, Prince M, Bell D, et al. The Australian Cancer Anaemia Survey: a snapshot of anaemia in adult patients with cancer. Med J Aus 2005; 182 (9): 453-7
    • (2005) Med J Aus , vol.182 , Issue.9 , pp. 453-457
    • Seshardri, T.1    Prince, M.2    Bell, D.3
  • 146
    • 33749237119 scopus 로고    scopus 로고
    • Evaluation of anaemia in patients with multiple myeloma and lymphoma: Findings of the European CANCER ANAEMIA SURVEY
    • Birgegard G, Gascon P, Ludwig H. Evaluation of anaemia in patients with multiple myeloma and lymphoma: findings of the European CANCER ANAEMIA SURVEY. Eur J Haematol 2006; 77: 378-86
    • (2006) Eur J Haematol , vol.77 , pp. 378-386
    • Birgegard, G.1    Gascon, P.2    Ludwig, H.3
  • 147
    • 0035021209 scopus 로고    scopus 로고
    • Efficacy of epoetin alfa in myelothe treatment of anaemia of multiple myeloma
    • Dammaccos F, Castoldi G, Rodjer S. Efficacy of epoetin alfa in myelothe treatment of anaemia of multiple myeloma. Br J Haematol 2001; 113: 172-9
    • (2001) Br J Haematol , vol.113 , pp. 172-179
    • Dammaccos, F.1    Castoldi, G.2    Rodjer, S.3
  • 148
    • 0041627742 scopus 로고    scopus 로고
    • Efficacy and safety of darbepoetin alfa in anaemic patients with lymphoproliferative malignancies: A randomized, double blind, placebo controlled study
    • Hedenus M, Adriansson M, San Miguel J, et al. Efficacy and safety of darbepoetin alfa in anaemic patients with lymphoproliferative malignancies: a randomized, double blind, placebo controlled study. Br J Haematol 2003; 122: 394-403
    • (2003) Br J Haematol , vol.122 , pp. 394-403
    • Hedenus, M.1    Adriansson, M.2    San Miguel, J.3
  • 149
    • 0028793205 scopus 로고
    • Recombinant human erythropoietin in the anemia associated with multiple myeloma or non-Hodgkin's lymphoma: Dose finding and identification of predictors of response
    • Cazzola M, Messinger D, Battistell V, et al. Recombinant human erythropoietin in the anemia associated with multiple myeloma or non-Hodgkin's lymphoma: dose finding and identification of predictors of response. Blood 1995; 86: 4446-53
    • (1995) Blood , vol.86 , pp. 4446-4453
    • Cazzola, M.1    Messinger, D.2    Battistell, V.3
  • 150
    • 35148840952 scopus 로고    scopus 로고
    • Bortezomib in combination with high-dose dexamethasone (HD dex) and erythropoietin (EPO) does not result in an increased risk of thromboembolic complications [abstract]
    • Harousseau JL, Jagannath S, Richardson P, et al. Bortezomib in combination with high-dose dexamethasone (HD dex) and erythropoietin (EPO) does not result in an increased risk of thromboembolic complications [abstract]. Blood 2006; 108: 3543a
    • (2006) Blood , vol.108
    • Harousseau, J.L.1    Jagannath, S.2    Richardson, P.3
  • 151
    • 0036787775 scopus 로고    scopus 로고
    • Use of epoetin in patients with cancer: Evidence based clinical practice guidelines of the American Society of Clinical Oncology and American Society of Hematology
    • Rizzo JD, Lichtin AE, Woolf SH, et al. Use of epoetin in patients with cancer: evidence based clinical practice guidelines of the American Society of Clinical Oncology and American Society of Hematology. J Clin Oncol 2002; 20: 4083-107
    • (2002) J Clin Oncol , vol.20 , pp. 4083-4107
    • Rizzo, J.D.1    Lichtin, A.E.2    Woolf, S.H.3
  • 152
    • 0142186283 scopus 로고    scopus 로고
    • Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial
    • Henke M, Laszig R, Rube C, et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet 2003; 362: 1255-60
    • (2003) Lancet , vol.362 , pp. 1255-1260
    • Henke, M.1    Laszig, R.2    Rube, C.3
  • 153
    • 24944454286 scopus 로고    scopus 로고
    • Maintaining normal hemoglobin levels with epoietin alfa in mainly nonanaemic patients with metastatic breast cancer receiving first-line chemotherapy: A survival study
    • Leyland-Jones B, Siemiglazov V, Pawlicki M, et al. Maintaining normal hemoglobin levels with epoietin alfa in mainly nonanaemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study. J Clin Oncol 2005; 23: 5960-72
    • (2005) J Clin Oncol , vol.23 , pp. 5960-5972
    • Leyland-Jones, B.1    Siemiglazov, V.2    Pawlicki, M.3
  • 154
    • 34250349152 scopus 로고    scopus 로고
    • Weighing the hazards of erythropoiesis stimulation in patients with cancer
    • Khuri RF. Weighing the hazards of erythropoiesis stimulation in patients with cancer. N Engl J Med 2007; 356: 2445-8
    • (2007) N Engl J Med , vol.356 , pp. 2445-2448
    • Khuri, R.F.1
  • 155
    • 34250310054 scopus 로고    scopus 로고
    • Do cancer cells express functional erythropoietic receptors?
    • Longmore DG. Do cancer cells express functional erythropoietic receptors? N Engl J Med 2007; 356: 2447
    • (2007) N Engl J Med , vol.356 , pp. 2447
    • Longmore, D.G.1
  • 156
    • 14844314783 scopus 로고    scopus 로고
    • Evolving treatment strategies for myeloma
    • Morgan GI, Davies FE. Evolving treatment strategies for myeloma. Br J Cancer 2005; 92: 217-21
    • (2005) Br J Cancer , vol.92 , pp. 217-221
    • Morgan, G.I.1    Davies, F.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.