메뉴 건너뛰기




Volumn 66, Issue 10, 2007, Pages 955-964

PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain

Author keywords

Lewy bodies; Neurodegeneration; Parkinson disease; Substantia nigra; Synuclein; Ubiquitin proteasome system

Indexed keywords

PROTEIN DERIVATIVE; RING FINGER PROTEIN 11; UNCLASSIFIED DRUG;

EID: 34948881735     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/nen.0b013e3181567f17     Document Type: Article
Times cited : (29)

References (50)
  • 1
    • 14944354884 scopus 로고    scopus 로고
    • Sydney Multicenter Study of Parkinson's disease: Non-L-dopa-responsive problems dominate at 15 years
    • Hely MA, Morris JG, Reid WG, et al. Sydney Multicenter Study of Parkinson's disease: Non-L-dopa-responsive problems dominate at 15 years. Mov Disord 2005;20:190-99
    • (2005) Mov Disord , vol.20 , pp. 190-199
    • Hely, M.A.1    Morris, J.G.2    Reid, W.G.3
  • 2
    • 0242363670 scopus 로고    scopus 로고
    • Molecular pathways of neurodegeneration in Parkinson's disease
    • Dawson TM, Dawson VL. Molecular pathways of neurodegeneration in Parkinson's disease. Science 2003;302:819-22
    • (2003) Science , vol.302 , pp. 819-822
    • Dawson, T.M.1    Dawson, V.L.2
  • 3
    • 0030744876 scopus 로고    scopus 로고
    • Mutation in the α-synuclein gene identified in families with Parkinson's disease
    • Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 1997;276:2045-47
    • (1997) Science , vol.276 , pp. 2045-2047
    • Polymeropoulos, M.H.1    Lavedan, C.2    Leroy, E.3
  • 4
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392:605-8
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1    Asakawa, S.2    Hattori, N.3
  • 5
    • 0032190090 scopus 로고    scopus 로고
    • The ubiquitin pathway in Parkinson's disease
    • Leroy E, Boyer R, Auburger G, et al. The ubiquitin pathway in Parkinson's disease. Nature 1998;395:451-52
    • (1998) Nature , vol.395 , pp. 451-452
    • Leroy, E.1    Boyer, R.2    Auburger, G.3
  • 6
    • 0037428241 scopus 로고    scopus 로고
    • Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
    • Bonifati V, Rizzu P, van Baren MJ, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003;299:256-59
    • (2003) Science , vol.299 , pp. 256-259
    • Bonifati, V.1    Rizzu, P.2    van Baren, M.J.3
  • 7
    • 2442668926 scopus 로고    scopus 로고
    • Hereditary early-onset Parkinson's disease caused by mutations in PINK1
    • Valente EM, Abou-Sleiman PM, Caputo V, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004;304:1158-60
    • (2004) Science , vol.304 , pp. 1158-1160
    • Valente, E.M.1    Abou-Sleiman, P.M.2    Caputo, V.3
  • 8
    • 8844233579 scopus 로고    scopus 로고
    • Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
    • Zimprich A, Biskup S, Leitner P, et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004;44:601-7
    • (2004) Neuron , vol.44 , pp. 601-607
    • Zimprich, A.1    Biskup, S.2    Leitner, P.3
  • 9
    • 24644431901 scopus 로고    scopus 로고
    • LRRK2 gene in Parkinson disease: Mutation analysis and case control association study
    • Paisan-Ruiz C, Lang AE, Kawarai T, et al. LRRK2 gene in Parkinson disease: Mutation analysis and case control association study. Neurology 2005;65:696-700
    • (2005) Neurology , vol.65 , pp. 696-700
    • Paisan-Ruiz, C.1    Lang, A.E.2    Kawarai, T.3
  • 10
    • 0036830525 scopus 로고    scopus 로고
    • A susceptibility gene for late-onset idiopathic Parkinson's disease
    • Hicks AA, Petursson H, Jonsson T, et al. A susceptibility gene for late-onset idiopathic Parkinson's disease. Ann Neurol 2002;52:549-55
    • (2002) Ann Neurol , vol.52 , pp. 549-555
    • Hicks, A.A.1    Petursson, H.2    Jonsson, T.3
  • 11
    • 18344393780 scopus 로고    scopus 로고
    • Age at onset in two common neurodegenerative diseases is genetically controlled
    • Li YJ, Scott WK, Hedges DJ, et al. Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet 2002;70:985-93
    • (2002) Am J Hum Genet , vol.70 , pp. 985-993
    • Li, Y.J.1    Scott, W.K.2    Hedges, D.J.3
  • 12
    • 22544472702 scopus 로고    scopus 로고
    • Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease
    • Oliveira SA, Li YJ, Noureddine MA, et al. Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. Am J Hum Genet 2005;77:252-64
    • (2005) Am J Hum Genet , vol.77 , pp. 252-264
    • Oliveira, S.A.1    Li, Y.J.2    Noureddine, M.A.3
  • 13
    • 27244451809 scopus 로고    scopus 로고
    • High-resolution whole-genome association study of Parkinson disease
    • Maraganore DM, de Andrade M, Lesnick TG, et al. High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet 2005;77:685-93
    • (2005) Am J Hum Genet , vol.77 , pp. 685-693
    • Maraganore, D.M.1    de Andrade, M.2    Lesnick, T.G.3
  • 14
    • 22544469751 scopus 로고    scopus 로고
    • Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra
    • Noureddine MA, Li YJ, van der Walt JM, et al. Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra. Mov Disord 2005;20:1299-1309
    • (2005) Mov Disord , vol.20 , pp. 1299-1309
    • Noureddine, M.A.1    Li, Y.J.2    van der Walt, J.M.3
  • 15
    • 0032760196 scopus 로고    scopus 로고
    • Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein
    • Seki N, Hattori A, Hayashi A, et al. Cloning and expression profile of mouse and human genes, Rnf11/RNF11, encoding a novel RING-H2 finger protein. Biochim Biophys Acta 1999;1489:421-27
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 421-427
    • Seki, N.1    Hattori, A.2    Hayashi, A.3
  • 16
    • 20744435383 scopus 로고    scopus 로고
    • Molecular pathophysiology of Parkinson's disease
    • Moore DJ, West AB, Dawson VL, et al. Molecular pathophysiology of Parkinson's disease. Annu Rev Neurosci 2005;28:57-87
    • (2005) Annu Rev Neurosci , vol.28 , pp. 57-87
    • Moore, D.J.1    West, A.B.2    Dawson, V.L.3
  • 17
    • 0034266806 scopus 로고    scopus 로고
    • RING finger proteins: Mediators of ubiquitin ligase activity
    • Joazeiro CA, Weissman AM. RING finger proteins: Mediators of ubiquitin ligase activity. Cell 2000;102:549-52
    • (2000) Cell , vol.102 , pp. 549-552
    • Joazeiro, C.A.1    Weissman, A.M.2
  • 18
    • 7044238416 scopus 로고    scopus 로고
    • Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
    • Forman MS, Trojanowski JQ, Lee VM. Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 2004;10:1055-63
    • (2004) Nat Med , vol.10 , pp. 1055-1063
    • Forman, M.S.1    Trojanowski, J.Q.2    Lee, V.M.3
  • 19
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-86
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3
  • 21
    • 0036522982 scopus 로고    scopus 로고
    • Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice
    • Zhang W, Basile AS, Gomeza J, et al. Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice. J Neurosci 2002;22:1709-17
    • (2002) J Neurosci , vol.22 , pp. 1709-1717
    • Zhang, W.1    Basile, A.S.2    Gomeza, J.3
  • 22
    • 0036322266 scopus 로고    scopus 로고
    • Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
    • Duda JE, Giasson BI, Mabon ME, et al. Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases. Ann Neurol 2002;52:205-10
    • (2002) Ann Neurol , vol.52 , pp. 205-210
    • Duda, J.E.1    Giasson, B.I.2    Mabon, M.E.3
  • 23
    • 0028936065 scopus 로고
    • The dopamine transporter: Immunochemical characterization and localization in brain
    • Ciliax BJ, Heilman C, Demchyshyn LL, et al. The dopamine transporter: Immunochemical characterization and localization in brain. J Neurosci 1995;15:1714-23
    • (1995) J Neurosci , vol.15 , pp. 1714-1723
    • Ciliax, B.J.1    Heilman, C.2    Demchyshyn, L.L.3
  • 24
    • 0020692977 scopus 로고
    • Monoclonal antibodies to choline acetyltransferase: Production, specificity, and immunohistochemistry
    • Levey AI, Armstrong DM, Atweh SF, et al. Monoclonal antibodies to choline acetyltransferase: Production, specificity, and immunohistochemistry. J Neurosci 1983;3:1-9
    • (1983) J Neurosci , vol.3 , pp. 1-9
    • Levey, A.I.1    Armstrong, D.M.2    Atweh, S.F.3
  • 25
  • 26
    • 0033030440 scopus 로고    scopus 로고
    • Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease
    • Miller GW, Erickson JD, Perez JT, et al. Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Exp Neurol 1999;156:138-48
    • (1999) Exp Neurol , vol.156 , pp. 138-148
    • Miller, G.W.1    Erickson, J.D.2    Perez, J.T.3
  • 27
    • 0027465882 scopus 로고
    • Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain
    • Levey AI. Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain. Life Sci 1993;52:441-48
    • (1993) Life Sci , vol.52 , pp. 441-448
    • Levey, A.I.1
  • 28
    • 0033933871 scopus 로고    scopus 로고
    • 5 receptor immunolocalization in rat and monkey brain
    • 5 receptor immunolocalization in rat and monkey brain. Synapse 2000;37:125-45
    • (2000) Synapse , vol.37 , pp. 125-145
    • Ciliax, B.J.1    Nash, N.2    Heilman, C.3
  • 29
    • 0033961490 scopus 로고    scopus 로고
    • Expression of α-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease
    • Solano SM, Miller DW, Augood SJ, et al. Expression of α-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease. Ann Neurol 2000;47:201-10
    • (2000) Ann Neurol , vol.47 , pp. 201-210
    • Solano, S.M.1    Miller, D.W.2    Augood, S.J.3
  • 30
    • 0031944830 scopus 로고    scopus 로고
    • Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity
    • Irizarry MC, Growdon W, Gomez-Isla T, et al. Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity. J Neuropathol Exp Neurol 1998;57:334-37
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 334-337
    • Irizarry, M.C.1    Growdon, W.2    Gomez-Isla, T.3
  • 31
    • 0020630852 scopus 로고
    • Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis
    • Doran JF, Jackson P, Kynoch PA, et al. Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis. J Neurochem 1983;40:1542-47
    • (1983) J Neurochem , vol.40 , pp. 1542-1547
    • Doran, J.F.1    Jackson, P.2    Kynoch, P.A.3
  • 32
    • 10744224738 scopus 로고    scopus 로고
    • The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
    • Bandopadhyay R, Kingsbury AE, Cookson MR, et al. The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. Brain 2004;127:420-30
    • (2004) Brain , vol.127 , pp. 420-430
    • Bandopadhyay, R.1    Kingsbury, A.E.2    Cookson, M.R.3
  • 33
    • 13844253723 scopus 로고    scopus 로고
    • Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1
    • Goldberg MS, Pisani A, Haburcak M, et al. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron 2005;45:489-96
    • (2005) Neuron , vol.45 , pp. 489-496
    • Goldberg, M.S.1    Pisani, A.2    Haburcak, M.3
  • 34
    • 0037431172 scopus 로고    scopus 로고
    • Parkin: A multipurpose neuroprotective agent?
    • Feany MB, Pallanck LJ. Parkin: A multipurpose neuroprotective agent? Neuron 2003;38:13-16
    • (2003) Neuron , vol.38 , pp. 13-16
    • Feany, M.B.1    Pallanck, L.J.2
  • 35
    • 0035664746 scopus 로고    scopus 로고
    • α-Synuclein and cytosolic dopamine: Stabilizing a bad situation
    • Sulzer D. α-Synuclein and cytosolic dopamine: Stabilizing a bad situation. Nat Med 2001;7:1280-82
    • (2001) Nat Med , vol.7 , pp. 1280-1282
    • Sulzer, D.1
  • 36
    • 0033681149 scopus 로고    scopus 로고
    • Chronic systemic pesticide exposure reproduces features of Parkinson's disease
    • Betarbet R, Sherer TB, MacKenzie G, et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000;3:1301-6
    • (2000) Nat Neurosci , vol.3 , pp. 1301-1306
    • Betarbet, R.1    Sherer, T.B.2    MacKenzie, G.3
  • 37
    • 0037036904 scopus 로고    scopus 로고
    • Proteasome inhibition causes nigral degeneration with inclusion bodies in rats
    • McNaught KS, Bjorklund LM, Belizaire R, et al. Proteasome inhibition causes nigral degeneration with inclusion bodies in rats. Neuroreport 2002;13:1437-41
    • (2002) Neuroreport , vol.13 , pp. 1437-1441
    • McNaught, K.S.1    Bjorklund, L.M.2    Belizaire, R.3
  • 38
    • 3042794162 scopus 로고    scopus 로고
    • Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease
    • McNaught KS, Perl DP, Brownell AL, et al. Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Ann Neurol 2004;56:149-62
    • (2004) Ann Neurol , vol.56 , pp. 149-162
    • McNaught, K.S.1    Perl, D.P.2    Brownell, A.L.3
  • 40
    • 0032957883 scopus 로고    scopus 로고
    • Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients
    • Shimura H, Hattori N, Kubo S, et al. Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients. Ann Neurol 1999;45:668-72
    • (1999) Ann Neurol , vol.45 , pp. 668-672
    • Shimura, H.1    Hattori, N.2    Kubo, S.3
  • 41
    • 24644448584 scopus 로고    scopus 로고
    • Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition
    • Bandopadhyay R, Kingsbury AE, Muqit MM, et al. Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition. Neurobiol Dis 2005;20:401-11
    • (2005) Neurobiol Dis , vol.20 , pp. 401-411
    • Bandopadhyay, R.1    Kingsbury, A.E.2    Muqit, M.M.3
  • 42
    • 0034085796 scopus 로고    scopus 로고
    • Synphilin-1 is present in Lewy bodies in Parkinson's disease
    • Wakabayashi K, Engelender S, Yoshimoto M, et al. Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann Neurol 2000;47:521-23
    • (2000) Ann Neurol , vol.47 , pp. 521-523
    • Wakabayashi, K.1    Engelender, S.2    Yoshimoto, M.3
  • 43
    • 0036095285 scopus 로고    scopus 로고
    • Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies
    • Schlossmacher MG, Frosch MP, Gai WP, et al. Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. Am J Pathol 2002;160:1655-67
    • (2002) Am J Pathol , vol.160 , pp. 1655-1667
    • Schlossmacher, M.G.1    Frosch, M.P.2    Gai, W.P.3
  • 44
    • 0025326719 scopus 로고
    • Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases
    • Lowe J, McDermott H, Landon M, et al. Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases. J Pathol 1990;161:153-60
    • (1990) J Pathol , vol.161 , pp. 153-160
    • Lowe, J.1    McDermott, H.2    Landon, M.3
  • 45
    • 10744224951 scopus 로고    scopus 로고
    • Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age
    • Pawlyk AC, Giasson BI, Sampathu DM, et al. Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. J Biol Chem 2003;278:48120-28
    • (2003) J Biol Chem , vol.278 , pp. 48120-48128
    • Pawlyk, A.C.1    Giasson, B.I.2    Sampathu, D.M.3
  • 46
    • 0032568534 scopus 로고    scopus 로고
    • α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
    • Spillantini MG, Crowther RA, Jakes R, et al. α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci USA 1998;95:6469-73
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6469-6473
    • Spillantini, M.G.1    Crowther, R.A.2    Jakes, R.3
  • 47
    • 0036316947 scopus 로고    scopus 로고
    • Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures
    • McNaught KS, Mytilineou C, Jnobaptiste R, et al. Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. J Neurochem 2002;81:301-6
    • (2002) J Neurochem , vol.81 , pp. 301-306
    • McNaught, K.S.1    Mytilineou, C.2    Jnobaptiste, R.3
  • 48
    • 1842429946 scopus 로고    scopus 로고
    • An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein
    • Li H, Seth A. An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein. Oncogene 2004;23:1801-8
    • (2004) Oncogene , vol.23 , pp. 1801-1808
    • Li, H.1    Seth, A.2
  • 49
    • 1642414402 scopus 로고    scopus 로고
    • The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases
    • Kitching R, Wong MJ, Koehler D, et al. The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases. Biochim Biophys Acta 2003;1639:104-12
    • (2003) Biochim Biophys Acta , vol.1639 , pp. 104-112
    • Kitching, R.1    Wong, M.J.2    Koehler, D.3
  • 50
    • 0242407094 scopus 로고    scopus 로고
    • The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase
    • Subramaniam V, Li H, Wong M, et al. The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase. Br J Cancer 2003;89:1538-44
    • (2003) Br J Cancer , vol.89 , pp. 1538-1544
    • Subramaniam, V.1    Li, H.2    Wong, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.