-
1
-
-
14944354884
-
Sydney Multicenter Study of Parkinson's disease: Non-L-dopa-responsive problems dominate at 15 years
-
Hely MA, Morris JG, Reid WG, et al. Sydney Multicenter Study of Parkinson's disease: Non-L-dopa-responsive problems dominate at 15 years. Mov Disord 2005;20:190-99
-
(2005)
Mov Disord
, vol.20
, pp. 190-199
-
-
Hely, M.A.1
Morris, J.G.2
Reid, W.G.3
-
2
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson TM, Dawson VL. Molecular pathways of neurodegeneration in Parkinson's disease. Science 2003;302:819-22
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
3
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 1997;276:2045-47
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
4
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392:605-8
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
-
5
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy E, Boyer R, Auburger G, et al. The ubiquitin pathway in Parkinson's disease. Nature 1998;395:451-52
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
-
6
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, Rizzu P, van Baren MJ, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003;299:256-59
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
van Baren, M.J.3
-
7
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004;304:1158-60
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
-
8
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
Zimprich A, Biskup S, Leitner P, et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004;44:601-7
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
-
9
-
-
24644431901
-
LRRK2 gene in Parkinson disease: Mutation analysis and case control association study
-
Paisan-Ruiz C, Lang AE, Kawarai T, et al. LRRK2 gene in Parkinson disease: Mutation analysis and case control association study. Neurology 2005;65:696-700
-
(2005)
Neurology
, vol.65
, pp. 696-700
-
-
Paisan-Ruiz, C.1
Lang, A.E.2
Kawarai, T.3
-
10
-
-
0036830525
-
A susceptibility gene for late-onset idiopathic Parkinson's disease
-
Hicks AA, Petursson H, Jonsson T, et al. A susceptibility gene for late-onset idiopathic Parkinson's disease. Ann Neurol 2002;52:549-55
-
(2002)
Ann Neurol
, vol.52
, pp. 549-555
-
-
Hicks, A.A.1
Petursson, H.2
Jonsson, T.3
-
11
-
-
18344393780
-
Age at onset in two common neurodegenerative diseases is genetically controlled
-
Li YJ, Scott WK, Hedges DJ, et al. Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet 2002;70:985-93
-
(2002)
Am J Hum Genet
, vol.70
, pp. 985-993
-
-
Li, Y.J.1
Scott, W.K.2
Hedges, D.J.3
-
12
-
-
22544472702
-
Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease
-
Oliveira SA, Li YJ, Noureddine MA, et al. Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. Am J Hum Genet 2005;77:252-64
-
(2005)
Am J Hum Genet
, vol.77
, pp. 252-264
-
-
Oliveira, S.A.1
Li, Y.J.2
Noureddine, M.A.3
-
13
-
-
27244451809
-
High-resolution whole-genome association study of Parkinson disease
-
Maraganore DM, de Andrade M, Lesnick TG, et al. High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet 2005;77:685-93
-
(2005)
Am J Hum Genet
, vol.77
, pp. 685-693
-
-
Maraganore, D.M.1
de Andrade, M.2
Lesnick, T.G.3
-
14
-
-
22544469751
-
Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra
-
Noureddine MA, Li YJ, van der Walt JM, et al. Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. Mov Disord 2005;20:1299-1309
-
(2005)
Mov Disord
, vol.20
, pp. 1299-1309
-
-
Noureddine, M.A.1
Li, Y.J.2
van der Walt, J.M.3
-
15
-
-
0032760196
-
Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein
-
Seki N, Hattori A, Hayashi A, et al. Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein. Biochim Biophys Acta 1999;1489:421-27
-
(1999)
Biochim Biophys Acta
, vol.1489
, pp. 421-427
-
-
Seki, N.1
Hattori, A.2
Hayashi, A.3
-
17
-
-
0034266806
-
RING finger proteins: Mediators of ubiquitin ligase activity
-
Joazeiro CA, Weissman AM. RING finger proteins: Mediators of ubiquitin ligase activity. Cell 2000;102:549-52
-
(2000)
Cell
, vol.102
, pp. 549-552
-
-
Joazeiro, C.A.1
Weissman, A.M.2
-
18
-
-
7044238416
-
Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
-
Forman MS, Trojanowski JQ, Lee VM. Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 2004;10:1055-63
-
(2004)
Nat Med
, vol.10
, pp. 1055-1063
-
-
Forman, M.S.1
Trojanowski, J.Q.2
Lee, V.M.3
-
19
-
-
0025908356
-
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
-
Mirra SS, Heyman A, McKeel D, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-86
-
(1991)
Neurology
, vol.41
, pp. 479-486
-
-
Mirra, S.S.1
Heyman, A.2
McKeel, D.3
-
21
-
-
0036522982
-
Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice
-
Zhang W, Basile AS, Gomeza J, et al. Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice. J Neurosci 2002;22:1709-17
-
(2002)
J Neurosci
, vol.22
, pp. 1709-1717
-
-
Zhang, W.1
Basile, A.S.2
Gomeza, J.3
-
22
-
-
0036322266
-
Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
-
Duda JE, Giasson BI, Mabon ME, et al. Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases. Ann Neurol 2002;52:205-10
-
(2002)
Ann Neurol
, vol.52
, pp. 205-210
-
-
Duda, J.E.1
Giasson, B.I.2
Mabon, M.E.3
-
23
-
-
0028936065
-
The dopamine transporter: Immunochemical characterization and localization in brain
-
Ciliax BJ, Heilman C, Demchyshyn LL, et al. The dopamine transporter: Immunochemical characterization and localization in brain. J Neurosci 1995;15:1714-23
-
(1995)
J Neurosci
, vol.15
, pp. 1714-1723
-
-
Ciliax, B.J.1
Heilman, C.2
Demchyshyn, L.L.3
-
24
-
-
0020692977
-
Monoclonal antibodies to choline acetyltransferase: Production, specificity, and immunohistochemistry
-
Levey AI, Armstrong DM, Atweh SF, et al. Monoclonal antibodies to choline acetyltransferase: Production, specificity, and immunohistochemistry. J Neurosci 1983;3:1-9
-
(1983)
J Neurosci
, vol.3
, pp. 1-9
-
-
Levey, A.I.1
Armstrong, D.M.2
Atweh, S.F.3
-
26
-
-
0033030440
-
Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease
-
Miller GW, Erickson JD, Perez JT, et al. Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Exp Neurol 1999;156:138-48
-
(1999)
Exp Neurol
, vol.156
, pp. 138-148
-
-
Miller, G.W.1
Erickson, J.D.2
Perez, J.T.3
-
27
-
-
0027465882
-
Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain
-
Levey AI. Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain. Life Sci 1993;52:441-48
-
(1993)
Life Sci
, vol.52
, pp. 441-448
-
-
Levey, A.I.1
-
28
-
-
0033933871
-
5 receptor immunolocalization in rat and monkey brain
-
5 receptor immunolocalization in rat and monkey brain. Synapse 2000;37:125-45
-
(2000)
Synapse
, vol.37
, pp. 125-145
-
-
Ciliax, B.J.1
Nash, N.2
Heilman, C.3
-
29
-
-
0033961490
-
Expression of α-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease
-
Solano SM, Miller DW, Augood SJ, et al. Expression of α-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease. Ann Neurol 2000;47:201-10
-
(2000)
Ann Neurol
, vol.47
, pp. 201-210
-
-
Solano, S.M.1
Miller, D.W.2
Augood, S.J.3
-
30
-
-
0031944830
-
Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity
-
Irizarry MC, Growdon W, Gomez-Isla T, et al. Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity. J Neuropathol Exp Neurol 1998;57:334-37
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 334-337
-
-
Irizarry, M.C.1
Growdon, W.2
Gomez-Isla, T.3
-
31
-
-
0020630852
-
Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis
-
Doran JF, Jackson P, Kynoch PA, et al. Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis. J Neurochem 1983;40:1542-47
-
(1983)
J Neurochem
, vol.40
, pp. 1542-1547
-
-
Doran, J.F.1
Jackson, P.2
Kynoch, P.A.3
-
32
-
-
10744224738
-
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
-
Bandopadhyay R, Kingsbury AE, Cookson MR, et al. The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. Brain 2004;127:420-30
-
(2004)
Brain
, vol.127
, pp. 420-430
-
-
Bandopadhyay, R.1
Kingsbury, A.E.2
Cookson, M.R.3
-
33
-
-
13844253723
-
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1
-
Goldberg MS, Pisani A, Haburcak M, et al. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron 2005;45:489-96
-
(2005)
Neuron
, vol.45
, pp. 489-496
-
-
Goldberg, M.S.1
Pisani, A.2
Haburcak, M.3
-
34
-
-
0037431172
-
Parkin: A multipurpose neuroprotective agent?
-
Feany MB, Pallanck LJ. Parkin: A multipurpose neuroprotective agent? Neuron 2003;38:13-16
-
(2003)
Neuron
, vol.38
, pp. 13-16
-
-
Feany, M.B.1
Pallanck, L.J.2
-
35
-
-
0035664746
-
α-Synuclein and cytosolic dopamine: Stabilizing a bad situation
-
Sulzer D. α-Synuclein and cytosolic dopamine: Stabilizing a bad situation. Nat Med 2001;7:1280-82
-
(2001)
Nat Med
, vol.7
, pp. 1280-1282
-
-
Sulzer, D.1
-
36
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R, Sherer TB, MacKenzie G, et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000;3:1301-6
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
-
37
-
-
0037036904
-
Proteasome inhibition causes nigral degeneration with inclusion bodies in rats
-
McNaught KS, Bjorklund LM, Belizaire R, et al. Proteasome inhibition causes nigral degeneration with inclusion bodies in rats. Neuroreport 2002;13:1437-41
-
(2002)
Neuroreport
, vol.13
, pp. 1437-1441
-
-
McNaught, K.S.1
Bjorklund, L.M.2
Belizaire, R.3
-
38
-
-
3042794162
-
Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease
-
McNaught KS, Perl DP, Brownell AL, et al. Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Ann Neurol 2004;56:149-62
-
(2004)
Ann Neurol
, vol.56
, pp. 149-162
-
-
McNaught, K.S.1
Perl, D.P.2
Brownell, A.L.3
-
40
-
-
0032957883
-
Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients
-
Shimura H, Hattori N, Kubo S, et al. Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients. Ann Neurol 1999;45:668-72
-
(1999)
Ann Neurol
, vol.45
, pp. 668-672
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
-
41
-
-
24644448584
-
Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition
-
Bandopadhyay R, Kingsbury AE, Muqit MM, et al. Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition. Neurobiol Dis 2005;20:401-11
-
(2005)
Neurobiol Dis
, vol.20
, pp. 401-411
-
-
Bandopadhyay, R.1
Kingsbury, A.E.2
Muqit, M.M.3
-
42
-
-
0034085796
-
Synphilin-1 is present in Lewy bodies in Parkinson's disease
-
Wakabayashi K, Engelender S, Yoshimoto M, et al. Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann Neurol 2000;47:521-23
-
(2000)
Ann Neurol
, vol.47
, pp. 521-523
-
-
Wakabayashi, K.1
Engelender, S.2
Yoshimoto, M.3
-
43
-
-
0036095285
-
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies
-
Schlossmacher MG, Frosch MP, Gai WP, et al. Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. Am J Pathol 2002;160:1655-67
-
(2002)
Am J Pathol
, vol.160
, pp. 1655-1667
-
-
Schlossmacher, M.G.1
Frosch, M.P.2
Gai, W.P.3
-
44
-
-
0025326719
-
Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases
-
Lowe J, McDermott H, Landon M, et al. Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases. J Pathol 1990;161:153-60
-
(1990)
J Pathol
, vol.161
, pp. 153-160
-
-
Lowe, J.1
McDermott, H.2
Landon, M.3
-
45
-
-
10744224951
-
Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age
-
Pawlyk AC, Giasson BI, Sampathu DM, et al. Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. J Biol Chem 2003;278:48120-28
-
(2003)
J Biol Chem
, vol.278
, pp. 48120-48128
-
-
Pawlyk, A.C.1
Giasson, B.I.2
Sampathu, D.M.3
-
46
-
-
0032568534
-
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
-
Spillantini MG, Crowther RA, Jakes R, et al. α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci USA 1998;95:6469-73
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
-
47
-
-
0036316947
-
Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures
-
McNaught KS, Mytilineou C, Jnobaptiste R, et al. Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. J Neurochem 2002;81:301-6
-
(2002)
J Neurochem
, vol.81
, pp. 301-306
-
-
McNaught, K.S.1
Mytilineou, C.2
Jnobaptiste, R.3
-
48
-
-
1842429946
-
An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein
-
Li H, Seth A. An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein. Oncogene 2004;23:1801-8
-
(2004)
Oncogene
, vol.23
, pp. 1801-1808
-
-
Li, H.1
Seth, A.2
-
49
-
-
1642414402
-
The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases
-
Kitching R, Wong MJ, Koehler D, et al. The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases. Biochim Biophys Acta 2003;1639:104-12
-
(2003)
Biochim Biophys Acta
, vol.1639
, pp. 104-112
-
-
Kitching, R.1
Wong, M.J.2
Koehler, D.3
-
50
-
-
0242407094
-
The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase
-
Subramaniam V, Li H, Wong M, et al. The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase. Br J Cancer 2003;89:1538-44
-
(2003)
Br J Cancer
, vol.89
, pp. 1538-1544
-
-
Subramaniam, V.1
Li, H.2
Wong, M.3
|