메뉴 건너뛰기




Volumn 26, Issue 45, 2007, Pages 6546-6559

SH2B1β adaptor is a key enhancer of RET tyrosine kinase signaling

Author keywords

RET; SH2B1; Signaling

Indexed keywords

PHOSPHOTRANSFERASE; PROTEIN RET; PROTEIN SH2; PROTEIN TYROSINE PHOSPHATASE; SRC HOMOLOGY 2 DOMAIN PROTEIN B1 BETA; UNCLASSIFIED DRUG; ISOPROTEIN; RET PROTEIN, HUMAN; SH2B1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 34948858980     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210480     Document Type: Article
Times cited : (24)

References (47)
  • 1
    • 0034872381 scopus 로고    scopus 로고
    • Functional effects of APS and SH2-B on insulin receptor signalling
    • Ahmed Z, Pillay TS. (2001). Functional effects of APS and SH2-B on insulin receptor signalling. Biochem Soc Trans 29: 529-534.
    • (2001) Biochem Soc Trans , vol.29 , pp. 529-534
    • Ahmed, Z.1    Pillay, T.S.2
  • 2
    • 0037627342 scopus 로고    scopus 로고
    • Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling
    • Ahmed Z, Pillay TS. (2003). Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling. Biochem J 371: 405-412.
    • (2003) Biochem J , vol.371 , pp. 405-412
    • Ahmed, Z.1    Pillay, T.S.2
  • 3
    • 0036581222 scopus 로고    scopus 로고
    • The GDNF family: Signalling, biological functions and therapeutic value
    • Airaksinen MS, Saarma M. (2002). The GDNF family: signalling, biological functions and therapeutic value. Nat Rev Neurosci 3: 383-394.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 383-394
    • Airaksinen, M.S.1    Saarma, M.2
  • 6
    • 22544456020 scopus 로고    scopus 로고
    • RET tyrosine kinase signaling in development and cancer
    • Arighi E, Borrello MG, Sariola H. (2005). RET tyrosine kinase signaling in development and cancer. Cytokine Growth F R 16: 441-467.
    • (2005) Cytokine Growth F R , vol.16 , pp. 441-467
    • Arighi, E.1    Borrello, M.G.2    Sariola, H.3
  • 7
    • 0032962930 scopus 로고    scopus 로고
    • A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation
    • Besser D, Bromberg JF, Darnell Jr JE, Hanafusa H. (1999). A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation. Mol Cell Biol 19: 1401-1409.
    • (1999) Mol Cell Biol , vol.19 , pp. 1401-1409
    • Besser, D.1    Bromberg, J.F.2    Darnell Jr, J.E.3    Hanafusa, H.4
  • 8
    • 0027523909 scopus 로고
    • Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RIa of cyclic AMP-dependent protein kinase A
    • Bongarzone I, Monzini N, Borrello MG, Carcano C, Ferraresi G, Arighi E et al. (1993). Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RIa of cyclic AMP-dependent protein kinase A. Mol Cell Biol 13: 358-366.
    • (1993) Mol Cell Biol , vol.13 , pp. 358-366
    • Bongarzone, I.1    Monzini, N.2    Borrello, M.G.3    Carcano, C.4    Ferraresi, G.5    Arighi, E.6
  • 9
    • 9244251611 scopus 로고    scopus 로고
    • The full oncogenic activity of Ret/ ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma
    • Borrello MG, Alberti L, Arighi E, Bongarzone I, Battistini C, Bardelli A et al. (1996). The full oncogenic activity of Ret/ ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma. Mol Cell Biol 16: 2151-2163.
    • (1996) Mol Cell Biol , vol.16 , pp. 2151-2163
    • Borrello, M.G.1    Alberti, L.2    Arighi, E.3    Bongarzone, I.4    Battistini, C.5    Bardelli, A.6
  • 12
    • 0031000793 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human VGF promoter region
    • Canu N, Possenti R, Rinaldi AM, Trani E, Levi A. (1997). Molecular cloning and characterization of the human VGF promoter region. J Neurochem 68: 1390-1399.
    • (1997) J Neurochem , vol.68 , pp. 1390-1399
    • Canu, N.1    Possenti, R.2    Rinaldi, A.M.3    Trani, E.4    Levi, A.5
  • 14
    • 3242735120 scopus 로고    scopus 로고
    • Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma
    • Cuccuru G, Lanzi C, Cassinelli G, Pratesi G, Tortoreto M, Petrangolini G et al. (2004). Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma. J Natl Cancer Inst 96: 1006-1014.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1006-1014
    • Cuccuru, G.1    Lanzi, C.2    Cassinelli, G.3    Pratesi, G.4    Tortoreto, M.5    Petrangolini, G.6
  • 15
    • 0035883740 scopus 로고    scopus 로고
    • Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis
    • de Graaff E, Srinivas S, KilKenny C, D'Agati V, Mankoo BS, Costantini F et al. (2001). Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. Genes Dev 15: 2433-2444.
    • (2001) Genes Dev , vol.15 , pp. 2433-2444
    • de Graaff, E.1    Srinivas, S.2    KilKenny, C.3    D'Agati, V.4    Mankoo, B.S.5    Costantini, F.6
  • 18
    • 4344581405 scopus 로고    scopus 로고
    • Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance
    • Duan C, Yang H, White MF, Rui L. (2004). Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance. Mol Cell Biol 24: 7435-7443.
    • (2004) Mol Cell Biol , vol.24 , pp. 7435-7443
    • Duan, C.1    Yang, H.2    White, M.F.3    Rui, L.4
  • 19
    • 33750318892 scopus 로고    scopus 로고
    • Ret oncoproteins induce tyrosine phosphorylation changes of proteins involved in RNA metabolism
    • Gorla L, Cantu M, Micciche' F, Patelli C, Mondellini P, Pierotti MA et al. (2006). Ret oncoproteins induce tyrosine phosphorylation changes of proteins involved in RNA metabolism. Cell Signal 18: 2272-2282.
    • (2006) Cell Signal , vol.18 , pp. 2272-2282
    • Gorla, L.1    Cantu, M.2    Micciche', F.3    Patelli, C.4    Mondellini, P.5    Pierotti, M.A.6
  • 20
    • 0034688340 scopus 로고    scopus 로고
    • Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-independent cell survival and neuronal differentiation
    • Gryz EA, Meakin SO. (2000). Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-independent cell survival and neuronal differentiation. Oncogene 19: 417-430.
    • (2000) Oncogene , vol.19 , pp. 417-430
    • Gryz, E.A.1    Meakin, S.O.2
  • 21
  • 22
    • 0346156078 scopus 로고    scopus 로고
    • Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor
    • Hu J, Liu J, Ghirlando R, Saltiel AR, Hubbard SR. (2003). Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol Cell 12: 1379-1389.
    • (2003) Mol Cell , vol.12 , pp. 1379-1389
    • Hu, J.1    Liu, J.2    Ghirlando, R.3    Saltiel, A.R.4    Hubbard, S.R.5
  • 24
    • 11144355646 scopus 로고    scopus 로고
    • Identification of RET autophosphorylation sites by mass spectrometry
    • Kawamoto Y, Takeda K, Okuno Y, Yamakawa Y, Ito Y, Taguchi R et al. (2004). Identification of RET autophosphorylation sites by mass spectrometry. J Biol Chem 279: 14213-14224.
    • (2004) J Biol Chem , vol.279 , pp. 14213-14224
    • Kawamoto, Y.1    Takeda, K.2    Okuno, Y.3    Yamakawa, Y.4    Ito, Y.5    Taguchi, R.6
  • 25
    • 0037013284 scopus 로고    scopus 로고
    • Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation
    • Kong M, Wang CS, Donoghue DJ. (2002). Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation. J Biol Chem 277: 15962-15970.
    • (2002) J Biol Chem , vol.277 , pp. 15962-15970
    • Kong, M.1    Wang, C.S.2    Donoghue, D.J.3
  • 26
    • 0032189383 scopus 로고    scopus 로고
    • SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase
    • Kotani K, Wilden P, Pillay TS. (1998). SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase. Biochem J 335: 103-109.
    • (1998) Biochem J , vol.335 , pp. 103-109
    • Kotani, K.1    Wilden, P.2    Pillay, T.S.3
  • 28
    • 0033548548 scopus 로고    scopus 로고
    • pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells
    • Lee RJ, Albanese C, Stenger RJ, Watanabe G, Inghirami G, Haines GK et al. (1999). pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells. J Biol Chem 274: 7341-7350.
    • (1999) J Biol Chem , vol.274 , pp. 7341-7350
    • Lee, R.J.1    Albanese, C.2    Stenger, R.J.3    Watanabe, G.4    Inghirami, G.5    Haines, G.K.6
  • 29
    • 0031038795 scopus 로고    scopus 로고
    • Lorenzo MJ, Gish GD, Houghton C, Stonehouse TJ, Pawson T, Ponder BAJ et al. (1997). RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2. Oncogene 14: 763-771.
    • Lorenzo MJ, Gish GD, Houghton C, Stonehouse TJ, Pawson T, Ponder BAJ et al. (1997). RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2. Oncogene 14: 763-771.
  • 30
    • 0032726331 scopus 로고    scopus 로고
    • Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain
    • Nelms K, O'Neill TJ, Li S, Hubbard SR, Gustafson TA, Paul WE. (1999). Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain. Mamm Genome 10: 1160-1167.
    • (1999) Mamm Genome , vol.10 , pp. 1160-1167
    • Nelms, K.1    O'Neill, T.J.2    Li, S.3    Hubbard, S.R.4    Gustafson, T.A.5    Paul, W.E.6
  • 31
    • 0038146905 scopus 로고    scopus 로고
    • YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling
    • O'Brien KB, Argetsinger LS, DiakonovaM, Carter-Su C. (2003). YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling. J Biol Chem 278: 11970-11978.
    • (2003) J Biol Chem , vol.278 , pp. 11970-11978
    • O'Brien, K.B.1    Argetsinger, L.S.2    DiakonovaM3    Carter-Su, C.4
  • 33
    • 0028802599 scopus 로고
    • The yeast tribrid system-genetic detection of trans-phosphorylated ITAM-SH2-interactions
    • Osborne MA, Dalton S, Kochan JP. (1995). The yeast tribrid system-genetic detection of trans-phosphorylated ITAM-SH2-interactions. Biotechnology 13: 1474-1478.
    • (1995) Biotechnology , vol.13 , pp. 1474-1478
    • Osborne, M.A.1    Dalton, S.2    Kochan, J.P.3
  • 34
    • 0035131695 scopus 로고    scopus 로고
    • SH2-B and APS are multimeric adapters that augment trkA signaling
    • Qian X, Ginty DD. (2001). SH2-B and APS are multimeric adapters that augment trkA signaling. Mol Cell Biol 21: 1613-1620.
    • (2001) Mol Cell Biol , vol.21 , pp. 1613-1620
    • Qian, X.1    Ginty, D.D.2
  • 35
    • 0032418850 scopus 로고    scopus 로고
    • Identification and characterization of novel substrates of Trk receptors in developing neurons
    • Qian X, Riccio A, Zhang Y, Ginty DD. (1998). Identification and characterization of novel substrates of Trk receptors in developing neurons. Neuron 21: 1017-1029.
    • (1998) Neuron , vol.21 , pp. 1017-1029
    • Qian, X.1    Riccio, A.2    Zhang, Y.3    Ginty, D.D.4
  • 36
    • 0035474473 scopus 로고    scopus 로고
    • Signaling via Shc family adapter proteins
    • Ravichandran KS. (2001). Signaling via Shc family adapter proteins. Oncogene 20: 6322-6330.
    • (2001) Oncogene , vol.20 , pp. 6322-6330
    • Ravichandran, K.S.1
  • 37
    • 25144523930 scopus 로고    scopus 로고
    • Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice
    • Ren D, Li M, Duan C, Rui L. (2005). Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice. Cell Metab 2: 95-104.
    • (2005) Cell Metab , vol.2 , pp. 95-104
    • Ren, D.1    Li, M.2    Duan, C.3    Rui, L.4
  • 38
    • 0031474386 scopus 로고    scopus 로고
    • Riedel H, Wang J, Hansen H, Yousaf N. (1997). PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor. J Biochem (Tokyo) 122: 1105-1113.
    • Riedel H, Wang J, Hansen H, Yousaf N. (1997). PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor. J Biochem (Tokyo) 122: 1105-1113.
  • 39
    • 13544254259 scopus 로고    scopus 로고
    • Analysis of SHP-1 mediated downregulation of the TRK-T3 oncoprotein identifies TFG as a novel SHP-1 interacting protein
    • Roccato E, Miranda C, Raho G, Pagliardini S, Pierotti MA, Greco A. (2005). Analysis of SHP-1 mediated downregulation of the TRK-T3 oncoprotein identifies TFG as a novel SHP-1 interacting protein. J Biol Chem 280: 3382-3389.
    • (2005) J Biol Chem , vol.280 , pp. 3382-3389
    • Roccato, E.1    Miranda, C.2    Raho, G.3    Pagliardini, S.4    Pierotti, M.A.5    Greco, A.6
  • 40
    • 0032516879 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta
    • Rui L, Carter-Su C. (1998). Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta. J Biol Chem 273: 21239-21245.
    • (1998) J Biol Chem , vol.273 , pp. 21239-21245
    • Rui, L.1    Carter-Su, C.2
  • 41
    • 0033594812 scopus 로고    scopus 로고
    • Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2
    • Rui L, Carter-Su C. (1999). Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2. Proc Natl Acad Sci USA 96: 7172-7177.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7172-7177
    • Rui, L.1    Carter-Su, C.2
  • 42
    • 0034004130 scopus 로고    scopus 로고
    • Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-Bbeta
    • Rui L, Gunter DR, Herrington J, Carter-Su C. (2000). Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-Bbeta. Mol Cell Biol 20: 3168-3177.
    • (2000) Mol Cell Biol , vol.20 , pp. 3168-3177
    • Rui, L.1    Gunter, D.R.2    Herrington, J.3    Carter-Su, C.4
  • 43
    • 0030613545 scopus 로고    scopus 로고
    • Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling
    • Rui L, Mathews LS, Hotta K, Gustafson TA, Carter-Su C. (1997). Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling. Mol Cell Biol 17: 6633-6644.
    • (1997) Mol Cell Biol , vol.17 , pp. 6633-6644
    • Rui, L.1    Mathews, L.S.2    Hotta, K.3    Gustafson, T.A.4    Carter-Su, C.5
  • 44
    • 0034849573 scopus 로고    scopus 로고
    • The GDNF/RET signaling pathway and human diseases
    • Takahashi M. (2001). The GDNF/RET signaling pathway and human diseases. Cytokine Growth F 12: 361-373.
    • (2001) Cytokine Growth F , vol.12 , pp. 361-373
    • Takahashi, M.1
  • 45
    • 0032488916 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter
    • Wang J, Riedel H. (1998). Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter. J Biol Chem 273: 3136-3139.
    • (1998) J Biol Chem , vol.273 , pp. 3136-3139
    • Wang, J.1    Riedel, H.2
  • 46
    • 0035798534 scopus 로고    scopus 로고
    • Four PSM/ SH2-B alternative splice variants and their differential roles in mitogenesis
    • Yousaf N, Deng Y, Kang Y, Riedel H. (2001). Four PSM/ SH2-B alternative splice variants and their differential roles in mitogenesis. J Biol Chem 276: 40940-40948.
    • (2001) J Biol Chem , vol.276 , pp. 40940-40948
    • Yousaf, N.1    Deng, Y.2    Kang, Y.3    Riedel, H.4
  • 47
    • 33646680812 scopus 로고    scopus 로고
    • Interaction of SH2-B{beta} with RET is involved in signaling of GDNF-induced neurite outgrowth
    • Zhang Y, Zhu W, Wang YG, Liu XJ, Jiao L, Liu X et al. (2006). Interaction of SH2-B{beta} with RET is involved in signaling of GDNF-induced neurite outgrowth. J Cell Sci 119: 1666-1676.
    • (2006) J Cell Sci , vol.119 , pp. 1666-1676
    • Zhang, Y.1    Zhu, W.2    Wang, Y.G.3    Liu, X.J.4    Jiao, L.5    Liu, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.