Calorimetric investigation of phosphorylated and non-phosphorylated peptide ligand binding to the human Grb7-SH2 domain

Journal of Molecular Recognition

Volumn 20, Issue 4, 2007, Pages 245-252

  Spuches, A M ^d   Argiros, H J ^b   Lee, K H ^b   Lowell Haas, L ^b   Pero, S C ^c   Krag, D N ^c   Roller, P P ^a   Wilcox, D E ^d   Lyons, B A ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NEW MEXICO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF VERMONT   (United States)

^d Dartmouth College   (United States)

Author keywords

erbB2; Grb7; Isothermal titration calorimetry; Ligand binding; Protein recognition; SH2 domain; Thermodynamics

Indexed keywords

ALANINE; EPHRIN RECEPTOR B1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; GRB7 PROTEIN, HUMAN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 7; LIGAND; MUTANT PROTEIN; PEPTIDE FRAGMENT; PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; SRC HOMOLOGY DOMAIN; THERMODYNAMICS;

ALANINE; CALORIMETRY; GRB7 ADAPTOR PROTEIN; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTANT PROTEINS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; RECEPTOR, EPHB1; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; SRC HOMOLOGY DOMAINS; THERMODYNAMICS;

EID: 34948870448     PISSN: 09523499     EISSN: 10991352     Source Type: Journal    
DOI: 10.1002/jmr.834     Document Type: Article

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