Interaction of plasma homocysteine and thyroid hormone concentrations in the pathogenesis of the slow coronary flow phenomenon

Cardiology

Volumn 108, Issue 3, 2007, Pages 186-192

  Evrengul, Harun ^a,c   Tanriverdi, Halil ^a   Enli, Yasar ^a   Kuru, Omur ^a   Seleci, Deniz ^a   Bastemir, Mehmet ^a   Kilic, Ayhan ^b   Kaftan, Asuman ^a   Kilic, Mustafa ^a  

^a PAMUKKALE UNIVERSITY   (Turkey)

^b GULHANE SCHOOL OF MEDICINE   (Turkey)

^c NONE   (Turkey)

Author keywords

Homocysteine; Slow coronary flow; Thyroid hormones

Indexed keywords

HOMOCYSTEINE; LIOTHYRONINE; THYROID HORMONE; THYROXINE;

ADULT; AMINO ACID BLOOD LEVEL; ANGIOCARDIOGRAPHY; ARTICLE; BLOOD CHEMISTRY; BLOOD CLOT LYSIS; CARDIOVASCULAR RISK; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; CORONARY RISK; CORRELATION ANALYSIS; DEMOGRAPHY; FEMALE; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR INTERACTION; MULTIPLE REGRESSION; PATHOGENESIS; PRIORITY JOURNAL; SLOW CORONARY FLOW PHENOMENON; STATISTICAL SIGNIFICANCE; THYROID HORMONE BLOOD LEVEL; VARIANCE;

AGED; ANGINA PECTORIS; BLOOD FLOW VELOCITY; CASE-CONTROL STUDIES; CORONARY ANGIOGRAPHY; CORONARY CIRCULATION; ENDOTHELIUM, VASCULAR; FEMALE; HOMOCYSTEINE; HUMANS; MALE; MIDDLE AGED; THYROID HORMONES; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE;

EID: 34948849822     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000096687     Document Type: Article

References (42)

1. Tambe AA, Demany MA, Zimmerman HA, Masearanhas E: Angina pectoris and slow flow velocity of dye in coronary arteries, a new angiographic finding. Am Heart J 1972;84:66-71.
2. Sezgin AT, Sigirci A, Barutcu I, et al: Vascular endothelial function in patients with slow coronary flow. Coron Artery Dis 2003;14:155-161.
3. Erbay AR, Turhan H, Yasar AS, et al: Elevated level of plasma homocysteine in patients with slow coronary flow. Int J Cardiol 2005;102:419-423.
4. Barutcu I, Sezgin AT, Sezgin N, et al: Elevated plasma homocysteine level in slow coronary flow. Int J Cardiol 2005;101:143-145.
5. Woo KS, Chook P, Lolin YI: Hyperhomocyst(e)inemia is a risk factor for arterial endothelial dysfunction in humans. Circulation 1997;96:2542-2544.
6. Graham IM, Daly LE, Refsum HM, et al: Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project. JAMA 1997;277:1775-1778.
7. Tawakol A, Omland T, Gerhard M, et al: Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation 1997;95:1119-1121.
8. Pekdemir H, Cin VG, Cicek D, et al: Slow coronary flow may be a sign of diffuse atherosclerosis: contribution of FFR and IVUS. Acta Cardiol 2004;59:127-133.
9. Vrints C, Herman AG: Role of the endothelium in the regulation of coronary artery tone. Acta Cardiol 1991;46:399-418.
10. Klein I, Levey GS: Unusual manifestations of hypothyroidism. Ann Intern Med 1984;144:123-128.
11. Anthonisen P, Holst E, Thomsen AA: Determination of cardiac output and other hemodynamic data in patients with hyper- and hypo-thyroidism, using dye dilution technique. Scand J Clin Lab Invest 1960;12:472-480.
12. Giannattasio C, Rivolta MR, Failla M, et al: Large- and medium-sized artery abnormalities in untreated and treated hypothyroidism. Eur Heart J 1997;18:1492-1498.
13. Lekakis J, Papamichael C, Alevizaki M, et al: Flow-mediated, endothelium-dependent vasodilation is impaired in subjects with hypothyroidism, borderline hypothyroidism, and high-normal serum thyrotropin (TSH) values. Thyroid 1997;7:411-414.
14. Klemperer JD, Klein I, Gomez M, et al: Thyroid hormone treatment after coronary-artery bypass surgery. N Engl J Med 1995;333:1522-1527.
15. Ojamaa K, Balkman C, Klein IL: Acute effects of triiodothyronine on arterial smooth muscle cells. Ann Thorac Surg 1993;56:61-67.
16. Hak AE, Pols HAP, Visser TJ, et al: Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: The Rotterdam Study. Ann Intern Med 2000;132:270-278.
17. Hussein WI, Green R, Jacobsen DW, Faiman C: Normalization of hyperhomocysteinemia with L-thyroxine in hypothyroidism. Ann Intern Med 1999;131:348-351.
18. Lien EA, Nedrebo BG, Varhaug JE, et al: Plasma total homocysteine levels during short-term iatrogenic hypothyroidism. J Clin Endocrinol Metab 2000;85:1049-1053.
19. Sengul E, Cetinarslan B, Tarkun I, et al: Homocysteine concentrations in subclinical hypothyroidism. Endocr Res 2004;30:351-359.
20. Gibson CM, et al;for the TIMI 4 Study Group: TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996;93:879-888.
21. Epstein SE, Cannon O, Talbot TL: Hemodynamic principles in the control of coronary blood flow. Am J Cardiol 1985;56:4E-10E.
22. Mangieri E, Macchiarelli G, Ciavolella M, et al: Slow coronary flow: clinical and histopathological features in patients with otherwise normal epicardial coronary arteries. Cathet Cardiovasc Diagn 1996;37:375-381.
23. Mosseri M, Yarom R, Gotsman MS, et al: Histologic evidence for small-vessel coronary artery disease in patients with angina and patent large coronary arteries. Circulation 1986;74:964-972.
24. Kurtoglu N, Akcay A, Dindar I: Usefulness of oral dipyridamole therapy for angiographic slow coronary artery flow. Am J Cardiol 2001;87:777-779.
25. Camsari A, Pekdemir H, Cicek D, et al: Endothelin-1 and nitric oxide concentrations and their response to exercise in patients with slow coronary flow. Circ J 2003;67:1022-1028.
26. Lentz SR, Sobey CG, Piegors DJ, et al: Vascular dysfunction in monkeys with diet-induced hyperhomocystein(e)mia. J Clin Invest 1996;98:24-29.
27. Nygard O, Nordrehaug JE, Refsum H, et al: Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 1997;337:230-236.
28. Heinecke JW, Kawamura M, Suzuki L, Chait A: Oxidation of low density lipoprotein by thiols: superoxide-dependent and -independent mechanisms. J Lipid Res 1993;34:2051-2061.
29. Loscalzo J: The oxidation stress of hyperhomcyst(e)inemia. J Clin Invest 1996;98:5-7.
30. Stanger O, Semmelrock HJ, Wonisch W, et al: Effects of folate treatment and homocysteine lowering on resistance vessel reactivity in atherosclerotic subjects. J Pharmacol Exp Ther 2002;303:158-162.
31. Willems FF, Aengevaeren WR, Boers GH, et al: Coronary endothelial function in hyperhomocysteinemia: improvement after treatment with folic acid and cobalamin in patients with coronary artery disease. J Am Coll Cardiol 2002;40:766-772.
32. Fowler PB, Ikram H, Banim SO: Serum-cholesterol, thyroid failure, and coronary-artery disease. Lancet 1972;1:685.
33. Meier C, Staub JJ, Roth CB, et al: TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothyroidism: a double blind, placebo-controlled trial (Basel Thyroid Study). J Clin Endocrinol Metab 2001;86:4860-4866.
34. Muller B, Tsakiris DA, Roth CB, et al: Haemostatic profile in hypothyroidism as potential risk factor for vascular or thrombotic disease. Eur J Clin Invest 2001;31:131-137.
35. Bengel FM, Nekolla SG, Ibrahim T, et al: Effect of thyroid hormones on cardiac function, geometry, and oxidative metabolism assessed non-invasively by positron emission tomography and magnetic resonance imaging. J Clin Endocrinol Metab 2000;85:1822-1827.
36. Kies PP, Stegger L, Wichter T, et al: Myocardial blood flow and coronary vascular resistance are dependent on thyroid function - a quantitative study using positron emission tomography and oxygen-15-labeled water. J Nucl Cardiol 2005;12(suppl 1):S64.
37. Crain MC, Meier C, Guglielmetti M, et al: Elevated C-reactive protein and homocysteine values: cardiovascular risk factors in hypothyroidism? A cross-sectional and a double-blind, placebo-controlled trial. Atherosclerosis 2003;166:379-386.
38. Kreisman SH, Hennessey JV: Consistent reversible elevations of serum creatinine levels in severe hypothyroidism. Arch Intern Med 1999;159:79-82.
39. Shane B, Stokstad EL: Vitamin B12-folate interrelationships. Annu Rev Nutr 1985;5:115-141.
40. Langton JE, Brent GA: Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients. Endocrinol Metab Clin North Am 2002;31:159-172.
41. McIver B, Gorman CA: Euthyroid sick syndrome: an overview. Thyroid 1997;7:125-132.
42. Potkin BN, Bartorelli AL, Gessert JM, et al: Coronary artery imaging with intravascular high-frequency ultrasound. Circulation 1990;81:1575-1585.