Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-independent cell survival and neuronal differentiation

Oncogene

Volumn 19, Issue 3, 2000, Pages 417-430

  Gryz, Ela A ^a,b   Meakin, Susan O ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Activation loop; Kinase activation; Nerve growth factor; Neurotrophins; TrkA; Tyrosine kinase receptor

Indexed keywords

NERVE GROWTH FACTOR; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; TYROSINE;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; LIGAND BINDING; MEDULLOBLASTOMA; NERVE CELL DIFFERENTIATION; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0034688340     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203330     Document Type: Article

References (56)

1. Alessi DR, Saito Y, Campbell DG, Cohen P, Sithanandam G, Rapp U, Ashworth A, Marshall CJ and Cowley S. (1994). EMBO J., 13, 1610-1619.
2. Baxter RM, Cohen P, Obermeier A, Ullrich A, Downes CP and Doza YN. (1995). Eur. J. Biochem., 234, 84-91.
3. Brunet A, Pagès G and Pouysségur J. (1994). Oncogene, 9, 3379-3387.
4. Cowley SJ, Paterson H, Kemp P and Marshall CJ. (1994). Cell, 77, 841-852.
5. Cunningham ME, Stephens RM, Kaplan DR and Greene LA. (1997). J. Biol. Chem., 272, 10957-10967.
6. Ellis L, Clauser E, Morgan DO, Edery M, Roth RA and Rutter WJ. (1986). Cell, 45, 721-732.
7. Glass DJ and Yancopoulos GD. (1993). TICB, 3, 262-268.
8. Goldsmith BA and Koizumi S. (1997). J. Neurochem., 69, 1014-1019.
9. Gossen M, Freundlieb S, Bender G, Müller G, Hillen W and Bujard H. (1995). Science, 268, 1766-1769.
10. Gossen N and Bujard H. (1992). Proc. Natl. Acad. Sci. USA, 89, 5547-5551.
11. Green SH and Greene LA. (1986). J. Biol. Chem., 261, 15316-15326.
12. Hallberg B, Asheroft M, Loeb DM, Kaplan DR and Downward J. (1998). Oncogene, 17, 691-697.
13. Hanks SK, Quinn AM and Hunter T. (1988). Science, 241, 42-52.
14. Heldin C-H. (1995). Cell, 80, 213-223.
15. Hernandez-Sanchez C, Blakesley V, Kalebic T, Helman L and LeRoith D. (1995). J. Biol. Chem., 270, 29176-29181.
16. Hubbard SR. (1997). EMBO J., 16, 5572-5581.
17. Hubbard SR, Wei L, Ellis L and Hendrickson WA. (1994). Nature, 372, 746-754.
18. Kaplan DR and Miller FD. (1997). Curr. Opin. Cell. Biol., 9, 213-221.
19. Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I and Schlessinger J. (1997). Cell, 89, 693-702.
20. Li Y, Basilico C and Mansukhani A. (1994). Mol. Cell. Biol., 14, 7660-7669.
21. Loeb DM, Maragos J, Martín-Zanca D, Chao MV, Parada LF and Greene LA. (1991). Cell, 66, 961-966.
22. Loeb DM, Stephens RM, Copeland T, Kaplan DR and Greene LA. (1994). J. Biol. Chem., 269, 8901-8910.
23. Longati P, Bardelli A, Ponzetto C, Naldini L and Comoglio PM. (1994). Oncogene, 9, 49-57.
24. MacDonald JIS and Meakin SO. (1996). Mol. Cell. Neurosci., 7, 371-390.
25. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Woude GFV and Ahn NG. (1994). Science, 265, 966-970.
26. Martin-Zanca D, Oskam R, Mitra G, Copeland T and Barbacid M. (1989). Mol. Cell. Biol., 9, 24-33.
27. Matsushima H and Bogenmann E. (1993). Mol. Cell. Biol., 13, 7447-7456.
28. McCarty JH and Feinstein SC. (1998). Oncogene, 16, 1691-1700.
29. Meakin SO and MacDonald JIS. (1998). J. Neurochem., 71, 1875-1888.
30. Meakin SO and Shooter EM. (1991). Proc. Natl. Acad. Sci. USA, 88, 5862-5866.
31. Meakin SO and Shooter EM. (1992). TINS, 15, 323-331.
32. Meakin SO, Gryz EA and MacDonald JIS. (1997). J. Neurochem., 69, 954-967.
33. Meakin SO, MacDonald JIS, Gryz EA, Kubu CJ and Verdi JM. (1999). J. Biol. Chem., 274, 9861-9870.
34. Mohammadi M, Schlessinger J and Hubbard SR. (1996). Cell, 86, 577-587.
35. Morooka T and Nishida E. (1998). J. Biol. Chem., 273, 24285-24288.
36. Muragaki Y, Chou TT, Kaplan DR, Trojanowski JQ and Lee VM-Y. (1997). J. Neurosci., 17, 530-542.
37. Obermeier A, Bradshaw RA, Seedorf K, Choidas A, Schlessinger J and Ullrich A. (1994). EMBO J., 13, 1585-1590.
38. Obermeier A, Lammers R, Wiesmuller K-H, Jung G, Schlessinger J and Ullrich A. (1993). J. Biol. Chem., 268, 22963-22966.
39. Poluha W, Poluha DK and Ross AH. (1995). Oncogene, 10, 185-189.
40. Qian X, Riccio A, Zhang Y and Ginty DD. (1998). Neuron, 21, 1017-1029.
41. Rabin SJ, Cleghon V and Kaplan DR. (1993). Mol. Cell. Biol., 13, 2203-2213.
42. Raffioni S, Zhu Y-Z, Bradshaw RA and Thompson LM. (1998). J. Biol. Chem., 273, 35250-35259.
43. Robbins DJ, Zhen E, Owaki H, Vanderbilt CA, Ebert D, Geppert TD and Cobb MH. (1993). J. Biol. Chem., 268, 5097-5106.
44. Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD and Downward J. (1994). Nature, 370, 527-532.
45. Schlessinger J and Ullrich A. (1991). Neuron, 9, 383-391.
46. Stannard B, Blakesley V, Kato H, Roberts CTJ and LeRoith D. (1995). Endocrinology, 136, 4918-4924.
47. Stephens RM, Loeb DM, Copeland TD, Pawson T, Greene LA and Kaplan DR. (1994). Neuron, 12, 691-705.
48. Webster MK, D'Avis PY, Robertson SC and Donoghue DJ. (1996). Mol. Cell. Biol., 16, 4081-4087.
49. Weinmaster G and Pawson T. (1986). J. Biol. Chem., 261, 328-333.
50. Wilden PA, Kahn CR, Siddle K and White MF. (1992). J. Biol. Chem., 267, 16660-16668.
51. Woods D, Parry D, Cherwinski H, Bosch E, Lees E and McMahon M. (1997). Mol. Cell. Biol., 17, 5598-5611.
52. Wright JH, Drueckes P, Bartoe J, Zhao Z, Shen S-H and Krebs EG. (1997). Mol. Biol. Cell, 8, 1575-1585.
53. Yamashita H, Avraham S, Jiang S, Dikic I and Avraham H. (1999). J. Biol. Chem., 274, 15059-15065.
54. Yao R and Cooper GM. (1995). Science, 267, 2003-2006.
55. York RD, Yao H, Dillon T, Ellig CL, Eckert SP, McClecksy EW and Stork PJ. (1998). Nature, 392, 622-626.
56. Zhang B, Tavare JM, Ellis L and Roth RA. (1991). J. Biol. Chem., 266, 990-996.