메뉴 건너뛰기




Volumn 30, Issue 9, 2007, Pages 1055-1061

Synthesis and biological activity of 5-{4-[2-(Methyl-p-substituted phenylamino)ethoxy]benzyl}thiazolidine-2,4-diones

Author keywords

Diabetes; Inflammation; Nitric oxide; PPAR ; Thiazolidinedione

Indexed keywords


EID: 34848902890     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02980237     Document Type: Article
Times cited : (22)

References (21)
  • 1
    • 0036554139 scopus 로고    scopus 로고
    • Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-gamma: Counter-regulatory activity by IFN-gamma
    • Alleva, D. G., Johnson, E. B., Lio, F. M., Boehme, S. A., Conlon, P. J., and Crowe, P. D., Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-gamma: counter-regulatory activity by IFN-gamma. J. Leukoc. Biol., 71, 677-685 (2002).
    • (2002) J. Leukoc. Biol , vol.71 , pp. 677-685
    • Alleva, D.G.1    Johnson, E.B.2    Lio, F.M.3    Boehme, S.A.4    Conlon, P.J.5    Crowe, P.D.6
  • 2
    • 0033754530 scopus 로고    scopus 로고
    • Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: A 6-month randomized placebo-controlled dose-response study. The Pioglitazone 001 Study Group
    • Aronoff, S., Rosenblatt, S., Braithwaite, S., Egan, J. W., Mathisen, A. L., and Schneider, R. L., Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: a 6-month randomized placebo-controlled dose-response study. The Pioglitazone 001 Study Group. Diabetes Care, 23, 1605-1611 (2000).
    • (2000) Diabetes Care , vol.23 , pp. 1605-1611
    • Aronoff, S.1    Rosenblatt, S.2    Braithwaite, S.3    Egan, J.W.4    Mathisen, A.L.5    Schneider, R.L.6
  • 3
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger, J. and Moller, D. E., The mechanisms of action of PPARs. Annu. Rev. Med., 53, 409-435 (2002).
    • (2002) Annu. Rev. Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 5
    • 0032528350 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase by peroxisome proliferator- activated receptor agonists: Correlation with induction of heme oxygenase 1
    • Colville-Nash, P. R., Qureshi, S. S., Willis, D., and Willoughby, D. A., Inhibition of inducible nitric oxide synthase by peroxisome proliferator- activated receptor agonists: correlation with induction of heme oxygenase 1. J. Immunol., 161, 978-984 (1998).
    • (1998) J. Immunol , vol.161 , pp. 978-984
    • Colville-Nash, P.R.1    Qureshi, S.S.2    Willis, D.3    Willoughby, D.A.4
  • 6
    • 20444393107 scopus 로고    scopus 로고
    • A novel PPAR response element in the murine iNOS promoter
    • Crosby, M. B., Svenson, J., Gilkeson, G. S., and Nowling, T. K., A novel PPAR response element in the murine iNOS promoter. Mol. Immunol., 42, 1303-1310 (2005).
    • (2005) Mol. Immunol , vol.42 , pp. 1303-1310
    • Crosby, M.B.1    Svenson, J.2    Gilkeson, G.S.3    Nowling, T.K.4
  • 7
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne, B. and Wahli, W., Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev., 20, 649-688 (1999).
    • (1999) Endocr. Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 8
    • 0034665083 scopus 로고    scopus 로고
    • Troglitazone inhibits the expression of inducible nitric oxide synthase in adipocytes in vitro and in vivo study in 3T3-L1 cells and Otsuka Long-Evans Tokushima Fatty rats
    • Dobashi, K., Asayama, K., Nakane, T., Kodera, K., Hayashibe, H., and Nakazawa, S., Troglitazone inhibits the expression of inducible nitric oxide synthase in adipocytes in vitro and in vivo study in 3T3-L1 cells and Otsuka Long-Evans Tokushima Fatty rats. Life Sci., 67, 2093-2101 (2000).
    • (2000) Life Sci , vol.67 , pp. 2093-2101
    • Dobashi, K.1    Asayama, K.2    Nakane, T.3    Kodera, K.4    Hayashibe, H.5    Nakazawa, S.6
  • 9
    • 0033378706 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase
    • Heneka, M. T., Feinstein, D. L., Galea, E., Gleichmann, M., Wullner, U., and Klockgether, T., Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase. J. Neuroimmunol., 100, 156-168 (1999).
    • (1999) J. Neuroimmunol , vol.100 , pp. 156-168
    • Heneka, M.T.1    Feinstein, D.L.2    Galea, E.3    Gleichmann, M.4    Wullner, U.5    Klockgether, T.6
  • 10
    • 7844224790 scopus 로고    scopus 로고
    • Henke, B. R., Blanchard, S. G., Brackeen, M. F., Brown, K. K., Cobb, J. E., Collins, J. L., Harrington, W. W., Jr., Hashim, M. A., Hull-Ryde, E. A., Kaldor, I., Kliewer, S. A., Lake, D. H., Leesnitzer, L. M., Lehmann, J. M., Lenhard, J. M., Orband-Miller, L. A., Miller, J. F., Mook, R. A., Jr., Noble, S. A., Oliver, W., Jr., Parks, D. J., Plunket, K. D., Szewczyk, J. R., and Willson, T. M., N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents. J. Med. Chem., 41, 5020-5036 (1998).
    • Henke, B. R., Blanchard, S. G., Brackeen, M. F., Brown, K. K., Cobb, J. E., Collins, J. L., Harrington, W. W., Jr., Hashim, M. A., Hull-Ryde, E. A., Kaldor, I., Kliewer, S. A., Lake, D. H., Leesnitzer, L. M., Lehmann, J. M., Lenhard, J. M., Orband-Miller, L. A., Miller, J. F., Mook, R. A., Jr., Noble, S. A., Oliver, W., Jr., Parks, D. J., Plunket, K. D., Szewczyk, J. R., and Willson, T. M., N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents. J. Med. Chem., 41, 5020-5036 (1998).
  • 12
    • 0028584172 scopus 로고
    • Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells
    • Ibrahimi, A., Teboul, L., Gaillard, D., Amri, E. Z., Ailhaud, G., Young, P., Cawthorne, M. A., and Grimaldi, P. A., Evidence for a common mechanism of action for fatty acids and thiazolidinedione antidiabetic agents on gene expression in preadipose cells. Mol. Pharmacol., 46, 1070-1076 (1994).
    • (1994) Mol. Pharmacol , vol.46 , pp. 1070-1076
    • Ibrahimi, A.1    Teboul, L.2    Gaillard, D.3    Amri, E.Z.4    Ailhaud, G.5    Young, P.6    Cawthorne, M.A.7    Grimaldi, P.A.8
  • 13
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang, C., Ting, A. T., and Seed, B., PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature, 391, 82-86 (1998).
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 14
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten, S., Desvergne, B., and Wahli, W., Roles of PPARs in health and disease. Nature, 405, 421-424 (2000).
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 15
    • 0026517080 scopus 로고
    • Enhancement of adipocyte differentiation by an insulin-sensitizing agent
    • Kletzien, R. F., Clarke, S. D., and Ulrich, R. G. Enhancement of adipocyte differentiation by an insulin-sensitizing agent. Mol. Pharmacol., 41, 393-398 (1992).
    • (1992) Mol. Pharmacol , vol.41 , pp. 393-398
    • Kletzien, R.F.1    Clarke, S.D.2    Ulrich, R.G.3
  • 16
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A., An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem., 270, 12953-12956 (1995).
    • (1995) J. Biol. Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 19
    • 0034141531 scopus 로고    scopus 로고
    • Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists
    • Reilly, C. M., Oates, J. C., Cook, J. A., Morrow, J. D., Halushka, P. V.,and Gilkeson, G. S., Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists. J. Immunol., 164, 1498-1504 (2000).
    • (2000) J. Immunol , vol.164 , pp. 1498-1504
    • Reilly, C.M.1    Oates, J.C.2    Cook, J.A.3    Morrow, J.D.4    Halushka, P.V.5    Gilkeson, G.S.6
  • 20
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote, M., Li, A. C., Willson, T. M., Kelly, C. J., and Glass, C. K., The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature, 391, 79-82 (1998).
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 21
    • 0025055470 scopus 로고
    • Studies on antidiabetic agents. Synthesis and hypoglycemic activity of 5-[4-(pyridylalkoxy)benzyl]-2,4-thiazolidinediones
    • Sohda, T., Momose, Y., Meguro, K., Kawamatsu, Y., Sugiyama, Y., and Ikeda, H., Studies on antidiabetic agents. Synthesis and hypoglycemic activity of 5-[4-(pyridylalkoxy)benzyl]-2,4-thiazolidinediones. Arzneimittelforschung, 40, 37-42 (1990).
    • (1990) Arzneimittelforschung , vol.40 , pp. 37-42
    • Sohda, T.1    Momose, Y.2    Meguro, K.3    Kawamatsu, Y.4    Sugiyama, Y.5    Ikeda, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.