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As CM is a reversible process, the TON (turnover number) represents the average number of substrate molecules converted into the cross product per molecule of catalyst. A typical loading of 1a,b in CM reaction is 2-10%, which corresponds to a maximum TON of 10-50. For a recent TON study in ruthenium carbene catalyzed ring-closing metathesis, see: Maechling, S.; Zaja, M.; Blechert, S. Adv. Synth. Catal. 2005, 347, 1413.
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As CM is a reversible process, the TON (turnover number) represents the average number of substrate molecules converted into the cross product per molecule of catalyst. A typical loading of 1a,b in CM reaction is 2-10%, which corresponds to a maximum TON of 10-50. For a recent TON study in ruthenium carbene catalyzed ring-closing metathesis, see: Maechling, S.; Zaja, M.; Blechert, S. Adv. Synth. Catal. 2005, 347, 1413.
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