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Volumn 36, Issue 12, 2006, Pages 781-789

Current status of new drugs for the treatment of patients with multiple myeloma

Author keywords

Bortezomib; Lenalidomide; Multiple myeloma; Thalidomide; Treatment

Indexed keywords

ACETYLSALICYLIC ACID; ANTHRACYCLINE; BISPHOSPHONIC ACID DERIVATIVE; BORTEZOMIB; DEXAMETHASONE; ENOXAPARIN; LENALIDOMIDE; LOW MOLECULAR WEIGHT HEPARIN; MELPHALAN; THALIDOMIDE; VINCRISTINE; WARFARIN;

EID: 33750626750     PISSN: 14440903     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.2006.01218.x     Document Type: Review
Times cited : (13)

References (70)
  • 1
    • 22144472629 scopus 로고    scopus 로고
    • The adverse prognostic impact of advanced age in multiple myeloma
    • Mileshkin L, Prince HM. The adverse prognostic impact of advanced age in multiple myeloma. Leuk Lymphoma 2005; 46: 951-66.
    • (2005) Leuk Lymphoma , vol.46 , pp. 951-966
    • Mileshkin, L.1    Prince, H.M.2
  • 3
    • 8944220233 scopus 로고    scopus 로고
    • The Intergroupe Francais du Myelome, a prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
    • Attal M, Harousseau JL, Stoppa A, Sotto J, Fuzibet J, Rossi J et al. The Intergroupe Francais du Myelome, A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. N Engl J Med 1996; 335: 91-7.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.3    Sotto, J.4    Fuzibet, J.5    Rossi, J.6
  • 4
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Medical Research Council Adult Leukaemia Working Party
    • Child JA, Morgan GJ, Davies FE, Owen R, Bell S, Hawkins K et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. Medical Research Council Adult Leukaemia Working Party. N Engl J Med 2003; 348: 1875-83.
    • (2003) N Engl J Med , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3    Owen, R.4    Bell, S.5    Hawkins, K.6
  • 5
    • 0344076348 scopus 로고    scopus 로고
    • Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: An overview of 6,633 patients from 27 randomized trials
    • Myeloma Trialists' Collaborative Group
    • Myeloma Trialists' Collaborative Group. Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. J Clin Oncol 1998; 16: 3832-42.
    • (1998) J Clin Oncol , vol.16 , pp. 3832-3842
  • 6
    • 32644438680 scopus 로고    scopus 로고
    • Dexamethasone-based regimens versus melphalan-prednisone for elderly multiple myeloma patients ineligible for high-dose therapy
    • Intergroupe Francophone du Myélome (IFM) Group
    • Facon T, Mary JY, Pégourie B, Attal M, Renaud M, Sadoun A et al. Dexamethasone-based regimens versus melphalan-prednisone for elderly multiple myeloma patients ineligible for high-dose therapy. Intergroupe Francophone du Myélome (IFM) Group. Blood 2006; 107: 1292-8.
    • (2006) Blood , vol.107 , pp. 1292-1298
    • Facon, T.1    Mary, J.Y.2    Pégourie, B.3    Attal, M.4    Renaud, M.5    Sadoun, A.6
  • 7
    • 27744568383 scopus 로고    scopus 로고
    • Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma
    • Dewald G, Therneau T, Larson D, Lee YK, Fink S, Smoley S et al. Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma. Blood 2005; 106: 3553-8.
    • (2005) Blood , vol.106 , pp. 3553-3558
    • Dewald, G.1    Therneau, T.2    Larson, D.3    Lee, Y.K.4    Fink, S.5    Smoley, S.6
  • 8
    • 0036721371 scopus 로고    scopus 로고
    • Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy
    • Moreau P, Facon T, Leleu T, Morineau N, Huyghe P, Harousseau JL et al. Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy. Blood 2002; 100: 1579-83.
    • (2002) Blood , vol.100 , pp. 1579-1583
    • Moreau, P.1    Facon, T.2    Leleu, T.3    Morineau, N.4    Huyghe, P.5    Harousseau, J.L.6
  • 10
    • 0036884062 scopus 로고    scopus 로고
    • Molecular mechanisms of novel therapeutic approaches for multiple myeloma
    • Hideshima T, Anderson K. Molecular mechanisms of novel therapeutic approaches for multiple myeloma. Nat Rev Cancer 2002; 2: 927-37.
    • (2002) Nat Rev Cancer , vol.2 , pp. 927-937
    • Hideshima, T.1    Anderson, K.2
  • 11
    • 0034331194 scopus 로고    scopus 로고
    • Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
    • Hideshima T, Chauhan D, Shima Y, Raje N, Davies F, Tai Y-T et al. Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy. Blood 2000; 96: 2943-50.
    • (2000) Blood , vol.96 , pp. 2943-2950
    • Hideshima, T.1    Chauhan, D.2    Shima, Y.3    Raje, N.4    Davies, F.5    Tai, Y.-T.6
  • 12
    • 28844472902 scopus 로고    scopus 로고
    • Lenalidomide and thalidomide: Mechanisms of action - Similarities and differences
    • Anderson K. Lenalidomide and thalidomide: mechanisms of action - similarities and differences. Semin Hematol 2005; 42: S3-S8.
    • (2005) Semin Hematol , vol.42
    • Anderson, K.1
  • 14
    • 0038305911 scopus 로고    scopus 로고
    • A multi-centre phase II trial of thalidomide in relapsed/refractory multiple myeloma reveals an adverse prognostic impact of advanced age
    • Mileshkin L, Biagi J, Mitchell P, Underhill C, Grigg A, Bell R et al. A multi-centre phase II trial of thalidomide in relapsed/refractory multiple myeloma reveals an adverse prognostic impact of advanced age. Blood 2003; 102: 69-77.
    • (2003) Blood , vol.102 , pp. 69-77
    • Mileshkin, L.1    Biagi, J.2    Mitchell, P.3    Underhill, C.4    Grigg, A.5    Bell, R.6
  • 15
    • 0036380265 scopus 로고    scopus 로고
    • Thalidomide in patients with advanced multiple myeloma: A study of 83 patients - Report of the Intergroupe Francophone due Myeloma (IFM)
    • Yakoub-Agha I, Attal M, Dumontet C, Delannoy V, Moreau P, Berthou C et al. Thalidomide in patients with advanced multiple myeloma: a study of 83 patients - report of the Intergroupe Francophone due Myeloma (IFM). Hematol J 2002; 3: 185-92.
    • (2002) Hematol J , vol.3 , pp. 185-192
    • Yakoub-Agha, I.1    Attal, M.2    Dumontet, C.3    Delannoy, V.4    Moreau, P.5    Berthou, C.6
  • 16
    • 0036846653 scopus 로고    scopus 로고
    • Dose-dependent effect of thalidomide on overall survival in relapsed multiple myeloma
    • Neben K, Moehler T, Benner A, Kraemer A, Egerer G, Ho A et al. Dose-dependent effect of thalidomide on overall survival in relapsed multiple myeloma. Clin Cancer Res 2002; 8: 3377-82.
    • (2002) Clin Cancer Res , vol.8 , pp. 3377-3382
    • Neben, K.1    Moehler, T.2    Benner, A.3    Kraemer, A.4    Egerer, G.5    Ho, A.6
  • 17
    • 33644898842 scopus 로고    scopus 로고
    • A systematic review of phase-II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma
    • Glasmacher A, Hahn C, Hoffmann F. A systematic review of phase-II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma. Br J Haematol 2006; 132: 584-93.
    • (2006) Br J Haematol , vol.132 , pp. 584-593
    • Glasmacher, A.1    Hahn, C.2    Hoffmann, F.3
  • 18
    • 33749011624 scopus 로고    scopus 로고
    • Efficacy of single-agent bortezomib versus thalidomide in patients with relapsed or refractory multiple myeloma: A systematic review
    • [abstract]
    • Prince HM, Adena M, Smith DK, Hertel J. Efficacy of single-agent bortezomib versus thalidomide in patients with relapsed or refractory multiple myeloma: a systematic review [abstract]. Blood 2005; 106: 5160.
    • (2005) Blood , vol.106 , pp. 5160
    • Prince, H.M.1    Adena, M.2    Smith, D.K.3    Hertel, J.4
  • 19
    • 4544386351 scopus 로고    scopus 로고
    • Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma
    • Palumbo A, Bertola A, Falco P, Rosato R, Cavallo F, Giaccone L et al. Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma. Hematol J 2004; 5: 318-24.
    • (2004) Hematol J , vol.5 , pp. 318-324
    • Palumbo, A.1    Bertola, A.2    Falco, P.3    Rosato, R.4    Cavallo, F.5    Giaccone, L.6
  • 21
    • 4544386351 scopus 로고    scopus 로고
    • Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma
    • Palumbo A, Bertola A, Falco P, Rosato R, Cavallo F, Giaccone L et al. Efficacy of low-dose thalidomide and dexamethasone as first salvage regimen in multiple myeloma. Hematol J 2004; 5: 318-24.
    • (2004) Hematol J , vol.5 , pp. 318-324
    • Palumbo, A.1    Bertola, A.2    Falco, P.3    Rosato, R.4    Cavallo, F.5    Giaccone, L.6
  • 23
    • 0041629471 scopus 로고    scopus 로고
    • DTPACE: An effective, novel combination chemotherapy with thalidomide for previously treated patients with myeloma
    • Lee CK, Barlogie B, Munshi N, Zangari M, Fassas A, Jacobson J et al. DTPACE: an effective, novel combination chemotherapy with thalidomide for previously treated patients with myeloma. J Clin Oncol 2003; 21: 2732-9.
    • (2003) J Clin Oncol , vol.21 , pp. 2732-2739
    • Lee, C.K.1    Barlogie, B.2    Munshi, N.3    Zangari, M.4    Fassas, A.5    Jacobson, J.6
  • 25
    • 0035895104 scopus 로고    scopus 로고
    • Salvage therapy for multiple myeloma with thalidomide and CED chemotherapy
    • Moehler TM, Neben K, Benner A, Egerer G, Krasniqi F, Ho A et al. Salvage therapy for multiple myeloma with thalidomide and CED chemotherapy. Blood 2001; 98: 3846-8.
    • (2001) Blood , vol.98 , pp. 3846-3848
    • Moehler, T.M.1    Neben, K.2    Benner, A.3    Egerer, G.4    Krasniqi, F.5    Ho, A.6
  • 26
    • 11144356289 scopus 로고    scopus 로고
    • Pulsed cyclophosphamide, thalidomide and dexamethasone: An oral regimen for previously treated patients with multiple myeloma
    • Dimopoulos MA, Hamilos G, Zomas A, Gika D, Efstathiou E, Grigoraki V et al. Pulsed cyclophosphamide, thalidomide and dexamethasone: an oral regimen for previously treated patients with multiple myeloma. Hematol J 2004; 5: 112-17.
    • (2004) Hematol J , vol.5 , pp. 112-117
    • Dimopoulos, M.A.1    Hamilos, G.2    Zomas, A.3    Gika, D.4    Efstathiou, E.5    Grigoraki, V.6
  • 27
    • 1942522741 scopus 로고    scopus 로고
    • The oral combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is effective in relapsed/refractory multiple myeloma
    • García-Sanz R, González-Porras J, Hernández J, Polo-Zarzuela M, Sureda A, Barrenetxea C et al. The oral combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is effective in relapsed/refractory multiple myeloma. Leukemia 2004; 18: 856-63.
    • (2004) Leukemia , vol.18 , pp. 856-863
    • García-Sanz, R.1    González-Porras, J.2    Hernández, J.3    Polo-Zarzuela, M.4    Sureda, A.5    Barrenetxea, C.6
  • 28
    • 33745628076 scopus 로고    scopus 로고
    • Phase 2 study of pegylated liposomal doxorubicin, vincristine, decreased-frequency dexamethasone, and thalidomide in newly diagnosed and relapsed-refractory multiple myeloma
    • Hussein MA, Baz R, Srkalovic G, Agrawal N, Suppiah R, Hsi E et al. Phase 2 study of pegylated liposomal doxorubicin, vincristine, decreased-frequency dexamethasone, and thalidomide in newly diagnosed and relapsed-refractory multiple myeloma. Mayo Clin Proc 2006; 81: 889-95.
    • (2006) Mayo Clin Proc , vol.81 , pp. 889-895
    • Hussein, M.A.1    Baz, R.2    Srkalovic, G.3    Agrawal, N.4    Suppiah, R.5    Hsi, E.6
  • 29
    • 0037208595 scopus 로고    scopus 로고
    • Thalidomide alone or with dexamethasone for previously untreated multiple myeloma
    • Weber D, Rankin K, Gavino M, Delasalle K, Alexanian R. Thalidomide alone or with dexamethasone for previously untreated multiple myeloma. J Clin Oncol 2003; 21: 16-19.
    • (2003) J Clin Oncol , vol.21 , pp. 16-19
    • Weber, D.1    Rankin, K.2    Gavino, M.3    Delasalle, K.4    Alexanian, R.5
  • 30
    • 3242760702 scopus 로고    scopus 로고
    • First-line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma
    • Cavo M, Zamagni E, Tosi P, Cellini C, Cangini D, Tacchetti P et al. First-line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma. Haematologica 2004; 89: 826-31.
    • (2004) Haematologica , vol.89 , pp. 826-831
    • Cavo, M.1    Zamagni, E.2    Tosi, P.3    Cellini, C.4    Cangini, D.5    Tacchetti, P.6
  • 31
    • 0036843032 scopus 로고    scopus 로고
    • Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma
    • Rajkumar S, Hayman S, Gertz M, Dispenzieri A, Lacy M, Greipp P et al. Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma. J Clin Oncol 2002; 20: 4319-23.
    • (2002) J Clin Oncol , vol.20 , pp. 4319-4323
    • Rajkumar, S.1    Hayman, S.2    Gertz, M.3    Dispenzieri, A.4    Lacy, M.5    Greipp, P.6
  • 32
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • Rajkumar S, Blood E, Vesole D, Fonseca R, Greipp P. Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol 2006; 24: 431-6.
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.1    Blood, E.2    Vesole, D.3    Fonseca, R.4    Greipp, P.5
  • 33
    • 22044452126 scopus 로고    scopus 로고
    • Superiority of thalidomide and dexamethasone over vincristine- doxorubicin-dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma
    • Cavo M, Zamagni E, Tosi P, Tacchetti P, Cellini C, Cangini D et al. Superiority of thalidomide and dexamethasone over vincristine-doxorubicin- dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood 2005; 106: 35-9.
    • (2005) Blood , vol.106 , pp. 35-39
    • Cavo, M.1    Zamagni, E.2    Tosi, P.3    Tacchetti, P.4    Cellini, C.5    Cangini, D.6
  • 34
    • 33644837094 scopus 로고    scopus 로고
    • Thalidomide and dexamethasone: A new standard of care for initial therapy in multiple myeloma
    • [editorial]
    • Richardson P, Anderson K. Thalidomide and dexamethasone: a new standard of care for initial therapy in multiple myeloma [editorial]. J Clin Oncol 2006; 24: 334-6.
    • (2006) J Clin Oncol , vol.24 , pp. 334-336
    • Richardson, P.1    Anderson, K.2
  • 36
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomized controlled trial
    • Palumbo A, Bringhen S, Caravita T, Merla E, Capparella V, Callea V et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomized controlled trial. Lancet 2006; 367: 825-31.
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3    Merla, E.4    Capparella, V.5    Callea, V.6
  • 37
    • 19944426090 scopus 로고    scopus 로고
    • Results of amulticenter randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant
    • Stewart AK, Chen CI, Howson-Jan K, White D, Roy J, Kovacs M et al. Results of amulticenter randomized phase II trial of thalidomide and prednisone maintenance therapy for multiple myeloma after autologous stem cell transplant. Clin Cancer Res 2004; 10: 8170-76.
    • (2004) Clin Cancer Res , vol.10 , pp. 8170-8176
    • Stewart, A.K.1    Chen, C.I.2    Howson-Jan, K.3    White, D.4    Roy, J.5    Kovacs, M.6
  • 38
    • 0035990841 scopus 로고    scopus 로고
    • Consolidation therapy of multiple myeloma with thalidomide-dexamethasone after intensive chemotherapy
    • Alexanian R, Weber D, Giralt S, Delasalle K. Consolidation therapy of multiple myeloma with thalidomide-dexamethasone after intensive chemotherapy. Ann Oncol 2002; 13: 1116-19.
    • (2002) Ann Oncol , vol.13 , pp. 1116-1119
    • Alexanian, R.1    Weber, D.2    Giralt, S.3    Delasalle, K.4
  • 39
    • 33751164196 scopus 로고    scopus 로고
    • Maintenance therapy with thalidomide improves survival in multiple myeloma patients
    • First Edition Paper, prepublished online July 27, 2006
    • Attal M, Harousseau JL, Leyvraz S, Doyen C, Huylin C, Benboubker L et al. Maintenance therapy with thalidomide improves survival in multiple myeloma patients. Blood 2006; First Edition Paper, prepublished online July 27, 2006.
    • (2006) Blood
    • Attal, M.1    Harousseau, J.L.2    Leyvraz, S.3    Doyen, C.4    Huylin, C.5    Benboubker, L.6
  • 40
    • 33749051832 scopus 로고    scopus 로고
    • The development of neuropathy in patients with myeloma treated with thalidomide - Patterns of occurrence and the role of electrophysiologic monitoring
    • (in press)
    • Mileshkin L, Stark R, Day B, Seymour J, Zeldis J, Prince HM. The development of neuropathy in patients with myeloma treated with thalidomide - patterns of occurrence and the role of electrophysiologic monitoring. J Clin Oncol 2006 (in press).
    • (2006) J Clin Oncol
    • Mileshkin, L.1    Stark, R.2    Day, B.3    Seymour, J.4    Zeldis, J.5    Prince, H.M.6
  • 42
    • 0037103292 scopus 로고    scopus 로고
    • Thrombogenic activity of doxorubicin in myeloma patients receiving thalidomide: Implications for therapy
    • Zangari M, Siegel E, Barlogie B, Anaissie E, Saghafifar F, Fassas A et al. Thrombogenic activity of doxorubicin in myeloma patients receiving thalidomide: implications for therapy. Blood 2002; 100: 1168-71.
    • (2002) Blood , vol.100 , pp. 1168-1171
    • Zangari, M.1    Siegel, E.2    Barlogie, B.3    Anaissie, E.4    Saghafifar, F.5    Fassas, A.6
  • 43
    • 4544332965 scopus 로고    scopus 로고
    • Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: Effects of prophylactic and therapeutic anticoagulation
    • Zangari M, Barlogie B, Anaissie E, Saghafifar F, Eddlemon P, Jacobson J et al. Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation. Br J Haematol 2004; 126: 715-21.
    • (2004) Br J Haematol , vol.126 , pp. 715-721
    • Zangari, M.1    Barlogie, B.2    Anaissie, E.3    Saghafifar, F.4    Eddlemon, P.5    Jacobson, J.6
  • 44
    • 28544436819 scopus 로고    scopus 로고
    • Aspirin decreases the thrombotic complications induced by thalidomide when combined with anthracycline based chemotherapy regimens for the treatment of multiple myeloma
    • Baz R, Li L, Kottke-Marchant K, Srkalovic G, McGowan B, Yannaki E et al. Aspirin decreases the thrombotic complications induced by thalidomide when combined with anthracycline based chemotherapy regimens for the treatment of multiple myeloma. Mayo Clin Proc 2005; 80: 1568-74.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1568-1574
    • Baz, R.1    Li, L.2    Kottke-Marchant, K.3    Srkalovic, G.4    McGowan, B.5    Yannaki, E.6
  • 45
    • 28544451098 scopus 로고    scopus 로고
    • Thalidomide therapy and deep venous thrombosis in multiple myeloma
    • [editorial]
    • Rajkumar S. Thalidomide therapy and deep venous thrombosis in multiple myeloma [editorial]. Mayo Clin Proc 2005; 80: 1549-51.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1549-1551
    • Rajkumar, S.1
  • 46
    • 28844472902 scopus 로고    scopus 로고
    • Lenalidomide and thalidomide: Mechanisms of action-similarities and differences
    • Anderson K. Lenalidomide and thalidomide: mechanisms of action-similarities and differences. Semin Hematol 2005; 42: S3-S8.
    • (2005) Semin Hematol , vol.42
    • Anderson, K.1
  • 47
    • 0032922147 scopus 로고    scopus 로고
    • S.T.E.P.S.: A comprehensive program for controlling and monitoring access to thalidomide
    • Zeldis J, Williams B, Thomas S, Elsayed M. S.T.E.P.S.: a comprehensive program for controlling and monitoring access to thalidomide. Clin Ther 1999; 21: 319-30.
    • (1999) Clin Ther , vol.21 , pp. 319-330
    • Zeldis, J.1    Williams, B.2    Thomas, S.3    Elsayed, M.4
  • 48
    • 33750607347 scopus 로고    scopus 로고
    • A Randomized Phase 2 Study of Lenalidomide Therapy for Patients with Relapsed or Relapsed and refractory Multiple Myeloma
    • First Edition Paper, prepublished online July 18, 2006
    • Richardson P, Blood E, Mitsiades C, Jagannath S, Zeldenrust S, Alsina M et al. A Randomized Phase 2 Study of Lenalidomide Therapy for Patients with Relapsed or Relapsed and refractory Multiple Myeloma. Blood 2006; First Edition Paper, prepublished online July 18, 2006.
    • (2006) Blood
    • Richardson, P.1    Blood, E.2    Mitsiades, C.3    Jagannath, S.4    Zeldenrust, S.5    Alsina, M.6
  • 49
    • 28844490092 scopus 로고    scopus 로고
    • Management of the relapsed/refractory myeloma patient: Strategies incorporating lenalidomide
    • Richardson P. Management of the relapsed/refractory myeloma patient: strategies incorporating lenalidomide. Semin Hematol 2005; 42: S9-S15.
    • (2005) Semin Hematol , vol.42
    • Richardson, P.1
  • 50
    • 33644816914 scopus 로고    scopus 로고
    • Study of lenalidomide plus dexamethasone versus dexamethasone alone in relapsed or refractory multiple myeloma (MM): Results of a phase 3 study (MM-010)
    • [abstract]
    • Dimopoulos M, Spencer A, Attal M et al. Study of lenalidomide plus dexamethasone versus dexamethasone alone in relapsed or refractory multiple myeloma (MM): results of a phase 3 study (MM-010) [abstract]. Blood 2005; 105: 6.
    • (2005) Blood , vol.105 , pp. 6
    • Dimopoulos, M.1    Spencer, A.2    Attal, M.3
  • 52
    • 33750614374 scopus 로고    scopus 로고
    • Lenalidomide (Revlimid) Achieves a High Response Rate in Patients with Relapsed or Refractory Multiple Myeloma: Local Analysis of the International MM010 & MM012 Studies
    • abstract 122
    • Kenealy M, Prince HM, Spencer A. Lenalidomide (Revlimid) Achieves a High Response Rate in Patients with Relapsed or Refractory Multiple Myeloma: Local Analysis of the International MM010 & MM012 Studies. Haematology Society of Australia and New Zealand Annual Scientific Meeting 2005; abstract 122.
    • (2005) Haematology Society of Australia and New Zealand Annual Scientific Meeting
    • Kenealy, M.1    Prince, H.M.2    Spencer, A.3
  • 53
    • 27744492561 scopus 로고    scopus 로고
    • Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma
    • Rajkumar S, Hayman S, Lacy M, Dispenzieri A, Geyer S, Kabat B et al. Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma. Blood 2005; 106: 4050-53.
    • (2005) Blood , vol.106 , pp. 4050-4053
    • Rajkumar, S.1    Hayman, S.2    Lacy, M.3    Dispenzieri, A.4    Geyer, S.5    Kabat, B.6
  • 54
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, Richardson P, Chauhan D, Palombella V, Elliott P, Adams J et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001; 61: 3071-6.
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3    Palombella, V.4    Elliott, P.5    Adams, J.6
  • 57
    • 33644844108 scopus 로고    scopus 로고
    • Extended follow-up of a phase II trial in relapsed, refractory multiple myeloma; final time-to-event results from the SUMMIT trial
    • Richardson P, Barlogie B, Berenson J, Singhal S, Jag S, Irwin D et al. Extended follow-up of a phase II trial in relapsed, refractory multiple myeloma; final time-to-event results from the SUMMIT trial. Cancer 2006; 106: 1316-19.
    • (2006) Cancer , vol.106 , pp. 1316-1319
    • Richardson, P.1    Barlogie, B.2    Berenson, J.3    Singhal, S.4    Jag, S.5    Irwin, D.6
  • 58
    • 33644885460 scopus 로고    scopus 로고
    • Descriptive and prognostic value of patient-reported outcomes: The bortezomib experience in relapsed and refractory multiple myeloma
    • Dubois D, Dhawan R, van de Velde H, Esseltine D, Gupta S, Viala M et al. Descriptive and prognostic value of patient-reported outcomes: the bortezomib experience in relapsed and refractory multiple myeloma. J Clin Oncol 2006; 24: 976-82.
    • (2006) J Clin Oncol , vol.24 , pp. 976-982
    • Dubois, D.1    Dhawan, R.2    Van De Velde, H.3    Esseltine, D.4    Gupta, S.5    Viala, M.6
  • 60
    • 21344469223 scopus 로고    scopus 로고
    • Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma
    • Jagannath S, Durie B, Wolf J, Camacho E, Irwin D, Lutzky J et al. Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma. Br J Haematol 2005; 129: 776-83.
    • (2005) Br J Haematol , vol.129 , pp. 776-783
    • Jagannath, S.1    Durie, B.2    Wolf, J.3    Camacho, E.4    Irwin, D.5    Lutzky, J.6
  • 61
    • 21344464281 scopus 로고    scopus 로고
    • Bortezomib (VELCADE®) plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: Preliminary results of an IFM phase II study
    • [abstract]
    • Harousseau JL, Attal M, Leleu X, Gressin R, Hulin C, Fuzibet J-G et al. Bortezomib (VELCADE®) plus dexamethasone as induction treatment prior to autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: preliminary results of an IFM phase II study [abstract]. Blood 2004; 104: 1490.
    • (2004) Blood , vol.104 , pp. 1490
    • Harousseau, J.L.1    Attal, M.2    Leleu, X.3    Gressin, R.4    Hulin, C.5    Fuzibet, J.-G.6
  • 62
    • 0037342894 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
    • Ma MH, Yang HH, Parker K, Manyak S, Friedman J, Altamirano C et al. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin Cancer Res 2003; 9: 1136-44.
    • (2003) Clin Cancer Res , vol.9 , pp. 1136-1144
    • Ma, M.H.1    Yang, H.H.2    Parker, K.3    Manyak, S.4    Friedman, J.5    Altamirano, C.6
  • 63
    • 33644916110 scopus 로고    scopus 로고
    • Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma
    • Berenson J, Yang H, Sadler K, Jarutirasarn S, Vescio R, Mapes R et al. Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma. J Clin Oncol 2006; 24: 937-44.
    • (2006) J Clin Oncol , vol.24 , pp. 937-944
    • Berenson, J.1    Yang, H.2    Sadler, K.3    Jarutirasarn, S.4    Vescio, R.5    Mapes, R.6
  • 65
    • 21344458719 scopus 로고    scopus 로고
    • VTD (Velcade, thalidomide, dexamethasone) as primary therapy for newly diagnosed multiple myeloma
    • [abstract]
    • Wang L, Weber D, Delasalle K, Alexanian R. VTD (Velcade, thalidomide, dexamethasone) as primary therapy for newly diagnosed multiple myeloma [abstract]. Blood 2004; 104: 210.
    • (2004) Blood , vol.104 , pp. 210
    • Wang, L.1    Weber, D.2    Delasalle, K.3    Alexanian, R.4
  • 66
    • 23944475760 scopus 로고    scopus 로고
    • Marked activity of Velcade plus thalidomide (V+T) in advanced and refractory multiple myeloma (MM)
    • [abstract]
    • Zangari M, Barlogie B, Hollmig K, Fassas A, Rasmussen E, Thertulien R et al. Marked activity of Velcade plus thalidomide (V+T) in advanced and refractory multiple myeloma (MM) [abstract]. Blood 2004; 104: 1480.
    • (2004) Blood , vol.104 , pp. 1480
    • Zangari, M.1    Barlogie, B.2    Hollmig, K.3    Fassas, A.4    Rasmussen, E.5    Thertulien, R.6
  • 67
    • 33746700799 scopus 로고    scopus 로고
    • Tumour lysis syndrome early after treatment with bortezomib in multiple myeloma
    • Kenealy M, Prince M, Honemann D. Tumour lysis syndrome early after treatment with bortezomib in multiple myeloma. Pharmacotherapy 2006; 26: 1205-6.
    • (2006) Pharmacotherapy , vol.26 , pp. 1205-1206
    • Kenealy, M.1    Prince, M.2    Honemann, D.3
  • 68
    • 5644266386 scopus 로고    scopus 로고
    • Tumour lysis syndrome in multiple myeloma after bortezomib (VELCADE) administration
    • Terpos E, Politou M, Rahemtulla A. Tumour lysis syndrome in multiple myeloma after bortezomib (VELCADE) administration. J Cancer Res Clin Oncol 2004; 130: 623-5.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 623-625
    • Terpos, E.1    Politou, M.2    Rahemtulla, A.3
  • 69
    • 0346219279 scopus 로고    scopus 로고
    • New insights into the pathophysiology and management of bone disease in multiple myeloma
    • Terpos E, Politou M, Rahemtulla A. New insights into the pathophysiology and management of bone disease in multiple myeloma. Br J Haematol 2003; 123: 758-69.
    • (2003) Br J Haematol , vol.123 , pp. 758-769
    • Terpos, E.1    Politou, M.2    Rahemtulla, A.3
  • 70
    • 33750615614 scopus 로고    scopus 로고
    • [homepage on the Internet] Janssen-Pharmaceutica NV [updated 2 August 2005]. Available from
    • Velcade. info [homepage on the Internet]. Potential consequences of proteasome inhibition-NFκB. Janssen-Pharmaceutica NV [updated 2 August 2005]. Available from: http://www.velcade.info
    • Potential Consequences of Proteasome Inhibition-NFκB


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.